-
1
-
-
0025970571
-
Increased gene expression of Alzheimer disease beta-amyloid precursor protein in senescent cultured fibroblasts
-
Alder M.J., Coronel C., Shelton E., Seegmiller J.E., Dewji N.N. Increased gene expression of Alzheimer disease beta-amyloid precursor protein in senescent cultured fibroblasts. Proc. Natl Acad. Sci. USA. 88:1991;16-20.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 16-20
-
-
Alder, M.J.1
Coronel, C.2
Shelton, E.3
Seegmiller, J.E.4
Dewji, N.N.5
-
2
-
-
0026460896
-
Telomere length predicts replicative capacity of human fibroblasts
-
Allsopp R.C., Vaziri H., Patterson C., Goldstein S., Younglai E.V., Futcher A.B., Greider C.W., Harley C.B. Telomere length predicts replicative capacity of human fibroblasts. Proc. Natl Acad. Sci. USA. 89:1992;10114-10118.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 10114-10118
-
-
Allsopp, R.C.1
Vaziri, H.2
Patterson, C.3
Goldstein, S.4
Younglai, E.V.5
Futcher, A.B.6
Greider, C.W.7
Harley, C.B.8
-
3
-
-
17344362232
-
Alpha-2-macroglobulin is genetically associated with Alzheimer's disease
-
Blacker D., Wilcox M.A., Laird N.M., Rodes L., Horvath S.M., Go R.C., Perry R., Watson J.B., Bassatt S.S., McInnis M.G., Albert M.S., Hyman B.T., Tanzi R.E. Alpha-2-macroglobulin is genetically associated with Alzheimer's disease. Nat. Genet. 19:1998;357-360.
-
(1998)
Nat. Genet.
, vol.19
, pp. 357-360
-
-
Blacker, D.1
Wilcox, M.A.2
Laird, N.M.3
Rodes, L.4
Horvath, S.M.5
Go, R.C.6
Perry, R.7
Watson, J.B.8
Bassatt, S.S.9
McInnis, M.G.10
Albert, M.S.11
Hyman, B.T.12
Tanzi, R.E.13
-
4
-
-
0032531126
-
Premature induction of aging in sublethally H2O2-treated young MRC5 fibroblasts correlates with increased glutathione peroxidase levels and resistance to DNA breakage
-
Caldini R., Chevanne M., Mocali A., Tombaccini D., Paoletti F. Premature induction of aging in sublethally H2O2-treated young MRC5 fibroblasts correlates with increased glutathione peroxidase levels and resistance to DNA breakage. Mech. Ageing Dev. 105:1998;137-150.
-
(1998)
Mech. Ageing Dev.
, vol.105
, pp. 137-150
-
-
Caldini, R.1
Chevanne, M.2
Mocali, A.3
Tombaccini, D.4
Paoletti, F.5
-
5
-
-
0035325264
-
Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts
-
Chen Q.M., Prowse K.R., Tu V.C., Purdom S., Linskens M.H. Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts. Exp. Cell Res. 265:2001;294-303.
-
(2001)
Exp. Cell Res.
, vol.265
, pp. 294-303
-
-
Chen, Q.M.1
Prowse, K.R.2
Tu, V.C.3
Purdom, S.4
Linskens, M.H.5
-
6
-
-
0025185228
-
Age-dependent decrease in heat-inducible DNA sequence-specific binding activity in human diploid fibroblasts
-
Choi H.S., Lin Z., Li B.S., Liu A.Y. Age-dependent decrease in heat-inducible DNA sequence-specific binding activity in human diploid fibroblasts. J. Biol. Chem. 265:1990;18005-18011.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 18005-18011
-
-
Choi, H.S.1
Lin, Z.2
Li, B.S.3
Liu, A.Y.4
-
7
-
-
0029006174
-
Alterations in the molecular response to DNA damage during cellular aging of cultured fibroblasts: Reduced Ap-1activation and collagenase gene expression
-
Choi A.M.K., Pignolo R.J., Rhys C.M.J., Cristifalo V.J., Holbrook N.J. Alterations in the molecular response to DNA damage during cellular aging of cultured fibroblasts: reduced Ap-1activation and collagenase gene expression. J. Cell Physiol. 164:1995;65-74.
