-
1
-
-
0031984517
-
The many faces of G protein signaling
-
Hamm H.E. The many faces of G protein signaling. J. Biol. Chem. 273:1998;669-672.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 669-672
-
-
Hamm, H.E.1
-
2
-
-
0030987069
-
How receptors talk to trimeric G proteins
-
Bourne H.R. How receptors talk to trimeric G proteins. Curr. Opin. Cell Biol. 9:1997;134-142.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 134-142
-
-
Bourne, H.R.1
-
3
-
-
0032474767
-
G-protein diseases furnish a model for the turn-on switch
-
Iiri T., et al. G-protein diseases furnish a model for the turn-on switch. Nature. 394:1998;35-38.
-
(1998)
Nature
, vol.394
, pp. 35-38
-
-
Iiri, T.1
-
4
-
-
0029664589
-
The 2.0 Å crystal structure of a heterotrimeric G protein
-
Lambright D.G., et al. The 2.0 Å crystal structure of a heterotrimeric G protein. Nature. 379:1996;311-319.
-
(1996)
Nature
, vol.379
, pp. 311-319
-
-
Lambright, D.G.1
-
5
-
-
0029593456
-
i α1β1γ2
-
i α1β1γ2. Cell. 83:1995;1047-1058.
-
(1995)
Cell
, vol.83
, pp. 1047-1058
-
-
Wall, M.A.1
-
6
-
-
0030920782
-
G protein mechanisms: Insights from structural analysis
-
Sprang S.R. G protein mechanisms: insights from structural analysis. Annu. Rev. Biochem. 66:1997;639-678.
-
(1997)
Annu. Rev. Biochem.
, vol.66
, pp. 639-678
-
-
Sprang, S.R.1
-
7
-
-
0027132717
-
The 2.2 Å crystal structure of transducin-α complexed with GTP γS
-
Noel J.P., et al. The 2.2 Å crystal structure of transducin-α complexed with GTP γS. Nature. 366:1993;654-663.
-
(1993)
Nature
, vol.366
, pp. 654-663
-
-
Noel, J.P.1
-
8
-
-
0027733660
-
GTPases. A turn-on and a surprise
-
Bourne H.R. GTPases. A turn-on and a surprise. Nature. 366:1993;628-629.
-
(1993)
Nature
, vol.366
, pp. 628-629
-
-
Bourne, H.R.1
-
9
-
-
0028027596
-
GTPase mechanism of Gproteins from the 1.7 Å crystal structure of transducin α-GDP-AIF-4
-
Sondek J., et al. GTPase mechanism of Gproteins from the 1.7 Å crystal structure of transducin α-GDP-AIF-4. Nature. 372:1994;276-279.
-
(1994)
Nature
, vol.372
, pp. 276-279
-
-
Sondek, J.1
-
10
-
-
0030043913
-
Potent peptide analogues of a G protein receptor-binding region obtained with a combinatorial library
-
Martin E.L., et al. Potent peptide analogues of a G protein receptor-binding region obtained with a combinatorial library. J. Biol. Chem. 271:1996;361-366.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 361-366
-
-
Martin, E.L.1
-
11
-
-
0030614427
-
Receptor and βγ binding sites in the alpha subunit of the retinal G protein transducin
-
Onrust R., et al. Receptor and βγ binding sites in the alpha subunit of the retinal G protein transducin. Science. 275:1997;381-384.
-
(1997)
Science
, vol.275
, pp. 381-384
-
-
Onrust, R.1
-
12
-
-
0034636206
-
Coupling between the N- and C-terminal domains influences transducin-α intrinsic GDP/GTP exchange
-
Muradov K.G., Artemyev N.O. Coupling between the N- and C-terminal domains influences transducin-α intrinsic GDP/GTP exchange. Biochemistry. 39:2000;3937-3942.
