AStat5b transgene is capable of inducing CD8+ lymphoblastic lymphoma in the absence of normal TCR/MHC signaling

Blood

Volumn 111, Issue 1, 2008, Pages 344-350

  Bessette, Katherine ^a,b   Lang, Mark L ^b   Fava, Roy A ^a,b   Grundy, Martin ^a   Heinen, Jennifer ^a   Horne, Laurie ^b   Spolski, Rosanne ^c   Al Shami, Amin ^c   Morse III, Herbert C ^d   Leonard, Warren J ^c   Kelly, John A ^a,b,e  

^a Veterans Affairs White River Junction Health Care System   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e 2 123 Building 44   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; STAT5 PROTEIN; STAT5A PROTEIN; STAT5B PROTEIN; T LYMPHOCYTE RECEPTOR; TYROSINE; LYMPHOCYTE ANTIGEN RECEPTOR; STAT5B PROTEIN, MOUSE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CARCINOGENICITY; CD8+ T LYMPHOCYTE; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; DOUBLE NEGATIVE STAGE; DOUBLE POSITIVE STAGE; IMMUNE SYSTEM; IMMUNIZATION; LYMPHOBLASTOMA; LYMPHOCYTE; MAJOR HISTOCOMPATIBILITY COMPLEX; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STAT5B GENE; T LYMPHOCYTE; THYMOCYTE; TRANSGENE; TRANSGENIC MOUSE; TUMOR GROWTH; ANIMAL; CELL TRANSFORMATION; GENETICS; IMMUNOLOGY; LYMPHATIC LEUKEMIA; METABOLISM; NATURAL KILLER CELL; PATHOLOGY; PHYSIOLOGY;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL TRANSFORMATION, NEOPLASTIC; KILLER CELLS, NATURAL; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, TRANSGENIC; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; T-LYMPHOCYTES; TRANSGENES;

EID: 38049162276     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2007-04-084707     Document Type: Article

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