-
(1995)
J. Cell Physiol.
, vol.164
, pp. 65-74
-
-
Choi, A.M.K.1
Pignolo, R.J.2
Rhys, C.M.J.3
Cristifalo, V.J.4
Holbrook, N.J.5
-
8
-
-
0028174104
-
Classification of alpha 2-macroglobulin-cytokine interactions based on affinity of noncovalent association in solution under apparent equilibrium conditions
-
Crookston K.P., Webb D.J., Wolf B.B., Gonias S.L.J. Classification of alpha 2-macroglobulin-cytokine interactions based on affinity of noncovalent association in solution under apparent equilibrium conditions. J. Biol. Chem. 269:1994;1533-1540.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1533-1540
-
-
Crookston, K.P.1
Webb, D.J.2
Wolf, B.B.3
Gonias, S.L.J.4
-
9
-
-
0026800776
-
Overexpression of two-chain form of cathepsin B in senescent WI-38 cells
-
DiPaolo B.R., Pignolo R.J., Cristifalo V.J. Overexpression of two-chain form of cathepsin B in senescent WI-38 cells. Exp. Cell Res. 201:1992;500-505.
-
(1992)
Exp. Cell Res.
, vol.201
, pp. 500-505
-
-
Dipaolo, B.R.1
Pignolo, R.J.2
Cristifalo, V.J.3
-
10
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri G.P., Lee X., Basile G., Acosta M., Scott G., Roskelley C., Medrano E.E., Linskens M., Rubelj I., Pereira-Smith O. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl Acad. Sci. USA. 92:1995;9363-9367.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
-
12
-
-
0033963144
-
Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast
-
Dumont P., Burton M., Chen Q.M., Gonos E.S., Frippiat C., Mazarati J.B., Eliaers F., Remacle J., Toussaint O. Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast. Free Radic Biol. Med. 28:2000;361-373.
-
(2000)
Free Radic Biol. Med.
, vol.28
, pp. 361-373
-
-
Dumont, P.1
Burton, M.2
Chen, Q.M.3
Gonos, E.S.4
Frippiat, C.5
Mazarati, J.B.6
Eliaers, F.7
Remacle, J.8
Toussaint, O.9
-
13
-
-
0035951791
-
2 stress triggers a release of transforming growth factor-beta 1, which induces biomarkers of cellular senescence of human diploid fibroblasts
-
2 stress triggers a release of transforming growth factor-beta 1, which induces biomarkers of cellular senescence of human diploid fibroblasts. J. Biol. Chem. 276:2001;2531-2537.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2531-2537
-
-
Frippiat, C.1
Chen, Q.M.2
Zdanov, S.3
Magalhaes, J.P.4
Remacle, J.5
Toussaint, O.6
-
14
-
-
0025145238
-
Replicative senescence: The human fibroblast comes of age
-
Goldstein S. Replicative senescence: the human fibroblast comes of age. Science. 249:1990;1129-1133.
-
(1990)
Science
, vol.249
, pp. 1129-1133
-
-
Goldstein, S.1
-
15
-
-
0028113386
-
Alpha 2-macroglobulin and the alpha 2-macroglobulin receptor/LRP. A growth regulatory axis
-
Gonias S.L., LaMarre J., Crookston K.P., Webb D.J., Wolf B.B., Lopes M.B., Moses H.L., Hayes M.A. Alpha 2-macroglobulin and the alpha 2-macroglobulin receptor/LRP. A growth regulatory axis. Ann. NY Acad. Sci. 737:1994;173-190.
-
(1994)
Ann. NY Acad. Sci.
