Dominant-negative inhibition of pheromone receptor signaling by a single point mutation in the G protein α subunit

Journal of Biological Chemistry

Volumn 279, Issue 34, 2004, Pages 35287-35297

  Wu, Yuh Lin ^a   Hooks, Shelley B ^a   Harden, T Kendall ^a   Dohlman, Henrik G ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISSOCIATION; ENZYME INHIBITION; HYDROLYSIS; YEAST;

PHEROMONE RECEPTOR SIGNALING; SINGLE POINT MUTATION;

PROTEINS;

GPA1 PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN SUBUNIT; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; MUTANT PROTEIN; PHEROMONE RECEPTOR; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

AGONIST; ARTICLE; DOMINANT NEGATIVE MUTANT; ENZYME ACTIVITY; HORMONE RESPONSE; IN VITRO STUDY; MUTANT; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR BINDING; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

ESCHERICHIA COLI; GTP-BINDING PROTEIN ALPHA SUBUNITS; POINT MUTATION; RECEPTORS, PHEROMONE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION;

PROKARYOTA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 4143113455     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M404896200     Document Type: Article

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