메뉴 건너뛰기




Volumn 8, Issue , 2008, Pages

Low-level HIV-1 replication and the dynamics of the resting CD4+ T cell reservoir for HIV-1 in the setting of HAART

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT;

EID: 39749112383     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-8-2     Document Type: Article
Times cited : (53)

References (70)
  • 1
    • 0028792184 scopus 로고
    • In vivo fate of HIV-1-infected T cells: Quantitative analysis of the transition to stable latency
    • 10.1038/nm1295-1284 7489410
    • Chun TW Finzi D Margolick J Chadwick K Schwartz D Siliciano RF: In vivo fate of HIV-1-infected T cells: Quantitative analysis of the transition to stable latency. Nat Med 1995, 1:1284-1290. 10.1038/nm1295-1284 7489410
    • (1995) Nat Med , vol.1 , pp. 1284-1290
    • Chun, T.W.1    Finzi, D.2    Margolick, J.3    Chadwick, K.4    Schwartz, D.5    Siliciano, R.F.6
  • 5
    • 0038468339 scopus 로고    scopus 로고
    • Analysis of human immunodeficiency virus type 1 gene expression in latently infected resting CD4+ T lymphocytes in vivo
    • 164778 12805437 10.1128/JVI.77.13.7383-7392.2003
    • Hermankova M Siliciano JD Zhou Y Monie D Chadwick K Margolick JB Quinn TC Siliciano RF: Analysis of human immunodeficiency virus type 1 gene expression in latently infected resting CD4+ T lymphocytes in vivo. J Virol 2003, 77:7383-7392. 164778 12805437 10.1128/ JVI.77.13.7383-7392.2003
    • (2003) J Virol , vol.77 , pp. 7383-7392
    • Hermankova, M.1    Siliciano, J.D.2    Zhou, Y.3    Monie, D.4    Chadwick, K.5    Margolick, J.B.6    Quinn, T.C.7    Siliciano, R.F.8
  • 6
    • 4143061435 scopus 로고    scopus 로고
    • Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo
    • 506937 15308706 10.1128/JVI.78.17.9105-9114.2004
    • Lassen KG Bailey JR Siliciano RF: Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo. J Virol 2004, 78:9105-9114. 506937 15308706 10.1128/ JVI.78.17.9105-9114.2004
    • (2004) J Virol , vol.78 , pp. 9105-9114
    • Lassen, K.G.1    Bailey, J.R.2    Siliciano, R.F.3
  • 13
    • 0033609374 scopus 로고    scopus 로고
    • Persistence of HIV-1 transcription in peripheral-blood mononuclear cells in patients receiving potent antiretroviral therapy
    • 10.1056/NEJM199905273402102 10341273
    • Furtado MR Callaway DS Phair JP Kunstman KJ Stanton JL Macken CA Perelson AS Wolinsky SM: Persistence of HIV-1 transcription in peripheral-blood mononuclear cells in patients receiving potent antiretroviral therapy. N Engl J Med 1999, 340:1614-1622. 10.1056/ NEJM199905273402102 10341273
    • (1999) N Engl J Med , vol.340 , pp. 1614-1622
    • Furtado, M.R.1    Callaway, D.S.2    Phair, J.P.3    Kunstman, K.J.4    Stanton, J.L.5    Macken, C.A.6    Perelson, A.S.7    Wolinsky, S.M.8
  • 14
    • 0141676556 scopus 로고    scopus 로고
    • Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive antiretroviral therapy for five years
    • 224988 14512569 10.1128/JVI.77.20.11212-11219.2003
    • Havlir DV Strain MC Clerici M Ignacio C Trabattoni D Ferrante P Wong JK: Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive antiretroviral therapy for five years. J Virol 2003, 77:11212-11219. 224988 14512569 10.1128/JVI.77.20.11212-11219.2003
    • (2003) J Virol , vol.77 , pp. 11212-11219
    • Havlir, D.V.1    Strain, M.C.2    Clerici, M.3    Ignacio, C.4    Trabattoni, D.5    Ferrante, P.6    Wong, J.K.7
  • 15
    • 0035173896 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 quasi species that rebound after discontinuation of highly active antiretroviral therapy are similar to the viral quasi species present before initiation of therapy
    • 10.1086/317641 11106537
    • Imamichi H Crandall KA Natarajan V Jiang MK Dewar RL Berg S Gaddam A Bosche M Metcalf JA Davey RT Jr Lane HC: Human immunodeficiency virus type 1 quasi species that rebound after discontinuation of highly active antiretroviral therapy are similar to the viral quasi species present before initiation of therapy. J Infect Dis 2001, 183:36-50. 10.1086/ 317641 11106537