, vol.737
, pp. 173-190
-
-
Gonias, S.L.1
Lamarre, J.2
Crookston, K.P.3
Webb, D.J.4
Wolf, B.B.5
Lopes, M.B.6
Moses, H.L.7
Hayes, M.A.8
-
16
-
-
50549218525
-
The limited in vitro lifetime of human diploid strains
-
Hayflick L. The limited in vitro lifetime of human diploid strains. Exp. Cell Res. 37:1965;614-636.
-
(1965)
Exp. Cell Res.
, vol.37
, pp. 614-636
-
-
Hayflick, L.1
-
17
-
-
0032539723
-
Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation
-
Hughes S.R., Khorkova O., Goyal S., Knaeblein J., Heroux J., Riedel N.G., Sahasrabudhe S. Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation. Proc. Natl Acad. Sci. USA. 95:1998;3275-3280.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 3275-3280
-
-
Hughes, S.R.1
Khorkova, O.2
Goyal, S.3
Knaeblein, J.4
Heroux, J.5
Riedel, N.G.6
Sahasrabudhe, S.7
-
18
-
-
0035096154
-
Two-dimensional gel electrophoretic studies on the cellular aging: Accumulation of alpha-2-macroglobulin in human fibroblasts with aging
-
Kondo T., Sakaguchi M., Namba M. Two-dimensional gel electrophoretic studies on the cellular aging: accumulation of alpha-2-macroglobulin in human fibroblasts with aging. Exp. Gerontol. 36:2001;487-495.
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 487-495
-
-
Kondo, T.1
Sakaguchi, M.2
Namba, M.3
-
19
-
-
0031732328
-
Expression profile of senescence-associated beta-galactosidase and activation of telomerase in human ovarian surface epithelial cells undergoing immortalization
-
Litaker J.R., Pan J., Cheung Y., Zhang D.K., Liu Y., Wong S.C. Expression profile of senescence-associated beta-galactosidase and activation of telomerase in human ovarian surface epithelial cells undergoing immortalization. Int. J. Oncol. 13:1998;951-956.
-
(1998)
Int. J. Oncol.
, vol.13
, pp. 951-956
-
-
Litaker, J.R.1
Pan, J.2
Cheung, Y.3
Zhang, D.K.4
Liu, Y.5
Wong, S.C.6
-
20
-
-
0035824641
-
Identification of the high affinity binding site in transforming growth factor-beta involved in complex formation with alpha 2-macroglobulin. Implications regarding the molecular mechanisms of complex formation between alpha 2-macroglobulin and growth factors, cytokines, and hormones
-
Liu Q., Ling T.Y., Shieh H.S., Johnson F.E., Huang S.S. Identification of the high affinity binding site in transforming growth factor-beta involved in complex formation with alpha 2-macroglobulin. Implications regarding the molecular mechanisms of complex formation between alpha 2-macroglobulin and growth factors, cytokines, and hormones. J. Biol. Chem. 276:2001;46212-46218.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46212-46218
-
-
Liu, Q.1
Ling, T.Y.2
Shieh, H.S.3
Johnson, F.E.4
Huang, S.S.5
-
22
-
-
0036765026
-
The effects of epidermal growth factor on gene expression in human fibroblasts
-
Ma H., Zhang Z.Y., Tong T.J. The effects of epidermal growth factor on gene expression in human fibroblasts. In Vitro Cell Dev. Biol. Anim. 38:2002;481-486.
-
(2002)
In Vitro Cell Dev. Biol. Anim.
, vol.38
, pp. 481-486
-
-
Ma, H.1
Zhang, Z.Y.2
Tong, T.J.3
-
24
-
-
0014816132
-
Replicative lifespan of cultivated human cells. Effects of dornor's age, tissue and genotype
-
Martin G.M., Sparague C.A., Epstein C.J. Replicative lifespan of cultivated human cells. Effects of dornor's age, tissue and genotype. Lab Invest. 23:1970;86-92.
-
(1970)
Lab Invest.
