Structure-activity relationship of hydroxamate-based inhibitors on membrane-bound Fas ligand and TNF-α processing

Drug Design and Discovery

Volumn 16, Issue 2, 1999, Pages 119-130

  Yamamoto, Minoru ^a   Hirayama, Ryoichi ^a   Naruse, Kiyoshi ^a   Yoshino, Koichiro ^a   Shimada, Akemi ^a   Inoue, Shintaro ^a   Kayagaki, Nobuhiko ^b   Yagita, Hideo ^b   Okumura, Ko ^b   Ikeda, Shoji ^a  

^a KANEBO LTD   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

Author keywords

Fas ligand; Hydroxamic acid; Processing inhibitor; Structure activity relationship; TNF

Indexed keywords

COLLAGENASE; COMPLEMENTARY DNA; FAS LIGAND; GELATINASE B; HYDROXAMIC ACID DERIVATIVE; LIPOPOLYSACCHARIDE; MATRIX METALLOPROTEINASE INHIBITOR; MEMBRANE PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; DRUG MECHANISM; HELPER CELL; PROTEIN PROCESSING; STRUCTURE ACTIVITY RELATION;

ANTIGENS, CD95; HUMANS; HYDROXAMIC ACIDS; LIPOPOLYSACCHARIDES; METALLOENDOPEPTIDASES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 6544234671     PISSN: 10559612     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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