메뉴 건너뛰기




Volumn 40, Issue 4, 2008, Pages 565-575

Genetic and epigenetic alterations in breast cancer: What are the perspectives for clinical practice?

Author keywords

Breast cancer; Epigenetic; Genetic; Genomic medicine; Targeted therapy

Indexed keywords

BEVACIZUMAB; CAPECITABINE; TAMOXIFEN;

EID: 39649113846     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2007.10.018     Document Type: Short Survey
Times cited : (25)

References (108)
  • 1
    • 33644825203 scopus 로고    scopus 로고
    • Clinical stage of breast cancer by parity, age at birth, and time since birth: A progressive effect of pregnancy hormones?
    • Albrektsen G., Heuch I., Thoresen S., and Kvale G. Clinical stage of breast cancer by parity, age at birth, and time since birth: A progressive effect of pregnancy hormones?. Cancer Epidemiol. Biomarkers Prev. 13 1 (2006) 65-69
    • (2006) Cancer Epidemiol. Biomarkers Prev. , vol.13 , Issue.1 , pp. 65-69
    • Albrektsen, G.1    Heuch, I.2    Thoresen, S.3    Kvale, G.4
  • 2
    • 33646445514 scopus 로고    scopus 로고
    • Pregnancies, breast-feeding, and breast cancer rosk in the international BRCA1/2 carrier cohort study (BCCS)
    • Andrieu N., Goldgar D.E., Easton D.F., Rookus M., Brohet R., Antoniou A.C., et al. Pregnancies, breast-feeding, and breast cancer rosk in the international BRCA1/2 carrier cohort study (BCCS). J. Natl. Cancer Inst. 98 8 (2006) 535-544
    • (2006) J. Natl. Cancer Inst. , vol.98 , Issue.8 , pp. 535-544
    • Andrieu, N.1    Goldgar, D.E.2    Easton, D.F.3    Rookus, M.4    Brohet, R.5    Antoniou, A.C.6
  • 5
    • 24144475284 scopus 로고    scopus 로고
    • Reversing histone methylation
    • Bannister A.J., and Kouzarides T. Reversing histone methylation. Nature 436 7054 (2005) 1103-1106
    • (2005) Nature , vol.436 , Issue.7054 , pp. 1103-1106
    • Bannister, A.J.1    Kouzarides, T.2
  • 6
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stm cells promote radioresistance by preferential activation of the DNA damage response
    • Bao S., Wu Q., McLendon R.E., Hao Y., Shi Q., Hjelmeland A.B., et al. Glioma stm cells promote radioresistance by preferential activation of the DNA damage response. Nature 444 7120 (2006) 756-760
    • (2006) Nature , vol.444 , Issue.7120 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6
  • 7
    • 0016637886 scopus 로고
    • Intercalating agents as probes of the spatial relationship between chromatin components
    • Baxter C.S., and Byvoet P. Intercalating agents as probes of the spatial relationship between chromatin components. Biochem. Biophys. Res. Commun. 63 1 (1975) 286-291
    • (1975) Biochem. Biophys. Res. Commun. , vol.63 , Issue.1 , pp. 286-291
    • Baxter, C.S.1    Byvoet, P.2
  • 8
    • 33748451151 scopus 로고    scopus 로고
    • Anticancer activites of histone deactylase inhibitors
    • Bolden J.E., Peart M.J., and Johnstone R.W. Anticancer activites of histone deactylase inhibitors. Nat. Rev. Drug Discov. 5 9 (2006) 769-784
    • (2006) Nat. Rev. Drug Discov. , vol.5 , Issue.9 , pp. 769-784
    • Bolden, J.E.1    Peart, M.J.2    Johnstone, R.W.3
  • 10
    • 0347519224 scopus 로고    scopus 로고
    • Evaluation of bone marrow in breast cancer patients: Prediction of clinical outcome and response to therapy
    • Braun S., Vogl F.D., Janni W., Marth C., Schlimok G., and Pantel K. Evaluation of bone marrow in breast cancer patients: Prediction of clinical outcome and response to therapy. Breast 12 6 (2003) 397-404
    • (2003) Breast , vol.12 , Issue.6 , pp. 397-404
    • Braun, S.1    Vogl, F.D.2    Janni, W.3    Marth, C.4    Schlimok, G.5    Pantel, K.6
  • 12
    • 22244435605 scopus 로고    scopus 로고
    • Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferase
    • Brueckner B., Boy R.G., Siedlecki P., Musch T., Kliem H.C., Zielenkiewicz P., et al. Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferase. Cancer Res. 65 14 (2005) 6305-6311
    • (2005) Cancer Res. , vol.65 , Issue.14 , pp. 6305-6311
    • Brueckner, B.1    Boy, R.G.2    Siedlecki, P.3    Musch, T.4    Kliem, H.C.5    Zielenkiewicz, P.6
  • 13
    • 0012689224 scopus 로고    scopus 로고
    • Phase II trial of the anti-VEGF antibody bevacizumab in combination with vinorelbine for refractory advanced breast cancer
    • [abstract 446]
    • Burstein H.J., Parker L.M., and Savoie J. Phase II trial of the anti-VEGF antibody bevacizumab in combination with vinorelbine for refractory advanced breast cancer. Breast Cancer Res. Treat. 76 Suppl. 1 (2002) S115 [abstract 446]
    • (2002) Breast Cancer Res. Treat. , vol.76 , Issue.SUPPL. 1
    • Burstein, H.J.1    Parker, L.M.2    Savoie, J.3
  • 14
    • 0015296118 scopus 로고
    • The distribution and turnover of labeled methyl groups in histone fractions of cultured mammalian cells
    • Byvoet P., Shepherd G.R., Hardin J.M., and Noland B.J. The distribution and turnover of labeled methyl groups in histone fractions of cultured mammalian cells. Arch. Biochem. Biophys. 148 2 (1972) 558-567
    • (1972) Arch. Biochem. Biophys. , vol.148 , Issue.2 , pp. 558-567
    • Byvoet, P.1    Shepherd, G.R.2    Hardin, J.M.3    Noland, B.J.4
  • 15
    • 33746407333 scopus 로고    scopus 로고
    • The emerging science of epigenomics
