A versatile prodrug approach for liposomal core-loading of water-insoluble camptothecin anticancer drugs

Journal of the American Chemical Society

Volumn 124, Issue 26, 2002, Pages 7650-7651

  Liu, Xinli ^a,b,c   Lynn, Bert C ^a,b,c   Zhang, Junhong ^a,b,c   Song, Lin ^a,b,c   Bom, David ^a,b,c   Du, Wu ^a,b,c   Curran, Dennis P ^a,b,c   Burke, Thomas G ^a,b,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b Tigen Pharmaceuticals Inc   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; 7 TERT BUTYLDIMETHYLSILYL 10 HYDROXYCAMPTOTHECIN; ANTINEOPLASTIC AGENT; CAMPTOTHECIN DERIVATIVE; CDK 602; DB 67; IRINOTECAN; LIPOSOME; LURTOTECAN; PRODRUG; TOPOTECAN; UNCLASSIFIED DRUG;

ARTICLE; DRUG DETERMINATION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG SYNTHESIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; DRUG CARRIERS; LIPOSOMES; PRODRUGS; SOLUBILITY; WATER;

EID: 0037014697     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0256212     Document Type: Article

References (22)

1. The camptothecins: Unfolding their anticancer potential