Pro-inflammatory effects of Dunkerque city air pollution particulate matter 2.5 in human epithelial lung cells (L132) in culture

Journal of Applied Toxicology

Volumn 25, Issue 2, 2005, Pages 166-175

  Dagher, Zeina ^a   Garçon, Guillaume ^a   Gosset, Pierre ^b   Ledoux, Frédéric ^c   Surpateanu, Georgiana ^a   Courcot, Dominique ^d   Aboukais, Antoine ^d   Puskaric, Emile ^c   Shirali, Pirouz ^a  

^a UNIVERSITÉ DU LITTORAL CÔTE D OPALE   (France)

^b UNIVERSITÉ CATHOLIQUE DE LILLE   (France)

^c Lab Interdisc des Sci de Environ   (France)

^d UNIVERSITÉ DU LITTORAL CÔTE D OPALE   (France)

Author keywords

Cytotoxicity; GM CSF; IL 1 ; IL 6; IL 8; Inflammatory response; L132 cells; Physical and chemical characteristics; PM2.5; TGF 1; TNF

Indexed keywords

CYTOKINE; DIESEL FUEL; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

AIR POLLUTANT; AIR POLLUTION; ARTICLE; CITY; CONTROLLED STUDY; CYTOTOXICITY; EPITHELIUM CELL; FRANCE; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; MOTOR VEHICLE; OXIDATIVE STRESS; PARTICULATE MATTER; PRIORITY JOURNAL; PROTEIN SECRETION;

AIR POLLUTANTS; AIR POLLUTION; CELL SURVIVAL; CELLS, CULTURED; CITIES; CULTURE MEDIA; CYTOKINES; EPITHELIAL CELLS; FRANCE; GENE EXPRESSION; HUMANS; INFLAMMATION; PARTICLE SIZE;

EID: 16844368155     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jat.1050     Document Type: Article

References (53)