, vol.23
, pp. 86-92
-
-
Martin, G.M.1
Sparague, C.A.2
Epstein, C.J.3
-
25
-
-
0037066773
-
Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors
-
Mettenburg J.M., Webb D.J., Gonias S.L. Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors. J. Biol. Chem. 277:2002;13338-13345.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 13338-13345
-
-
Mettenburg, J.M.1
Webb, D.J.2
Gonias, S.L.3
-
26
-
-
0037040284
-
Regulation of cytosolic phospholipase A2 activity in macrophages stimulated with receptor-recognized forms of alpha 2-macroglobulin: Role in mitogenesis and cell proliferation
-
Misra U.K., Pizzo S.V. Regulation of cytosolic phospholipase A2 activity in macrophages stimulated with receptor-recognized forms of alpha 2-macroglobulin: role in mitogenesis and cell proliferation. J. Biol. Chem. 277:2002;4069-4078.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4069-4078
-
-
Misra, U.K.1
Pizzo, S.V.2
-
27
-
-
0027502881
-
Senescent WI-38 cells fail to express EPC-1, a gene induced in young cells upon entry into the G0 state
-
Pignolo R.J., Cristifalo V.J., Rotenberg M.O. Senescent WI-38 cells fail to express EPC-1, a gene induced in young cells upon entry into the G0 state. J. Biol. Chem. 268:1993;8949-8957.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 8949-8957
-
-
Pignolo, R.J.1
Cristifalo, V.J.2
Rotenberg, M.O.3
-
28
-
-
0027502881
-
Senescent WI-38 cells fail to express EPC-1, a gene induced in young cells upon entry into the G0 state
-
Pignolo R.J., Cristofalo V.J., Rotenberg M.O. Senescent WI-38 cells fail to express EPC-1, a gene induced in young cells upon entry into the G0 state. J. Biol. Chem. 268:1993;8949-8957.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 8949-8957
-
-
Pignolo, R.J.1
Cristofalo, V.J.2
Rotenberg, M.O.3
-
29
-
-
0032589297
-
Alpha2-macroglobulin enhances the clearance of endogenous soluble beta-amyloid peptide via low-density lipoprotein receptor-related protein in cortical neurons
-
Qiu Z., Strickland D.K., Hyman B.T., Rebeck G.W. Alpha2-macroglobulin enhances the clearance of endogenous soluble beta-amyloid peptide via low-density lipoprotein receptor-related protein in cortical neurons. J. Neurochem. 73:1999;1393-1398.
-
(1999)
J. Neurochem.
, vol.73
, pp. 1393-1398
-
-
Qiu, Z.1
Strickland, D.K.2
Hyman, B.T.3
Rebeck, G.W.4
-
30
-
-
0000299214
-
Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo
-
Rohme D. Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo. Proc. Natl Acad. Sci. USA. 78:1986;5009-5013.
-
(1986)
Proc. Natl Acad. Sci. USA
, vol.78
, pp. 5009-5013
-
-
Rohme, D.1
-
31
-
-
0020455613
-
Werner's syndromes: A review of recent research with analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations
-
Salk D. Werner's syndromes: a review of recent research with analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations. Hum. Genet. 62:1982;1-5.
-
(1982)
Hum. Genet.
, vol.62
, pp. 1-5
-
-
Salk, D.1
-
32
-
-
0024439479
-
The alpha-macroglobulin bait region. Sequence diversity and localization of cleavage sites for proteinases in five mammalian alpha-macroglobulins
-
Scottrup-Jensen L., Sand O., Kristensen L., Fey G.H. The alpha-macroglobulin bait region. Sequence diversity and localization of cleavage sites for proteinases in five mammalian alpha-macroglobulins. J. Biol. Chem. 264:1989;15781-15789.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 15781-15789
-
-
Scottrup-Jensen, L.1
Sand, O.2
Kristensen, L.3
Fey, G.H.4
-
33
-
-
0025052004
-
Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts
-
Seshadri T., Campisi J. Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts. Science. 247:1990;205-209.
