Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 19, 2002, Pages 12120-12125

  May, Jürgen J ^a   Kessler, Nadine ^a   Marahiel, Mohamed A ^a   Stubbs, Milton T ^b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Adenylation domain; Antibiotic biosynthesis; Nonribosomal peptide synthesis; Siderophore formation; X ray crystal structure

Indexed keywords

2,3 DIHYDROXYBENZOIC ACID; ACID; ADENOSINE PHOSPHATE; LIGAND; LONG CHAIN FATTY ACID COENZYME A LIGASE; LUCIFERASE; PEPTIDE SYNTHASE; PHOSPHATE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PROTEIN DERIVATIVE; PROTEIN DHBE; SIDEROPHORE; UNCLASSIFIED DRUG;

ADENYLATION; AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME SUBSTRATE; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS;

ADENOSINE MONOPHOSPHATE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BACILLUS SUBTILIS; CATALYTIC DOMAIN; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; ESTERS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PEPTIDE SYNTHASES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

NEGIBACTERIA;

EID: 0037126024     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.182156699     Document Type: Article

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