Recent developments in structure-activity relationships for steroid modulators of GABAA receptors

Brain Research Reviews

Volumn 37, Issue 1-3, 2001, Pages 91-97

  Covey, Douglas F ^a   Evers, Alex S ^a   Mennerick, Steven ^a   Zorumski, Charles F ^a   Purdy, Robert H ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Benz e indenes; Functional modulation; Intravenous anesthetic; Ligand gated ion channels; Neuroactive steriod; Neurosteroid enantiomer

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 3ALPHA HYDROXY 5BETA PREGNAN 20 ONE SULFATE; 4 AMINOBUTYRIC ACID A RECEPTOR; ALFAXALONE; BENZ[E]INDENE DERIVATIVE; ELTANOLONE; INDENE DERIVATIVE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROSTEROID; PREGNENOLONE SULFATE; STEROID RECEPTOR; STERYL SULFATASE; UNCLASSIFIED DRUG;

BINDING SITE; CONFERENCE PAPER; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG STRUCTURE; ENANTIOMER; GABAERGIC SYSTEM; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; RECEPTOR DENSITY; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING SITES; HUMANS; RECEPTORS, GABA-A; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP; SYNAPTIC TRANSMISSION;

EID: 0035666443     PISSN: 01650173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0173(01)00126-6     Document Type: Conference Paper

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