-
(1990)
Science
, vol.247
, pp. 205-209
-
-
Seshadri, T.1
Campisi, J.2
-
34
-
-
0034713329
-
Is β-galactosidase staining a maker of senescence in vitro and in vivo
-
Severino J., Allen R.G., Balin S., Balin A., Cristifalo V.J. Is β-galactosidase staining a maker of senescence in vitro and in vivo. Exp. Cell Res. 257:2000;162-171.
-
(2000)
Exp. Cell Res.
, vol.257
, pp. 162-171
-
-
Severino, J.1
Allen, R.G.2
Balin, S.3
Balin, A.4
Cristifalo, V.J.5
-
35
-
-
0024541932
-
Regulation of collagenase and collagenase mRNA production in early and late-passage human diploid fibroblasts
-
Sottile J., Mann D.M., Diemer V., Millis A.J. Regulation of collagenase and collagenase mRNA production in early and late-passage human diploid fibroblasts. J. Cell Physiol. 138:1989;281-290.
-
(1989)
J. Cell Physiol.
, vol.138
, pp. 281-290
-
-
Sottile, J.1
Mann, D.M.2
Diemer, V.3
Millis, A.J.4
-
36
-
-
0028202945
-
Cell aging of human diploid fibroblasts is associated with changes in responsiveness to epidermal growth factor and changes in HER-2 expression
-
Tang Z.Q., Zhang Z.Y., Zheng Y., Corbley M.J., Tong T.J. Cell aging of human diploid fibroblasts is associated with changes in responsiveness to epidermal growth factor and changes in HER-2 expression. Mech. Ageing Dev. 73:1994;57-67.
-
(1994)
Mech. Ageing Dev.
, vol.73
, pp. 57-67
-
-
Tang, Z.Q.1
Zhang, Z.Y.2
Zheng, Y.3
Corbley, M.J.4
Tong, T.J.5
-
37
-
-
0033732110
-
Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes
-
Toussaint O., Medrano E.E., von Zglinicki T. Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes. Exp. Gerontol. 35:2000;927-945.
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 927-945
-
-
Toussaint, O.1
Medrano, E.E.2
Von Zglinicki, T.3
-
38
-
-
0036830475
-
From the Hayflick mosaic to the mosaics of ageing. Role of stress-induced premature senescence in human ageing
-
Toussaint O., Remacle J., Dierick J.F., Pascal T., Frippiat C., Zdanov S., Magalhaes J.P., Royer V., Chainiaux F. From the Hayflick mosaic to the mosaics of ageing. Role of stress-induced premature senescence in human ageing. Int. J. Biochem. Cell Biol. 34:2002;1415-1429.
-
(2002)
Int. J. Biochem. Cell Biol.
, vol.34
, pp. 1415-1429
-
-
Toussaint, O.1
Remacle, J.2
Dierick, J.F.3
Pascal, T.4
Frippiat, C.5
Zdanov, S.6
Magalhaes, J.P.7
Royer, V.8
Chainiaux, F.9
-
39
-
-
0033016225
-
Effects of donor age on the expression of a marker of replicative senescence (EPC-1) in human dermal fibroblasts
-
Tresini M., Pignolo R.J., Allen R.G., Cristifalo V.J. Effects of donor age on the expression of a marker of replicative senescence (EPC-1) in human dermal fibroblasts. J. Cell Physiol. 179:1999;11-17.
-
(1999)
J. Cell Physiol.
, vol.179
, pp. 11-17
-
-
Tresini, M.1
Pignolo, R.J.2
Allen, R.G.3
Cristifalo, V.J.4
-
40
-
-
0020366769
-
Age correlation of alpha-2-macroglobulin levels in healthy subjects
-
Wager V., Wagnerova M., Zvara K. Age correlation of alpha-2- macroglobulin levels in healthy subjects. Physiol. Bohemoslov. 31:1982;359-364.
-
(1982)
Physiol. Bohemoslov.
, vol.31
, pp. 359-364
-
-
Wager, V.1
Wagnerova, M.2
Zvara, K.3
|