    • Callinan P.A., and Feinberg A.P. The emerging science of epigenomics. Hum. Mol. Genet. 15 Special issue 1 (2006) R95-R101
    • (2006) Hum. Mol. Genet. , vol.15 , Issue.SPEC. ISSUE 1
    • Callinan, P.A.1    Feinberg, A.P.2
  • 16
    • 0030963564 scopus 로고    scopus 로고
    • Molecular genetic analysis of TGF beta1 in breast cancer
    • Cardillo M.R., Yap E., and Castagna G. Molecular genetic analysis of TGF beta1 in breast cancer. J. Clin. Cancer Res. 16 1 (1997) 57-63
    • (1997) J. Clin. Cancer Res. , vol.16 , Issue.1 , pp. 57-63
    • Cardillo, M.R.1    Yap, E.2    Castagna, G.3
  • 17
    • 33947493624 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 differentially regulates estrogen receptor-dependent transcription at estrogen response element and AP-1 sites in breast cancer cells
    • Cascio S., Bartella V., Garofalo C., Russo A., Giordano A., and Surmacz E. Insulin-like growth factor 1 differentially regulates estrogen receptor-dependent transcription at estrogen response element and AP-1 sites in breast cancer cells. J. Biol. Chem. 282 6 (2007) 3498-3506
    • (2007) J. Biol. Chem. , vol.282 , Issue.6 , pp. 3498-3506
    • Cascio, S.1    Bartella, V.2    Garofalo, C.3    Russo, A.4    Giordano, A.5    Surmacz, E.6
  • 19
    • 39649117864 scopus 로고    scopus 로고
    • Progressive resistance training in beast cancer: A systematic review of clinical trials
    • [epub ahead of print]
    • Cheema B., Gaul C.A., Lane K., and Fiatarone Singh M.A. Progressive resistance training in beast cancer: A systematic review of clinical trials. Breast Cancer Res. Treat. (2007) [epub ahead of print]
    • (2007) Breast Cancer Res. Treat.
    • Cheema, B.1    Gaul, C.A.2    Lane, K.3    Fiatarone Singh, M.A.4
  • 20
    • 34447276477 scopus 로고    scopus 로고
    • Risk factors and hormone-receptor status: Epidemiology, risk-prediction models and treatment implications for breast cancer
    • Chen W.Y., and Colditz G.A. Risk factors and hormone-receptor status: Epidemiology, risk-prediction models and treatment implications for breast cancer. Nat. Clin. Pract. Oncol. 4 7 (2007) 415-423
    • (2007) Nat. Clin. Pract. Oncol. , vol.4 , Issue.7 , pp. 415-423
    • Chen, W.Y.1    Colditz, G.A.2
  • 21
    • 33846011470 scopus 로고    scopus 로고
    • A five-gene signature and clinical outcome in non-small-cell lung cancer
    • Chen H.Y., Yu S.L., Chen C.H., Chang G.C., Chen C.Y., Yuan A., et al. A five-gene signature and clinical outcome in non-small-cell lung cancer. N. Engl. J. Med. 356 1 (2007) 11-20
    • (2007) N. Engl. J. Med. , vol.356 , Issue.1 , pp. 11-20
    • Chen, H.Y.1    Yu, S.L.2    Chen, C.H.3    Chang, G.C.4    Chen, C.Y.5    Yuan, A.6
  • 22
    • 3042623269 scopus 로고    scopus 로고
    • The impact of new chemotherapeutic and hormonal agents on the survival of women with metastatic breast cancer (MBC) in a population based cohort
    • [abstract]
    • Chia S.K.L., Speers C., Kang D., Yachlova Y., Malfair-Taylor S., et al. The impact of new chemotherapeutic and hormonal agents on the survival of women with metastatic breast cancer (MBC) in a population based cohort. Proc. Am. Soc. Clin. Oncol. 22 6 (2003) 22 [abstract]
    • (2003) Proc. Am. Soc. Clin. Oncol. , vol.22 , Issue.6 , pp. 22
    • Chia, S.K.L.1    Speers, C.2    Kang, D.3    Yachlova, Y.4    Malfair-Taylor, S.5
  • 23
    • 0242468884 scopus 로고    scopus 로고
    • A phase I-II dose-escalation trial of bevacizumab in previously treated metastatic breast cancer
    • Cobleigh M.A., Langmuir V.K., Sledge G.W., Miller K.D., Haney L., Novotny W.F., et al. A phase I-II dose-escalation trial of bevacizumab in previously treated metastatic breast cancer. Semin. Oncol. 30 Suppl. 16 (2003) 117-124
    • (2003) Semin. Oncol. , vol.30 , Issue.SUPPL. 16 , pp. 117-124
    • Cobleigh, M.A.1    Langmuir, V.K.2    Sledge, G.W.3    Miller, K.D.4    Haney, L.5    Novotny, W.F.6
  • 24
    • 0037131523 scopus 로고    scopus 로고
    • Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that mraks chromosomal polycomb sites
    • Czermin B., Melfi R., McCabe D., Seitz V., Imhof A., and Pirrotta V. Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that mraks chromosomal polycomb sites. Cell 111 2 (2002) 185-196
    • (2002) Cell , vol.111 , Issue.2 , pp. 185-196
    • Czermin, B.1    Melfi, R.2    McCabe, D.3    Seitz, V.4    Imhof, A.5    Pirrotta, V.6
  • 25
    • 1242316271 scopus 로고    scopus 로고
    • Unique polycomb gene expression pattern in Hodgkin's lymphoma and Hodgkin's lymphoma-derived cell lines
    • Dukers D.F., van Galen J.C., Giroth C., Jansen P., Sewalt R.G., Otte A.P., et al. Unique polycomb gene expression pattern in Hodgkin's lymphoma and Hodgkin's lymphoma-derived cell lines. Am. J. Pathol. 164 7 (2004) 873-881
    • (2004) Am. J. Pathol. , vol.164 , Issue.7 , pp. 873-881
    • Dukers, D.F.1    van Galen, J.C.2    Giroth, C.3    Jansen, P.4    Sewalt, R.G.5    Otte, A.P.6
  • 26
    • 0345275879 scopus 로고    scopus 로고
    • Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
    • Fang M.Z., Wang Y., Ai N., Hou Z., Sun Y., Lu H., et al. Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res. 63 22 (2003) 7563-7570
    • (2003) Cancer Res. , vol.63 , Issue.22 , pp. 7563-7570