1. Alfaro-Moreno E, Martinez L, García-Cuellar C, Bonner JC, Murray JC, Rosas I, Ponce-de-Leon Rosales S, Miranda J, Osornio-Vargas AR. 2002. Biological effects induced in vitro by PM10 from three different zones of Mexico city. Environ. Health Perspect. 110: 715-720.
2. Baulig A, Sourdeval M, Meyer M, Marano F, Baeza-Squiban A. 2003. Biological effects of atmospheric particles on human bronchial epithelial cells. Comparison with diesel exhaust particles. Toxicol. In Vitro 17: 567-573.
3. Bayram H, Devalia JL, Sapsford RJ, Ohtoshi T, Miyabara Y, Sagai M, Davies RJ. 1998. The effect of diesel exhaust particles on cell function and release of inflammatory mediators from human bronchial epithelial cells in vitro. Am. J. Respir. Cell Mol. Biol. 18: 441-448.
4. Becher R, Hetland RB, Refsnes M, Dahl JE, Dahlman HJ, Schawarze PE. 2001. Rat lung inflammatory responses after in vivo and in vitro exposure to various stone particles. Inhal. Toxicol. 13: 789-805.
5. Becker S, Soukup JM, Gilmour MI, Delvin RB. 1996. Stimulation of human and rat alveolar macrophages by urban air particulates: effect on oxidant radical generation and cytokine production. Toxicol. Appl. Pharmacol. 141: 637-648.
6. Becker S, Soukup JM, Gilmour I, Devlin RB. 1997. Stimulation of human and rat alveolar macrophages by urban air particulates: effects on oxidant radical generation and cytokine production. Toxicol. Appl. Pharmacol. 141: 637-648.
7. Becker S, Soukup JM, Gallagher JR. 2002. Differential particulate air pollution induced oxidant stress in human granulocytes, monocytes and alveolar macrophages. Toxicol. In Vitro 16: 209-218.
8. Bellocq A, Azoulay E, Marulla S, Flahault A, Fouqueray B, Philippe C, Cadranel J, Baud L. 1999. Reactive oxygen and nitrogen intermediates increase transforming growth factor-beta 1 release from human epithelial alveolar cells through two different mechanisms. Am. J. Respir. Cell Mol. Biol. 21: 128-36.
9. Bergmann M, Barnes PJ, Newton R. 2000. Molecular regulation of granulocyte macrophage colony-stimulating factor in human lung epithelial cells by interleukin (IL)-1β, 1L-4, and IL-13 involves both transeriptional and post-transcriptional mechanisms. Am. J. Respir. Cell Mol. Biol. 22: 582-589.
10. Blackwell TS, Christman JW. 1997. The role of nuclear factor-κB in cytokine gene regulation. Am. J. Respir. Cell Mol. Biol. 17: 3-9.
11. Brunekreef B, Holgate S. 2002. Air pollution and health. Lancet 360: 1233-1242.
12. Diociaiuti M, Balduzzi M, De Berardis B, Cattiani G, Stacchini G, Ziemacki G, Marconi A, Paoletti L. 2001. The two PM(2.5) and PM(2.5-10) (coarse fractions: evidence of different biological activity. Environ. Res. 86: 254-262.
13. Dreher KL, Jaskot RH, Lehmann JR, Richards JH, McGee JK, Ohio AJ, Costa DL. 1997. Soluble transition metals mediate residual oil fly ash induced acute lung injury. J. Toxicol. Environ. Health 50: 285-305.
14. Driscoll KE. 2000. TNF-alpha and MIP-2: role in particle-induced inflammation and regulation by oxidative stress. Toxicol. Lett. 112/ 113: 177-183.
15. Dye JA, Adler KB, Richards JH, Dreher KL. 1999. Role of soluble metals in oil fly ash-induced airway epithelial injury and cytokine gene expression Am. J. Physiol. 277: L498-L510.
16. Englert N. 2004. Fine particle and human health - a review of epidemiological studies. Toxicol. Lett. 149: 235-242.
17. 5 and its use. US Patent 5,582,967, 10 Dec 1996.
18. Fujii T, Hayashi S, Hogg JC, Vincent R, Van Eeden SF. 2001. Particulate matter induces cytokine expression in human bronchial epithelial cells. Am. J. Respir. Cell Mol. Biol. 25: 265-271.
19. 3 particles: assessment of cellular membrane damage and antioxidant system disruption in human epithelial lung cells (L132) in culture. Toxicol. Lett. 117: 25-35.
20. 3 particles in human lung cells (A549). Toxicology 166: 129-137.
21. 3 particles-induced lung tissue injury: role of free radicals. Cancer Lett. 167: 7-15.
22. Garçon G, Ledoux F, Hannothiaux MH, Zerimech F, Puskaric E, Shirali P. 2002. Urban particulate air pollution and evaluation of its toxicity on human pulmonary cells in culture. In Proceedings of 6th International Aerosol Conference, Taiwan, 8-13 September 2002, Taiwan; 13.
23. Ghio AJ, Silbajoris R, Carson JL, Samet JM. 2002. Biological effects of oil fly ash. Environ. Health Perspect. 110: 89-94.
24. Harrison RM, Yin J. 2000. Particulate matter in the atmosphere: which particle properties are important for its effects on health? Sci. Total Environ. 249: 85-101.
25. Hetland RB, Refsnes M, Myran T, Johansen BV, Uthus N, Schwarze PE. 2000. Mineral and/or metal content as critical determinants of particle-induced release of IL-6 and IL-8 from A549 cells. J. Toxicol. Environ. Health A 60: 47-65.
26. Hetland RB, Myhre O, Lag M, Hongve D, Schawarze PE, Refsnes M. 2001. Importance of soluble metals and reactive oxygen species for cytokine release induced by mineral particles. Toxicology 165: 133-144.
27. Hetland RB, Cassee FR, Refsnes M, Schwarze PE, Lag M, Boere AJF, Dybing E. 2004. Release of inflammatory cytokines, cell toxicity and apoptosis in epithelial lung cells after exposure to ambient air particles of different size fractions. Toxicol In Vitro 18: 203-212.
