Fluorine-18 labelling of small interfering RNAs (siRNAs) for PET imaging

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 50, Issue 13, 2007, Pages 1159-1168

  Viel, Thomas ^a   Kuhnast, Bertrand ^a   Hinnen, Françoise ^a   Boisgard, Raphaël ^a   Tavitian, Bertrand ^a   Dollé, Frédéric ^a,b  

^a DIF   (France)

^b SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

Author keywords

Fluorine 18; FPyBrA; Oligonucleotide; siRNA

Indexed keywords

FLUORINE; FLUORINE COMPOUNDS; RNA;

COMPLEMENTARY SEQUENCES; FLUORINE-18; FPYBRA; LABELINGS; PET IMAGING; POSITRON EMITTERS; SHORT SEQUENCES; SIRNA; SMALL INTERFERING RNA; SPECIFIC ACTIVITY;

OLIGONUCLEOTIDES;

FLUORINE 18; LUCIFERASE; N [3 (2 FLUOROPYRIDIN 3 YLOXY)PROPYL] 2 BROMOACETAMIDE F 18; OLIGONUCLEOTIDE; RADIOISOTOPE; RADIOPHARMACEUTICAL AGENT; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL LABELING; DRUG CONJUGATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MACROMOLECULE; MOLECULAR IMAGING; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; RELATIVE DENSITY; RNA SEQUENCE;

EID: 38949161167     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1411     Document Type: Article

References (48)