    • (2001) J Infect Dis , vol.183 , pp. 36-50
    • Imamichi, H.1    Crandall, K.A.2    Natarajan, V.3    Jiang, M.K.4    Dewar, R.L.5    Berg, S.6    Gaddam, A.7    Bosche, M.8    Metcalf, J.A.9    Davey Jr., R.T.10    Lane, H.C.11
  • 16
    • 0033537355 scopus 로고    scopus 로고
    • HIV-1 replication in patients with undetectable plasma virus receiving HAART. Highly active antiretroviral therapy
    • 10.1016/S0140-6736(05)76156-0 10023903
    • Natarajan V Bosche M Metcalf JA Ward DJ Lane HC Kovacs JA: HIV-1 replication in patients with undetectable plasma virus receiving HAART. Highly active antiretroviral therapy. Lancet 1999, 353:119-120. 10.1016/ S0140-6736(05)76156-0 10023903
    • (1999) Lancet , vol.353 , pp. 119-120
    • Natarajan, V.1    Bosche, M.2    Metcalf, J.A.3    Ward, D.J.4    Lane, H.C.5    Kovacs, J.A.6
  • 17
    • 22544461340 scopus 로고    scopus 로고
    • Evidence that low-level viremias during effective highly active antiretroviral therapy result from two processes: Expression of archival virus and replication of virus
    • 1181593 16014925 10.1128/JVI.79.15.9625-9634.2005
    • Tobin NH Learn GH Holte SE Wang Y Melvin AJ McKernan JL Pawluk DM Mohan KM Lewis PF Mullins JI Frenkel LM: Evidence that low-level viremias during effective highly active antiretroviral therapy result from two processes: Expression of archival virus and replication of virus. J Virol 2005, 79:9625-9634. 1181593 16014925 10.1128/ JVI.79.15.9625-9634.2005
    • (2005) J Virol , vol.79 , pp. 9625-9634
    • Tobin, N.H.1    Learn, G.H.2    Holte, S.E.3    Wang, Y.4    Melvin, A.J.5    McKernan, J.L.6    Pawluk, D.M.7    Mohan, K.M.8    Lewis, P.F.9    Mullins, J.I.10    Frenkel, L.M.11
  • 19
    • 0033984045 scopus 로고    scopus 로고
    • The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy
    • 10.1038/71577 10613829
    • Ramratnam B Mittler JE Zhang L Boden D Hurley A Fang F Macken CA Perelson AS Markowitz M Ho DD; The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy. Nat Med 2000, 6:82-85. 10.1038/71577 10613829
    • (2000) Nat Med , vol.6 , pp. 82-85
    • Ramratnam, B.1    Mittler, J.E.2    Zhang, L.3    Boden, D.4    Hurley, A.5    Fang, F.6    Macken, C.A.7    Perelson, A.S.8    Markowitz, M.9    Ho, D.D.10
  • 20
    • 9144265028 scopus 로고    scopus 로고
    • Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replication
    • 10.1097/00126334-200401010-00004 14707789
    • Ramratnam B Ribeiro R He T Chung C Simon V Vanderhoeven J Hurley A Zhang L Perelson AS Ho DD Markowitz M: Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replication. J Acquir Immune Defic Syndr 2004, 35:33-37. 10.1097/00126334-200401010-00004 14707789
    • (2004) J Acquir Immune Defic Syndr , vol.35 , pp. 33-37
    • Ramratnam, B.1    Ribeiro, R.2    He, T.3    Chung, C.4    Simon, V.5    Vanderhoeven, J.6    Hurley, A.7    Zhang, L.8    Perelson, A.S.9    Ho, D.D.10    Markowitz, M.11
  • 22
    • 3543125970 scopus 로고    scopus 로고
    • A long-term latent reservoir for HIV-1: Discovery and clinical implications
    • 10.1093/jac/dkh292 15163657
    • Siliciano JD Siliciano RF: A long-term latent reservoir for HIV-1: discovery and clinical implications. J Antimicrob Chemother 2004, 54:6-9. 10.1093/jac/dkh292 15163657
    • (2004) J Antimicrob Chemother , vol.54 , pp. 6-9
    • Siliciano, J.D.1    Siliciano, R.F.2
  • 25
    • 9144270766 scopus 로고    scopus 로고
    • Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loads
    • 368798 14694128 10.1128/JVI.78.2.968-979.2004
    • Persaud D Siberry GK Ahonkhai A Kajdas J Monie D Hutton N Watson DC Quinn TC Ray SC Siliciano RF: Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loads. J Virol 2004, 78:968-979. 368798 14694128 10.1128/JVI.78.2.968-979.2004
