Use of bioconversion for the preparation of [4-14C]-labeled 7α- and 7β-hydroxylated derivatives of dehydroepiandrosterone and epiandrosterone

Steroids

Volumn 67, Issue 13-14, 2002, Pages 1121-1127

  Chalbot, Sonia ^a   Trap, Catherine ^a   Monin, Jean Paul ^a   Morfin, Robert ^a  

^a Bioinformatique et Chimie Moléculaire   (France)

Author keywords

3 Hydroxysteroids; 7 Hydroxylation; 7 Hydroxylation; Crystallization; Steroid hormone

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ANDROSTANOLONE; ANDROSTERONE DERIVATIVE; CYTOCHROME; CYTOCHROME P450 7B1; EPIANDROSTERONE; PRASTERONE; RADIOISOTOPE; STEROID BINDING PROTEIN; UNCLASSIFIED DRUG; ANDROSTANEDIOL; ANDROSTERONE; CHOLESTEROL 7ALPHA MONOOXYGENASE; DRUG DERIVATIVE; HYDROXYSTEROID DEHYDROGENASE;

ARTICLE; BIOSYNTHESIS; BIOTRANSFORMATION; CHROMATOGRAPHY; COMAMONAS TESTOSTERONI; CONTROLLED STUDY; CRYSTALLIZATION; DILUTION; ESCHERICHIA COLI; HORMONE ACTION; HORMONE SYNTHESIS; ISOTOPE DILUTION ASSAY; ISOTOPE LABELING; MYCELIUM; NONHUMAN; RADIOACTIVITY; RHIZOPUS; STEROID METABOLISM; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROXYLATION; ISOLATION AND PURIFICATION; METABOLISM; PSEUDOMONAS;

COMAMONAS TESTOSTERONI; ESCHERICHIA COLI; PSEUDOMONAS; RHIZOPUS STOLONIFER;

ANDROSTANE-3,17-DIOL; ANDROSTERONE; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEHYDROEPIANDROSTERONE; ESCHERICHIA COLI; HUMANS; HYDROXYLATION; HYDROXYSTEROID DEHYDROGENASES; MOLECULAR STRUCTURE; PSEUDOMONAS; RHIZOPUS;

EID: 0036889680     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(02)00072-7     Document Type: Article

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