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Volumn 47, Issue 9, 2008, Pages 2701-2709

Nucleotide selectivity opposite a benzo[a]pyrene-derived N2-dG adduct in a Y-family DNA polymerase: A 5′-slippage mechanism

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; ASSAYS; BACTERIA; CATALYST SELECTIVITY; COMPUTER SIMULATION;

EID: 40149083124     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi701839q     Document Type: Article
Times cited : (25)

References (54)
  • 1
    • 0037115955 scopus 로고    scopus 로고
    • How DNA lesions are turned into mutations within cells
    • Pages, V., and Fuchs, R. P. (2002) How DNA lesions are turned into mutations within cells. Oncogene 21, 8957-8966.
    • (2002) Oncogene , vol.21 , pp. 8957-8966
    • Pages, V.1    Fuchs, R.P.2
  • 2
    • 19444383801 scopus 로고    scopus 로고
    • Trading places: How do DNA polymerases switch during translesion DNA synthesis
    • Friedberg, E. C., Lehmann, A. R., and Fuchs, R. P. (2005) Trading places: How do DNA polymerases switch during translesion DNA synthesis. Mol. Cell 18, 499-505.
    • (2005) Mol. Cell , vol.18 , pp. 499-505
    • Friedberg, E.C.1    Lehmann, A.R.2    Fuchs, R.P.3
  • 3
    • 1942439667 scopus 로고    scopus 로고
    • Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases
    • Plosky, B. S., and Woodgate, R. (2004) Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases. Curr. Opin. Genet. Dev. 14, 113-119.
    • (2004) Curr. Opin. Genet. Dev , vol.14 , pp. 113-119
    • Plosky, B.S.1    Woodgate, R.2
  • 5
    • 33746775293 scopus 로고    scopus 로고
    • Translesion synthesis in mammalian cells
    • Lehmann, A. R. (2006) Translesion synthesis in mammalian cells. Exp. Cell Res. 312, 2673-2676.
    • (2006) Exp. Cell Res , vol.312 , pp. 2673-2676
    • Lehmann, A.R.1
  • 6
    • 21244506437 scopus 로고    scopus 로고
    • Eukaryotic translesion synthesis DNA polymerases: Specificity of structure and function
    • Prakash, S., Johnson, R. E., and Prakash, L. (2005) Eukaryotic translesion synthesis DNA polymerases: Specificity of structure and function. Annu. Rev. Biochem. 74, 317-353.
    • (2005) Annu. Rev. Biochem , vol.74 , pp. 317-353
    • Prakash, S.1    Johnson, R.E.2    Prakash, L.3
  • 7
    • 33644634327 scopus 로고    scopus 로고
    • Interactions of carcinogen-bound DNA with individual DNA polymerases
    • Guengerich, F. P. (2006) Interactions of carcinogen-bound DNA with individual DNA polymerases. Chem. Rev. 106, 420-452.
    • (2006) Chem. Rev , vol.106 , pp. 420-452
    • Guengerich, F.P.1
  • 8
    • 0035890599 scopus 로고    scopus 로고
    • Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): An archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic polη
    • Boudsocq, F., Iwai, S., Hanaoka, F., and Woodgate, R. (2001) Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): An archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic polη. Nucleic Acids Res. 29, 4607-4616.
    • (2001) Nucleic Acids Res , vol.29 , pp. 4607-4616
    • Boudsocq, F.1    Iwai, S.2    Hanaoka, F.3    Woodgate, R.4
  • 9
    • 0034235584 scopus 로고    scopus 로고
    • Error-prone bypass of certain DNA lesions by the human DNA polymerase κ
    • Ohashi, E., Ogi, T., Kusumoto, R., Iwai, S., Masutani, C., Hanaoka, F., and Ohmori, H. (2000) Error-prone bypass of certain DNA lesions by the human DNA polymerase κ. Genes Dev. 14, 1589-1594.