    • (2004) J Virol , vol.78 , pp. 968-979
    • Persaud, D.1    Siberry, G.K.2    Ahonkhai, A.3    Kajdas, J.4    Monie, D.5    Hutton, N.6    Watson, D.C.7    Quinn, T.C.8    Ray, S.C.9    Siliciano, R.F.10
  • 26
    • 2142829435 scopus 로고    scopus 로고
    • Genotypic analysis of HIV-1 drug resistance at the limit of detection: Virus production without evolution in treated adults with undetectable HIV loads
    • 10.1086/382488 15073683
    • Kieffer TL Finucane MM Nettles RE Quinn TC Broman KW Ray SC Persaud D Siliciano RF: Genotypic analysis of HIV-1 drug resistance at the limit of detection: Virus production without evolution in treated adults with undetectable HIV loads. J Infect Dis 2004, 189:1452-1465. 10.1086/382488 15073683
    • (2004) J Infect Dis , vol.189 , pp. 1452-1465
    • Kieffer, T.L.1    Finucane, M.M.2    Nettles, R.E.3    Quinn, T.C.4    Broman, K.W.5    Ray, S.C.6    Persaud, D.7    Siliciano, R.F.8
  • 27
    • 34548424552 scopus 로고    scopus 로고
    • Limits on replenishment of the resting CD4+ T cell reservoir for HIV in patients on HAART
    • 1959378 17784786 10.1371/journal.ppat.0030122
    • Sedaghat AR Siliciano JD Brennan TP Wilke CO Siliciano RF; Limits on replenishment of the resting CD4+ T cell reservoir for HIV in patients on HAART. PLoS Pathog 2007, 3:e122. 1959378 17784786 10.1371/ journal.ppat.0030122
    • (2007) PLoS Pathog , vol.3
    • Sedaghat, A.R.1    Siliciano, J.D.2    Brennan, T.P.3    Wilke, C.O.4    Siliciano, R.F.5
  • 28
    • 0030917156 scopus 로고    scopus 로고
    • Virus dynamics and drug therapy
    • 21269 9192676 10.1073/pnas.94.13.6971
    • Bonhoeffer S May RM Shaw GM Nowak MA: Virus dynamics and drug therapy. Proc Natl Acad Sci USA 1997, 94:6971-6976. 21269 9192676 10.1073/ pnas.94.13.6971
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6971-6976
    • Bonhoeffer, S.1    May, R.M.2    Shaw, G.M.3    Nowak, M.A.4
  • 29
    • 0031581661 scopus 로고    scopus 로고
    • Anti-viral drug treatment: Dynamics of resistance in free virus and infected cell populations
    • 10.1006/jtbi.1996.0307 9059598
    • Nowak MA Bonhoeffer S Shaw GM May RM: Anti-viral drug treatment: dynamics of resistance in free virus and infected cell populations. J Theor Biol 1997, 184:203-217. 10.1006/jtbi.1996.0307 9059598
    • (1997) J Theor Biol , vol.184 , pp. 203-217
    • Nowak, M.A.1    Bonhoeffer, S.2    Shaw, G.M.3    May, R.M.4
  • 30
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time
    • 10.1126/science.271.5255.1582 8599114
    • Perelson AS Neumann AU Markowitz M Leonard JM Ho DD: HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time. Science 1996, 271:1582-1586. 10.1126/ science.271.5255.1582 8599114
    • (1996) Science , vol.271 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 31
  • 32
    • 0032492107 scopus 로고    scopus 로고
    • Target cell limited and immune control models of HIV infection: A comparison
    • 10.1006/jtbi.1997.0548 9514649
    • De Boer RJ Perelson AS: Target cell limited and immune control models of HIV infection: A comparison. J Theor Biol 1998, 190:201-214. 10.1006/ jtbi.1997.0548 9514649
    • (1998) J Theor Biol , vol.190 , pp. 201-214
    • De Boer, R.J.1    Perelson, A.S.2
  • 33
    • 31444440483 scopus 로고    scopus 로고
    • Two types of cytotoxic lymphocyte regulation explain kinetics of immune response to human immunodeficiency virus
    • 1334670 16407101 10.1073/pnas.0510016103
    • Rouzine IM Sergeev RA Glushtsov AI: Two types of cytotoxic lymphocyte regulation explain kinetics of immune response to human immunodeficiency virus. Proc Natl Acad Sci USA 2006, 103:666-671. 1334670 16407101 10.1073/pnas.0510016103
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 666-671
    • Rouzine, I.M.1    Sergeev, R.A.2    Glushtsov, A.I.3
  • 34
    • 0036418504 scopus 로고    scopus 로고
    • What's the matter with HIV-directed killer T cells?
