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Volumn 97, Issue 1, 2008, Pages 433-454

Liposomal delivery of hydrophobic weak acids: Enhancement of drug retention using a high intraliposomal pH

Author keywords

Cancer chemotherapy; Controlled delivery; Controlled release; Formulation; Liposomes; Mathematical model; Nanoparticles; Passive diffusion transport; Permeability; Phospholipids

Indexed keywords

CAMPTOTHECIN; DB 67; UNCLASSIFIED DRUG;

EID: 38349106839     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21135     Document Type: Article
Times cited : (26)

References (57)
  • 1
    • 0035120280 scopus 로고    scopus 로고
    • Stealth liposomes and tumor targeting: One step further in the quest for the magic bullet
    • Gabizon AA. 2001. Stealth liposomes and tumor targeting: one step further in the quest for the magic bullet. Clin Cancer Res 7:223-225.
    • (2001) Clin Cancer Res , vol.7 , pp. 223-225
    • Gabizon, A.A.1
  • 2
    • 0036875493 scopus 로고    scopus 로고
    • Liposomal drug carrier systems in cancer chemotherapy: Current status and future prospects
    • Gabizon AA. 2002. Liposomal drug carrier systems in cancer chemotherapy: current status and future prospects. J Drug Target 10:535-538.
    • (2002) J Drug Target , vol.10 , pp. 535-538
    • Gabizon, A.A.1
  • 3
    • 0038011874 scopus 로고    scopus 로고
    • Emerging role of liposomal drug carrier systems in cancer chemotherapy
    • Gabizon A. 2003. Emerging role of liposomal drug carrier systems in cancer chemotherapy. J Liposome Res 13:17-20.
    • (2003) J Liposome Res , vol.13 , pp. 17-20
    • Gabizon, A.1
  • 4
    • 0037681850 scopus 로고    scopus 로고
    • Pharmacokinetics of pegylated liposomal Doxorubicin: Review of animal and human studies
    • Gabizon A, Shmeeda H, Barenholz Y. 2003. Pharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studies. Clin Pharmacokinet 42:419-436.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 419-436
    • Gabizon, A.1    Shmeeda, H.2    Barenholz, Y.3
  • 5
    • 0035005359 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin: Metamorphosis of an old drug into a new form of chemotherapy
    • Gabizon AA. 2001. Pegylated liposomal doxorubicin: metamorphosis of an old drug into a new form of chemotherapy. Cancer Invest 19:424-436.
    • (2001) Cancer Invest , vol.19 , pp. 424-436
    • Gabizon, A.A.1
  • 7
    • 2142649179 scopus 로고    scopus 로고
    • An evaluation of transmembrane ion gradient-mediated encapsulation of topotecan within liposomes
    • Abraham SA, Edwards K, Karlsson G, Hudon N, Mayer LD, Bally MB. 2004. An evaluation of transmembrane ion gradient-mediated encapsulation of topotecan within liposomes. J Control Release 96: 449-461.
    • (2004) J Control Release , vol.96 , pp. 449-461
    • Abraham, S.A.1    Edwards, K.2    Karlsson, G.3    Hudon, N.4    Mayer, L.D.5    Bally, M.B.6
  • 12
    • 0032508857 scopus 로고    scopus 로고
    • Ionophore-mediated uptake of ciprofloxacin and vincristine into large unilamellar vesicles exhibiting transmembrane ion gradients
    • Fenske DB, Wong KF, Maurer E, Maurer N, Leenhouts JM, Boman N, Amankwa L, Cullis PR. 1998. Ionophore-mediated uptake of ciprofloxacin and vincristine into large unilamellar vesicles exhibiting transmembrane ion gradients. Biochim Biophys Acta 1414:188-204.
    • (1998) Biochim Biophys Acta , vol.1414 , pp. 188-204
    • Fenske, D.B.1    Wong, K.F.2    Maurer, E.3    Maurer, N.4    Leenhouts, J.M.5    Boman, N.6    Amankwa, L.7    Cullis, P.R.8
  • 13
    • 33749073801 scopus 로고    scopus 로고
    • Remote loading of doxorubicin into liposomes driven by a transmembrane phosphate gradient
    • Fritze A, Hens F, Kimpfler A, Schubert R, Peschka-Suss R. 2006. Remote loading of doxorubicin into liposomes driven by a transmembrane phosphate gradient. Biochim Biophys Acta 1758:1633-1640.
