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Volumn 12, Issue 9, 2007, Pages 3475-3482

Carcinogenesis and environment: The cancer stem cell hypothesis and implications for the development of novel therapeutics and diagnostics

Author keywords

Cancer; Carcinogenesis; Differentiation; Neoplasia; Review; Self renewal; Stem cells; Transformation; Tumor

Indexed keywords

CELL TRANSFORMATION; CYTOLOGY; HUMAN; NEOPLASM; PATHOLOGY; REVIEW; STEM CELL;

EID: 34347263739     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/2328     Document Type: Article
Times cited : (32)

References (67)
  • 1
    • 13844280894 scopus 로고    scopus 로고
    • Oct4 expression in adult human stem cells: Evidence in support of the stem cell theory of carcinogenesis
    • DOI 10.1093/carcin/bgh321
    • Tai, M. H., C. C. Chang, M. Kiupel, J. D. Webster, L. K. Olson, and J. E. Trosko. Oct4 expression in adult human cells: evidence in support of the stem cell theory of carcinogenesis. Carcinogenesis 2:495-502, (2005) (Pubitemid 40246573)
    • (2005) Carcinogenesis , vol.26 , Issue.2 , pp. 495-502
    • Tai, M.-H.1    Chang, C.-C.2    Olson, L.K.3    Trosko, J.E.4
  • 6
    • 33644560281 scopus 로고    scopus 로고
    • Cancer stem cells: An old idea-a paradigm shift
    • Wicha, M. S., S. Liu, and G. Dontu. Cancer stem cells: an old idea-a paradigm shift. Cancer Res 66:1883-1890, (2006)
    • (2006) Cancer Res , vol.66 , pp. 1883-1890
    • Wicha, M.S.1    Liu, S.2    Dontu, G.3
  • 7
    • 3042525924 scopus 로고    scopus 로고
    • Breast cancer, stem/progenitor cells and the estrogen receptor
    • DOI 10.1016/j.tem.2004.05.011, PII S1043276004000955
    • Dontu, G., D. El-Ashry, and M. S. Wicha. Breast cancer, stem/progenitor cells and the estrogen receptor. Trends Endocrinol Metab 15:193-197, (2004) (Pubitemid 38833988)
    • (2004) Trends in Endocrinology and Metabolism , vol.15 , Issue.5 , pp. 193-197
    • Dontu, G.1    El-Ashry, D.2    Wicha, M.S.3
  • 8
    • 32844465160 scopus 로고    scopus 로고
    • The role of adult stem cells in carcinogenesis
    • DOI 10.1358/dnp.2005.18.9.953667
    • Romano, G. The role of adult stem cells in carcinogenesis. Drug News Perspect 18:555-559, (2005) (Pubitemid 43251106)
    • (2005) Drug News and Perspectives , vol.18 , Issue.9 , pp. 555-559
    • Romano, G.1
  • 9
    • 23044514578 scopus 로고    scopus 로고
    • Multiple drug resistance in cancer revisited: The cancer stem cell hypothesis
    • Donnenburg, V. S., and A. D. Donnenburg. Multiple drug resistance in cancer revisited: the cancer stem cell hypothesis. J Clin Pharmacol 45:872-877, (2005)
    • (2005) J Clin Pharmacol , vol.45 , pp. 872-877
    • Donnenburg, V.S.1    Donnenburg, A.D.2
  • 14
    • 33646448921 scopus 로고    scopus 로고
    • Biology of normal and acute myeloid leukemia stem cells
    • DOI 10.1532/IJH97.05144
    • Dick, J. E., and T. Lapidot. Biology of normal and acute myeloid leukemia stem cells. Int J Hematol 82:389-396, (2005) (Pubitemid 46638686)
    • (2005) International Journal of Hematology , vol.82 , Issue.5 , pp. 389-396
    • Dick, J.E.1    Lapidot, T.2
  • 15
    • 80051504560 scopus 로고    scopus 로고
    • Stem cell biology and the cellular pathways of carcinogenesis
    • Gudjonsson, T., and M. K. Magnusson. Stem cell biology and the cellular pathways of carcinogenesis. Curr Gene Ther 6:45-58, (2006)
