Calcium responses in human fibroblasts: A diagnostic molecular profile for Alzheimer's disease

Neurobiology of Aging

Volumn 17, Issue 4, 1996, Pages 549-555

  Hirashima, Naohide ^a   Etcheberrigaray, René ^a,e   Bergamaschi, Stefania ^b   Racchi, Marco ^c   Battaini, Fiorenzo ^b   Binetti, Giuliano ^c   Govoni, Stefano ^d   Alkon, Daniel L ^a,f  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b UNIVERSITY OF MILAN   (Italy)

^c Sacred Heart Hospital FBF   (Italy)

^d UNIVERSITY OF PAVIA   (Italy)

^e GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^f NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Alzheimer's disease; Bombesin; Bradykinin; Calcium; Fibroblast; TEA

Indexed keywords

CALCIUM CHANNEL;

ALZHEIMER DISEASE; ARTICLE; CALCIUM METABOLISM; CALCIUM TRANSPORT; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

EID: 0029787370     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/0197-4580(96)00074-7     Document Type: Article

References (13)

1. Adunsky, A.; Baram, D.; Hershokowitz, M.; Mekori, Y. A. Increased cytosolic free calcium in lymphocytes of Alzheimer patients. J. Neuroimmunol. 33:167-172; 1991.
2. Alkon, D. L. Memory traces in the brain. New York: Cambridge Univ. Press; 1987.
3. Alkon, D. L. Memory storage and neural systems. Sci. Am. 261:42-50; 1989.
4. Alkon, D. L. Memory's voice. New York: Harper Collins; 1992.
5. Baker, A. C.; Ko, L.-W.; Blass, J. P. Systemic manifestations of Alzheimer's disease. Age 11:60-65; 1988.
6. Bergamaschi, S.; Racchi, M.; Battaini, F.; Trabucchi, M.; Bianchetti, A.; Binetti, G.; Govoni, S. Protein kinase C regulates ß-amyloid precursor secretion in fibroblasts from control and Alzheimer's disease patients. Soc. Neurosci. Abstr. 20:849; 1994.
7. + channels in olfactory neuroblasts from Alzheimer's and normal donors. Soc. Neurosci. Abstr. 20:1673a; 1994.
8. 2+] in mononuclear blood cells from demented patients and healthy controls. Eur. Arch. Psychiatr. Clin. Neurosci. 243:224-228; 1994.
9. i transients are similar in fibroblasts from normal and Alzheimer's donors. Neurobiol. Aging 13:33-38; 1991.
10. Boucher, R. Cystic fibrosis. In: Isselbacher, K. S; Brauwald, E.; Wilson, J. D.; Martin, J. B.; Fauci, A. S.; Kasper, D. L., eds. Harrison's principles of internal medicine, 13th ed. New York: McGraw-Hill, Inc.; 1994:1194-1197.
11. Burch, R. M.; Kyle, D. J. Recent developments in the understanding of bradykinin receptors. Life Sci. 50:829-838; 1992.
12. Etcheberrigaray, R.; Gibson, G. E.; Alkon, D. L. Molecular mechanism of memory and the pathophysiology of Alzheimer's disease. Ann. NY Acad. Sci. 747:245-255; 1994.
13. Etcheberrigaray, R.; Ito, E.; Oka, K.; Tofel-Grehl, B.; Gibson, G. E.; Alkon, D. L. Potassium channel dysfunction in fibroblasts identifies patients with Alzheimer disease. Proc. Natl. Acad. Sci. USA 90:8209-8213; 1993.