    • (2000) Genes Dev , vol.14 , pp. 1589-1594
    • Ohashi, E.1    Ogi, T.2    Kusumoto, R.3    Iwai, S.4    Masutani, C.5    Hanaoka, F.6    Ohmori, H.7
  • 11
    • 0035812849 scopus 로고    scopus 로고
    • Crystal structure of a Y-family DNA polymerase in action: A mechanism for error-prone and lesion-bypass replication
    • Ling, H., Boudsocq, F., Woodgate, R., and Yang, W. (2001) Crystal structure of a Y-family DNA polymerase in action: A mechanism for error-prone and lesion-bypass replication. Cell 107, 91-102.
    • (2001) Cell , vol.107 , pp. 91-102
    • Ling, H.1    Boudsocq, F.2    Woodgate, R.3    Yang, W.4
  • 12
    • 0041864009 scopus 로고    scopus 로고
    • Replication of a cis-syn thymine dimer at atomic resolution
    • Ling, H., Boudsocq, F., Plosky, B. S., Woodgate, R., and Yang, W. (2003) Replication of a cis-syn thymine dimer at atomic resolution. Nature 424, 1083-1087.
    • (2003) Nature , vol.424 , pp. 1083-1087
    • Ling, H.1    Boudsocq, F.2    Plosky, B.S.3    Woodgate, R.4    Yang, W.5
  • 13
    • 1642382214 scopus 로고    scopus 로고
    • Snapshots of replication through an abasic lesion; structural basis for base substitutions and frameshifts
    • Ling, H., Boudsocq, F., Woodgate, R., and Yang, W. (2004) Snapshots of replication through an abasic lesion; structural basis for base substitutions and frameshifts. Mol. Cell 13, 751-762.
    • (2004) Mol. Cell , vol.13 , pp. 751-762
    • Ling, H.1    Boudsocq, F.2    Woodgate, R.3    Yang, W.4
  • 14
    • 27144542782 scopus 로고    scopus 로고
    • Fidelity of Dpo4: Effect of metal ions, nucleotide selection and pyrophosphorolysis
    • Vaisman, A., Ling, H., Woodgate, R., and Yang, W. (2005) Fidelity of Dpo4: Effect of metal ions, nucleotide selection and pyrophosphorolysis. EMBO J. 24, 2957-2967.
    • (2005) EMBO J , vol.24 , pp. 2957-2967
    • Vaisman, A.1    Ling, H.2    Woodgate, R.3    Yang, W.4
  • 17
    • 3543028588 scopus 로고    scopus 로고
    • Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication
    • Boudsocq, F., Kokoska, R. J., Plosky, B. S., Vaisman, A., Ling, H., Kunkel, T. A., Yang, W., and Woodgate, R. (2004) Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication. J. Biol. Chem. 279, 32932-32940.
    • (2004) J. Biol. Chem , vol.279 , pp. 32932-32940
    • Boudsocq, F.1    Kokoska, R.J.2    Plosky, B.S.3    Vaisman, A.4    Ling, H.5    Kunkel, T.A.6    Yang, W.7    Woodgate, R.8
  • 18
    • 33644866040 scopus 로고    scopus 로고
    • Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4
    • Zang, H., Irimia, A., Choi, J. Y., Angel, K. C., Loukachevitch, L. V., Egli, M., and Guengerich, F. P. (2006) Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4. J. Biol. Chem. 281, 2358-2372.
    • (2006) J. Biol. Chem , vol.281 , pp. 2358-2372
    • Zang, H.1    Irimia, A.2    Choi, J.Y.3    Angel, K.C.4    Loukachevitch, L.V.5    Egli, M.6    Guengerich, F.P.7
  • 20
    • 35448977252 scopus 로고    scopus 로고
    • A structural gap in a Y-family DNA polymerase supports mutagenic bypass of a major benzo[a]pyrene adduct through template misalignment
    • Bauer, J., Xing, G., Yagi, H., Sayer, J. M., Jerina, D. M., and Ling, H. (2007) A structural gap in a Y-family DNA polymerase supports mutagenic bypass of a major benzo[a]pyrene adduct through template misalignment, Proc. Natl. Acad. Sci. U.S.A. 104, 14905-14910.