    • (2006) Biochim Biophys Acta , vol.1758 , pp. 1633-1640
    • Fritze, A.1    Hens, F.2    Kimpfler, A.3    Schubert, R.4    Peschka-Suss, R.5
  • 14
    • 0027514941 scopus 로고
    • Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases
    • Haran G, Cohen R, Bar LK, Barenholz Y. 1993. Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochim Biophys Acta 1151:201-215.
    • (1993) Biochim Biophys Acta , vol.1151 , pp. 201-215
    • Haran, G.1    Cohen, R.2    Bar, L.K.3    Barenholz, Y.4
  • 15
    • 0037014697 scopus 로고    scopus 로고
    • A versatile prodrug approach for liposomal core-loading of water-insoluble camptothecin anticancer drugs
    • Liu X, Lynn BC, Zhang J, Song L, Bom D, Du W, Curran DP, Burke TG. 2002. A versatile prodrug approach for liposomal core-loading of water-insoluble camptothecin anticancer drugs. J Am Chem Soc 124:7650-7651.
    • (2002) J Am Chem Soc , vol.124 , pp. 7650-7651
    • Liu, X.1    Lynn, B.C.2    Zhang, J.3    Song, L.4    Bom, D.5    Du, W.6    Curran, D.P.7    Burke, T.G.8
  • 17
    • 0032898738 scopus 로고    scopus 로고
    • Factors influencing uptake and retention of amino-containing drugs in large unilamellar vesicles exhibiting transmembrane pH gradients
    • Maurer-Spurej E, Wong KF, Maurer N, Fenske DB, Cullis PR. 1999. Factors influencing uptake and retention of amino-containing drugs in large unilamellar vesicles exhibiting transmembrane pH gradients. Biochim Biophys Acta 1416: 1-10.
    • (1999) Biochim Biophys Acta , vol.1416 , pp. 1-10
    • Maurer-Spurej, E.1    Wong, K.F.2    Maurer, N.3    Fenske, D.B.4    Cullis, P.R.5
  • 18
    • 33845368651 scopus 로고    scopus 로고
    • Transition metal-mediated liposomal encapsulation of irinotecan (CPT-11) stabilizes the drug in the therapeutically active lactone conformation
    • Ramsay E, Alnajim J, Anantha M, Taggar A, Thomas A, Edwards K, Karlsson G, Webb M, Bally M. 2006. Transition metal-mediated liposomal encapsulation of irinotecan (CPT-11) stabilizes the drug in the therapeutically active lactone conformation. Pharm Res 23:2799-2808.
    • (2006) Pharm Res , vol.23 , pp. 2799-2808
    • Ramsay, E.1    Alnajim, J.2    Anantha, M.3    Taggar, A.4    Thomas, A.5    Edwards, K.6    Karlsson, G.7    Webb, M.8    Bally, M.9
  • 21
    • 29244439986 scopus 로고    scopus 로고
    • Formation of drug-arylsulfonate complexes inside liposomes: A novel approach to improve drug retention
    • Zhigaltsev IV, Maurer N, Edwards K, Karlsson G, Cullis PR. 2006. Formation of drug-arylsulfonate complexes inside liposomes: a novel approach to improve drug retention. J Control Release 110: 378-386.
    • (2006) J Control Release , vol.110 , pp. 378-386
    • Zhigaltsev, I.V.1    Maurer, N.2    Edwards, K.3    Karlsson, G.4    Cullis, P.R.5
  • 22
    • 0036304427 scopus 로고    scopus 로고
    • Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins
    • Garcia-Carbonero R, Supko JG. 2002. Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins. Clin Cancer Res 8:641-661.
    • (2002) Clin Cancer Res , vol.8 , pp. 641-661
    • Garcia-Carbonero, R.1    Supko, J.G.2
  • 23
    • 0038167666 scopus 로고    scopus 로고
    • The camptothecins
    • Pizzolato JF, Saltz LB. 2003. The camptothecins. Lancet 361:2235-2242.
    • (2003) Lancet , vol.361 , pp. 2235-2242
    • Pizzolato, J.F.1    Saltz, L.B.2
  • 24
    • 0036399299 scopus 로고    scopus 로고
    • Camptothecins: A review of their chemotherapeutic potential
    • Ulukan H, Swaan PW. 2002. Camptothecins: a review of their chemotherapeutic potential. Drugs 62:2039-2057.
