Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis

FEBS Journal

Volumn 274, Issue 8, 2007, Pages 1957-1969

  Siméone, Roxane ^a   Constant, Patricia ^a   Malaga, Wladimir ^a   Guilhot, Christophe ^a   Daffé, Mamadou ^a   Chalut, Christian ^a  

^a INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

Author keywords

Ketoreductase; Mycobacterium tuberculosis; Phenolic glycolipids; Phthiocerol dimycocerosates; Tuberculosis

Indexed keywords

LIPID; PHTHIOCEROL DIMYCOCEROSATE; PHTHIODIOLONE DIMYCOCEROSATE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL VIRULENCE; BIOSYNTHESIS; CATALYSIS; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME SUBSTRATE; GENE MUTATION; LIPOGENESIS; MOLECULAR MECHANICS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; BASE SEQUENCE; LIPIDS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PERMEABILITY; SODIUM DODECYL SULFATE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP; VIRULENCE;

MUS; MYCOBACTERIUM TUBERCULOSIS;

EID: 34247101599     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.05740.x     Document Type: Article

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