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Volumn 2, Issue 1, 2007, Pages

Sp1 is essential for p16INK4a expression in human diploid fibroblasts during senescence

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; MITHRAMYCIN; PLASMID VECTOR; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; BETA GALACTOSIDASE;

EID: 39449128749     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000164     Document Type: Article
Times cited : (42)

References (39)
  • 1
    • 50549218525 scopus 로고
    • The limited in vitro lifespan of human diploid cell strains
    • Hayflick L (1965) The limited in vitro lifespan of human diploid cell strains. Exp. Cell Res. 37: 614-636.
    • (1965) Exp. Cell Res , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 2
    • 0035500487 scopus 로고    scopus 로고
    • Cellular senescence as a tumor-suppressor mechanism
    • Campisi J (2001) Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol. 11: 27-31.
    • (2001) Trends Cell Biol , vol.11 , pp. 27-31
    • Campisi, J.1
  • 3
    • 1342329228 scopus 로고    scopus 로고
    • mRNA level of alpha-2-macroglobulin as an aging biomarker of human fibroblasts in culture
    • Ma H, Li RZ, Zhang ZY, Tong TJ (2004) mRNA level of alpha-2-macroglobulin as an aging biomarker of human fibroblasts in culture. Exp. Gerontol. 39: 415-421.
    • (2004) Exp. Gerontol , vol.39 , pp. 415-421
    • Ma, H.1    Li, R.Z.2    Zhang, Z.Y.3    Tong, T.J.4
  • 4
    • 3242707579 scopus 로고    scopus 로고
    • Cloning and Characterization of Cellular Senescence-Associated Genes in Human Fibroblast Cell by Suppression Subtractive Hybridization
    • Guo SZ, Zhang ZY, Tong TJ (2004) Cloning and Characterization of Cellular Senescence-Associated Genes in Human Fibroblast Cell by Suppression Subtractive Hybridization. Exp. Cell Res. 298: 465-472.
    • (2004) Exp. Cell Res , vol.298 , pp. 465-472
    • Guo, S.Z.1    Zhang, Z.Y.2    Tong, T.J.3
  • 5
    • 0029834145 scopus 로고    scopus 로고
    • Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-kappa B
    • Helenius M, Hanninen M, Lehtinen SK, Salminen A (1996) Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-kappa B. Biochem. J. 318(Pt 2): 603-608.
    • (1996) Biochem. J , vol.318 , Issue.PART 2 , pp. 603-608
    • Helenius, M.1    Hanninen, M.2    Lehtinen, S.K.3    Salminen, A.4
  • 6
    • 0033989829 scopus 로고    scopus 로고
    • Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor
    • Dimri GP, Itahana K, Acosta M, Campisi J (2000) Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor. Mol. Cell Biol. 20: 273-285.
    • (2000) Mol. Cell Biol , vol.20 , pp. 273-285
    • Dimri, G.P.1    Itahana, K.2    Acosta, M.3    Campisi, J.4
  • 8
    • 0034028836 scopus 로고    scopus 로고
    • Tumor suppressors and oncogenes in cellular senescence
    • Bringold F, Serrano M (2000) Tumor suppressors and oncogenes in cellular senescence. Exp. Gerontol. 35: 317-329.
    • (2000) Exp. Gerontol , vol.35 , pp. 317-329
    • Bringold, F.1    Serrano, M.2
  • 9
    • 0034644274 scopus 로고    scopus 로고
    • PML regulates p53 acetylation and premature senescence induced by oncogenic
    • Pearson M, Carbone R, Sebastiani C, Cioce M, Fagioli M, et al. (2000) PML regulates p53 acetylation and premature senescence induced by oncogenic Ras. Nature. 406: 207-210.
    • (2000) Ras. Nature , vol.406 , pp. 207-210
    • Pearson, M.1    Carbone, R.2    Sebastiani, C.3    Cioce, M.4    Fagioli, M.5
  • 10
    • 0037663490 scopus 로고    scopus 로고
    • Werner syndrome protein limits MYC-induced cellular senescence
    • Grandori C, Wu KJ, Fernandez P, Ngouenet C, Grim J, et al. (2003) Werner syndrome protein limits MYC-induced cellular senescence. Gene Dev. 17: 1569-1574.