    • 12392972
    • Wick D Self SG: What's the matter with HIV-directed killer T cells? J Theor Biol 2002, 219:19-31. 12392972
    • (2002) J Theor Biol , vol.219 , pp. 19-31
    • Wick, D.1    Self, S.G.2
  • 35
    • 0025639078 scopus 로고
    • The evolutionary dynamics of HIV-1 quasispecies and the development of immunodeficiency disease
    • 10.1097/00002030-199011000-00007 2282182
    • Nowak MA May RM Anderson RM: The evolutionary dynamics of HIV-1 quasispecies and the development of immunodeficiency disease. AIDS 1990, 4:1095-1103. 10.1097/00002030-199011000-00007 2282182
    • (1990) AIDS , vol.4 , pp. 1095-1103
    • Nowak, M.A.1    May, R.M.2    Anderson, R.M.3
  • 36
    • 0037180499 scopus 로고    scopus 로고
    • In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: Why are CD4+ but not CD8+ T cells depleted?
    • 137758 12434018 10.1073/pnas.242358099
    • Ribeiro RM Mohri H Ho DD Perelson AS: In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: Why are CD4+ but not CD8+ T cells depleted?. Proc Natl Acad Sci USA 2002, 99:15572-15577. 137758 12434018 10.1073/pnas.242358099
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15572-15577
    • Ribeiro, R.M.1    Mohri, H.2    Ho, D.D.3    Perelson, A.S.4
  • 37
    • 0036103096 scopus 로고    scopus 로고
    • CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause?
    • 10.1038/nm0402-319 11927927
    • Grossman Z Meier-Schellersheim M Sousa AE Victorino RM Paul WE: CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause?. Nat Med 2002, 8:319-323. 10.1038/nm0402-319 11927927
    • (2002) Nat Med , vol.8 , pp. 319-323
    • Grossman, Z.1    Meier-Schellersheim, M.2    Sousa, A.E.3    Victorino, R.M.4    Paul, W.E.5
  • 38
    • 0033594671 scopus 로고    scopus 로고
    • T-cell induced pathogenesis in HIV: Bystander effects and latent infection
    • 1689939 10380683 10.1098/rspb.1999.0745
    • Krakauer DC Nowak M: T-cell inBuced pathogenesis in HIV: bystander effects and latent infection. Proc Biol Sci 1999, 266:1069-1075. 1689939 10380683 10.1098/rspb.1999.0745
    • (1999) Proc Biol Sci , vol.266 , pp. 1069-1075
    • Krakauer, D.C.1    Nowak, M.2
  • 39
    • 33750451933 scopus 로고    scopus 로고
    • Viral and latent reservoir persistence in HIV-1-infected patients on therapy
    • 1599767 17040122 10.1371/journal.pcbi.0020135
    • Kim H Perelson AS: Viral and latent reservoir persistence in HIV-1-infected patients on therapy. PLoS Comput Biol 2006, 2(10):e135. 1599767 17040122 10.1371/journal.pcbi.0020135
    • (2006) PLoS Comput Biol , vol.2 , Issue.10
    • Kim, H.1    Perelson, A.S.2
  • 40
    • 0031000756 scopus 로고    scopus 로고
    • Human immunodeficiency virus drug therapy and virus load
    • 191463 9060694
    • Bonhoeffer S Coffin JM Nowak MA: Human immunodeficiency virus drug therapy and virus load. J Virol 1997, 71:3275-3278. 191463 9060694
    • (1997) J Virol , vol.71 , pp. 3275-3278
    • Bonhoeffer, S.1    Coffin, J.M.2    Nowak, M.A.3
  • 41
    • 0034040118 scopus 로고    scopus 로고
    • Reservoirs for HIV-1: Mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy
    • 10.1146/annurev.immunol.18.1.665 10837072
    • Pierson T McArthMr J Siliciano RF: Reservoirs for HIV-1: mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy. Annu Rev Immunol 2000, 18:665-708. 10.1146/ annurev.immunol.18.1.665 10837072
    • (2000) Annu Rev Immunol , vol.18 , pp. 665-708
    • Pierson, T.1    McArthur, J.2    Siliciano, R.F.3
  • 42
    • 0032549086 scopus 로고    scopus 로고
    • Rapid turnover of T lymphocytes in SIV-infected rhesus macaques