    • Fang, M.Z.1    Wang, Y.2    Ai, N.3    Hou, Z.4    Sun, Y.5    Lu, H.6
  • 27
    • 0035163842 scopus 로고    scopus 로고
    • Methylation meets genomics
    • Feinberg A.P. Methylation meets genomics. Nat. Genet. 27 1 (2001) 9-10
    • (2001) Nat. Genet. , vol.27 , Issue.1 , pp. 9-10
    • Feinberg, A.P.1
  • 28
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1 (1995) 27-31
    • (1995) Nat. Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 29
    • 12144290945 scopus 로고    scopus 로고
    • Estrogen receptor status in BRCA1- and BRCA2-related breast cancer: The influence of age, grade, and histological type
    • Foulkes W.D., Metcalfe K., Sun P., Hanna W.M., Lynch H.T., Ghadirian P., et al. Estrogen receptor status in BRCA1- and BRCA2-related breast cancer: The influence of age, grade, and histological type. Clin. Cancer Res. 10 (2004) 2029-2034
    • (2004) Clin. Cancer Res. , vol.10 , pp. 2029-2034
    • Foulkes, W.D.1    Metcalfe, K.2    Sun, P.3    Hanna, W.M.4    Lynch, H.T.5    Ghadirian, P.6
  • 31
    • 34347263739 scopus 로고    scopus 로고
    • Carcinogenesis and environment: The cancer stem cell hypothesis and implications for the development of novel therapeutics and diagnostics
    • Giordano A., Fucito A., Romano G., and Marino I.R. Carcinogenesis and environment: The cancer stem cell hypothesis and implications for the development of novel therapeutics and diagnostics. Front. Biosci. 12 (2007) 3475-3482
    • (2007) Front. Biosci. , vol.12 , pp. 3475-3482
    • Giordano, A.1    Fucito, A.2    Romano, G.3    Marino, I.R.4
  • 32
    • 34848898446 scopus 로고    scopus 로고
    • Tumor suppressor pRb2/p130 gene and its derived product Spa310 spacer domain as perspective candidates for cancer therapy
    • Giordano A., Rossi A., Romano G., and Bagella L. Tumor suppressor pRb2/p130 gene and its derived product Spa310 spacer domain as perspective candidates for cancer therapy. J. Cell. Physiol. 213 2 (2007) 403-406
    • (2007) J. Cell. Physiol. , vol.213 , Issue.2 , pp. 403-406
    • Giordano, A.1    Rossi, A.2    Romano, G.3    Bagella, L.4
  • 33
    • 20444457518 scopus 로고    scopus 로고
    • Micorarray analysis reveals a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
    • Glinsky G.V., Berezovska O., and Glinskii A.B. Micorarray analysis reveals a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. J. Clin. Invest. 115 6 (2005) 1503-1521
    • (2005) J. Clin. Invest. , vol.115 , Issue.6 , pp. 1503-1521
    • Glinsky, G.V.1    Berezovska, O.2    Glinskii, A.B.3
  • 34
    • 0035253739 scopus 로고    scopus 로고
    • Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer
    • Gordon M.S., Margolin K., Talpaz M., Sledge Jr. G.W., Holmgren E., Benjamin R., et al. Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer. J. Clin. Oncol. 19 (2001) 840-843
    • (2001) J. Clin. Oncol. , vol.19 , pp. 840-843
    • Gordon, M.S.1    Margolin, K.2    Talpaz, M.3    Sledge Jr., G.W.4    Holmgren, E.5    Benjamin, R.6
  • 35
    • 33846537292 scopus 로고    scopus 로고
    • HPV DNA frequency and subset in human breast cancer patients' normal and tumoral tissue samples
    • Gumus M., Yumuk P.F., Salepci T., Allustaoglu M., Dane F., Ekenel M., et al. HPV DNA frequency and subset in human breast cancer patients' normal and tumoral tissue samples. J. Exp. Clin. Cancer Res. 25 4 (2006) 515-521
    • (2006) J. Exp. Clin. Cancer Res. , vol.25 , Issue.4 , pp. 515-521
    • Gumus, M.1    Yumuk, P.F.2    Salepci, T.3    Allustaoglu, M.4    Dane, F.5    Ekenel, M.6
  • 36
    • 0037038224 scopus 로고    scopus 로고
    • Genomic medicine-A primer
    • Guttmacher A.E., and Collins F.S. Genomic medicine-A primer. N. Engl. J. Med. 347 19 (2002) 1512-1520
    • (2002) N. Engl. J. Med. , vol.347 , Issue.19 , pp. 1512-1520
    • Guttmacher, A.E.1    Collins, F.S.2
  • 38
    • 33846031169 scopus 로고    scopus 로고
    • Molecular signatures of lung cancer-Toward personalized therapy
    • Herbst R.S., and Lippman S.M. Molecular signatures of lung cancer-Toward personalized therapy. N. Engl. J. Med. 356 1 (2007) 76-78
    • (2007) N. Engl. J. Med. , vol.356 , Issue.1 , pp. 76-78
    • Herbst, R.S.1    Lippman, S.M.2
  • 39
    • 0034724870 scopus 로고    scopus 로고
    • The accessibility of histone H3 tails in chromatin modulates their acetylation by P300/CBP-associated factor
    • Herrera J.E., Schiltz R.L., and Bustin M. The accessibility of histone H3 tails in chromatin modulates their acetylation by P300/CBP-associated factor. J. Biol. Chem. 275 17 (2000) 12994-12999
    • (2000) J. Biol. Chem. , vol.275 , Issue.17 , pp. 12994-12999
    • Herrera, J.E.1    Schiltz, R.L.2    Bustin, M.3
  • 40
    • 0033975839 scopus 로고    scopus 로고
    • Histone H1 is a specific repressor of core histone acetylation in chromatin
    • Herrera J.E., West K.L., Schiltz R.L., Nakatani Y., and Bustin M. Histone H1 is a specific repressor of core histone acetylation in chromatin. Mol. Cell. Biol. 20 2 (2000) 523-529
    • (2000) Mol. Cell. Biol. , vol.20 , Issue.2 , pp. 523-529
    • Herrera, J.E.1    West, K.L.2    Schiltz, R.L.3    Nakatani, Y.4    Bustin, M.5
  • 41
    • 13444291201 scopus 로고    scopus 로고
