Encapsulation of doxorubicin into thermosensitive liposomes via complexation with the transition metal manganese

Journal of Controlled Release

Volumn 104, Issue 2, 2005, Pages 271-288

  Chiu, Gigi N C ^a,b   Abraham, Sheela A ^a,b   Ickenstein, Ludger M ^a,b   Ng, Rebecca ^a   Karlsson, Göran ^c   Edwards, Katarina ^c   Wasan, Ellen K ^a   Bally, Marcel B ^a,b  

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Doxorubicin; Drug release; Intraliposomal precipitation; Manganese; Thermosensitive liposomes; Transition metal

Indexed keywords

COMPLEXATION; CONTROLLED DRUG DELIVERY; ENCAPSULATION; LIPIDS; MANGANESE; PH; PHARMACOKINETICS; POLYETHYLENE GLYCOLS; PRECIPITATION (CHEMICAL); TRANSMISSION ELECTRON MICROSCOPY;

ACIDIFICATION; DOXORUBICIN; THERMOSENSITIVE LIPOSOMES;

DRUG PRODUCTS;

1 STEAROYL 2 HYDROXYGLYCERO 3 PHOSPHOCHOLINE; 1,2 DISTEAROYLGLYCERO 3 PHOSPHOETHANOLAMINE N [METHOXY(POLYETHYLENE GLYCOL) 2000]; CALCIMYCIN; DIPALMITOYLPHOSPHAATIDYLCHOLINE; DOXORUBICIN; LIPOSOME; MANGANESE; METAL COMPLEX; PHOSPHORYLCHOLINE; TRANSITION ELEMENT; UNCLASSIFIED DRUG;

ACIDIFICATION; ARTICLE; COMPARATIVE STUDY; COMPLEX FORMATION; DRUG FORMULATION; DRUG RELEASE; ENCAPSULATION; HEAT SENSITIVITY; MORPHOLOGY; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY; TRANSMISSION ELECTRON MICROSCOPY;

CALCIMYCIN; CRYOELECTRON MICROSCOPY; DOXORUBICIN; DRUG CARRIERS; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MANGANESE;

EID: 19444362531     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.02.009     Document Type: Article

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