    • (2003) Gene Dev , vol.17 , pp. 1569-1574
    • Grandori, C.1    Wu, K.J.2    Fernandez, P.3    Ngouenet, C.4    Grim, J.5
  • 11
  • 12
    • 0030609861 scopus 로고    scopus 로고
    • Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts
    • Brown JP, Wei W, Sedivy JM (1997) Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts. Science. 277: 831-834.
    • (1997) Science , vol.277 , pp. 831-834
    • Brown, J.P.1    Wei, W.2    Sedivy, J.M.3
  • 13
    • 0033528830 scopus 로고    scopus 로고
    • p21Waf1/ Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53
    • Fang L, Igarashi M, Leung J, Sugrue MM, Lee SW, et al. (1999) p21Waf1/ Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53. Oncogene. 18: 2789-2797.
    • (1999) Oncogene , vol.18 , pp. 2789-2797
    • Fang, L.1    Igarashi, M.2    Leung, J.3    Sugrue, M.M.4    Lee, S.W.5
  • 14
    • 1642540254 scopus 로고    scopus 로고
    • BRG1 controls the activity of the retinoblastoma protein via regulation of p21CIP1/WAF1/SDI
    • Kang H, Cui K, Zhao K (2004) BRG1 controls the activity of the retinoblastoma protein via regulation of p21CIP1/WAF1/SDI. Mol. Cell Biol. 24: 1188-1199.
    • (2004) Mol. Cell Biol , vol.24 , pp. 1188-1199
    • Kang, H.1    Cui, K.2    Zhao, K.3
  • 15
    • 0033564106 scopus 로고    scopus 로고
    • p16/pRb pathway alterations are required for bypassing senescence in human prostate epithelial cells
    • Jarrard DF, Sarkar S, Shi Y, Yeager TR, Magrane G, et al. (1999) p16/pRb pathway alterations are required for bypassing senescence in human prostate epithelial cells. Cancer Res. 59: 2957-2964.
    • (1999) Cancer Res , vol.59 , pp. 2957-2964
    • Jarrard, D.F.1    Sarkar, S.2    Shi, Y.3    Yeager, T.R.4    Magrane, G.5
  • 16
    • 0034704848 scopus 로고    scopus 로고
    • p16 INK4a can initiate an autonomous senescence program
    • Dai CY, Enders GH (2000) p16 INK4a can initiate an autonomous senescence program. Oncogene. 19: 1613-1622.
    • (2000) Oncogene , vol.19 , pp. 1613-1622
    • Dai, C.Y.1    Enders, G.H.2
  • 17
    • 0034656419 scopus 로고    scopus 로고
    • p16INK4A mediates cyclin dependent kinase 4 and 6 inhibition in senescent prostatic epithelial cells
    • Sandhu C, Peehl DM, Slingerland J (2000) p16INK4A mediates cyclin dependent kinase 4 and 6 inhibition in senescent prostatic epithelial cells. Cancer Res. 60: 2616-2622.
    • (2000) Cancer Res , vol.60 , pp. 2616-2622
    • Sandhu, C.1    Peehl, D.M.2    Slingerland, J.3
  • 18
    • 0035930621 scopus 로고    scopus 로고
    • Senescence delay of human diploid fibroblast induced by anti-sense p16INK4a expression
    • Duan JM, Zhang ZY, Tong TJ (2001) Senescence delay of human diploid fibroblast induced by anti-sense p16INK4a expression. J. Biol. Chem. 276: 48325-48331.
    • (2001) J. Biol. Chem , vol.276 , pp. 48325-48331
    • Duan, J.M.1    Zhang, Z.Y.2    Tong, T.J.3
  • 20
    • 0030477686 scopus 로고    scopus 로고
    • Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
    • Alcorta DA, Xiong Y, Phelps D, Hannon G, Beach D, et al. (1996) Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proc. Natl. Acad. Sci. USA 93: 13742-13747.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13742-13747
    • Alcorta, D.A.1    Xiong, Y.2    Phelps, D.3    Hannon, G.4    Beach, D.5
  • 21
    • 0037214382 scopus 로고    scopus 로고
    • Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1
    • Itahana K, Zou Y, Itahana Y, Martinez JL, Beausejour C, et al. (2003) Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1. Mol. Cell Biol. 23: 389-401.