    • Inhibitors of VEGF receptors significantly impairs mammary cancer growth in C3(1)/Tag transgenic mice through antiangiogenic and non-antiangiogenic mechanisms
    • Huh J.I., Calvo A., Stafford J., Cheung M., Kaman R., Philip D., et al. Inhibitors of VEGF receptors significantly impairs mammary cancer growth in C3(1)/Tag transgenic mice through antiangiogenic and non-antiangiogenic mechanisms. Oncogene 24 (2005) 790-800
    • (2005) Oncogene , vol.24 , pp. 790-800
    • Huh, J.I.1    Calvo, A.2    Stafford, J.3    Cheung, M.4    Kaman, R.5    Philip, D.6
  • 42
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • Hynes N.E., and Lane H.A. ERBB receptors and cancer: The complexity of targeted inhibitors. Nat. Rev. Cancer 5 (2005) 341-354
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 43
    • 33747855481 scopus 로고    scopus 로고
    • Comparing antibody and small molecule therapy for cancer
    • Imay K., and Tanaka A. Comparing antibody and small molecule therapy for cancer. Nat. Rev. Cancer 6 (2006) 714-727
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 714-727
    • Imay, K.1    Tanaka, A.2
  • 45
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones P.A., and Baylin S.B. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3 (2002) 415-428
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 46
    • 31344472398 scopus 로고    scopus 로고
    • Genetic model of human cancer as a multistep process, paradigm models of colorectal cancer, breast cancer, and chronic myelogenous and acute lymphoblastic leukemia
    • Karakosta A., Golias C., Charalabopoulos A., Peschos D., Batistatou A., and Charalabopoulos K. Genetic model of human cancer as a multistep process, paradigm models of colorectal cancer, breast cancer, and chronic myelogenous and acute lymphoblastic leukemia. J. Exp. Clin. Cancer Res. 24 4 (2005) 505-514
    • (2005) J. Exp. Clin. Cancer Res. , vol.24 , Issue.4 , pp. 505-514
    • Karakosta, A.1    Golias, C.2    Charalabopoulos, A.3    Peschos, D.4    Batistatou, A.5    Charalabopoulos, K.6
  • 47
    • 0030710153 scopus 로고    scopus 로고
    • How does DNA methylation repress transcription?
    • Kass S.U., Pruss D., and Wolffe A.P. How does DNA methylation repress transcription?. Trends Genet. 13 11 (1997) 444-449
    • (1997) Trends Genet. , vol.13 , Issue.11 , pp. 444-449
    • Kass, S.U.1    Pruss, D.2    Wolffe, A.P.3
  • 48
    • 34547866682 scopus 로고    scopus 로고
    • Targeting EGFR and HER-2 with cetuximab and trastuzumab-mediated immunotherapy in oesophageal squamous cell carcinoma
    • [epub ahead of print]
    • Kawaguchi Y., Kono K., Mimura K., Mitsui F., Sugai H., Akaike H., et al. Targeting EGFR and HER-2 with cetuximab and trastuzumab-mediated immunotherapy in oesophageal squamous cell carcinoma. Br. J. Cancer (2007) [epub ahead of print]
    • (2007) Br. J. Cancer
    • Kawaguchi, Y.1    Kono, K.2    Mimura, K.3    Mitsui, F.4    Sugai, H.5    Akaike, H.6
  • 49
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo
    • Kim K.J., Li B., Winer J., Armanini M., Gillet N., Phillips H.S., et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo. Nature 362 (1993) 841-844
    • (1993) Nature , vol.362 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3    Armanini, M.4    Gillet, N.5    Phillips, H.S.6
  • 50
    • 33750030758 scopus 로고    scopus 로고
    • The regulation of INK4/ARF in cancer and aging
    • Kim W.Y., and Sharpless N.E. The regulation of INK4/ARF in cancer and aging. Cell 127 2 (2006) 265-275
    • (2006) Cell , vol.127 , Issue.2 , pp. 265-275
    • Kim, W.Y.1    Sharpless, N.E.2
  • 51
    • 0141816752 scopus 로고    scopus 로고
    • EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
    • Kleer C.G., Cao Q., Varambally S., Shen R., Ota I., Tomlins S.A., et al. EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proc. Natl. Acad. Sci. U.S.A. 100 20 (2003) 11606-11611
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , Issue.20 , pp. 11606-11611
    • Kleer, C.G.1    Cao, Q.2    Varambally, S.3    Shen, R.4    Ota, I.5    Tomlins, S.A.6
  • 52
    • 0036767059 scopus 로고    scopus 로고
    • High-risk screening: Multi-modality surveillance of women at high risk for breast cancer (proven or suspected carriers of a breast cancer susceptibility gene)
    • Kuhl C.K. High-risk screening: Multi-modality surveillance of women at high risk for breast cancer (proven or suspected carriers of a breast cancer susceptibility gene). J. Exp. Clin. Cancer Res. 21 Suppl. 3 (2002) 103-106
    • (2002) J. Exp. Clin. Cancer Res. , vol.21 , Issue.SUPPL. 3 , pp. 103-106
    • Kuhl, C.K.1
  • 53
    • 0037111831 scopus 로고    scopus 로고
    • Histone methyltransferase activity associated with a human multiprotein complex containing the enhancer of Zeste protein
    • Kuzmichev A., Nishioka K., Erdjument-Bromage H., Tempst P., and Reinberg D. Histone methyltransferase activity associated with a human multiprotein complex containing the enhancer of Zeste protein. Genes Dev. 16 22 (2002) 2893-2905
    • (2002) Genes Dev. , vol.16 , Issue.22 , pp. 2893-2905
    • Kuzmichev, A.1    Nishioka, K.2    Erdjument-Bromage, H.3    Tempst, P.4    Reinberg, D.5
  • 55
    • 0027465862 scopus 로고
    • A positive role for histone acetylation in transcription factor access to nucleosomal DNA
