-
1
-
-
11144236161
-
A walk-through of the yeast mating pheromone response pathway
-
Bardwell L (2005) A walk-through of the yeast mating pheromone response pathway. Peptides 26 : 339 350.
-
(2005)
Peptides
, vol.26
, pp. 339-350
-
-
Bardwell, L.1
-
2
-
-
0030987069
-
How receptors talk to trimeric G proteins
-
Bourne HR (1997) How receptors talk to trimeric G proteins. Curr Opin Cell Biol 9 : 134 142.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 134-142
-
-
Bourne, H.R.1
-
3
-
-
0035942238
-
Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: Use of a photoactivatable reagent
-
Cai K, Itoh Y Khorana HG (2001) Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent. Proc Natl Acad Sci USA 98 : 4877 4882.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4877-4882
-
-
Cai, K.1
Itoh, Y.2
Khorana, H.G.3
-
4
-
-
0025605219
-
Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2
-
Chang F Herskowitz I (1990) Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2. Cell 63 : 999 1011.
-
(1990)
Cell
, vol.63
, pp. 999-1011
-
-
Chang, F.1
Herskowitz, I.2
-
5
-
-
0037221946
-
Activation of G-protein Galpha subunits by receptors through Gα-Gβ and Gα-Gγ interactions
-
Cherfils J Chabre M (2003) Activation of G-protein Galpha subunits by receptors through Gα-Gβ and Gα-Gγ interactions. Trends Biochem Sci 28 : 13 17.
-
(2003)
Trends Biochem Sci
, vol.28
, pp. 13-17
-
-
Cherfils, J.1
Chabre, M.2
-
6
-
-
1942501726
-
Subunits of a yeast oligomeric G protein-coupled receptor are activated independently by agonist but function in concert to activate G protein heterotrimers
-
Chinault SL, Overton MC Blumer KJ (2004) Subunits of a yeast oligomeric G protein-coupled receptor are activated independently by agonist but function in concert to activate G protein heterotrimers. J Biol Chem 279 : 16091 16100.
-
(2004)
J Biol Chem
, vol.279
, pp. 16091-16100
-
-
Chinault, S.L.1
Overton, M.C.2
Blumer, K.J.3
-
7
-
-
33845959757
-
Accessibility of Cys residues substituted into the cytoplasmic regions of the α-factor receptor identifies the intracellular residues that are available for G protein interaction
-
Choi Y Konopka JB (2006) Accessibility of Cys residues substituted into the cytoplasmic regions of the α-factor receptor identifies the intracellular residues that are available for G protein interaction. Biochemistry 15310 15317.
-
(2006)
Biochemistry
, pp. 15310-15317
-
-
Choi, Y.1
Konopka, J.B.2
-
8
-
-
0028286250
-
Systematic mutagenesis of the yeast mating pheromone receptor third intracellular loop
-
Clark CD, Palzkill T Botstein D (1994) Systematic mutagenesis of the yeast mating pheromone receptor third intracellular loop. J Biol Chem 269 : 8831 8841.
-
(1994)
J Biol Chem
, vol.269
, pp. 8831-8841
-
-
Clark, C.D.1
Palzkill, T.2
Botstein, D.3
-
9
-
-
0034923514
-
Regulation of G protein-initiated signal transduction in yeast: Paradigms and principles
-
Dohlman HG Thorner JW (2001) Regulation of G protein-initiated signal transduction in yeast: paradigms and principles. Annu Rev Biochem 70 : 703 754.
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 703-754
-
-
Dohlman, H.G.1
Thorner, J.W.2
-
10
-
-
0029767982
-
Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: Expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit)
-
Dohlman HG, Song J, Ma D, Courchesne WE Thorner J (1996) Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit). Mol Cell Biol 16 : 5194 5209.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5194-5209
-
-
Dohlman, H.G.1
Song, J.2
Ma, D.3
Courchesne, W.E.4
Thorner, J.5
-
11
-
-
0034714383
-
Interaction between transmembrane domains 5 and 6 in the α-factor receptor
-
Dube P, DeConstanzo A Konopka JB (2000) Interaction between transmembrane domains 5 and 6 in the α-factor receptor. J Biol Chem 275 : 26492 26499.
