Altered Ca2+ homeostasis in lymphoblasts from patients with late-onset Alzheimer disease

Alzheimer Disease and Associated Disorders

Volumn 11, Issue 4, 1997, Pages 220-227

  Ibarreta, Dolores ^a   Parrilla, Roberto ^a   Ayuso, Matilde Sánchez ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

amyloid peptide; Anti immunoglobulin M; Calcium (Ca2+) replenishment; Cytosolic free Ca2+ ; Lymphoblasts

Indexed keywords

AMYLOID BETA PROTEIN; CALCIUM ION; IMMUNOGLOBULIN M ANTIBODY; PEPTIDE FRAGMENT; CALCIUM;

ADULT; AGED; AGING; ALZHEIMER DISEASE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOSOL; FEMALE; HUMAN; HUMAN CELL; LYMPHOBLAST; MALE; ONSET AGE; PRIORITY JOURNAL; CELL AGING; HOMEOSTASIS; KINETICS; LYMPHOCYTE; METABOLISM; PATHOLOGY; PHYSIOLOGY; REFERENCE VALUE; REVIEW;

AGE OF ONSET; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CALCIUM; CELL AGING; CYTOSOL; FEMALE; HOMEOSTASIS; HUMANS; KINETICS; LYMPHOCYTES; MALE; PEPTIDE FRAGMENTS; REFERENCE VALUES;