    • (2006) Curr Gene Ther , vol.6 , pp. 45-58
    • Gudjonsson, T.1    Magnusson, M.K.2
  • 16
    • 33644879495 scopus 로고    scopus 로고
    • Mathematical model for the cancer stem cell hypothesis
    • Ganguly, R., and I. K. Puri. Mathematical model for the cancer stem cell hypothesis. Cell Prolif 39:3-14. (2006)
    • (2006) Cell Prolif , vol.39 , pp. 3-14
    • Ganguly, R.1    Puri, I.K.2
  • 18
    • 2942691389 scopus 로고    scopus 로고
    • Stem cell origin of cancer and differentiation therapy
    • DOI 10.1016/j.critrevonc.2004.04.007, PII S104084280400068X
    • Sell, S. Stem cell origin of cancer and differentiation therapy. Crit Rev Oncol Hematol 51:1-28, (2004) (Pubitemid 38781748)
    • (2004) Critical Reviews in Oncology/Hematology , vol.51 , Issue.1 , pp. 1-28
    • Sell, S.1
  • 19
    • 9244221172 scopus 로고    scopus 로고
    • Tissue repair and stem cell renewal in carcinogenesis
    • DOI 10.1038/nature03100
    • Beachy, P. A., S. S. Karhadkar, and D. M. Berman. Tissue repair and stem cell renewal in carcinogenesis. Nature 432:324-331, (2004) (Pubitemid 39551660)
    • (2004) Nature , vol.432 , Issue.7015 , pp. 324-331
    • Beachy, P.A.1    Karhadkar, S.S.2    Berman, D.M.3
  • 20
    • 0034614576 scopus 로고    scopus 로고
    • Stem cells: Units of development, units of regeneration, and units in evolution
    • Weissman, I. L. Stem cells: units of development, units of regeneration, and units in evolution. Cell 100:157-168, (2000) (Pubitemid 30046304)
    • (2000) Cell , vol.100 , Issue.1 , pp. 157-168
    • Weissman, I.L.1
  • 21
    • 13544277159 scopus 로고    scopus 로고
    • Stem cell transplantation therapy: Controversy over ethical issues and clinical relevance
    • DOI 10.1358/dnp.2004.17.10.873915
    • Romano, G. Stem cell transplantation therapy: controversy over ethical issues and clinical relevance. Drug News Perspect 17:637-645, (2004) (Pubitemid 40224049)
    • (2004) Drug News and Perspectives , vol.17 , Issue.10 , pp. 637-645
    • Romano, G.1
  • 22
    • 33847617021 scopus 로고    scopus 로고
    • From the laboratory bench to the patient's bedside: An update on clinical trials with Mesenchymal Stem Cells
    • DOI 10.1002/jcp.20959
    • Giordano, A., U. Galderisi, and I. R. Marino. From the laboratory bench to the patient's bedside: an update on clinical trials with mesenchymal srem cells. J Cell Physiol 211:27-35, (2007) (Pubitemid 46363893)
    • (2007) Journal of Cellular Physiology , vol.211 , Issue.1 , pp. 27-35
    • Giordano, A.1    Galderisi, U.2    Marino, I.R.3
  • 24
  • 25
    • 0000886345 scopus 로고
    • Nesso fisio-patologico tra la struttura dei nei materni e la genesi di alcuni tumori maligni
    • Durante, F. Nesso fisio-patologico tra la struttura dei nei materni e la genesi di alcuni tumori maligni. Arch Memor Observ Chir Pract 11:217-226, (1874)
    • (1874) Arch Memor Observ Chir Pract , vol.11 , pp. 217-226
    • Durante, F.1
  • 26
    • 34447607512 scopus 로고
    • Congenitales, quergestreiftes Muskelsarkon der Nireren
    • Cohnheim, J. Congenitales, quergestreiftes Muskelsarkon der Nireren. Virchows Arch 65:64, (1875)
    • (1875) Virchows Arch , vol.65 , pp. 64
    • Cohnheim, J.1
  • 27
    • 84956427297 scopus 로고
    • A direct measurement of the radiation sensitivity of normal mouse bone marrow cells