    • Lee D.Y., Hayes J.J., Pruss D., and Wolffe A.P. A positive role for histone acetylation in transcription factor access to nucleosomal DNA. Cell 72 1 (1993) 73-84
    • (1993) Cell , vol.72 , Issue.1 , pp. 73-84
    • Lee, D.Y.1    Hayes, J.J.2    Pruss, D.3    Wolffe, A.P.4
  • 56
    • 0035341465 scopus 로고    scopus 로고
    • Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci
    • Litt M.D., Simpson M., Recillas-Targa F., Prioleau M.N., and Felsenfeld G. Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci. EMBO J. 20 9 (2001) 2224-2235
    • (2001) EMBO J. , vol.20 , Issue.9 , pp. 2224-2235
    • Litt, M.D.1    Simpson, M.2    Recillas-Targa, F.3    Prioleau, M.N.4    Felsenfeld, G.5
  • 57
    • 33846425793 scopus 로고    scopus 로고
    • The prognostic role of a gene signature from tumorigenic breast-cancer cells
    • Liu R., Wang X., Chen G.Y., Dalerba P., Gurney A., Hoey T., et al. The prognostic role of a gene signature from tumorigenic breast-cancer cells. N. Engl. J. Med. 356 3 (2007) 217-226
    • (2007) N. Engl. J. Med. , vol.356 , Issue.3 , pp. 217-226
    • Liu, R.1    Wang, X.2    Chen, G.Y.3    Dalerba, P.4    Gurney, A.5    Hoey, T.6
  • 58
    • 33644625997 scopus 로고    scopus 로고
    • Dynamic nucleosomes
    • Luger K. Dynamic nucleosomes. Chromosome Res. 14 (2006) 5-16
    • (2006) Chromosome Res. , vol.14 , pp. 5-16
    • Luger, K.1
  • 59
    • 0038304456 scopus 로고    scopus 로고
    • pRb2/p130-E2F4/5-HDAC1-SUV39H1-p300 and pRb2/p130-E2F4/5-HDAC1-SUV39H1-DNMT1 multimolecular complexes mediate the transcription of estrogen receptor-α in breast cancer
    • Macaluso M., Cinti C., Russo G., Russo A., and Giordano A. pRb2/p130-E2F4/5-HDAC1-SUV39H1-p300 and pRb2/p130-E2F4/5-HDAC1-SUV39H1-DNMT1 multimolecular complexes mediate the transcription of estrogen receptor-α in breast cancer. Oncogene 22 23 (2003) 3511-3517
    • (2003) Oncogene , vol.22 , Issue.23 , pp. 3511-3517
    • Macaluso, M.1    Cinti, C.2    Russo, G.3    Russo, A.4    Giordano, A.5
  • 60
    • 33748084700 scopus 로고    scopus 로고
    • Rb family proteins as modulators of gene expression and new aspects regarding the interactions with chromatin remodeling enzymes
    • Macaluso M., Montanari M., and Giordano A. Rb family proteins as modulators of gene expression and new aspects regarding the interactions with chromatin remodeling enzymes. Oncogene 25 38 (2006) 5263-5267
    • (2006) Oncogene , vol.25 , Issue.38 , pp. 5263-5267
    • Macaluso, M.1    Montanari, M.2    Giordano, A.3
  • 61
    • 34548013072 scopus 로고    scopus 로고
    • Epigenetic modulation of estrogen receptor-α by pRb family proteins: A novel mechanism in breast cancer
    • Macaluso M., Montanari M., Noto P.B., Gregorio V., Bronner C., and Giordano A. Epigenetic modulation of estrogen receptor-α by pRb family proteins: A novel mechanism in breast cancer. Cancer Res. 67 16 (2007) 7731-7737
    • (2007) Cancer Res. , vol.67 , Issue.16 , pp. 7731-7737
    • Macaluso, M.1    Montanari, M.2    Noto, P.B.3    Gregorio, V.4    Bronner, C.5    Giordano, A.6
  • 62
    • 0242539832 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations as hallmarks of the intricate road to cancer
    • Macaluso M., Paggi M., and Giordano A. Genetic and epigenetic alterations as hallmarks of the intricate road to cancer. Oncogene 22 42 (2003) 6472-6478
    • (2003) Oncogene , vol.22 , Issue.42 , pp. 6472-6478
    • Macaluso, M.1    Paggi, M.2    Giordano, A.3
  • 63
    • 0035253586 scopus 로고    scopus 로고
    • Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chremotherapy in patients with advanced cancer: Pharmacologic and long-term safety data
    • Margolin K., Gordon M.S., Holigren E., Gandreault J., Novotny W., Fyfe G., et al. Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chremotherapy in patients with advanced cancer: Pharmacologic and long-term safety data. J. Clin. Oncol. 19 (2001) 851-856
    • (2001) J. Clin. Oncol. , vol.19 , pp. 851-856
    • Margolin, K.1    Gordon, M.S.2    Holigren, E.3    Gandreault, J.4    Novotny, W.5    Fyfe, G.6
  • 64
    • 0025243605 scopus 로고
    • Isolation and characterization of acetylated histones H3 and H4 and their assembly into nucleosomes
    • Marvin K.W., Yau P., and Bradbury E.M. Isolation and characterization of acetylated histones H3 and H4 and their assembly into nucleosomes. J. Biol. Chem. 265 32 (1990) 19839-19847
    • (1990) J. Biol. Chem. , vol.265 , Issue.32 , pp. 19839-19847
    • Marvin, K.W.1    Yau, P.2    Bradbury, E.M.3
  • 66
    • 34250800233 scopus 로고    scopus 로고
    • Breast cancer and ethnicity: Strong association between reproductive risk factors and estrogen receptor status in Asian patients-A retrospective study
    • Menes T.S., Ozao J., and Kim U. Breast cancer and ethnicity: Strong association between reproductive risk factors and estrogen receptor status in Asian patients-A retrospective study. Breast J. 13 4 (2007) 352-358
    • (2007) Breast J. , vol.13 , Issue.4 , pp. 352-358
    • Menes, T.S.1    Ozao, J.2    Kim, U.3
  • 67
    • 0037303885 scopus 로고    scopus 로고
    • E2100: A phase III trial of paclitaxel versus paclitael/bevacizumab for metastatic breast cancer
