Amyloid β-peptide 31-35-induced neuronal apoptosis is mediated by caspase-dependent pathways via cAMP-dependent protein kinase A activation

Aging Cell

Volumn 7, Issue 1, 2008, Pages 47-57

  Zhao, Li ^a,b,d   Qian, Zhong Ming ^b,d   Zhang, Ce ^b   Wing, Ho Yung ^c   Du, Fang ^c   Ya, Ke ^c  

^a BEIJING SPORT UNIVERSITY   (China)

^b SHANXI MEDICAL UNIVERSITY   (China)

^c Prince of Wales Hospital   (Hong Kong)

^d HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Amyloid peptide 31 35 (A 31 35 ); Apoptosis; Caspase dependent intrinsic and extrinsic pathways; Cortical neurons; Group III metabotropic glutamate receptors (mGluRs); Neuroprotection; PKA dependent pathway

Indexed keywords

4 PHOSPHONOPHENYLGLYCINE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[31-35]; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; METABOTROPIC RECEPTOR; PHOSPHOSERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; ENZYME ACTIVITY; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GLYCINE; IN SITU NICK-END LABELING; NEURONS; PEPTIDE FRAGMENTS; PHOSPHOSERINE; PREFRONTAL CORTEX; PROTEIN KINASE INHIBITORS; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; SIGNAL TRANSDUCTION;

EID: 38349179703     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2007.00352.x     Document Type: Article

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