-
(2000)
J Biol Chem
, vol.275
, pp. 26492-26499
-
-
Dube, P.1
Deconstanzo, A.2
Konopka, J.B.3
-
12
-
-
3242773021
-
A concept for G protein activation by G protein-coupled receptor dimers: The transducin/rhodopsin interface
-
Filipek S, Krzysko KA, Fotiadis D, Liang Y, Saperstein DA, Engel A Palczewski K (2004) A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface. Photochem Photobiol Sci 3 : 628 638.
-
(2004)
Photochem Photobiol Sci
, vol.3
, pp. 628-638
-
-
Filipek, S.1
Krzysko, K.A.2
Fotiadis, D.3
Liang, Y.4
Saperstein, D.A.5
Engel, A.6
Palczewski, K.7
-
13
-
-
0031717187
-
Cys-scanning mutagenesis: A novel approach to structure function relationships in polytopic membrane proteins
-
Frillingos S, Sahin-Toth M, Wu J Kaback HR (1998) Cys-scanning mutagenesis: a novel approach to structure function relationships in polytopic membrane proteins. FASEB J 12 : 1281 1299.
-
(1998)
FASEB J
, vol.12
, pp. 1281-1299
-
-
Frillingos, S.1
Sahin-Toth, M.2
Wu, J.3
Kaback, H.R.4
-
14
-
-
0024266139
-
New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
-
Gietz RD Sugino A (1988) New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74 : 527 534.
-
(1988)
Gene
, vol.74
, pp. 527-534
-
-
Gietz, R.D.1
Sugino, A.2
-
15
-
-
0031473847
-
SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
-
Guex N Peitsch MC (1997) SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 18 : 2714 2723.
-
(1997)
Electrophoresis
, vol.18
, pp. 2714-2723
-
-
Guex, N.1
Peitsch, M.C.2
-
16
-
-
0035942220
-
How activated receptors couple to G proteins
-
Hamm HE (2001) How activated receptors couple to G proteins. Proc Natl Acad Sci USA 98 : 4819 4821.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4819-4821
-
-
Hamm, H.E.1
-
17
-
-
0026083213
-
The carboxyl-terminus of Scg1, the Gα subunit involved in yeast mating, is implicated in interactions with the pheromone receptors
-
Hirsch JP, Dietzel C Kurjan J (1991) The carboxyl-terminus of Scg1, the Gα subunit involved in yeast mating, is implicated in interactions with the pheromone receptors. Genes Dev 5 : 467 474.
-
(1991)
Genes Dev
, vol.5
, pp. 467-474
-
-
Hirsch, J.P.1
Dietzel, C.2
Kurjan, J.3
-
18
-
-
0035942229
-
Mapping of contact sites in complex formation between light-activated rhodopsin and transducin by covalent crosslinking: Use of a chemically preactivated reagent
-
Itoh Y, Cai K Khorana HG (2001) Mapping of contact sites in complex formation between light-activated rhodopsin and transducin by covalent crosslinking: use of a chemically preactivated reagent. Proc Natl Acad Sci USA 98 : 4883 4887.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4883-4887
-
-
Itoh, Y.1
Cai, K.2
Khorana, H.G.3
-
19
-
-
0031002349
-
Analysis of the receptor binding domain of Gpa1p, the Gα subunit involved in the yeast pheromone response pathway
-
Kallal L Kurjan J (1997) Analysis of the receptor binding domain of Gpa1p, the Gα subunit involved in the yeast pheromone response pathway. Mol Cell Biol 17 : 2897 2907.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 2897-2907
-
-
Kallal, L.1
Kurjan, J.2
-
20
-
-
0036385914
-
Structure and orientation of a G protein fragment in the receptor bound state from residual dipolar couplings
-
Koenig BW, Kontaxis G, Mitchell DC, Louis JM, Litman BJ Bax A (2002) Structure and orientation of a G protein fragment in the receptor bound state from residual dipolar couplings. J Mol Biol 322 : 441 461.