    • (2007) Proc. Natl. Acad. Sci. U.S.A , vol.104 , pp. 14905-14910
    • Bauer, J.1    Xing, G.2    Yagi, H.3    Sayer, J.M.4    Jerina, D.M.5    Ling, H.6
  • 21
    • 0031883128 scopus 로고    scopus 로고
    • Structural insights into DNA polymerase β fidelity. Hold tight if you want it right
    • Beard, W. A., and Wilson, S. H. (1998) Structural insights into DNA polymerase β fidelity. Hold tight if you want it right. Chem. Biol. 5, R7-R13.
    • (1998) Chem. Biol , vol.5
    • Beard, W.A.1    Wilson, S.H.2
  • 22
    • 0033576703 scopus 로고    scopus 로고
    • Tightening the belt on polymerases: Evaluating the physical constraints on enzyme substrate size
    • Frieden, M., Pedroso, E., and Kool, E. T. (1999) Tightening the belt on polymerases: Evaluating the physical constraints on enzyme substrate size. Angew. Chem., Int. Ed. 38, 3654-3657.
    • (1999) Angew. Chem., Int. Ed , vol.38 , pp. 3654-3657
    • Frieden, M.1    Pedroso, E.2    Kool, E.T.3
  • 23
    • 0030930760 scopus 로고    scopus 로고
    • Crystal structures of human DNA polymerase β complexed with gapped and nicked DNA: Evidence for an induced fit mechanism
    • Sawaya, M. R., Prasad, R., Wilson, S. H., Kraut, J., and Pelletier, H. (1997) Crystal structures of human DNA polymerase β complexed with gapped and nicked DNA: Evidence for an induced fit mechanism. Biochemistry 36, 11205-11215.
    • (1997) Biochemistry , vol.36 , pp. 11205-11215
    • Sawaya, M.R.1    Prasad, R.2    Wilson, S.H.3    Kraut, J.4    Pelletier, H.5
  • 24
    • 0026026192 scopus 로고
    • An induced-fit kinetic mechanism for DNA replication fidelity: Direct measurement by single-turnover kinetics
    • Wong, I., Patel, S. S., and Johnson, K. A. (1991) An induced-fit kinetic mechanism for DNA replication fidelity: Direct measurement by single-turnover kinetics. Biochemistry 30, 526-537.
    • (1991) Biochemistry , vol.30 , pp. 526-537
    • Wong, I.1    Patel, S.S.2    Johnson, K.A.3
  • 25
    • 0032515080 scopus 로고    scopus 로고
    • Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions
    • Beard, W. A., Bebenek, K., Darden, T. A., Li, L., Prasad, R., Kunkel, T. A., and Wilson, S. H. (1998) Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions. J. Biol. Chem. 273, 30435-30442.
    • (1998) J. Biol. Chem , vol.273 , pp. 30435-30442
    • Beard, W.A.1    Bebenek, K.2    Darden, T.A.3    Li, L.4    Prasad, R.5    Kunkel, T.A.6    Wilson, S.H.7
  • 27
    • 0034686025 scopus 로고    scopus 로고
    • Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove
    • Latham, G. J., Forgacs, E., Beard, W. A., Prasad, R., Bebenek, K., Kunkel, T. A., Wilson, S. H., and Lloyd, R. S. (2000) Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove. J. Biol. Chem. 275, 15025-15033.
    • (2000) J. Biol. Chem , vol.275 , pp. 15025-15033
    • Latham, G.J.1    Forgacs, E.2    Beard, W.A.3    Prasad, R.4    Bebenek, K.5    Kunkel, T.A.6    Wilson, S.H.7    Lloyd, R.S.8
  • 28
    • 0033577360 scopus 로고    scopus 로고
    • Minor groove interactions between polymerase and DNA: More essential to replication than Watson-Crick hydrogen bonds
    • Morales, J., and Kool, E. T. (1999) Minor groove interactions between polymerase and DNA: More essential to replication than Watson-Crick hydrogen bonds. J. Am. Chem. Soc. 121, 2323-2324.