    • 10.1126/science.279.5354.1223 9469816
    • Mohri H Bonhoeffer S Monard S Perelson AS Ho DD; Rapid turnover of T lymphocytes in SIV-infected rhesus macaques. Science 1998, 279:1223-1227. 10.1126/science.279.5354.1223 9469816
    • (1998) Science , vol.279 , pp. 1223-1227
    • Mohri, H.1    Bonhoeffer, S.2    Monard, S.3    Perelson, A.S.4    Ho, D.D.5
  • 46
    • 0036334097 scopus 로고    scopus 로고
    • Decelerating decay of latently infected cells during prolonged therapy for human immunodeficiency virus type 1 infection
    • 136417 12163616 10.1128/JVI.76.17.8963-8965.2002
    • Muller V Vigueras-Gomez JF Bonhoeffer S: Decelerating decay of latently infected cells during prolonged therapy for human immunodeficiency virus type 1 infection. J Virol 2002, 76:8963-8965. 136417 12163616 10.1128/ JVI.76.17.8963-8965.2002
    • (2002) J Virol , vol.76 , pp. 8963-8965
    • Muller, V.1    Vigueras-Gomez, J.F.2    Bonhoeffer, S.3
  • 48
    • 0035964685 scopus 로고    scopus 로고
    • CD4 T cell expansions are associated with increased apoptosis rates of T lymphocytes during IL-2 cycles in HIV infected patients
    • 10.1097/00002030-200109280-00004 11579237
    • Sereti I Herpin B Metcalf JA Stevens R Baseler MW Hallahan CW Kovacs JA Davey RT: Lane HC CD4 T cell expansions are associated with increased apoptosis rates of T lymphocytes during IL-2 cycles in HIV infected patients. AIDS 2001, 15:1765-1775. 10.1097/00002030-200109280-00004 11579237
    • (2001) AIDS , vol.15 , pp. 1765-1775
    • Sereti, I.1    Herpin, B.2    Metcalf, J.A.3    Stevens, R.4    Baseler, M.W.5    Hallahan, C.W.6    Kovacs, J.A.7    Davey, R.T.8    Lane, H.C.9
  • 54
    • 0036720438 scopus 로고    scopus 로고
    • Persistence of wild-type virus and lack of temporal structure in the latent reservoir for human immunodeficiency virus type 1 in pediatric patients with extensive antiretroviral exposure
    • 136462 12186930 10.1128/JVI.76.18.9481-9492.2002
    • Ruff CT Ray SC Kwon P Zinn R Pendleton A Hutton N Ashworth R Gange S Quinn TC Siliciano RF Persaud DL: Persistence of wild-type virus and lack of temporal structure in the latent reservoir for human immunodeficiency virus type 1 in pediatric patients with extensive antiretroviral exposure. J Virol 2002, 76:9481-9492. 136462 12186930 10.1128/JVI.76.18.9481-9492.2002
    • (2002) J Virol , vol.76 , pp. 9481-9492
    • Ruff, C.T.1    Ray, S.C.2    Kwon, P.3    Zinn, R.4    Pendleton, A.5    Hutton, N.6    Ashworth, R.7    Gange, S.8    Quinn, T.C.9    Siliciano, R.F.10    Persaud, D.11
  • 56
    • 0036571311 scopus 로고    scopus 로고
    • Dynamics of naive and memory CD4+ T lymphocytes in HIV-1 disease progression
    • 10.1097/00126334-200205010-00006 12048362
    • Bajaria SH Webb G Cloyd M Kirschner D: Dynamics of naive and memory CD4+ T lymphocytes in HIV-1 disease progression. J Acquir Immune Defic Syndr 2002, 30:41-58. 10.1097/00126334-200205010-00006 12048362
    • (2002) J Acquir Immune Defic Syndr , vol.30 , pp. 41-58
    • Bajaria, S.H.1    Webb, G.2    Cloyd, M.3    Kirschner, D.4
  • 57
    • 0347951393 scopus 로고    scopus 로고
    • The contribution of monocyte infection and trafficking to viral persistence, and maintenance of the viral reservoir in HIV infection
    • 10.1189/jlb.0503204 12960232
    • Crowe S Zhu T Muller WA: The contribution of monocyte infection and trafficking to viral persistence, and maintenance of the viral reservoir in HIV infection. J Leukoc Biol 2003, 74:635-641. 10.1189/jlb.0503204 12960232