-
(2002)
J Mol Biol
, vol.322
, pp. 441-461
-
-
Koenig, B.W.1
Kontaxis, G.2
Mitchell, D.C.3
Louis, J.M.4
Litman, B.J.5
Bax, A.6
-
21
-
-
0028338534
-
GCRDb: A G-protein-coupled receptor database
-
Kolakowski LF Jr. (1994) GCRDb: a G-protein-coupled receptor database. Receptors Channels 2 : 1 7.
-
(1994)
Receptors Channels
, vol.2
, pp. 1-7
-
-
Kolakowski Jr., L.F.1
-
22
-
-
0029664589
-
The 2.0 a crystal structure of a heterotrimeric G protein
-
Lambright DG, Sondek J, Bohm A, Skiba NP, Hamm HE Sigler PB (1996) The 2.0 A crystal structure of a heterotrimeric G protein. Nature 379 : 311 319.
-
(1996)
Nature
, vol.379
, pp. 311-319
-
-
Lambright, D.G.1
Sondek, J.2
Bohm, A.3
Skiba, N.P.4
Hamm, H.E.5
Sigler, P.B.6
-
23
-
-
33644994483
-
Dual role for membrane localization in yeast MAP kinase cascade activation and its contribution to signaling fidelity
-
Lamson RE, Takahashi S, Winters MJ Pryciak PM (2006) Dual role for membrane localization in yeast MAP kinase cascade activation and its contribution to signaling fidelity. Curr Biol 16 : 618 623.
-
(2006)
Curr Biol
, vol.16
, pp. 618-623
-
-
Lamson, R.E.1
Takahashi, S.2
Winters, M.J.3
Pryciak, P.M.4
-
24
-
-
6344248639
-
Structure of bovine rhodopsin in a trigonal crystal form
-
Li J, Edwards PC, Burghammer M, Villa C Schertler GF (2004) Structure of bovine rhodopsin in a trigonal crystal form. J Mol Biol 343 : 1409 1438.
-
(2004)
J Mol Biol
, vol.343
, pp. 1409-1438
-
-
Li, J.1
Edwards, P.C.2
Burghammer, M.3
Villa, C.4
Schertler, G.F.5
-
25
-
-
0032496281
-
Identification of amino acid residues of Gsα critical to repression of adipogenesis
-
Liu X, Malbon CC Wang HY (1998) Identification of amino acid residues of Gsα critical to repression of adipogenesis. J Biol Chem 273 : 11685 11694.
-
(1998)
J Biol Chem
, vol.273
, pp. 11685-11694
-
-
Liu, X.1
Malbon, C.C.2
Wang, H.Y.3
-
26
-
-
0035498937
-
Receptor activation: What does the rhodopsin structure tell us?
-
Meng EC Bourne HR (2001) Receptor activation: what does the rhodopsin structure tell us? Trends Pharmacol Sci 22 : 587 593.
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 587-593
-
-
Meng, E.C.1
Bourne, H.R.2
-
27
-
-
0035719181
-
Functional assays for mammalian G-protein-coupled receptors in yeast
-
Mentesana PE, Dosil M Konopka JB (2002) Functional assays for mammalian G-protein-coupled receptors in yeast. Methods Enzymol 344 : 92 111.
-
(2002)
Methods Enzymol
, vol.344
, pp. 92-111
-
-
Mentesana, P.E.1
Dosil, M.2
Konopka, J.B.3
-
28
-
-
0003785155
-
-
pp. Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
-
Miller JH (1972) Experiments in Molecular Genetics, pp. 325 355. Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
-
(1972)
Experiments in Molecular Genetics
, pp. 325-355
-
-
Miller, J.H.1
-
29
-
-
1942435227
-
Sexual conjugation in yeast: A paradigm to study G-protein-coupled receptor domain structure
-
Naider F, Estephan R, Englander J, Suresh Babu VV, Arevalo E, Samples K Becker JM (2004) Sexual conjugation in yeast: a paradigm to study G-protein-coupled receptor domain structure. Biopolymers 76 : 119 128.