    • (1999) J. Am. Chem. Soc , vol.121 , pp. 2323-2324
    • Morales, J.1    Kool, E.T.2
  • 29
    • 0026713678 scopus 로고
    • Side chains involved in catalysis of the polymerase reaction of DNA polymerase I from Escherichia coli
    • Polesky, A. H., Dahlberg, M. E., Benkovic, S. J., Grindley, N. D., and Joyce, C. M. (1992) Side chains involved in catalysis of the polymerase reaction of DNA polymerase I from Escherichia coli. J. Biol. Chem. 267, 8417-8428.
    • (1992) J. Biol. Chem , vol.267 , pp. 8417-8428
    • Polesky, A.H.1    Dahlberg, M.E.2    Benkovic, S.J.3    Grindley, N.D.4    Joyce, C.M.5
  • 30
    • 0034762679 scopus 로고    scopus 로고
    • Crystal structure of a DinB family error-prone DNA polymerase from Sulfolobus solfataricus
    • Silvian, L. F., Toth, E. A., Pham, P., Goodman, M. F., and Ellenberger, T. (2001) Crystal structure of a DinB family error-prone DNA polymerase from Sulfolobus solfataricus. Nat. Struct. Biol. 8, 984-989.
    • (2001) Nat. Struct. Biol , vol.8 , pp. 984-989
    • Silvian, L.F.1    Toth, E.A.2    Pham, P.3    Goodman, M.F.4    Ellenberger, T.5
  • 31
    • 0034847259 scopus 로고    scopus 로고
    • Structure of the catalytic core of S. cerevisiae DNA polymerase η: Implications for translesion DNA synthesis
    • Trincao, J., Johnson, R. E., Escalante, C. R., Prakash, S., Prakash, L., and Aggarwal, A. K. (2001) Structure of the catalytic core of S. cerevisiae DNA polymerase η: Implications for translesion DNA synthesis. Mol. Cell 8, 417-426.
    • (2001) Mol. Cell , vol.8 , pp. 417-426
    • Trincao, J.1    Johnson, R.E.2    Escalante, C.R.3    Prakash, S.4    Prakash, L.5    Aggarwal, A.K.6
  • 32
    • 0020431144 scopus 로고    scopus 로고
    • Conney, A. H. (1982) Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture. Cancer Res. 42, 4875-4917.
    • Conney, A. H. (1982) Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture. Cancer Res. 42, 4875-4917.
  • 33
    • 0000933858 scopus 로고
    • Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: Exceptional activity of (+)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9, 10-tetrahydrobenzo[a]pyrene
    • Buening, M. K., Wislocki, P. G., Levin, W., Yagi, H., Thakker, D. R., Akagi, H., Koreeda, M., Jerina, D. M., and Conney, A. H. (1978) Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: Exceptional activity of (+)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9, 10-tetrahydrobenzo[a]pyrene. Proc. Natl. Acad. Sci. U.S.A. 75, 5358-5361.
    • (1978) Proc. Natl. Acad. Sci. U.S.A , vol.75 , pp. 5358-5361
    • Buening, M.K.1    Wislocki, P.G.2    Levin, W.3    Yagi, H.4    Thakker, D.R.5    Akagi, H.6    Koreeda, M.7    Jerina, D.M.8    Conney, A.H.9
  • 34
    • 0031910204 scopus 로고    scopus 로고
    • DNA adduct formation by polycyclic aromatic hydrocarbon dihydrodiol epoxides
    • Szeliga, J., and Dipple, A. (1998) DNA adduct formation by polycyclic aromatic hydrocarbon dihydrodiol epoxides. Chem. Res. Toxicol. 11, 1-11.
    • (1998) Chem. Res. Toxicol , vol.11 , pp. 1-11
    • Szeliga, J.1    Dipple, A.2
  • 35
    • 0024442239 scopus 로고
    • DNA adducts from carcinogenic and noncarcinogenic enantiomers of benzo[a]pyrene dihydrodiol epoxide
    • Cheng, S. C., Hilton, B. D., Roman, J. M., and Dipple, A. (1989) DNA adducts from carcinogenic and noncarcinogenic enantiomers of benzo[a]pyrene dihydrodiol epoxide. Chem. Res. Toxicol. 2, 334-340.