-
(2000)
Biochemistry
, vol.39
, pp. 3937-3942
-
-
Muradov, K.G.1
Artemyev, N.O.2
-
13
-
-
0035834710
-
G protein gamma subunit interaction with a receptor regulates receptor-stimulated nucleotide exchange
-
Azpiazu I., Gautam N. G protein gamma subunit interaction with a receptor regulates receptor-stimulated nucleotide exchange. J. Biol. Chem. 276:2001;41742-41747.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41742-41747
-
-
Azpiazu, I.1
Gautam, N.2
-
14
-
-
0346755948
-
Rapid activation of transducin by mutations distant from the nucleotide-binding site: Evidence for a mechanistic model of receptor-catalyzed nucleotide exchange by G proteins
-
Marin E.P., et al. Rapid activation of transducin by mutations distant from the nucleotide-binding site: evidence for a mechanistic model of receptor-catalyzed nucleotide exchange by G proteins. J. Biol. Chem. 276:2001;27400-27405.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27400-27405
-
-
Marin, E.P.1
-
15
-
-
0037018839
-
Disruption of the α5 helix of transducin impairs rhodopsin - catalyzed nucleotide exchange
-
Marin E.P., et al. Disruption of the α5 helix of transducin impairs rhodopsin - catalyzed nucleotide exchange. Biochemistry. 41:2002;6988-6994.
-
(2002)
Biochemistry
, vol.41
, pp. 6988-6994
-
-
Marin, E.P.1
-
16
-
-
0032557490
-
Molecular basis for interactions of G protein βγ subunits with effectors
-
Ford C.E., et al. Molecular basis for interactions of G protein βγ subunits with effectors. Science. 280:1998;1271-1274.
-
(1998)
Science
, vol.280
, pp. 1271-1274
-
-
Ford, C.E.1
-
17
-
-
0001296931
-
Interactions between photoexcited rhodopsin and light-activated enzymes in rods
-
N. Osborne, & J. Chader. Pergamon press
-
Kühn H. Interactions between photoexcited rhodopsin and light-activated enzymes in rods. Osborne N., Chader J. Progress in Retinal Research. 1984;123-156 Pergamon press.
-
(1984)
Progress in Retinal Research
, pp. 123-156
-
-
Kühn, H.1
-
18
-
-
0035933167
-
Mutant G protein α subunit activated by Gβγ: A model for receptor activation?
-
Rondard P., et al. Mutant G protein α subunit activated by Gβγ: a model for receptor activation? Proc. Natl. Acad. Sci. U.S.A. 98:2001;6150-6155.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 6150-6155
-
-
Rondard, P.1
-
19
-
-
0035793567
-
A novel site on the Gα-protein that recognizes heptahelical receptors
-
Blahos J., et al. A novel site on the Gα-protein that recognizes heptahelical receptors. J. Biol. Chem. 276:2001;3262-3269.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3262-3269
-
-
Blahos, J.1
-
20
-
-
0030982264
-
Structure of RGS4 bound to AlF4-activated G(iα1): Stabilization of the transition state for GTP hydrolysis
-
Tesmer J.J., et al. Structure of RGS4 bound to AlF4-activated G(iα1): stabilization of the transition state for GTP hydrolysis. Cell. 89:1997;251-261.
-
(1997)
Cell
, vol.89
, pp. 251-261
-
-
Tesmer, J.J.1
-
21
-
-
0024427734
-
The transitory complex between photoexcited rhodopsin and transducin. Reciprocal interaction between the retinal site in rhodopsin and the nucleotide site in transducin
-
Bornancin F., et al. The transitory complex between photoexcited rhodopsin and transducin. Reciprocal interaction between the retinal site in rhodopsin and the nucleotide site in transducin. Eur. J. Biochem. 184:1989;687-698.
-
(1989)
Eur. J. Biochem.
, vol.184
, pp. 687-698
-
-
Bornancin, F.1
-
22
-
-
0032560850
-
The structural basis of the activation of Ras by Sos
-
Boriack-Sjodin P.A., et al. The structural basis of the activation of Ras by Sos. Nature. 394:1998;337-343.