    • Till, J. E., and E. A. McCulloch. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat Res 14:1419-1430, (1961)
    • (1961) Radiat Res , vol.14 , pp. 1419-1430
    • Till, J.E.1    McCulloch, E.A.2
  • 28
    • 0014156312 scopus 로고
    • Teratocarcinoma: Model for a developmental concept of cancer
    • Pierce, G. B. Teratocarcinoma: model for a developmental concept of cancer. Curr Top Dev Biol 2:223-246, (1967)
    • (1967) Curr Top Dev Biol , vol.2 , pp. 223-246
    • Pierce, G.B.1
  • 29
  • 30
    • 0029983762 scopus 로고    scopus 로고
    • Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell
    • DOI 10.1006/dbio.1996.0090
    • Reynolds, B. A., and S. Weiss. Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Dev Biol 175:1-13, (1996) (Pubitemid 26150042)
    • (1996) Developmental Biology , vol.175 , Issue.1 , pp. 1-13
    • Reynolds, B.A.1    Weiss, S.2
  • 31
    • 0033556163 scopus 로고    scopus 로고
    • Dissociation between resistance to apoptosis and the transformed phenotype in IGF-I receptor signaling
    • DOI 10.1002/(SICI)1097-4644(19990201)72:2<294::AID-JCB14>3.0.CO;2-0
    • Romano, G., M. Prisco, T. Zanocco-Marani, F. Peruzzi, B. Valentinis, and R. Baserga. Dissociation between resistance to apoptosis and the transformed cell phenotype in IGF-1 receptor signaling. J Cell Biochem 72:294-310, (1999) (Pubitemid 29021943)
    • (1999) Journal of Cellular Biochemistry , vol.72 , Issue.2 , pp. 294-310
    • Romano, G.1    Prisco, M.2    Zanocco-Marani, T.3    Peruzzi, F.4    Valentinis, B.5    Baserga, R.6
  • 32
    • 0344013487 scopus 로고    scopus 로고
    • The Complex Biology of the Receptor for the Insulin-Like Growth Factor-1
    • DOI 10.1358/dnp.2003.16.8.829351
    • Romano, G. The complex biology of the receptor for the insulin-like growth factor-1. Drug News Perspect 16:525-531, (2003) (Pubitemid 37484371)
    • (2003) Drug News and Perspectives , vol.16 , Issue.8 , pp. 525-531
    • Romano, G.1
  • 33
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
    • Liu, S., G. Dontu, I. D. Mantle, S. Patel, N. S. Ahn, K. W. Jackson, P. Suri, and M. S. Wicha. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res 66:6063-6071, (2006)
    • (2006) Cancer Res , vol.66 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3    Patel, S.4    Ahn, N.S.5    Jackson, K.W.6    Suri, P.7    Wicha, M.S.8
  • 34
    • 18944407603 scopus 로고    scopus 로고
    • Mammary stem cells, self-renewal pathways, and carcinogenesis
    • DOI 10.1186/bcr1021, 86
    • Liu, S., G. Dontu, and M. S. Wicha. Mammary stem cells, self-renewal pathways, and carcinogenesis. Breast Cancer Res 7:86-95, (2005) (Pubitemid 40704127)
    • (2005) Breast Cancer Research , vol.7 , Issue.3 , pp. 86-95
    • Liu, S.1    Dontu, G.2    Wicha, M.S.3
  • 36
    • 0029841366 scopus 로고    scopus 로고
    • Mutations in the human homologue of Drosophila patched (PTCH) in basal cell carcinomas and the Gorlin syndrome: Different in vivo mechanisms of PTCH inactivation
    • Unden, A. B., E. Holmberg, B. Lundh-Rozel, M. Stahle-Backdahl, P. G. Zaphiropoulos, R. Toftgard, and I. Vorechovsky. Mutations in the human homologue of Drosophila patched (PTCH) carcinomas and the Gorlin syndrome: different in vivo mechanisms of PTCH inactivation. Cancer Res 56:4562-4565, (1996) (Pubitemid 26338046)
    • (1996) Cancer Research , vol.56 , Issue.20 , pp. 4562-4565