    • (2003) Mol. Cell Biol , vol.23 , pp. 389-401
    • Itahana, K.1    Zou, Y.2    Itahana, Y.3    Martinez, J.L.4    Beausejour, C.5
  • 22
    • 0035931859 scopus 로고    scopus 로고
    • Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
    • Ohtani N, Zebedee Z, Huot TJ, Stinson JA, Sugimoto M, et al. (2001) Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence. Nature. 409: 1067-1070.
    • (2001) Nature , vol.409 , pp. 1067-1070
    • Ohtani, N.1    Zebedee, Z.2    Huot, T.J.3    Stinson, J.A.4    Sugimoto, M.5
  • 23
    • 0034660640 scopus 로고    scopus 로고
    • JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression
    • Passegue E, Wagner EF (2000) JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression. EMBO J. 19: 2969-2979.
    • (2000) EMBO J , vol.19 , pp. 2969-2979
    • Passegue, E.1    Wagner, E.F.2
  • 24
    • 1842850619 scopus 로고    scopus 로고
    • Sp1 is involved in the transcriptional activation of p16(INK4) by p21(Waf1) in HeLa cells
    • Xue L, Wu J, Zheng W, Wang P, Li J, et al. (2004) Sp1 is involved in the transcriptional activation of p16(INK4) by p21(Waf1) in HeLa cells. FEBS Lett. 564: 199-204.
    • (2004) FEBS Lett , vol.564 , pp. 199-204
    • Xue, L.1    Wu, J.2    Zheng, W.3    Wang, P.4    Li, J.5
  • 26
    • 0035966101 scopus 로고    scopus 로고
    • Characterization of regulatory elements on the promoter region of p16(INK4a) that contribute to over-expression of p16 in senescent fibroblasts
    • Wang W, Wu JF, Zhang ZY, Tong TJ (2001) Characterization of regulatory elements on the promoter region of p16(INK4a) that contribute to over-expression of p16 in senescent fibroblasts. J. Biol Chem. 276: 48655-48661.
    • (2001) J. Biol Chem , vol.276 , pp. 48655-48661
    • Wang, W.1    Wu, J.F.2    Zhang, Z.Y.3    Tong, T.J.4
  • 27
    • 0028202945 scopus 로고
    • Cell aging of human diploid fibroblasts is associated with changes in responsiveness to epidermal growth factor and changes in HER-2 expression
    • Tang ZQ, Zhang ZY, Zheng YS, Corbley MJ, Tong TJ (1994) Cell aging of human diploid fibroblasts is associated with changes in responsiveness to epidermal growth factor and changes in HER-2 expression. Mech. Ageing Dev. 73: 57-67.
    • (1994) Mech. Ageing Dev , vol.73 , pp. 57-67
    • Tang, Z.Q.1    Zhang, Z.Y.2    Zheng, Y.S.3    Corbley, M.J.4    Tong, T.J.5
  • 28
    • 0029003790 scopus 로고
    • The proliferative response and anti-oncogene expression in old 2BS cells after growth factor stimulation
    • Li JH, Zhang ZY, Tong TJ (1995) The proliferative response and anti-oncogene expression in old 2BS cells after growth factor stimulation. Mech. Ageing Dev. 80: 25-34.
    • (1995) Mech. Ageing Dev , vol.80 , pp. 25-34
    • Li, J.H.1    Zhang, Z.Y.2    Tong, T.J.3
  • 29
    • 0033960283 scopus 로고    scopus 로고
    • Differential role for Sp1/Sp3 transcription factors in the regulation of the promoter activity of multiple cyclin-dependent kinase inhibitor genes
    • Pagliuca A, Gallo P, Lania L (2000) Differential role for Sp1/Sp3 transcription factors in the regulation of the promoter activity of multiple cyclin-dependent kinase inhibitor genes. J. Cell Biochem. 76: 360-367.
    • (2000) J. Cell Biochem , vol.76 , pp. 360-367
    • Pagliuca, A.1    Gallo, P.2    Lania, L.3
  • 31
    • 0033538431 scopus 로고    scopus 로고
    • Functional interactions between Sp1 or Sp3 and the helicase-like transcription factor mediate basal expression from the human plasminogen activator inhibitor-1 gene
    • Ding H, Benotmane AM, Suske G, Collen D, Belayew A (1999) Functional interactions between Sp1 or Sp3 and the helicase-like transcription factor mediate basal expression from the human plasminogen activator inhibitor-1 gene. J. Biol. Chem. 274: 19573-19580.
