Mutant G protein α subunit activated by Gβγ: A model for receptor activation?

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 11, 2001, Pages 6150-6155

  Rondard, Philippe ^a   Iiri, Taroh ^b   Srinivasan, Supriya ^a   Meng, Elaine ^a   Fujita, Toshiro ^b   Bourne, Henry R ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; ENZYME REGULATION; GENE MUTATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; GUANOSINE DIPHOSPHATE; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS;

ANIMALIA;

EID: 0035933167     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.101136198     Document Type: Article

References (45)

1. Hamm, H. E. (1998) J. Biol. Chem. 273, 669-672.
2. Ferguson, K. M., Higashijima, T., Smigel, M. D. & Gilman, A. G. (1986) J. Biol. Chem. 261, 7393-7399.
3. Lambright, D. G., Sondek, J., Bohm, A., Skiba, N. P., Hamm, H. E. & Sigler, P. B. (1996) Nature (London) 379, 311-319.
4. Wall, M. A., Coleman, D. E., Lee, E., Iñiguez-Lluhi, J. A., Posner, B. A., Gilman, A. G. & Sprang, S. R. (1995) Cell 83, 1047-1058.
5. Bourne, H. R. (1997) Curr. Opin. Cell Biol. 9, 134-142.
6. Onrust, R., Herzmark, P., Chi, P., Garcia, P. D., Lichtarge, O., Kingsley, C. & Bourne, H. R. (1997) Science 275, 381-384.
7. Bohm, A., Gaudet, R. & Sigler, P. B. (1997) Curr. Opin. Biotechnol. 8, 480-487.
8. Iiri, T., Farfel, Z. & Bourne, H. R. (1998) Nature (London) 394, 35-38.
9. Fung, B. K. (1983) J. Biol. Chem. 258, 10495-10502.
10. Kisselev, O. G., Kao, J., Ponder, J. W., Fann, Y. C., Gautam, N. & Marshall, G. R. (1998) Proc. Natl. Acad. Sci. USA 95, 4270-4275.
11. Kisselev, O. G., Meyer, C. K., Heck, M., Ernst, O. P. & Hofmann, K. P. (1999) Proc. Natl. Acad. Sci. USA 96, 4898-4903.
12. Ford, C. E., Skiba, N. P., Bae, H., Daaka, Y., Reuveny, E., Shekter, L. R., Rosal, R., Weng, G., Yang, C. S., Iyengar, R., et al. (1998) Science 280, 1271-1274.
13. Kawashima, T., Berthet-Colominas, C., Wulff, M., Cusack, S. & Leberman, R. (1996) Nature (London) 381, 511-518.
14. Wang, Y., Jiang, Y., Meyering-Voss, M., Sprinzl, M. & Sigler, P. B. (1997) Nat. Struct. Biol. 4, 650-656.
15. Boriack-Sjodin, P. A., Margarit, S. M., Bar-Sagi, D. & Kuriyan, J. (1998) Nature (London) 394, 337-343.
16. Goldberg, J. (1998) Cell 95, 237-248.
17. Worthylake, D. K., Rossman, K. L. & Sondek, J. (2000) Nature (London) 408, 682-688.
18. Levis, M. J. & Bourne, H. R. (1992) J. Cell Biol. 119, 1297-1307.
19. Fishburn, C. S., Pollitt, S. K. & Bourne, H. R. (2000) Proc. Natl. Acad. Sci. USA 97, 1085-1090.
20. Garcia, P. D., Onrust, R., Bell, S. M., Sakmar, T. P. & Bourne, H. R. (1995) EMBO J. 14, 4460-4469.
21. Berlot, C. H. & Bourne, H. R. (1992) Cell 68, 911-922.
22. Morales, J., Fishburn, C. S., Wilson, P. T. & Bourne, H. R. (1998) Mol. Biol. Cell 9, 1-14.
23. Iiri, T., Bell, S. M., Baranski, T. J., Fujita, T. & Bourne, H. R. (1999) Proc. Natl. Acad. Sci. USA 96, 499-504.
24. Wong, H. Y. (1994) Methods Enzymol. 238, 81-94.
25. Graziano, M. P., Freissmuth, M. & Gilman, A. G. (1989) J. Biol. Chem. 264, 409-418.
26. Sprang, S. R. (1997) Annu. Rev. Biochem. 66, 639-678.
27. Wedegaertner, P. B., Chu, D. H., Wilson, P. T., Levis, M. J. & Bourne, H. R. (1993) J. Biol. Chem. 268, 25001-25008.
28. Wedegaertner, P. B. & Bourne, H. R. (1994) Cell 77, 1063-1070.
29. Iiri, T., Backlund, P. S., Jones, T. L. Z., Wedegaertner, P. B. & Bourne, H. R. (1996) Proc. Natl. Acad. Sci. USA 93, 14592-14597.
30. Degtyarev, M. Y., Spiegel, A. M. & Jones, T. L. (1994) J. Biol. Chem. 269, 30898-30903.
31. Evanko, D. S., Thiyagarajan, M. M. & Wedegaertner, P. B. (2000) J. Biol. Chem. 275, 1327-1336.
32. Masters, S. B., Miller, R. T., Chi, M. H., Chang, F. H., Beiderman, B., Lopez, N. G. & Bourne, H. R. (1989) J. Biol. Chem. 264, 15467-15474.
33. Landis, C. A., Masters, S. B., Spada, A., Pace, A. M., Bourne, H. R. & Vallar, L. (1989) Nature (London) 340, 692-696.
34. Graziano, M. P. & Gilman, A. G. (1989) J. Biol. Chem. 264, 15475-15482.
35. Iiri, T., Herzmark, P., Nakamoto, J. M., van Dop, C. & Bourne, H. R. (1994) Nature (London) 371, 164-168.
36. Higashijima, T., Ferguson, K. M., Sternweis, P. C., Smigel, M. D. & Gilman, A. G. (1987) J. Biol. Chem. 262, 762-766.
37. Sondek, J., Bohm, A., Lambright, D. G., Hamm, H. E. & Sigler, P. B. (1996) Nature (London) 379, 369-374.
38. Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Le Trong, I., Teller, D. C., Okada, T., Stenkamp, R. E., et al. (2000) Science 289, 739-745.
39. Bourne, H. R. & Meng, E. C. (2000) Science 289, 733-734.
40. Jones, K. A., Borowsky, B., Tamm, J. A., Craig, D. A., Durkin, M. M., Dai, M., Yao, W. J., Johnson, M., Gunwaldsen, C., Huang, L. Y., et al. (1998) Nature (London) 396, 674-679.
41. Kaupmann, K., Malitschek, B., Schuler, V., Heid, J., Froestl, W., Beck, P., Mosbacher, J., Bischoff, S., Kulik, A., Shigemoto, R., et al. (1998) Nature (London) 396, 683-687.
42. White, J. H., Wise, A., Main, M. J., Green, A., Fraser, N. J., Disney, G. H., Barnes, A. A., Emson, P., Foord, S. M. & Marshall, F. H. (1998) Nature (London) 396, 679-682.
43. Jordan, B. A. & Devi, L. A. (1999) Nature (London) 399, 697-700.
44. Ginés, S., Hillion, J., Torvinen, M., Le Crom, S., Casadó, V., Canela, E. I., Rondin, S., Lew, J. Y., Watson, S., Zoli, M., et al. (2000) Proc. Natl. Acad. Sci. USA 97, 8606-8611.
45. Rocheville, M., Lange, D. C., Kumar, U., Patel, S. C., Patel, R. C. & Patel, Y. C. (2000) Science 288, 154-157.