    • (1989) Chem. Res. Toxicol , vol.2 , pp. 334-340
    • Cheng, S.C.1    Hilton, B.D.2    Roman, J.M.3    Dipple, A.4
  • 36
    • 0031041812 scopus 로고    scopus 로고
    • NMR solution structures of stereoisometric covalent polycyclic aromatic carcinogen - DNA adduct: Principles, patterns, and diversity
    • Geacintov, N. E., Cosman, M., Hingerty, B. E., Amin, S., Broyde, S., and Patel, D. J. (1997) NMR solution structures of stereoisometric covalent polycyclic aromatic carcinogen - DNA adduct: Principles, patterns, and diversity. Chem. Res. Toxicol. 10, 111-146.
    • (1997) Chem. Res. Toxicol , vol.10 , pp. 111-146
    • Geacintov, N.E.1    Cosman, M.2    Hingerty, B.E.3    Amin, S.4    Broyde, S.5    Patel, D.J.6
  • 37
    • 0018425446 scopus 로고
    • Double-stranded DNA steroselectively binds benzo[a]pyrene diol epoxides
    • Meehan, T., and Straub, K. (1979) Double-stranded DNA steroselectively binds benzo[a]pyrene diol epoxides. Nature 277, 410-412.
    • (1979) Nature , vol.277 , pp. 410-412
    • Meehan, T.1    Straub, K.2
  • 38
    • 4344596952 scopus 로고    scopus 로고
    • The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: Elucidating the structure-function relationship through experimental and computational approaches
    • Perlow-Poehnelt, R. A., Likhterov, I., Scicchitano, D. A., Geacintov, N. E., and Broyde, S. (2004) The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: Elucidating the structure-function relationship through experimental and computational approaches. J. Biol. Chem. 279, 36951-36961.
    • (2004) J. Biol. Chem , vol.279 , pp. 36951-36961
    • Perlow-Poehnelt, R.A.1    Likhterov, I.2    Scicchitano, D.A.3    Geacintov, N.E.4    Broyde, S.5
  • 39
    • 40149110948 scopus 로고    scopus 로고
    • Chemistry Department, New York University, New York
    • 2-dG Adducts, Chemistry Department, New York University, New York.
    • (2007) 2-dG Adducts
    • Oum, L.1
  • 40
    • 0035810955 scopus 로고    scopus 로고
    • Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo-Klenow fragment of Pol I
    • Zhuang, P., Kolbanovskiy, A., Amin, S., and Geacintov, N. E. (2001) Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo-Klenow fragment of Pol I. Biochemistry 40, 6660-6669.
    • (2001) Biochemistry , vol.40 , pp. 6660-6669
    • Zhuang, P.1    Kolbanovskiy, A.2    Amin, S.3    Geacintov, N.E.4
  • 42
    • 0031870798 scopus 로고    scopus 로고
    • Effect of single benzo[a]pyrene diol epoxidedeoxyguanosine adducts on the action of DNA polymerases in vitro
    • Lipinski, L. J., Ross, H. L., Zajc, B., Sayer, J. M., Jerina, D. M., and Dipple, A. (1998) Effect of single benzo[a]pyrene diol epoxidedeoxyguanosine adducts on the action of DNA polymerases in vitro. Int. J. Oncol. 13, 269-273.
    • (1998) Int. J. Oncol , vol.13 , pp. 269-273
    • Lipinski, L.J.1    Ross, H.L.2    Zajc, B.3    Sayer, J.M.4    Jerina, D.M.5    Dipple, A.6
  • 43
    • 0027185882 scopus 로고
    • Translesional synthesis on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE (7,8-dihydroxy-anti-9,10- epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene)
    • Shibutani, S., Margulis, L. A., Geacintov, N. E., and Grollman, A. P. (1993) Translesional synthesis on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE (7,8-dihydroxy-anti-9,10- epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene). Biochemistry 32, 7531-7541.