    • (1999) J. Biol. Chem , vol.274 , pp. 19573-19580
    • Ding, H.1    Benotmane, A.M.2    Suske, G.3    Collen, D.4    Belayew, A.5
  • 32
    • 0035830950 scopus 로고    scopus 로고
    • Sp1 and Sp3 physically interact and cooperate with GABP for the activation of the utrophin promoter
    • Galvagni F, Capo S, Oliviero S (2001) Sp1 and Sp3 physically interact and cooperate with GABP for the activation of the utrophin promoter. J. Mol. Biol. 306: 985-996.
    • (2001) J. Mol. Biol , vol.306 , pp. 985-996
    • Galvagni, F.1    Capo, S.2    Oliviero, S.3
  • 33
    • 0030772457 scopus 로고    scopus 로고
    • O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions
    • Roos MD, Su K, Baker JR, Kudlow JE (1997) O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions. Mol. Cell Biol. 17: 6472-6480.
    • (1997) Mol. Cell Biol , vol.17 , pp. 6472-6480
    • Roos, M.D.1    Su, K.2    Baker, J.R.3    Kudlow, J.E.4
  • 34
    • 0030907389 scopus 로고    scopus 로고
    • Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility
    • Han I, Kudlow JE (1997) Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility. Mol. Cell Biol. 17: 2550-2558.
    • (1997) Mol. Cell Biol , vol.17 , pp. 2550-2558
    • Han, I.1    Kudlow, J.E.2
  • 35
    • 0024280897 scopus 로고
    • O-glycosylation of eukaryotic transcription factors: Implications for mechanisms of transcriptional regulation
    • Jackson SP, Tjian R (1988) O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation. Cell. 55: 125-133.
    • (1988) Cell , vol.55 , pp. 125-133
    • Jackson, S.P.1    Tjian, R.2
  • 36
    • 0030973394 scopus 로고    scopus 로고
    • Casein kinase II-mediated phosphorylation of the C terminus of Sp1 decreases its DNA binding activity
    • Armstrong SA, Barry DA, Leggett RW, Mueller CR (1997) Casein kinase II-mediated phosphorylation of the C terminus of Sp1 decreases its DNA binding activity. J. Biol. Chem. 272: 13489-13495.
    • (1997) J. Biol. Chem , vol.272 , pp. 13489-13495
    • Armstrong, S.A.1    Barry, D.A.2    Leggett, R.W.3    Mueller, C.R.4
  • 37
    • 0035282882 scopus 로고    scopus 로고
    • Sp1 phosphorylation regulates inducible expression of platelet-derived growth factor B-chain gene via atypical protein kinase C-zeta
    • Rafty LA, Khachigian LM (2001) Sp1 phosphorylation regulates inducible expression of platelet-derived growth factor B-chain gene via atypical protein kinase C-zeta. Nucleic Acids Res. 29: 1027-1033.
    • (2001) Nucleic Acids Res , vol.29 , pp. 1027-1033
    • Rafty, L.A.1    Khachigian, L.M.2
  • 38
    • 0032802314 scopus 로고    scopus 로고
    • Histone deacetylase 1 can repress transcription by binding to Sp1.Mol
    • Doetzlhofer A, Rotheneder H, Lagger G, Koranda M, Kurtev V, et al. (1999) Histone deacetylase 1 can repress transcription by binding to Sp1.Mol. Cell Biol. 19: 5504-5511.
    • (1999) Cell Biol , vol.19 , pp. 5504-5511
    • Doetzlhofer, A.1    Rotheneder, H.2    Lagger, G.3    Koranda, M.4    Kurtev, V.5
  • 39
    • 0035876388 scopus 로고    scopus 로고
    • Wagner M, Brosch G, Zwerschke W, Seto E, Loidl P, et al. (2001) Histone deacetylases in replicative senescence: evidence for a senescence-specific form of HDAC-2.FEBS Lett. 499: 101-106.
    • Wagner M, Brosch G, Zwerschke W, Seto E, Loidl P, et al. (2001) Histone deacetylases in replicative senescence: evidence for a senescence-specific form of HDAC-2.FEBS Lett. 499: 101-106.


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