    • Miller K.D. E2100: A phase III trial of paclitaxel versus paclitael/bevacizumab for metastatic breast cancer. Clin. Breast Cancer 3 (2003) 421-422
    • (2003) Clin. Breast Cancer , vol.3 , pp. 421-422
    • Miller, K.D.1
  • 68
    • 25844465921 scopus 로고    scopus 로고
    • Epigenetic therapy of cancer with 5-aza-2′-deoxycytidine (decitabine)
    • Momparler R.L. Epigenetic therapy of cancer with 5-aza-2′-deoxycytidine (decitabine). Senim. Oncol. 42 3 Suppl. 2 (2005) S9-S16
    • (2005) Senim. Oncol. , vol.42 , Issue.3 SUPPL. 2
    • Momparler, R.L.1
  • 69
    • 34247116336 scopus 로고    scopus 로고
    • Connections between epigenetic gene silencing and human disease
    • Moss T.J., and Wallrath L.L. Connections between epigenetic gene silencing and human disease. Mutat. Res. 618 1/2 (2007) 163-174
    • (2007) Mutat. Res. , vol.618 , Issue.1-2 , pp. 163-174
    • Moss, T.J.1    Wallrath, L.L.2
  • 71
    • 0015912073 scopus 로고
    • Enzymatic demethylation of calf thymus histones
    • Paik W.K., and Kim S. Enzymatic demethylation of calf thymus histones. Biochem. Biophys. Res. Commun. 51 3 (1973) 781-788
    • (1973) Biochem. Biophys. Res. Commun. , vol.51 , Issue.3 , pp. 781-788
    • Paik, W.K.1    Kim, S.2
  • 72
    • 33750693058 scopus 로고    scopus 로고
    • Structure and function of nucleosome assembly proteins
    • Park Y.J., and Luger K. Structure and function of nucleosome assembly proteins. Biochem. Cell. Biol. 84 4 (2006) 549-558
    • (2006) Biochem. Cell. Biol. , vol.84 , Issue.4 , pp. 549-558
    • Park, Y.J.1    Luger, K.2
  • 73
    • 0038349957 scopus 로고    scopus 로고
    • Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
    • Park I.K., Qian D., Kiel M., Becker M.W., Pihalja M., Weissman I.L., et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 423 6937 (2003) 302-305
    • (2003) Nature , vol.423 , Issue.6937 , pp. 302-305
    • Park, I.K.1    Qian, D.2    Kiel, M.3    Becker, M.W.4    Pihalja, M.5    Weissman, I.L.6
  • 74
    • 3042702970 scopus 로고    scopus 로고
    • Polycomb group proteins in cell cycle progression and cancer
    • Pasini D., Bracken A.P., and Helin K. Polycomb group proteins in cell cycle progression and cancer. Cell Cycle 3 4 (2004) 396-400
    • (2004) Cell Cycle , vol.3 , Issue.4 , pp. 396-400
    • Pasini, D.1    Bracken, A.P.2    Helin, K.3
  • 75
    • 9144226103 scopus 로고    scopus 로고
    • Poorly differentiated breast carcinoma is associated with increased expression of the human polycomb group EZH2 gene
    • Raaphorst F.M., Meijer C.J., Fieret E., Blokzijl T., Mommers E., Buerger H., et al. Poorly differentiated breast carcinoma is associated with increased expression of the human polycomb group EZH2 gene. Neoplasia 5 6 (2003) 481-488
    • (2003) Neoplasia , vol.5 , Issue.6 , pp. 481-488
    • Raaphorst, F.M.1    Meijer, C.J.2    Fieret, E.3    Blokzijl, T.4    Mommers, E.5    Buerger, H.6
  • 76
    • 0036767376 scopus 로고    scopus 로고
    • Mutations of BRCA genes in hereditary breast and ovarian cancers
    • Radice P. Mutations of BRCA genes in hereditary breast and ovarian cancers. J. Exp. Clin. Cancer Res. 21 Suppl. 3 (2002) 9-12
    • (2002) J. Exp. Clin. Cancer Res. , vol.21 , Issue.SUPPL. 3 , pp. 9-12
    • Radice, P.1
  • 78
    • 0035370439 scopus 로고    scopus 로고
    • Histone methylation versus histone acetylation: New insights into epigenetic regulation
    • Rice J.C., and Allis C.D. Histone methylation versus histone acetylation: New insights into epigenetic regulation. Curr. Opin. Cell. Biol. 13 3 (2001) 263-273
    • (2001) Curr. Opin. Cell. Biol. , vol.13 , Issue.3 , pp. 263-273
    • Rice, J.C.1    Allis, C.D.2
  • 79
    • 0344013487 scopus 로고    scopus 로고
    • The complex biology of the receptor for the insulin-like growth factor-1
    • Romano G. The complex biology of the receptor for the insulin-like growth factor-1. Drug News Perspect. 16 8 (2003) 525-531
    • (2003) Drug News Perspect. , vol.16 , Issue.8 , pp. 525-531
    • Romano, G.1
  • 80
    • 32844465160 scopus 로고    scopus 로고
    • The role of adult stem cells in carcinogenesis
    • Romano G. The role of adult stem cells in carcinogenesis. Drug News Perspect. 18 9 (2005) 555-559
    • (2005) Drug News Perspect. , vol.18 , Issue.9 , pp. 555-559
    • Romano, G.1
  • 81
    • 0033974016 scopus 로고    scopus 로고
    • Latest development in gene transfer technology: Achievements, perspectives, and controversies over therapeutic applications
    • Romano G., Micheli P., Pacilio C., and Giordano A. Latest development in gene transfer technology: Achievements, perspectives, and controversies over therapeutic applications. Stem Cells 18 1 (2000) 19-39
    • (2000) Stem Cells , vol.18 , Issue.1 , pp. 19-39
    • Romano, G.1    Micheli, P.2    Pacilio, C.3    Giordano, A.4
  • 82
    • 35348971357 scopus 로고    scopus 로고
    • BRCA1 genetic testing in 106 breast and ovarian cancer families from southern Italy (Sicily): A mutational analyses
    • [epub ahead of print]
    • Russo A., Calo V., Agnese V., Bruno I., Corsale S., Augello C., et al. BRCA1 genetic testing in 106 breast and ovarian cancer families from southern Italy (Sicily): A mutational analyses. Breast Cancer Res. Treat. (2007) [epub ahead of print]
    • (2007) Breast Cancer Res. Treat.