-
(1998)
Nature
, vol.394
, pp. 337-343
-
-
Boriack-Sjodin, P.A.1
-
23
-
-
0032538317
-
Structural basis for activation of ARF GTPase: Mechanisms of guanine nucleotide exchange and GTP-myristoyl switching
-
Goldberg J. Structural basis for activation of ARF GTPase: mechanisms of guanine nucleotide exchange and GTP-myristoyl switching. Cell. 95:1998;237-248.
-
(1998)
Cell
, vol.95
, pp. 237-248
-
-
Goldberg, J.1
-
24
-
-
0034619877
-
Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1
-
Worthylake D.K., et al. Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1. Nature. 408:2000;682-688.
-
(2000)
Nature
, vol.408
, pp. 682-688
-
-
Worthylake, D.K.1
-
25
-
-
0035917523
-
Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1)
-
Renault L., et al. Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1). Cell. 105:2001;245-255.
-
(2001)
Cell
, vol.105
, pp. 245-255
-
-
Renault, L.1
-
26
-
-
0033179296
-
GEFs: Structural basis for their activation of small GTP-binding proteins
-
Cherfils J., Chardin P. GEFs: structural basis for their activation of small GTP-binding proteins. Trends Biochem. Sci. 24:1999;306-311.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 306-311
-
-
Cherfils, J.1
Chardin, P.2
-
27
-
-
0036866606
-
Arf, Arl, Arp and Sar proteins: A family of GTP-binding proteins with a structural device for front-back communication
-
Pasqualato S., et al. Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for front-back communication. EMBO Rep. 3:2002;1035-1041.
-
(2002)
EMBO Rep.
, vol.3
, pp. 1035-1041
-
-
Pasqualato, S.1
-
28
-
-
0027965652
-
i α1 and the mechanism of GTP hydrolysis
-
i α1 and the mechanism of GTP hydrolysis. Science. 265:1994;1405-1412.
-
(1994)
Science
, vol.265
, pp. 1405-1412
-
-
Coleman, D.E.1
-
29
-
-
0027741139
-
Separate GTP binding and GTPase activating domains of a Gα subunit
-
Markby D.W., et al. Separate GTP binding and GTPase activating domains of a Gα subunit. Science. 262:1993;1895-1901.
-
(1993)
Science
, vol.262
, pp. 1895-1901
-
-
Markby, D.W.1
-
30
-
-
0030025671
-
The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 Å resolution
-
Kawashima T., et al. The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 Å resolution. Nature. 379:1996;511-518.
-
(1996)
Nature
, vol.379
, pp. 511-518
-
-
Kawashima, T.1
-
31
-
-
0030764672
-
Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus
-
Wang Y., et al. Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus. Nat. Struct. Biol. 4:1997;650-656.
-
(1997)
Nat. Struct. Biol.
, vol.4
, pp. 650-656
-
-
Wang, Y.1
-
32
-
-
0033638335
-
Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Bα
-
Andersen G.R., et al. Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Bα Mol. Cell. 6:2000;1261-1266.
-
(2000)
Mol. Cell
, vol.6
, pp. 1261-1266
-
-
Andersen, G.R.1
-
33
-
-
0027530916
-
Selectivity in signal transduction determined by γ subunits of heterotrimeric G proteins
-
Kleuss C., et al. Selectivity in signal transduction determined by γ subunits of heterotrimeric G proteins. Science. 259:1993;832-834.
