Gene expression induction of volatile organic compound and/or polycyclic aromatic hydrocarbon-metabolizing enzymes in isolated human alveolar macrophages in response to airborne particulate matter (PM2.5)

Toxicology

Volumn 244, Issue 2-3, 2008, Pages 220-230

  Saint Georges, Françoise ^a   Abbas, Imane ^b   Billet, Sylvain ^b   Verdin, Anthony ^b   Gosset, Pierre ^c   Mulliez, Philippe ^a   Shirali, Pirouz ^b   Garçon, Guillaume ^b  

^a Centre Hospitalier Saint Philibert GHICL   (France)

^b UNIVERSITÉ DU LITTORAL CÔTE D OPALE   (France)

^c UNIVERSITÉ CATHOLIQUE DE LILLE   (France)

Author keywords

Alveolar macrophage; Bronchoalveolar lavage; Cytotoxicity; Healthy outpatients; Metabolic activation; Particulate matter; Polycyclic aromatic hydrocarbons; Volatile organic compounds

Indexed keywords

CYTOCHROME P450 1A1; CYTOCHROME P450 2E1; ENZYME; GLUTATHIONE TRANSFERASE M3; GLUTATHIONE TRANSFERASE P1; OXIDOREDUCTASE; POLYCYCLIC AROMATIC COMPOUND; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE QUINONE OXIDOREDUCTASE 1; UNCLASSIFIED DRUG; VOLATILE ORGANIC COMPOUND;

AIR POLLUTION; AIRBORNE PARTICLE; ARTICLE; BRONCHOSCOPY; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; HUMAN; HUMAN CELL; LETHALITY; LUNG ALVEOLUS CELL; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; METABOLIC ACTIVATION; PARTICULATE MATTER; PRIORITY JOURNAL;

EID: 38949129386     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.11.016     Document Type: Article

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