    • Russo, A.1    Calo, V.2    Agnese, V.3    Bruno, I.4    Corsale, S.5    Augello, C.6
  • 83
    • 2642542643 scopus 로고    scopus 로고
    • A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
    • Schotta G., Lachner M., Sarma K., Ebert A., Sengupta R., Reader G., et al. A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev. 18 11 (2004) 1251-1262
    • (2004) Genes Dev. , vol.18 , Issue.11 , pp. 1251-1262
    • Schotta, G.1    Lachner, M.2    Sarma, K.3    Ebert, A.4    Sengupta, R.5    Reader, G.6
  • 84
    • 34250748512 scopus 로고    scopus 로고
    • The association between breastfeeding and breast cancer occurrence among Israeli Jewish women: A case control study
    • Shema L., Ore L., Ben-Shakar M., Hai M., and Linn S. The association between breastfeeding and breast cancer occurrence among Israeli Jewish women: A case control study. J. Cancer Res, Oncol. 133 8 (2007) 539-546
    • (2007) J. Cancer Res, Oncol. , vol.133 , Issue.8 , pp. 539-546
    • Shema, L.1    Ore, L.2    Ben-Shakar, M.3    Hai, M.4    Linn, S.5
  • 85
    • 11144332565 scopus 로고    scopus 로고
    • Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
    • Shi Y., Lan F., Matson C., Mulligan P., Whetstine J.R., Cole P.A., et al. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119 7 (2004) 941-953
    • (2004) Cell , vol.119 , Issue.7 , pp. 941-953
    • Shi, Y.1    Lan, F.2    Matson, C.3    Mulligan, P.4    Whetstine, J.R.5    Cole, P.A.6
  • 86
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu proto-oncogene
    • Siamon D.J., Clark G.M., Wong S.G., Levin W.J., Ullrich A., and McGuire. Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu proto-oncogene. Science 235 (1987) 177-182
    • (1987) Science , vol.235 , pp. 177-182
    • Siamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire6
  • 87
    • 0035869407 scopus 로고
    • Use of chemotherapy plus a monocloncal antibody against HER2 for metastatic breast cancer that overexpresses HER-2
    • Siamon D.J., Godolphin W., Jones L.A., Holt J.A., Wong S.G., Keith D.E., et al. Use of chemotherapy plus a monocloncal antibody against HER2 for metastatic breast cancer that overexpresses HER-2. N. Engl. J. Med. 344 (1989) 783-792
    • (1989) N. Engl. J. Med. , vol.344 , pp. 783-792
    • Siamon, D.J.1    Godolphin, W.2    Jones, L.A.3    Holt, J.A.4    Wong, S.G.5    Keith, D.E.6
  • 88
    • 34347375106 scopus 로고    scopus 로고
    • Epigenetic drugs as pleiotropic agents in cancer treatment: Biomolecular aspects and clinical applications
    • Sigalotti L., Fratta E., Coral S., Cortini E., Covre A., Nicolay H.J.M., et al. Epigenetic drugs as pleiotropic agents in cancer treatment: Biomolecular aspects and clinical applications. J. Cell. Physiol. 212 2 (2007) 330-344
    • (2007) J. Cell. Physiol. , vol.212 , Issue.2 , pp. 330-344
    • Sigalotti, L.1    Fratta, E.2    Coral, S.3    Cortini, E.4    Covre, A.5    Nicolay, H.J.M.6
  • 89
    • 34547099311 scopus 로고    scopus 로고
    • Acetylated histone tail peptides induce structural rearrangements in the RSC chromatin remodeling complex
    • Skiniotis G., Moazed D., and Waltz T. Acetylated histone tail peptides induce structural rearrangements in the RSC chromatin remodeling complex. J. Biol. Chem. 282 29 (2007) 20804-20808
    • (2007) J. Biol. Chem. , vol.282 , Issue.29 , pp. 20804-20808
    • Skiniotis, G.1    Moazed, D.2    Waltz, T.3
  • 91
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • Sparmann A., and van Lohuizen M. Polycomb silencers control cell fate, development and cancer. Nat. Rev. Cancer 6 11 (2006) 846-856
    • (2006) Nat. Rev. Cancer , vol.6 , Issue.11 , pp. 846-856
    • Sparmann, A.1    van Lohuizen, M.2
  • 92
    • 0035962649 scopus 로고    scopus 로고
    • Role of protein methylation in chromatin remodeling and transcriptional regulation
    • Stallcup M.R. Role of protein methylation in chromatin remodeling and transcriptional regulation. Oncogene 20 24 (2001) 3014-3020
    • (2001) Oncogene , vol.20 , Issue.24 , pp. 3014-3020
    • Stallcup, M.R.1
  • 93
    • 15044350409 scopus 로고    scopus 로고
    • Relationship between histone H3 lysine 9 methylation, transcription repression, and heterochromatin protein 1 recruitment
    • Stewart M.D., Li J., and Wong J. Relationship between histone H3 lysine 9 methylation, transcription repression, and heterochromatin protein 1 recruitment. Mol. Cell. Biol. 25 7 (2005) 2525-2538
    • (2005) Mol. Cell. Biol. , vol.25 , Issue.7 , pp. 2525-2538
    • Stewart, M.D.1    Li, J.2    Wong, J.3
  • 94
    • 4644319204 scopus 로고    scopus 로고
    • Stem cells and cancer: The polycomb connection
    • Valk-Lingbeek M.E., Bruggeman S.W.M., and van Louizen M. Stem cells and cancer: The polycomb connection. Cell 118 4 (2004) 409-418
    • (2004) Cell , vol.118 , Issue.4 , pp. 409-418
    • Valk-Lingbeek, M.E.1    Bruggeman, S.W.M.2    van Louizen, M.3
  • 95
    • 0037038230 scopus 로고    scopus 로고
    • Getting ready for gene-based medicine
    • Varmus H. Getting ready for gene-based medicine. N. Engl. J. Med. 347 19 (2002) 1526-1527
    • (2002) N. Engl. J. Med. , vol.347 , Issue.19 , pp. 1526-1527
    • Varmus, H.1
  • 96
    • 0041939756 scopus 로고    scopus 로고
    • Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells
    • Villar-Garea A., Fraga M.F., Espada J., and Esteller M. Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res. 63 16 (2003) 4984-4989
    • (2003) Cancer Res. , vol.63 , Issue.16 , pp. 4984-4989
    • Villar-Garea, A.1    Fraga, M.F.2    Espada, J.3    Esteller, M.4
  • 97
    • 33646348204 scopus 로고    scopus 로고
    • Have we found the ultimate risk factor for breast cancer?