-
(2004)
Biopolymers
, vol.76
, pp. 119-128
-
-
Naider, F.1
Estephan, R.2
Englander, J.3
Suresh Babu, V.V.4
Arevalo, E.5
Samples, K.6
Becker, J.M.7
-
30
-
-
0000923617
-
Common signal transduction system shared by STE2 and STE3 in haploid cells of Saccharomyces cerevisiae: Autocrine cell-cycle arrest results from forced expression of STE2
-
Nakayama N, Miyajima A Arai K (1987) Common signal transduction system shared by STE2 and STE3 in haploid cells of Saccharomyces cerevisiae: autocrine cell-cycle arrest results from forced expression of STE2. EMBO J 6 : 249 254.
-
(1987)
EMBO J
, vol.6
, pp. 249-254
-
-
Nakayama, N.1
Miyajima, A.2
Arai, K.3
-
31
-
-
4344581120
-
The retinal conformation and its environment in rhodopsin in light of a new 2.2 a crystal structure
-
Okada T, Sugihara M, Bondar AN, Elstner M, Entel P Buss V (2004) The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure. J Mol Biol 342 : 571 583.
-
(2004)
J Mol Biol
, vol.342
, pp. 571-583
-
-
Okada, T.1
Sugihara, M.2
Bondar, A.N.3
Elstner, M.4
Entel, P.5
Buss, V.6
-
32
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski K, Kumasaka T, Hori T et al 2000) Crystal structure of rhodopsin: a G protein-coupled receptor. Science 289 : 739 745.
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Al, E.4
-
33
-
-
0034603061
-
Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles
-
Roberts CJ, Nelson B, Marton MJ et al 2000) Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles. Science 287 : 873 880.
-
(2000)
Science
, vol.287
, pp. 873-880
-
-
Roberts, C.J.1
Nelson, B.2
Marton, M.J.3
Al, E.4
-
34
-
-
2942623922
-
Translating G protein subunit diversity into functional specificity
-
Robishaw JD Berlot CH (2004) Translating G protein subunit diversity into functional specificity. Curr Opin Cell Biol 16 : 206 209.
-
(2004)
Curr Opin Cell Biol
, vol.16
, pp. 206-209
-
-
Robishaw, J.D.1
Berlot, C.H.2
-
35
-
-
1842737267
-
Effects of mutations in the N terminal region of the yeast G protein alpha-subunit Gpa1p on signaling by pheromone receptors
-
Roginskaya M, Connelly SM, Kim KS, Patel D Dumont ME (2004) Effects of mutations in the N terminal region of the yeast G protein alpha-subunit Gpa1p on signaling by pheromone receptors. Mol Genet Genomics 271 : 237 248.
-
(2004)
Mol Genet Genomics
, vol.271
, pp. 237-248
-
-
Roginskaya, M.1
Connelly, S.M.2
Kim, K.S.3
Patel, D.4
Dumont, M.E.5
-
36
-
-
0035933167
-
Mutant G protein alpha subunit activated by Gbeta gamma: A model for receptor activation?
-
Rondard P, Iiri T, Srinivasan S, Meng E, Fujita T Bourne HR (2001) Mutant G protein alpha subunit activated by Gbeta gamma: a model for receptor activation? Proc Natl Acad Sci USA 98 : 6150 6155.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6150-6155
-
-
Rondard, P.1
Iiri, T.2
Srinivasan, S.3
Meng, E.4
Fujita, T.5
Bourne, H.R.6
-
37
-
-
0036275447
-
Getting started with yeast
-
Sherman F (2002) Getting started with yeast. Methods Enzymol 350 : 3 41.
-
(2002)
Methods Enzymol
, vol.350
, pp. 3-41
-
-
Sherman, F.1
-
38
-
-
0348010316
-
Closely related G-protein-coupled receptors use multiple and distinct domains on G-protein alpha-subunits for selective coupling
-
Slessareva JE, Ma H, Depree KM, Flood LA, Bae H, Cabrera-Vera TM, Hamm HE Graber SG (2003) Closely related G-protein-coupled receptors use multiple and distinct domains on G-protein alpha-subunits for selective coupling. J Biol Chem 278 : 50530 50536.
-
(2003)
J Biol Chem
, vol.278
, pp. 50530-50536
-
-
Slessareva, J.E.1
Ma, H.2
Depree, K.M.3
Flood, L.A.4
Bae, H.5
Cabrera-Vera, T.M.6
Hamm, H.E.7
Graber, S.G.8
-
39
-
-
33745685061
-
Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome
-
Slessareva JE, Routt SM, Temple B, Bankaitis VA Dohlman HG (2006) Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. Cell 126 : 191 203.