    • (2002) Drugs , vol.62 , pp. 2039-2057
    • Ulukan, H.1    Swaan, P.W.2
  • 26
    • 0027096415 scopus 로고
    • A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues
    • Fassberg J, Stella VJ. 1992. A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues. J Pharm Sci 81:676-684.
    • (1992) J Pharm Sci , vol.81 , pp. 676-684
    • Fassberg, J.1    Stella, V.J.2
  • 27
    • 0027201885 scopus 로고
    • Preferential binding of the carboxylate form of camptothecin by human serum albumin
    • Burke TG, Mi Z. 1993. Preferential binding of the carboxylate form of camptothecin by human serum albumin. Anal Biochem 212:285-287.
    • (1993) Anal Biochem , vol.212 , pp. 285-287
    • Burke, T.G.1    Mi, Z.2
  • 28
    • 0028012774 scopus 로고
    • The structural basis of camptothecin interactions with human serum albumin: Impact on drug stability
    • Burke TG, Mi Z. 1994. The structural basis of camptothecin interactions with human serum albumin: impact on drug stability. J Med Chem 37:40-46.
    • (1994) J Med Chem , vol.37 , pp. 40-46
    • Burke, T.G.1    Mi, Z.2
  • 29
    • 0027930186 scopus 로고
    • Differential interactions of camptothecin lactone and carboxylate forms with human blood components
    • Mi Z, Burke TG. 1994. Differential interactions of camptothecin lactone and carboxylate forms with human blood components. Biochemistry 33:10325-10336.
    • (1994) Biochemistry , vol.33 , pp. 10325-10336
    • Mi, Z.1    Burke, T.G.2
  • 30
    • 0028150946 scopus 로고
    • Marked interspecies variations concerning the interactions of camptothecin with serum albumins: A frequency-domain fluorescence spectroscopic study
    • Mi Z, Burke TG. 1994. Marked interspecies variations concerning the interactions of camptothecin with serum albumins: a frequency-domain fluorescence spectroscopic study. Biochemistry 33:12540-12545.
    • (1994) Biochemistry , vol.33 , pp. 12540-12545
    • Mi, Z.1    Burke, T.G.2
  • 31
    • 0027276081 scopus 로고
    • Lipid bilayer partitioning and stability of camptothecin drugs
    • Burke TG, Mishra AK, Wani MC, Wall ME. 1993. Lipid bilayer partitioning and stability of camptothecin drugs. Biochemistry 32:5352-5364.
    • (1993) Biochemistry , vol.32 , pp. 5352-5364
    • Burke, T.G.1    Mishra, A.K.2    Wani, M.C.3    Wall, M.E.4
  • 32
    • 0033549870 scopus 로고    scopus 로고
    • Novel A,B,E-ring-modified camptothecins displaying high lipophilicity and markedly improved human blood stabilities
    • Bom D, Curran DP, Chavan AJ, Kruszewski S, Zimmer SG, Fraley KA, Burke TG. 1999. Novel A,B,E-ring-modified camptothecins displaying high lipophilicity and markedly improved human blood stabilities. J Med Chem 42:3018-3022.
    • (1999) J Med Chem , vol.42 , pp. 3018-3022
    • Bom, D.1    Curran, D.P.2    Chavan, A.J.3    Kruszewski, S.4    Zimmer, S.G.5    Fraley, K.A.6    Burke, T.G.7
  • 34
    • 0034917320 scopus 로고    scopus 로고
    • Therapeutic activity of 7-[(2-trimethylsilyl)ethyl)]-20 (S)-camptothecin against central nervous system tumor-derived xenografts in athymic mice
    • Keir ST, Hausheer F, Lawless AA, Bigner DD, Friedman HS. 2001. Therapeutic activity of 7-[(2-trimethylsilyl)ethyl)]-20 (S)-camptothecin against central nervous system tumor-derived xenografts in athymic mice. Cancer Chemother Pharmacol 48: 83-87.
    • (2001) Cancer Chemother Pharmacol , vol.48 , pp. 83-87
    • Keir, S.T.1    Hausheer, F.2    Lawless, A.A.3    Bigner, D.D.4    Friedman, H.S.5
  • 35
    • 3142729057 scopus 로고    scopus 로고
    • Gimatecan, a novel camptothecin with a promising preclinical profile
    • Pratesi G, Beretta GL, Zunino F. 2004. Gimatecan, a novel camptothecin with a promising preclinical profile. Anticancer Drugs 15:545-552.
