Stereochemical origin of opposite orientations in DNA adducts derived from enantiomeric anti-benzo[a]pyrene diol epoxides with different tumorigenic potentials

Biochemistry

Volumn 38, Issue 10, 1999, Pages 2956-2968

  Xie, Xiao Ming ^a   Geacintov, Nicholas E ^a   Broyde, Suse ^a  

^a NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC POLYMERS; CARCINOGENS; CONFORMATIONS; DNA; ENZYMES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POTENTIAL ENERGY; STEREOCHEMISTRY; SURFACES;

AROMATIC DIOL EPOXIDES; AROMATIC MOIETY; STEREOISOMER; TUMORIGENIC POTENTIALS;

MOLECULAR ORIENTATION;

DEOXYGUANOSINE; DIHYDROXYBENZO[A]PYRENE OXIDE; DOUBLE STRANDED DNA; EPOXIDE; GUANINE; NUCLEOSIDE;

ARTICLE; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; DNA ADDUCT; ENANTIOMER; INTERCALATION COMPLEX; MOLECULAR DYNAMICS; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; SPATIAL ORIENTATION; STEREOCHEMISTRY; STEREOISOMERISM; STEREOSPECIFICITY; THERMAL ANALYSIS;

BENZOPYRENES; CARCINOGENS; DNA ADDUCTS; MATHEMATICAL COMPUTING; MODELS, CHEMICAL; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HETERODUPLEXES; STEREOISOMERISM; THERMODYNAMICS;

EID: 0033537638     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9825605     Document Type: Article

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