    • (2003) J Leukoc Biol , vol.74 , pp. 635-641
    • Crowe, S.1    Zhu, T.2    Muller, W.A.3
  • 58
    • 0032122490 scopus 로고    scopus 로고
    • Cellular and anatomical reservoirs of HIV-1 in patients receiving potent antiretroviral combination therapy
    • 10.1001/jama.280.1.67 9660366
    • Schrager LK D'Souza MP; Cellular and anatomical reservoirs of HIV-1 in patients receiving potent antiretroviral combination therapy. JAMA 1998, 280:67-71. 10.1001/jama.280.1.67 9660366
    • (1998) JAMA , vol.280 , pp. 67-71
    • Schrager, L.K.1    D'Souza, M.P.2
  • 59
    • 0028952146 scopus 로고
    • HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy
    • 10.1126/science.7824947 7824947
    • Coffin JM: HIV population dInamics in vivo: implications for genetic variation, pathogenesis, and therapy. Science 1995, 267:483-489. 10.1126/ science.7824947 7824947
    • (1995) Science , vol.267 , pp. 483-489
    • Coffin, J.M.1
  • 62
    • 27644454187 scopus 로고    scopus 로고
    • IL-7 as a potential therapy for HIV-1-infected individuals
    • 10.1517/14712598.5.11.1421 16255646
    • Nunnari G Pomerantz RJ; IL-7 as a potential therapy for HIV-1-infected individuals. Expert Opin Biol Ther 2005, 5:1421-1426. 10.1517/ 14712598.5.11.1421 16255646
    • (2005) Expert Opin Biol Ther , vol.5 , pp. 1421-1426
    • Nunnari, G.1    Pomerantz, R.J.2
  • 64
    • 0035892120 scopus 로고    scopus 로고
    • Prostratin: Activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART
    • 10.1182/blood.V98.10.3006 11698284
    • Kulkosky J Culnan DM Roman J Dornadula G Schnell M Boyd MR Pomerantz RJ: Prostratin: Activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART. Blood 2001, 98:3006-3015. 10.1182/ blood.V98.10.3006 11698284
    • (2001) Blood , vol.98 , pp. 3006-3015
    • Kulkosky, J.1    Culnan, D.M.2    Roman, J.3    Dornadula, G.4    Schnell, M.5    Boyd, M.R.6    Pomerantz, R.J.7
  • 65
    • 0036371443 scopus 로고    scopus 로고
    • Modelling viral and immune system dynamics
    • 10.1038/nri700 11905835
    • Perelson AS: Modelling viral and immune system dynamics. Nat Rev Immunol 2002, 2:28-36. 10.1038/nri700 11905835
    • (2002) Nat Rev Immunol , vol.2 , pp. 28-36
    • Perelson, A.S.1
  • 66
    • 0036297271 scopus 로고    scopus 로고
    • Mathematical analysis of delay differential equation models of HIV-1 infection
    • 10.1016/S0025-5564(02)00099-8 12047922
    • Nelson PW Perelson AS: Mathematical analysis of delay differential equation models of HIV-1 infection. Math Biosci 2002, 179:73-94. 10.1016/ S0025-5564(02)00099-8 12047922
    • (2002) Math Biosci , vol.179 , pp. 73-94
    • Nelson, P.W.1    Perelson, A.S.2
  • 67
    • 20444393131 scopus 로고    scopus 로고
    • HIV dynamics with multiple infections of target cells
    • 1149399 15928092 10.1073/pnas.0407498102
    • Dixit NM Perelson AS: HIV dynamics with multiple infections of target cells. Proc Natl Acad Sci USA 2005, 102:8198-8203. 1149399 15928092 10.1073/pnas.0407498102
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8198-8203
    • Dixit, N.M.1    Perelson, A.S.2
  • 70
    • 0028874048 scopus 로고
    • Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
    • 10.1038/373123a0 7816094
    • Ho DD Neumann AU Perelson AS Chen W Leonard JM Markowitz M: Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 1995, 373:123-126. 10.1038/373123a0 7816094
    • (1995) Nature , vol.373 , pp. 123-126
    • Ho, D.D.1    Neumann, A.U.2    Perelson, A.S.3    Chen, W.4    Leonard, J.M.5    Markowitz, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.