    • (2004) Anticancer Drugs , vol.15 , pp. 545-552
    • Pratesi, G.1    Beretta, G.L.2    Zunino, F.3
  • 37
    • 0027428116 scopus 로고
    • Plasma pharmacokinetics of lactone and carboxylate forms of 20(S)-camptothecin in anesthetized rats
    • Scott DO, Bindra DS, Stella VJ. 1993. Plasma pharmacokinetics of lactone and carboxylate forms of 20(S)-camptothecin in anesthetized rats. Pharm Res 10:1451-1457.
    • (1993) Pharm Res , vol.10 , pp. 1451-1457
    • Scott, D.O.1    Bindra, D.S.2    Stella, V.J.3
  • 39
    • 0034234238 scopus 로고    scopus 로고
    • Liposomal encapsulation of topotecan enhances anticancer efficacy in murine and human xenograft models
    • Tardi P, Choice E, Masin D, Redelmeier T, Bally M, Madden TD. 2000. Liposomal encapsulation of topotecan enhances anticancer efficacy in murine and human xenograft models. Cancer Res 60:3389-3393.
    • (2000) Cancer Res , vol.60 , pp. 3389-3393
    • Tardi, P.1    Choice, E.2    Masin, D.3    Redelmeier, T.4    Bally, M.5    Madden, T.D.6
  • 40
    • 0036689443 scopus 로고    scopus 로고
    • Stable supersaturated aqueous solutions of silatecan 7-t-butyldimethylsilyl-10-hydroxycamptothecin via chemical conversion in the presence of a chemically modified beta-cyclodextrin
    • Xiang TX, Anderson BD. 2002. Stable supersaturated aqueous solutions of silatecan 7-t-butyldimethylsilyl-10-hydroxycamptothecin via chemical conversion in the presence of a chemically modified beta-cyclodextrin. Pharm Res 19:1215-1222.
    • (2002) Pharm Res , vol.19 , pp. 1215-1222
    • Xiang, T.X.1    Anderson, B.D.2
  • 41
    • 0346392116 scopus 로고    scopus 로고
    • Development and characterization of a novel liposome-based formulation of SN-38
    • Zhang JA, Xuan T, Parmar M, Ma L, Ugwu S, Ali S, Ahmad I. 2004. Development and characterization of a novel liposome-based formulation of SN-38. Int J Pharm 270:93-107.
    • (2004) Int J Pharm , vol.270 , pp. 93-107
    • Zhang, J.A.1    Xuan, T.2    Parmar, M.3    Ma, L.4    Ugwu, S.5    Ali, S.6    Ahmad, I.7
  • 45
    • 38349180056 scopus 로고    scopus 로고
    • Liposome Transport of Hydrophobic Drugs: Gel Phase Lipid Bilayer Permeability and Partitioning of the Lactone Form of a Hydrophobic Camptothecin, DB-67
    • in press
    • Joguparthi V, Xiang TX, Anderson BD. 2006. Liposome Transport of Hydrophobic Drugs: Gel Phase Lipid Bilayer Permeability and Partitioning of the Lactone Form of a Hydrophobic Camptothecin, DB-67. J Pharm Sci (in press).
    • (2006) J Pharm Sci
    • Joguparthi, V.1    Xiang, T.X.2    Anderson, B.D.3
  • 46
    • 0001740071 scopus 로고
    • Body Fluids and Renal Function: Physiology of body fluids
    • West JB, editor, 12th edition. Baltimore: William & Wilkins Publishing Co. pp
    • Laiken ND, Fanestil DD. 1989. Body Fluids and Renal Function: Physiology of body fluids. In: West JB, editor. Best and Taylor's physiological basis of medical practice, 12th edition. Baltimore: William & Wilkins Publishing Co. pp 406-418.
    • (1989) Best and Taylor's physiological basis of medical practice , pp. 406-418
    • Laiken, N.D.1    Fanestil, D.D.2
  • 47
    • 33947180014 scopus 로고    scopus 로고
    • Independence of substituent contributions to the transport of small molecule permeants in lipid bilayers
    • Mayer PT, Xiang TX, Anderson BD. 2000. Independence of substituent contributions to the transport of small molecule permeants in lipid bilayers. AAPS Pharm Sci 2:E14.