    • Unden, A.B.1    Holmberg, E.2    Lundh-Rozell, B.3    Stahle-Backdahl, M.4    Zaphiropoulos, P.G.5    Toftgard, R.6    Vorechovsky, I.7
  • 39
    • 33746092455 scopus 로고    scopus 로고
    • Mutual, reciprocal SDF-1/CXCR4 interactions between hematopoietic and bone marrow stromal cells regulate human stem cell migration and development in NOD/SCID chimeric mice
    • DOI 10.1016/j.exphem.2006.04.002, PII S0301472X06002402
    • Dar, A., O. Kollet, and T. Lapidot. Mutual, reciprocal SDF-1/CXCR4 interactions between hematopoietic and bone marrow stromal cells regulate human stem cell migration and development in NOD/SCID chimeric mice. Exp Hematol 34:967-975, (2006) (Pubitemid 44080383)
    • (2006) Experimental Hematology , vol.34 , Issue.8 , pp. 967-975
    • Dar, A.1    Kollet, O.2    Lapidot, T.3
  • 40
    • 0033613401 scopus 로고    scopus 로고
    • Involvement of Notch1 in the development of mouse mammary tumors
    • DOI 10.1038/sj.onc.1202991
    • Dievart, A., N. Beaulieu, and P. Jolicoeur. Involvement of Notch-1 in the development of mouse mammary tumors. Oncogene 18:5973-5981, (1999) (Pubitemid 29535009)
    • (1999) Oncogene , vol.18 , Issue.44 , pp. 5973-5981
    • Dievart, A.1    Beaulieu, N.2    Jolicoeur, P.3
  • 42
    • 0242456129 scopus 로고    scopus 로고
    • Notch signaling as a therapeutic target in cancer: A new approach to the development of cell fate modifying agents
    • Nickoloff, Y., J. C. Aste, and S. C. Blacklow. Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene 22:6598-6608, (2003)
    • (2003) Oncogene , vol.22 , pp. 6598-6608
    • Nickoloff, Y.1    Aste, J.C.2    Blacklow, S.C.3
  • 45
    • 0042872887 scopus 로고    scopus 로고
    • MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice
    • DOI 10.1016/S1535-6108(03)00019-9
    • So, C. W., H. Karsunky, E. Passegue, A. Cozzio, I. L. Weissman, and M. L. Cleary. MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineages leukemias in mice. Cancer Cell 3:161-171, (2003) (Pubitemid 37443388)
    • (2003) Cancer Cell , vol.3 , Issue.2 , pp. 161-171
    • So, C.W.1    Karsunky, H.2    Passegue, E.3    Cozzio, A.4    Weissman, I.L.5    Cleary, M.L.6
  • 46
    • 0346100567 scopus 로고    scopus 로고
    • Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors
    • DOI 10.1101/gad.1143403
    • Cozzio, A., E. Passegue, P. M. Ayton, H. Karsunky, M. L. Cleary, and I. L. Weissman. Similar MLL-associated leukemias arising from self-renewing stem cells and shortlived myeloid progenitors. Genes Dev 17:3029-3035, (2003) (Pubitemid 38040767)
    • (2003) Genes and Development , vol.17 , Issue.24 , pp. 3029-3035
    • Cozzio, A.1    Passegue, E.2    Ayton, P.M.3    Karsunky, H.4    Cleary, M.L.5    Weissman, I.L.6
  • 52
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • DOI 10.1016/j.cell.2005.02.034, PII S0092867405002370
    • Orimo, A., P. B. Gupta, D. C. Sgroi, F. Arenzana-Seisdedos, T. Delaunary, R. Naeem, V. J. Carey, A. L. Richardson, and R. A. Weinberg. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121:335-348, (2005) (Pubitemid 40692295)
    • (2005) Cell , vol.121 , Issue.3 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 55
    • 33750527295 scopus 로고    scopus 로고
    • Perspectives and controversies in the field of stem cell research
    • Romano, G. Perspectives and controversies in the field of stem cell research. Drug News Perspect 19:433-439, (2006) (Pubitemid 44662172)