1. Jorgensen RA, Cluster PD, English J, Que Q, Napoli CA. Plant Mol Biol 1996; 31: 957-973.
2. Napoli C, Lemieux C, Jorgensen R. Plant Cell 1990; 2: 279-289.
3. Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Nature 2001; 411: 494-498.
4. Tijsterman M, Retting RF, Plasterk RH. Annu Rev Genet 2002; 36: 489-519.
5. Filipowicz W. Cell 2005; 122: 17-20.
6. Hammond SM, Bernstein E, Beach D, Hannon GJ. Nature 2000; 404: 293-296.
7. Tang G. Trends Biochem Sci 2005; 30: 106-114.
8. Judge AD, Bola G, Lee AC, MacLachlan I. Mol Ther 2006; 13: 494-505.
9. Jackson AL, Burchard J, Leake D, Reynolds A, Schelter J, Guo J, Johnson JM, Lim L, Karpilow J, Nichols K, Marshall W, Khvorova A, Linsley PS. RNA 2006; 12: 1197-1205.
10. Hornung V, Guenthner-Biller M, Bourquin C, Ablasser A, Schlee M, Uematsu S, Noronha A, Manoharan M, Akira S, de Fougerolles A, Endres S, Hartmann G. Nat Med 2005; 11: 263-270.
11. Robbins MA, Rossi JJ. Nat Med 2005; 11: 250-251.
12. Sledz CA, Holko M, de Veer MJ, Silverman RH, Williams BR. Nat Cell Biol 2003; 5: 834-839.
13. Moss EG, Taylor JM. Nat Cell Biol 2003; 5: 771-772.
14. Braasch DA, Jensen S, Liu Y, Kaur K, Arar K, White MA, Corey DR. Biochemistry 2003; 42: 7967-7975.
15. Chiu YL, Rana TM. RNA 2003; 9: 1034-1048.
16. Tavitian B, Terrazzino S, Kuhnast B, Marzabal S, Stettler O, Dollé F, Deverre JR, Jobert A, Hinnen F, Bendriem B, Crouzel C, Di Giamberardino L. Nat Med 1998; 4: 467-471.
17. Kilbourn MR, Dence CS, Welch MJ, Mathias CJ. J Nucl Med 1987; 28: 462-470.
18. Wilbur DS. Bioconjug Chem 1992; 3: 433-470.
19. Okarvi SM. Eur J Nucl Med 2001; 28: 929-938.
20. de Bruin B, Kuhnast B, Hinnen F, Yaouancq L, Amessou M, Johannes L, Samson A, Boisgard R, Tavitian B, Dollé F. Bioconjug Chem 2005; 16: 406-420.
21. Kuhnast B, de Bruin B, Hinnen F, Tavitian B, Dollé F. Bioconjug Chem 2004; 15: 617-627.
22. Dolci L, Dollé F, Jubeau S, Vaufrey F, Crouzel C. J Label Compd Radiopharm 1999; 42: 975-985.
23. Karramkam M, Hinnen F, Vaufrey F, Dollé F. J Label Compd Radiopharm 2003; 46: 979-992.
24. Dollé F. Curr Pharm Des 2005; 11: 3221-3235.
25. 18F]Fluoropyridines: from conventional radiotracers to the labelling of macromolecules such as proteins and oligonucleotides. In PET Chemistry: The Driving Force in Molecular Imaging, Ernst Schering Research Foundation (ed.). Springer: Berlin, 2007; 113-157.
26. Kuhnast B, Klussmann S, Hinnen F, Boisgard R, Rousseau B, Fürste JP, Tavitian B, Dollé F. J Label Compd Radiopharm 2003; 46: 1205-1219.
27. Amarzguioui M, Holen T, Babaie E, Prydz H. Nucleic Acids Res 2003; 31: 589-595.
28. Czauderna F, Fechtner M, Dames S, Aygun H, Klippel A, Pronk GJ, Giese K, Kaufmann J. Nucleic Acids Res 2003; 31: 2705-2716.
29. Prakash TP, Allerson CR, Dande P, Vickers TA, Sioufi N, Jarres R, Baker BF, Swayze EE, Griffey RH, Bhat B. J Med Chem 2005; 48: 4247-4253.
30. Viel T, Boisgard R, Kuhnast B, Jego B, Siquier-Pernet K, Hinnen F, Dollé F, Tavitian B. Submitted.
31. Kuhnast B, Dollé F, Terrazzino S, Rousseau B, Loc'h C, Vaufrey F, Hinnen F, Doignon I, Pillon F, David C, Crouzel C, Tavitian B. Bioconjug Chem 2000; 11: 627-636.
32. Dollé F, Hinnen F, Vaufrey F, Tavitian B, Crouzel C. J Label Compd Radiopharm 1997; 39: 319-330.
33. Kuhnast B, Dollé F, Vaufrey F, Hinnen F, Crouzel C, Tavitian B. J Label Compd Radiopharm 2000; 43: 837-848.
34. Kuhnast B, Dollé F, Tavitian B. J Label Compd Radiopharm 2001; 45: 1-11.
35. Kuhnast B, Hinnen F, Boisgard R, Tavitian B, Dollé F. J Label Compd Radiopharm 2003; 46: 1093-1103.
36. Kuhnast B, Klussmann S, Hinnen F, Boisgard R, Rousseau B, Fürste JP, Tavitian B, Dollé F. J Label Compd Radiopharm 2003; 46: 1205-1219.
37. Hamzavi R, Dollé F, Tavitian B, Dahl O, Nielsen P. Bioconjug Chem 2003; 14: 941-954.
38. Kuhnast B, Hinnen F, Hamzavi R, Boisgard R, Tavitian B, Nielsen PE, Dollé F. J Label Compd Radiopharm 2005; 48: 51-61.
39. Marzabal S, Terrazzino S, Kuhnast B, Dollé F, Deverre JR, Jobert A, Crouzel C, Di Giamberardino L, Tavitian B. Nucleosides Nucleotides 1999; 18: 1731-1733.
40. Younes CK, Boisgard R, Tavitian B. Curr Pharm Des 2002; 8: 1451-1466.
41. Tavitian B, Marzabal S, Boutet V, Kuhnast B, Terrazzino S, Moynier M, Dollé F, Deverre JR, Thierry AR. Pharm Res 2002; 19: 367-376.
42. Tavitian B. Gut 2003; 52: 40-47.
43. Tavitian B. Oligonucleotides as radiopharmaceuticals. In Molecular Imaging, Ernst Schering Research Foundation (ed.). Springer: Berlin, 2004; 1-34.
44. Boisgard R, Kuhnast B, Vonhoff S, Younes C, Hinnen F, Verbavatz JM, Rousseau B, Fuerste JP, Wlotzka B, Dollé F, Klussmann S, Tavitian B. Eur J Nucl Med Mol Imaging 2005; 32: 470-477.
45. Coenen HH, Klatte B, Knoechel A, Schueller M, Stöcklin G. J Label Compd Radiopharm 1986; 23: 455-467.
46. Hamacher K, Coenen HH, Stöcklin G. J Nucl Med 1986; 27: 235-238.
47. Dollé F, Dolci L, Valette H, Hinnen F, Vaufrey F, Guenther I, Fuseau C, Coulon C, Bottlaender M, Crouzel C. J Med Chem 1999; 42: 2251-3698.
48. Dollé F, Valette H, Bottlaender M, Hinnen F, Vaufrey F, Guenther I, Crouzel C. J Label Compd Radiopharm 1998; 41: 451-463.