    • (2000) AAPS Pharm Sci , vol.2
    • Mayer, P.T.1    Xiang, T.X.2    Anderson, B.D.3
  • 48
    • 0032168937 scopus 로고    scopus 로고
    • The barrier domain for solute permeation varies with lipid bilayer phase structure
    • Xiang T, Xu Y, Anderson BD. 1998. The barrier domain for solute permeation varies with lipid bilayer phase structure. J Membr Biol 165: 77-90.
    • (1998) J Membr Biol , vol.165 , pp. 77-90
    • Xiang, T.1    Xu, Y.2    Anderson, B.D.3
  • 51
    • 0017750205 scopus 로고
    • Diffusion of carbon dioxide through lipid bilayer membranes: Effects of carbonic anhydrase, bicarbonate, and unstirred layers
    • Gutknecht J, Bisson MA, Tosteson FC. 1977. Diffusion of carbon dioxide through lipid bilayer membranes: effects of carbonic anhydrase, bicarbonate, and unstirred layers. J Gen Physiol 69:779-794.
    • (1977) J Gen Physiol , vol.69 , pp. 779-794
    • Gutknecht, J.1    Bisson, M.A.2    Tosteson, F.C.3
  • 52
    • 33645047575 scopus 로고    scopus 로고
    • Development of a highly active nanoliposomal irinotecan using a novel intraliposomal stabilization strategy
    • Drummond DC, Noble CO, Guo Z, Hong K, Park JW, Kirpotin DB. 2006. Development of a highly active nanoliposomal irinotecan using a novel intraliposomal stabilization strategy. Cancer Res 66: 3271-3277.
    • (2006) Cancer Res , vol.66 , pp. 3271-3277
    • Drummond, D.C.1    Noble, C.O.2    Guo, Z.3    Hong, K.4    Park, J.W.5    Kirpotin, D.B.6
  • 53
    • 0032958540 scopus 로고    scopus 로고
    • Intravenous pretreatment with empty pH gradient liposomes alters the pharmacokinetics and toxicity of doxorubicin through in vivo active drug encapsulation
    • Mayer LD, Reamer J, Bally MB. 1999. Intravenous pretreatment with empty pH gradient liposomes alters the pharmacokinetics and toxicity of doxorubicin through in vivo active drug encapsulation. J Pharm Sci 88:96-102.
    • (1999) J Pharm Sci , vol.88 , pp. 96-102
    • Mayer, L.D.1    Reamer, J.2    Bally, M.B.3
  • 54
    • 0016607769 scopus 로고
    • Simple, rapid method for detecting phase transititons of lipids
    • Erdei L, Csorba I, Thuyen HX. 1975. Simple, rapid method for detecting phase transititons of lipids. Lipids 10:115-117.
    • (1975) Lipids , vol.10 , pp. 115-117
    • Erdei, L.1    Csorba, I.2    Thuyen, H.X.3
  • 55
    • 0028149794 scopus 로고
    • Substituent contributions to the transport of substituted p-toluic acids across lipid bilayer membranes
    • Xiang TX, Anderson BD. 1994. Substituent contributions to the transport of substituted p-toluic acids across lipid bilayer membranes. J Pharm Sci 83:1511-1518.
    • (1994) J Pharm Sci , vol.83 , pp. 1511-1518
    • Xiang, T.X.1    Anderson, B.D.2
  • 56
    • 0031026599 scopus 로고    scopus 로고
    • Permeability of acetic acid across gel and liquid-crystalline lipid bilayers conforms to free-surface-area theory
    • Xiang TX, Anderson BD. 1997. Permeability of acetic acid across gel and liquid-crystalline lipid bilayers conforms to free-surface-area theory. Biophys J 72:223-237.
    • (1997) Biophys J , vol.72 , pp. 223-237
    • Xiang, T.X.1    Anderson, B.D.2
  • 57
    • 0032489637 scopus 로고    scopus 로고
    • Phase structures of binary lipid bilayers as revealed by permeability of small molecules
    • Xiang TX, Anderson BD. 1998. Phase structures of binary lipid bilayers as revealed by permeability of small molecules. Biochim Biophys Acta 1370: 64-76.
    • (1998) Biochim Biophys Acta , vol.1370 , pp. 64-76
    • Xiang, T.X.1    Anderson, B.D.2


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