    • (2006) Drug News and Perspectives , vol.19 , Issue.7 , pp. 433-439
    • Romano, G.1
  • 56
    • 33646376411 scopus 로고    scopus 로고
    • Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
    • DOI 10.1038/nature04703, PII NATURE04703
    • Yilmaz, O. H., R. Valdez, B. K. Theisen, W. Guo, D. O. Ferguson, H. Wu, and S. J. Morrison. Pten dependence distinguishes haematopoietic stem cells from leukaemiainitiating cells. Nature 441:475-482, (2006) (Pubitemid 44050144)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 475-482
    • Yilmaz, O.H.1    Valdez, R.2    Theisen, B.K.3    Guo, W.4    Ferguson, D.O.5    Wu, H.6    Morrison, S.J.7
  • 60
    • 0031785612 scopus 로고    scopus 로고
    • Clinical implications of prostate-specific antigen (PSA)
    • DOI 10.1097/00042307-199809000-00007
    • Oakley, N. Clinical implications for prostate-specific antigen (PSA) Curr Opin Urol 8:401-406, (1998) (Pubitemid 28479233)
    • (1998) Current Opinion in Urology , vol.8 , Issue.5 , pp. 401-406
    • Oakley, N.1
  • 62
    • 38349179764 scopus 로고    scopus 로고
    • Early detection of ovarian cancer: New technologies in pursuit of a disease that is neither common nor rare
    • Bast, R. C. Early detection of ovarian cancer: new technologies in pursuit of a disease that is neither common nor rare. Trans Am Clin Climatol Assoc 115:233-248, (2004)
    • (2004) Trans Am Clin Climatol Assoc , vol.115 , pp. 233-248
    • Bast, R.C.1
  • 63
    • 20444457518 scopus 로고    scopus 로고
    • Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
    • DOI 10.1172/JCI23412
    • Glinsky, G. V., O. Berezovska, and A. B. Glinsky. Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. J Clin Invest 115:1503-1521, (2005) (Pubitemid 40814659)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.6 , pp. 1503-1521
    • Glinsky, G.V.1    Berezovska, O.2    Glinskii, A.B.3
  • 65
    • 4644319204 scopus 로고    scopus 로고
    • Stem cells and cancer: The polycomb connection
    • DOI 10.1016/j.cell.2004.08.005, PII S0092867404007457
    • Valk-Lingbeek, M. E., S. W. Bruggeman, and M. van Lohuizen. Stem cells and cancer: the polycomb connection. Cell 118:409-418, (2004) (Pubitemid 39485661)
    • (2004) Cell , vol.118 , Issue.4 , pp. 409-418
    • Valk-Lingbeek, M.E.1    Bruggeman, S.W.M.2    Van Lohuizen, M.3
  • 66
    • 0038349957 scopus 로고    scopus 로고
    • Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
    • DOI 10.1038/nature01587
    • Park, I. K., D. Qian, M. Kiel, M. W. Becker, M. Pihalja, I. L. Weissman, S. J. Morrison, and M. F. Clarke. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 423:302-305, (2003) (Pubitemid 40852701)
    • (2003) Nature , vol.423 , Issue.6937 , pp. 302-305
    • Park, I.-K.1    Qian, D.2    Kiel, M.3    Becker, M.W.4    Pihalja, M.5    Weissman, I.L.6    Morrison, S.J.7    Clarke, M.F.8
  • 67
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • DOI 10.1038/nature02060
    • Molofsky, A. V., R. Pardal, T. Iwashita, I. K. Park, M. F. Clarke, and S. J. Morrison. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425:962-967, (2003) (Pubitemid 37376927)
    • (2003) Nature , vol.425 , Issue.6961 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.-K.4    Clarke, M.F.5    Morrison, S.J.6


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