Inhibition of alanyl-aminopeptidase on CD4+CD25+ regulatory T-cells enhances expression of FoxP3 and TGF-β1 and ameliorates acute colitis in mice

International Journal of Molecular Medicine

Volumn 20, Issue 4, 2007, Pages 483-492

  Bank, Ute ^a   Tadje, Janine ^b   Täger, Michael ^a   Wolke, Carmen ^b   Bukowska, Alicja ^b   Ittenson, Annelore ^b   Reinhold, Dirk ^b   Helmuth, Martin ^a   Ansorge, Siegfried ^a   Shakespeare, Ann ^b   Vieth, Michael ^c   Malfertheiner, Peter ^b   Naumann, Michael ^b   Lendeckel, Uwe ^b  

^a IMTM GmbH   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c INSTITUTE OF PATHOLOGY   (Germany)

Author keywords

Autoimmunity; Experimental colitis; Immune regulation; Inflammatory bowel disease; Transforming growth factor 1

Indexed keywords

CD4 ANTIGEN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; INTERLEUKIN 2 RECEPTOR ALPHA; MESSENGER RNA; MICROSOMAL AMINOPEPTIDASE; OLIGOPEPTIDE; PHEBESTIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; COLITIS; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; PATHOLOGY; PHENOTYPE; REGULATORY T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD13; ANTIGENS, CD4; COLITIS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HUMANS; IMMUNE TOLERANCE; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; OLIGOPEPTIDES; PHENOTYPE; RNA, MESSENGER; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA1;

EID: 38449121335     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.20.4.483     Document Type: Article

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