SCOPUS 정보 검색 플랫폼

Volumn 19, Issue 8, 2002, Pages 1215-1222

Stable supersaturated aqueous solutions of silatecan 7-t-butyldimethylsilyl-10-hydroxycamptothecin via chemical conversion in the presence of a chemically modified β-cyclodextrin

(2) Xiang, Tian Xiang a Anderson, Bradley D a

a University of Kentucky (United States)

Author keywords

Camptothecin analogs; Cyclodextrin complexes; Lactone hydrolysis; Parenteral formulation; Solubilization

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ANTINEOPLASTIC AGENT; BETA CYCLODEXTRIN; BETA CYCLODEXTRIN SULFOBUTYL ETHER; CAMPTOTHECIN DERIVATIVE; CARBOXYLIC ACID; DB 67; DIMETHYL SULFOXIDE; FUNCTIONAL GROUP; LACTONE; SILATECAN 7 TERT BUTYLDIMETHYLSILYL 10 HYDROXYCAMPTOTHECIN; SOLVENT; UNCLASSIFIED DRUG; WATER;

ACIDIFICATION; ALKALINITY; AQUEOUS SOLUTION; ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; CHEMICAL REACTION KINETICS; CIRCULAR DICHROISM; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; FREEZE DRYING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INJECTION; LIPOPHILICITY; METHODOLOGY; PH; PRECIPITATION; PRIORITY JOURNAL; STOICHIOMETRY; ULTRAVIOLET RADIATION;

BETA-CYCLODEXTRINS; CAMPTOTHECIN; CYCLODEXTRINS; DRUG STABILITY; ORGANOSILICON COMPOUNDS; PHARMACEUTICAL SOLUTIONS;

EID: 0036689443 PISSN: 07248741 EISSN: None Source Type: Journal
DOI: 10.1023/A:1019862629357 Document Type: Article

Times cited : (37)

References (17)

1
- 0029846340
- Solubility principles and practices for parenteral drug dosage form development
- (1996) PDA J. Pharm. Sci. Technol. , vol.50 , pp. 330-342
- Sweetana, S.¹ Akers, M.J.²

2
- 0003882857
- John Wiley & Sons, Inc., New York
- (1990) Solubility Behavior of Organic Compounds
- Grant, D.J.W.¹ Higuchi, T.²

3
- 0025907884
- Oversaturated solutions of drug in hydroxypropylcyclodextrins: Parenteral preparation of pancratistatin
- (1990) J. Pharm. Sci. , vol.80 , pp. 384-386
- Torres-Labandeira, J.J.¹ Davignon, P.² Pitha, J.³

4
- 0034687233
- The novel silatecan 7-tert-butyldimethylsilyl-10-hydroxycamptothecin displays high lipophilicity, improved human blood stability, and potent anticancer activity
- (2000) J. Med. Chem. , vol.43 , pp. 3970-3980
- Bom, D.¹ Curran, D.P.² Kruszewski, S.³ Zimmer, S.G.⁴ Thompson, S.J.⁵ Kohlhagen, G.⁶ Du, W.⁷ Chavan, A.J.⁸ Fraley, K.A.⁹ Bingcang, A.L.¹⁰ Latus, J.J.¹¹ Pommier, Y.¹² Burke, T.G.¹³

5
- 0024560495
- Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: Evidence for a specific receptor site and a relation to antitumor activity
- (1989) Cancer Res. , vol.49 , pp. 1465-1469
- Jaxel, C.¹ Kohn, K.W.² Wani, M.C.³ Wall, M.E.⁴ Pommier, Y.⁵

6
- 0024420685
- Arrest of replication forks by drug-stabilized topoisopomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
- (1989) Cancer Res. , vol.49 , pp. 5077-5082
- Hsiang, Y.H.¹ Lihou, M.G.² Liu, L.F.³

7
- 0024356003
- DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogues
- (1989) Cancer Res. , vol.49 , pp. 4385-4389
- Hsiang, Y.H.¹ Liu, L.F.² Wall, M.E.³ Wani, M.C.⁴ Nicholas, A.W.⁵ Manikumar, G.⁶ Kirschenbaum, S.⁷ Silber, R.⁸ Potmesil, M.⁹

8
- 0024537205
- Modification of the hydroxy lactone ring of camptothecin: Inhibition of mammalian topoisomerase I and biologic activity
- (1989) J. Med. Chem. , vol.32 , pp. 715-720
- Hertzberg, R.P.¹ Caranfa, M.J.² Holden, K.G.³ Jakas, D.R.⁴ Gallagher, G.⁵ Mattern, M.R.⁶ Mong, S.M.⁷ Bartus, J.O.⁸ Johnson, R.K.⁹ Kingsbury, W.D.¹⁰

9
- 0029003314
- Altered topoisomerase I expression in two subclones of human CEM leukemia selected for resistance to camptothecin
- (1995) Oncol. Res. , vol.7 , pp. 83-95
- Kapoor, R.¹ Slade, D.L.² Fujimori, A.³ Pommier, Y.⁴ Harker, W.G.⁵

10
- 0031796343
- Irinotecan in lymphoma, leukemia, and breast, pancreatic, ovarian, and small-cell lung cancers
- (1998) Oncology (Huntingt) , vol.12 , pp. 103-109
- Rosen, L.S.¹

11
- 0032922740
- Topotecan - A novel topoisomerase I inhibitor: Pharmacology and clinical experience
- (1999) Oncology , vol.56 , pp. 1-12
- Kollmannsberger, C.¹ Mross, K.² Jakob, A.³ Kanz, L.⁴ Bokemeyer, C.⁵

12
- 0033774616
- Camptothecin analogues with enhanced antitumor activity at acidic pH
- (2000) Cancer Chemother. Pharmacol. , vol.46 , pp. 263-271
- Adams, D.J.¹ Dewhirst, M.W.² Flowers, J.L.³ Gamcsik, M.P.⁴ Colvin, O.M.⁵ Manikumar, G.⁶ Wani, M.C.⁷ Wall, M.E.⁸

13
- 0034866490
- Recent advances in the chemotherapy of non-small cell lung cancer
- (2001) Jpn. J. Clin. Oncol. , vol.31 , pp. 299-304
- Inoue, A.¹ Saijo, N.²

14
- 0027096415
- A kinetic mechanistic study of the hydrolysis of camptothecin some analogues
- (1992) J. Pharm. Sci. , vol.81 , pp. 676-684
- Fassberg, J.¹ Stella, V.J.²

15
- 0027220642
- Pharmacokinetics of the 9-amino and 10,11-methylenedioxy derivatives of camptothecin in mice
- (1993) Cancer Res. , vol.53 , pp. 3062-3069
- Supko, J.G.¹ Malspeis, L.²

16
- 0010267346
- Phase I/pharmacokinetic study of topotecan by 24-hour continuous infusion weekly
- (1994) Cancer Res. , vol.54 , pp. 1220-1226
- Haas, N.B.¹ LaCreta, F.P.² Walczak, J.³ Hudes, G.R.⁴ Brennan, J.M.⁵ Ozols, R.F.⁶ O'Dwyer, P.J.⁷

17
- 33746190548
- A spectrophotometric investigation of the interaction of iodine with aromatic hydrocarbons
- (1949) J. Am. Chem. Soc. , vol.71 , pp. 2703-2707
- Benesi, H.A.¹ Hildebrand, J.H.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.