    • Vogel V.G., and Taioli E. Have we found the ultimate risk factor for breast cancer?. J. Clin. Oncol. 24 12 (2006) 1791-1794
    • (2006) J. Clin. Oncol. , vol.24 , Issue.12 , pp. 1791-1794
    • Vogel, V.G.1    Taioli, E.2
  • 98
    • 0030940298 scopus 로고    scopus 로고
    • Histone acetylation: Chromatin in action
    • Wade P.A., Pruss D., and Wolffe A.P. Histone acetylation: Chromatin in action. Trends Biochem. Sci. 22 4 (1997) 128-132
    • (1997) Trends Biochem. Sci. , vol.22 , Issue.4 , pp. 128-132
    • Wade, P.A.1    Pruss, D.2    Wolffe, A.P.3
  • 99
    • 0021750061 scopus 로고
    • Differential dissociation of histone tails from core chromatin
    • Walker I.O. Differential dissociation of histone tails from core chromatin. Biochemistry 23 23 (1984) 5622-5628
    • (1984) Biochemistry , vol.23 , Issue.23 , pp. 5622-5628
    • Walker, I.O.1
  • 100
    • 33846850422 scopus 로고    scopus 로고
    • Ten genes for inherited breast cancer
    • Walsh T., and King M.C. Ten genes for inherited breast cancer. Cancer Cell 11 2 (2007) 103-105
    • (2007) Cancer Cell , vol.11 , Issue.2 , pp. 103-105
    • Walsh, T.1    King, M.C.2
  • 101
    • 0034634558 scopus 로고    scopus 로고
    • Acetylation increases the alpha-helical content of the histone tails of the nucleosome
    • Wang X., Moore S.C., Laszckzak M., and Ausio J. Acetylation increases the alpha-helical content of the histone tails of the nucleosome. J. Biol. Chem. 275 45 (2000) 35013-35020
    • (2000) J. Biol. Chem. , vol.275 , Issue.45 , pp. 35013-35020
    • Wang, X.1    Moore, S.C.2    Laszckzak, M.3    Ausio, J.4
  • 102
    • 0034142268 scopus 로고    scopus 로고
    • Insights into the functions of BRCA1 and BRCA2
    • Welcsh P.L., Owens K.N., and King M.C. Insights into the functions of BRCA1 and BRCA2. Trends Genet. 16 2 (2000) 69-74
    • (2000) Trends Genet. , vol.16 , Issue.2 , pp. 69-74
    • Welcsh, P.L.1    Owens, K.N.2    King, M.C.3
  • 103
    • 33644560281 scopus 로고    scopus 로고
    • Cancer stem cells: An old idea-A paradigm shift
    • Wicha M.S., Lin S., and Dontu G. Cancer stem cells: An old idea-A paradigm shift. Cancer Res. 66 4 (2006) 1883-1890
    • (2006) Cancer Res. , vol.66 , Issue.4 , pp. 1883-1890
    • Wicha, M.S.1    Lin, S.2    Dontu, G.3
  • 105
    • 34547864236 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Molecular mechanisms of action
    • Xu W.S., Parmigiani R.B., and Marks P.A. Histone deacetylase inhibitors: Molecular mechanisms of action. Oncogene 26 37 (2007) 5541-5552
    • (2007) Oncogene , vol.26 , Issue.37 , pp. 5541-5552
    • Xu, W.S.1    Parmigiani, R.B.2    Marks, P.A.3
  • 106
    • 33646376411 scopus 로고    scopus 로고
    • Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
    • Yilmaz O.H., Valdez R., Theisen B.K., Guo W., Ferguson D.O., Wu H., et al. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441 7092 (2006) 475-482
    • (2006) Nature , vol.441 , Issue.7092 , pp. 475-482
    • Yilmaz, O.H.1    Valdez, R.2    Theisen, B.K.3    Guo, W.4    Ferguson, D.O.5    Wu, H.6
  • 107
    • 33644856123 scopus 로고    scopus 로고
    • Epigenetic therapy of cancer: Past, present and future
    • Yoo C.B., and Jones P.A. Epigenetic therapy of cancer: Past, present and future. Nat. Rev. Drug Discov. 5 1 (2006) 37-50
    • (2006) Nat. Rev. Drug Discov. , vol.5 , Issue.1 , pp. 37-50
    • Yoo, C.B.1    Jones, P.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.