EID: 0031283149     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Aman P, Ehlin-Henriksson B, Klein G. Epstein-Barr virus susceptibility of normal human B lymphocyte populations. J Exp Med 1984;159:208-20.
2. Arispe N, Pollard HB, Rojas E. Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayermembranes. Proc Natl Acad Sci USA 1993a;90:10573-7.
3. Arispe N, Rojas E, Pollard HB. Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum. Proc Natl Acad Sci USA 1993b;90:567-71.
4. Boyum A. Isolation of mononuclear cells and granulocytes from human blood: isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest 1968;21(suppl 97):77-89.
5. Cambier JC, Ransom JT. Molecular mechanisms of transmembrane signaling in B lymphocytes. Annu Rev Immunol 1987;5:175-99.
6. 2+ pump of the plasma membrane. J Biol Chem 1992;267:2115-8.
7. Choi DW. Ionic dependence of glutamate neurotoxicity. J Neurosci 1987;7:369-79.
8. Corder EH, Saunders AM, Strittmatter WJ, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993;261:921-3.
9. Eckert A, Förstl H, Hartmann H, et al. The amplifying effect of β-amyloid on cellular calcium signalling is reduced in Alzheimer's disease. Clin Neurosci Neuropsychol 1995;6:1199-202.
10. Eckert A, Hartmann H, Müller WE. Beta-amyloid protein enhances the mitogen-induced calcium response in circulating human lymphocytes. FEBS Lett 1993;330:49-52.
11. Emre M, Geula C, Ransil BJ, Mesulam M-M. The acute neurotoxicity and effects upon cholinergic axons of intracerebrally injected beta-amyloid in the rat brain. Neurobiol Aging 1992;13:553-9.
12. Engström I, Ronquist G, Petterson L, Waldenström A. Alzheimer amyloid β-peptides exhibit ionophore-like properties in human erythrocytes. Eur J Clin Invest 1995;25:471-6.
13. Föhr UG, Gibson GE, Tofel-Grehl B, Schäfer BW, Heizman CW. Expression of intracellular calcium-binding proteins in cultured skin fibroblasts from Alzheimer and normal aged donors. Biochem Biophys Acta 1994;1223:391-7.
14. Folstein MF, Folstein SE, McHugh PR. "Mini-Mental State": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-98.
15. García ML, King VF, Shevell JL, et al. Amiloride analogs inhibit L-type calcium channels and display calcium entry blocker activity. J Biol Chem 1990;265:3763-71.
16. Gibson GE, Toral-Barza L. Cytosolic free calcium in lymphoblasts from young, aged and Alzheimer subjects. Mech Ageing Dev 1992;63:1-9.
17. Glenner GG, Wong CW. Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem Biophys Res Commun 1984;120:885-90.
18. Goate A, Chartier-Harlin MC, Mullan M, et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 1991;349:704-6.
19. Gorevic PD, Goni F, Pons-Estel B, Alvarez F, Peress NS, Frangione B. Isolation and partial characterization of neurofibrillary tangles and amyloid plaque core in Alzheimer's disease: immunohistological studies. J Neuropathol Exp Neurol 1986;45:647-64.
20. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985;260:3440-50.
21. Hartmann H, Eckert A, Müller WE. Beta-amyloid protein amplifies calcium signalling in central neurons from the adult mouse. Biochem Biophys Res Commun 1993;194:1216-20.
22. Heizmann CW, Braun K. Changes in Ca(2+)-binding proteins in human neurodegenerative disorders. Trends Neurosci 1992;15:259-64.
23. Hendriks L, van Duijn CM, Cras P, et al. Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene. Nature Genet 1992;1:218-21.
24. Joachim CL, Duffy LK, Morris JH, Selkoe DJ. Protein chemical and immunocytochemical studies of meningovascular beta-amyloid protein in Alzheimer's disease and normal aging. Brain Res 1988;474:100-11.
25. Joseph R, Han E. Amyloid beta-protein fragment 25-35 causes activation of cytoplasmic calcium in neurons. Biochem Biophys Res Commun 1992;184:1441-7.
26. Kang J, Lemaire HG, Unterbeck A, et al. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 1987;325:733-6.
27. Khachaturian ZS. Calcium regulations: final common pathway for age associated neurodegenerative processes. Neurosci Res Commun 1993;13:s3-6.
28. Kowall NW, Beal MF, Busciglio J, Duffy LK, Yankner BA. An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P. Proc Natl Acad Sci USA 1991;88:7247-51.
29. Masters CL, Simms G, Weinman NA, Multhaup G, McDonald BL, Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci USA 1985;82:4245-9.
30. Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I, Rydel RE. Beta-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 1992;12:376-89.
31. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 1984;34:939-44.
32. Mullan M, Crawford F, Axelman K, et al. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid. Nature Genet 1992;1:345-7.
33. Murrell J, Farlow M, Ghetti B, Benson MD. A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease. Science 1991;254:97-9.
34. Namba Y, Tomonaga M, Kawasaki H, Otomo E, Ikeda K. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res 1991;541:163-6.
35. Ounanian A, Guilbert B, Seigneurin J-M. Characteristics of Epstein-Barr virus transformed B cell lines from patients with Alzheimer's disease and age-matched controls. Mech Ageing Dev 1992;63:105-16.
36. Peterson C, Ratan RR, Shelanski ML, Goldman JE. Cytosolic free calcium and cell spreading decrease in fibroblasts from aged and Alzheimer donors. Proc Natl Acad Sci USA 1986;83:7999-8001.
37. Pike CJ, Burdick D, Walencewicz AJ, Glabe CG, Cotman CW. Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state. J Neurosci 1993;13:1676-87.
38. Pike CJ, Walencewicz AJ, Glabe CG, Cotman CW. In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity Brain Res 1991;563:311-4.
39. Saunders AM, Schmader K, Breitner JC, et al. Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases. Lancet 1993;342:710-1.
40. Siesjo BK. Cell damage in the brain: a speculative synthesis. J Cereb Blood Flow Metab 1981;1:155-85.
41. Tosato G, Blaese RM, Yarchoan R. Relationship between immunoglobulin production and immortalization by Epstein Barr virus. J Immunol 1985;135:959-64.
42. Van Eldik LJ, Griffin WST. S100 beta expression in Alzheimer's disease: relation to neuropathology in brain regions. Biochem Biophys Acta 1994;1223:398-403.
43. Walls EV, Crawford DH. Generation of human B lymphoblastoid cell lines using Epstein-Barr virus. In: Klaus GGB, ed. Lymphocytes, a practical approach. Oxford, UK: IRL Press Ltd., 1987:149-62.
44. Wisniewski T, Frangione B. Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid. Neurosci Lett 1992;135:235-8.
45. Yankner BA, Duffy LK, Kirschner DA. Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science 1990;250:279-82.