-
(1993)
Science
, vol.259
, pp. 832-834
-
-
Kleuss, C.1
-
34
-
-
0027435265
-
Specific interaction with rhodopsin is dependent on the γ subunit type in a G protein
-
Kisselev O., Gautam N. Specific interaction with rhodopsin is dependent on the γ subunit type in a G protein. J. Biol. Chem. 268:1993;24519-24522.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 24519-24522
-
-
Kisselev, O.1
Gautam, N.2
-
35
-
-
0034671531
-
Selective role of G protein γ subunits in receptor interaction
-
Hou Y., et al. Selective role of G protein γ subunits in receptor interaction. J. Biol. Chem. 275:2000;38961-38964.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38961-38964
-
-
Hou, Y.1
-
36
-
-
0028031159
-
Direct interaction of the α and γ subunits of the G proteins. Purification and analysis by limited proteolysis
-
Rahmatullah M., Robishaw J.D. Direct interaction of the α and γ subunits of the G proteins. Purification and analysis by limited proteolysis. J. Biol. Chem. 269:1994;3574-3580.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 3574-3580
-
-
Rahmatullah, M.1
Robishaw, J.D.2
-
37
-
-
0028870405
-
Specificity of G protein α-γ subunit interactions. N-terminal 15 amino acids of γ subunit specifies interaction with α subunit
-
Rahmatullah M., et al. Specificity of G protein α-γ subunit interactions. N-terminal 15 amino acids of γ subunit specifies interaction with α subunit. J. Biol. Chem. 270:1995;2946-2951.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2946-2951
-
-
Rahmatullah, M.1
-
38
-
-
0037171778
-
Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits
-
Kimple R.J., et al. Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits. Nature. 416:2002;878-881.
-
(2002)
Nature
, vol.416
, pp. 878-881
-
-
Kimple, R.J.1
-
39
-
-
0033181320
-
The GoLoco motif: A Gαi/o binding motif and potential guanine-nucleotide exchange factor
-
Siderovski D.P., et al. The GoLoco motif: a Gαi/o binding motif and potential guanine-nucleotide exchange factor. Trends Biochem. Sci. 24:1999;340-341.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 340-341
-
-
Siderovski, D.P.1
-
40
-
-
0035931919
-
Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 Å
-
Slep K.C., et al. Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 Å Nature. 409:2001;1071-1077.
-
(2001)
Nature
, vol.409
, pp. 1071-1077
-
-
Slep, K.C.1
-
41
-
-
0028862026
-
i α1 induced by GTP hydrolysis
-
i α1 induced by GTP hydrolysis. Science. 270:1995;954-960.
-
(1995)
Science
, vol.270
, pp. 954-960
-
-
Mixon, M.B.1
-
42
-
-
0031436245
-
Crystal structure of the adenylyl cyclase activator Gsα
-
Sunahara R.K., et al. Crystal structure of the adenylyl cyclase activator Gsα Science. 278:1997;1943-1947.
-
(1997)
Science
, vol.278
, pp. 1943-1947
-
-
Sunahara, R.K.1
-
43
-
-
0033966150
-
Mutagenesis in the switch IV of the helical domain of the human Gsα reduces its GDP/GTP exchange rate
-
Echeverria V., et al. Mutagenesis in the switch IV of the helical domain of the human Gsα reduces its GDP/GTP exchange rate. J. Cell. Biochem. 76:2000;368-375.
-
(2000)
J. Cell. Biochem.
, vol.76
, pp. 368-375
-
-
Echeverria, V.1
-
45
-
-
0030034646
-
Crystal structure of a G-protein βγ dimer at 2.1 Å resolution
-
Sondek J., et al. Crystal structure of a G-protein βγ dimer at 2.1 Å resolution. Nature. 379:1996;369-374.
-
(1996)
Nature
, vol.379
, pp. 369-374
-
-
Sondek, J.1
-
46
-
-
0032516098
-
Light-activated rhodopsin induces structural binding motif in G protein α subunit
-
Kisselev O.G., et al. Light-activated rhodopsin induces structural binding motif in G protein α subunit. Proc. Natl. Acad. Sci. U.S.A. 95:1998;4270-4275.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 4270-4275
-
-
Kisselev, O.G.1
-
47
-
-
0033593370
-
Crystal structure of intact elongation factor EF-Tu from Escherichia coli in GDP conformation at 2.05 Å resolution
-
Song H., et al. Crystal structure of intact elongation factor EF-Tu from Escherichia coli in GDP conformation at 2.05 Å resolution. J. Mol. Biol. 285:1999;1245-1256.
-
(1999)
J. Mol. Biol.
, vol.285
, pp. 1245-1256
-
-
Song, H.1
|