28. Jimenez LA, Drost EM, Gilmour PS, Rahman I, Antonicelli F, Ritchie H, MacNee W, Donaldson K. 2002. PM(10)-exposed macrophages stimulate a proinflammatory response in lung epithelial cells via TNF-alpha. Am. J. Physiol. Lung. Cell Physiol. 282: L237-L248.
29. Kawasaki S, Takizawa H, Takami K, Desaki M, Okazaki H, Kasama T, Kobayashi K, Yamamoto K, Nakahara K, Tanaka M, Sagai M, Ohtoshi T. 2001. Benzene-extracted components are important for the major activity of diesel exhaust particles Effect on interleukin-8 gene expression in human bronchial epithelial cells. Am. J. Respir. Cell Mol. Biol. 24: 419-426.
30. Levy JI, Hammit JK, Spengler JD. 1999. Estimating the mortality impacts of particulate matter: what can be learned from between-study variability. Environ. Health Perspect. 108: 109-117.
31. Li N, Wang M, Oberley TD, Sempf JM, Nel AE. 2002. Comparison of the pro-oxidative and proinflammatory effects of organic diesel exhaust particle chemical in bronchial epithelial cells and macrophages. J. Immunol. 169: 4531-4541.
32. Liden J, Ek A, Palmberg L, Okret S, Larsson K. 2003. Organic dust activates NF-κB in lung epithelial cells. Respir. Med. 97: 882-892.
33. McRitchie DI, Isowa N, Edelson JD, Xavier AM, Cai L, Man HY, Wang YT, Keshavjee SH, Slutsky AS, Liu M. 2000. Production of tumour necrosis factor alpha by primary cultured rat alveolar epithelial cells. Cytokine 12: 644-654.
34. Monn C, Becker S. 1999. Cytotoxicity and induction of proinflammatory cytokines from human monocytes exposed to fine (PM2.5) and coarse particles (PM10-2.5) in outdoor and indoor air. Toxicol. Appl. Pharmacol. 155: 245-252.
35. Nel AE, Diaz-Sanchez D, Li N. 2001. The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress. Curr. Opin. Pulm. Med. 7: 20-26.
36. Newton R, Staples KJ, Hart L, Barnes PJ, Bergmann MW. 2001. GMCSF expression in pulmonary epithelial cells is regulated negatively by posttranscriptional mechanisms. Biachem. Biophys. Res. Commun 287: 249-253.
37. Osornio-Vargas AR, Bonner JC, Alfaro-Moreno E, Martinez L, Garcia-Cuellar C, Ponce-de-Leon Rosales S, Miranda J, Rosas I. 2003. Proinflammatory and cytotoxic effects of Mexico city air pollution particulate matter in vitro are dependent on particle size and composition. Environ. Health Perspect. 111: 1289-1295.
38. 10 pollution on pulmonary function of smokers with mild to moderate chronic obstructive pulmonary disease. Am. Rev. Respir. Dis. 147: 1336-1340.
39. Pozzi R, De Berardis B, Paoletti L, Guastadisegni C. 2003. Inflammatory mediators induced by coarse (PM2.5-1) and fine (PM2.5) urban air particles in RAW 2647 cells. Toxicology 183: 243-254.
40. Rahman I, MacNee W. 2000. Oxidative stress and regulation of glutathione in lung inflammation. Eur. Respir. J. 16: 534-554.
41. Schins RP, Kanaapen AM, Weishaupt C, Winzer A, Borm PJA. 2002. Cytotoxic and inflammatory effects of coarse and fine particulate matter in macrophages and epithelial cells. Ann. Occup. Hyg. 46: 203-206.
42. Schwartz J, Slater D, Larson TV, Pierson WE, Koenig JQ. 1993. Particulate air pollution and hospital emergency room visits for asthma in Seattle. Am. Rev. Respir. Dis. 147: 826-831.
43. 2 on arachidonic acid metabolites in cultured human lung cells (L132 cell line). Carcinogenesis 15: 759-762.
44. 3), benzo(a)pyrene and pyrene and analysis of particles by Laser Microprobe Mass Analyser (in-vitro) [abstract]. Cell Biol. Toxicol. 11: 215.
45. Shukla A, Timblin C, BeruBe K, Gordon T, McKinney W, Driscoll K, Vacek P, Mossman BT. 2000. Inhaled particulate matter causes expression of nuclear factor (NF)-κB-related genes and oxidant-dependent NF-κB activation in vitro. Am. J. Respir. Cell Mol. Biol. 23: 182-187.
46. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Klenk DC. 1989. Measurement of protein using bicinchoninic acid. Anal. Biochem. 120: 76-85.
47. Spurny KR. 1998. On the physics, chemistry and toxicology of ultrafine anthropogenic, atmospheric aerosols (UAAA): new advances. Toxicol. Lett. 97: 253-261.
48. Takizawa H, Ohtoshi T, Kawasaki S, Kohyama T, Desaki M, Kasama T, Kobayashi K, Nakahara K, Yamamoto K, Matsushima K, Kudoh S. 1999. Diesel exhaust particles induce NF-κB activation in human bronchial epithelial cells in-vitro: importance in cytokine transcription. J. Immunol. 162: 4705-4711.
49. Tao F, Gonzalez-Flecha B, Kobzik L. 2003. Reactive oxygen species in pulmonary inflammation by ambient particulates. Free Rad. Biol. Med. 35: 327-340.
50. Van Eeden SF, Tan WC, Suwa T, Mukae H, Terashima T, Fujii T, Qui D, Vincent R, Hogg JC. 2001. Cytokines involved in the systemic inflammatory response induced by exposure to particulate matter air pollutants (PM(10)). Am. J. Respir. Crit. Care. Med. 164: 826-830.
51. Warshamana GS, Corti M, Brody AR. 2001. TNF-alpha, PDGF, and TGF-beta(1) expression by primary mouse bronchiolar-alveolar epithelial and mesenchymal cells: tnf-alpha induces TGF-beta(1). Exp. Mol. Pathol. 71: 13-33.
52. Winyard PG, Blake DR. 1997. Antioxidant, redox-regulated transcription factors, and inflammation. Adv. Pharmacol. 38: 403-421.
53. Yoshida Y, Maruyama M, Fujita T, Arai N, Hayashi R, Araya J, Matsui S, Yamashita N, Sugiyama E, Kobayashi M. 1999. Reactive oxygen intermediates stimulate interleukin-6 production in human bronchial epithelial cells. Am. J. Physiol. 276: L900-L908.