-
(2006)
Cell
, vol.126
, pp. 191-203
-
-
Slessareva, J.E.1
Routt, S.M.2
Temple, B.3
Bankaitis, V.A.4
Dohlman, H.G.5
-
40
-
-
0029786317
-
Regulation of membrane and subunit interactions by N-myristoylation of a G protein α subunit in yeast
-
Song J, Hirschman J, Gunn K Dohlman HG (1996) Regulation of membrane and subunit interactions by N-myristoylation of a G protein α subunit in yeast. J Biol Chem 271 : 20273 20283.
-
(1996)
J Biol Chem
, vol.271
, pp. 20273-20283
-
-
Song, J.1
Hirschman, J.2
Gunn, K.3
Dohlman, H.G.4
-
41
-
-
1542358991
-
Inherited diseases involving G proteins and G protein-coupled receptors
-
Spiegel AM Weinstein LS (2004) Inherited diseases involving G proteins and G protein-coupled receptors. Annu Rev Med 55 : 27 39.
-
(2004)
Annu Rev Med
, vol.55
, pp. 27-39
-
-
Spiegel, A.M.1
Weinstein, L.S.2
-
42
-
-
0030920782
-
G protein mechanisms: Insights from structural analysis
-
Sprang SR (1997) G protein mechanisms: insights from structural analysis. Annu Rev Biochem 66 : 639 678.
-
(1997)
Annu Rev Biochem
, vol.66
, pp. 639-678
-
-
Sprang, S.R.1
-
43
-
-
0023376280
-
Two genes required for cell fusion during yeast conjugation: Evidence for a pheromone-induced surface protein
-
Trueheart J, Boeke JD Fink GR (1987) Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein. Mol Cell Biol 7 : 2316 2328.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 2316-2328
-
-
Trueheart, J.1
Boeke, J.D.2
Fink, G.R.3
-
44
-
-
0029593456
-
The structure of the G protein heterotrimer Giα1β1γ2
-
Wall MA, Coleman DE, Lee E, Iniguez-Lluhi JA, Posner BA, Gilman AG Sprang SR (1995) The structure of the G protein heterotrimer Giα1β1γ 2. Cell 83 : 1047 1058.
-
(1995)
Cell
, vol.83
, pp. 1047-1058
-
-
Wall, M.A.1
Coleman, D.E.2
Lee, E.3
Iniguez-Lluhi, J.A.4
Posner, B.A.5
Gilman, A.G.6
Sprang, S.R.7
-
45
-
-
0028289437
-
Genetic identification of residues involved in association of alpha and beta G-protein subunits
-
Whiteway M, Clark KL, Leberer E, Dignard D Thomas DY (1994) Genetic identification of residues involved in association of alpha and beta G-protein subunits. Mol Cell Biol 14 : 3223 3229.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3223-3229
-
-
Whiteway, M.1
Clark, K.L.2
Leberer, E.3
Dignard, D.4
Thomas, D.Y.5
-
46
-
-
34250666273
-
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
-
Whorton MR, Bokoch MP, Rasmussen SG, Huang B, Zare RN, Kobilka B Sunahara RK (2007) A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc Natl Acad Sci USA 104 : 7682 7687.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7682-7687
-
-
Whorton, M.R.1
Bokoch, M.P.2
Rasmussen, S.G.3
Huang, B.4
Zare, R.N.5
Kobilka, B.6
Sunahara, R.K.7
-
47
-
-
4143113455
-
Dominant-negative inhibition of pheromone receptor signaling by a single point mutation in the G protein alpha subunit
-
Wu YL, Hooks SB, Harden TK Dohlman HG (2004) Dominant-negative inhibition of pheromone receptor signaling by a single point mutation in the G protein alpha subunit. J Biol Chem 279 : 35287 35297.
-
(2004)
J Biol Chem
, vol.279
, pp. 35287-35297
-
-
Wu, Y.L.1
Hooks, S.B.2
Harden, T.K.3
Dohlman, H.G.4
|