    • (1993) Biochemistry , vol.32 , pp. 7531-7541
    • Shibutani, S.1    Margulis, L.A.2    Geacintov, N.E.3    Grollman, A.P.4
  • 44
    • 34547829269 scopus 로고    scopus 로고
    • 2-dG adduct through replication: Elucidating blockage and bypass in a high-fidelity DNA polymerase
    • 2-dG adduct through replication: Elucidating blockage and bypass in a high-fidelity DNA polymerase, Nucleic Acids Res., 35, 4275-4288.
    • (2007) Nucleic Acids Res , vol.35 , pp. 4275-4288
    • Xu, P.1    Oum, L.2    Beese, L.S.3    Geacintov, N.E.4    Broyde, S.5
  • 48
    • 0033537638 scopus 로고    scopus 로고
    • Stereochemical origin of opposite orientations in DNA adducts derived from enantiomeric anti-benzo[a]pyrene diol epoxides with different tumorigenic potentials
    • Xie, X. M., Geacintov, N. E., and Broyde, S. (1999) Stereochemical origin of opposite orientations in DNA adducts derived from enantiomeric anti-benzo[a]pyrene diol epoxides with different tumorigenic potentials. Biochemistry 38, 2956-2968.
    • (1999) Biochemistry , vol.38 , pp. 2956-2968
    • Xie, X.M.1    Geacintov, N.E.2    Broyde, S.3
  • 49
    • 0036382913 scopus 로고    scopus 로고
    • Toward understanding the mutagenicity of an environmental carcinogen: Structural insights into nucleotide incorporation preferences
    • Perlow, R. A., and Broyde, S. (2002) Toward understanding the mutagenicity of an environmental carcinogen: Structural insights into nucleotide incorporation preferences. J. Mol. Biol. 322, 291-309.
    • (2002) J. Mol. Biol , vol.322 , pp. 291-309
    • Perlow, R.A.1    Broyde, S.2
  • 51
    • 33645984577 scopus 로고    scopus 로고
    • Magnesium-induced assembly of a complete DNA polymerase catalytic complex
    • Batra, V. K., Beard, W. A., Shock, D. D., Krahn, J. M., Pedersen, L. C., and Wilson, S. H. (2006) Magnesium-induced assembly of a complete DNA polymerase catalytic complex. Structure 14, 757-766.
    • (2006) Structure , vol.14 , pp. 757-766
    • Batra, V.K.1    Beard, W.A.2    Shock, D.D.3    Krahn, J.M.4    Pedersen, L.C.5    Wilson, S.H.6
  • 52
    • 0034235584 scopus 로고    scopus 로고
    • Error-prone bypass of certain DNA lesions by the human DNA polymerase κ
    • Ohashi, E., Ogi, T., Kusumoto, R., Iwai, S., Masutani, C., Hanaoka, F., and Ohmori, H. (2000) Error-prone bypass of certain DNA lesions by the human DNA polymerase κ. Genes Dev. 14, 1589-1594.
    • (2000) Genes Dev , vol.14 , pp. 1589-1594
    • Ohashi, E.1    Ogi, T.2    Kusumoto, R.3    Iwai, S.4    Masutani, C.5    Hanaoka, F.6    Ohmori, H.7
  • 54
    • 33645328816 scopus 로고    scopus 로고
    • Mirror image stereoisomers of the major benzo[a]pyrene N2-dG adduct are bypassed by different lesion-bypass polymerases in E. coli
    • Seo, K.-Y., Nagalingam, A., Shadi Miri, J. Y., Kolbanovskiy, A., Shastry, A., and Loechler, E. L. (2006) Mirror image stereoisomers of the major benzo[a]pyrene N2-dG adduct are bypassed by different lesion-bypass polymerases in E. coli. DNA Repair 5, 515-522.
    • (2006) DNA Repair , vol.5 , pp. 515-522
    • Seo, K.-Y.1    Nagalingam, A.2    Shadi Miri, J.Y.3    Kolbanovskiy, A.4    Shastry, A.5    Loechler, E.L.6


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