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Volumn 4, Issue 1, 2006, Pages 39-45

A constitutively active Lck kinase promotes cell proliferation and resistance to apoptosis through signal transducer and activator of transcription 5b activation

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 3; PROTEIN KINASE LCK; STAT PROTEIN; STAT5B PROTEIN; TETRACYCLINE;

EID: 32944462153     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-05-0202     Document Type: Article
Times cited : (29)

References (41)
  • 1
    • 0025881652 scopus 로고
    • The lck tyrosine protein kinase
    • Sefton BM. The lck tyrosine protein kinase. Oncogene 1991;6:683-6.
    • (1991) Oncogene , vol.6 , pp. 683-686
    • Sefton, B.M.1
  • 2
    • 7944231534 scopus 로고    scopus 로고
    • Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation
    • Palacios EH, Weiss A. Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation. Oncogene 2004;23:7990-8000.
    • (2004) Oncogene , vol.23 , pp. 7990-8000
    • Palacios, E.H.1    Weiss, A.2
  • 4
    • 0006616576 scopus 로고
    • Localization of a lymphocyte-specific protein tyrosine kinase gene (lck) at a site of frequent chromosomal abnormalities in human lymphomas
    • Marth JD, Disteche C, Pravtcheva D, et al. Localization of a lymphocyte-specific protein tyrosine kinase gene (lck) at a site of frequent chromosomal abnormalities in human lymphomas. Proc Natl Acad Sci U S A 1986;83:7400-4.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 7400-7404
    • Marth, J.D.1    Disteche, C.2    Pravtcheva, D.3
  • 5
    • 0028353897 scopus 로고
    • Oncogenic activation of the Lck protein accompanies translocation of the LCK gene in the human HSB2 T-cell leukemia
    • Wright DD, Sefton BM, Kamps MP. Oncogenic activation of the Lck protein accompanies translocation of the LCK gene in the human HSB2 T-cell leukemia. Mol Cell Biol 1994;14:2429-37.
    • (1994) Mol Cell Biol , vol.14 , pp. 2429-2437
    • Wright, D.D.1    Sefton, B.M.2    Kamps, M.P.3
  • 6
    • 0032733617 scopus 로고    scopus 로고
    • Dysregulation of the protein tyrosine kinase Lck in lymphoproliferative disorders and in other neoplasias
    • Majolini MB, Boncristiano M, Baldari CT. Dysregulation of the protein tyrosine kinase Lck in lymphoproliferative disorders and in other neoplasias. Leuk Lymphoma 1999;35:245-54.
    • (1999) Leuk Lymphoma , vol.35 , pp. 245-254
    • Majolini, M.B.1    Boncristiano, M.2    Baldari, C.T.3
  • 7
  • 8
    • 7944223078 scopus 로고    scopus 로고
    • Structure and regulation of Src family kinases
    • Boggon TJ, Eck MJ. Structure and regulation of Src family kinases. Oncogene 2004;23:7918-27.
    • (2004) Oncogene , vol.23 , pp. 7918-7927
    • Boggon, T.J.1    Eck, M.J.2
  • 9
    • 0023867607 scopus 로고
    • Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck)
    • Marth JD, Cooper JA, King CS, et al. Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck). Mol Cell Biol 1988;8:540-50.
    • (1988) Mol Cell Biol , vol.8 , pp. 540-550
    • Marth, J.D.1    Cooper, J.A.2    King, C.S.3
  • 11
    • 1042302005 scopus 로고    scopus 로고
    • The STATs of cancer-new molecular target come of age
    • Yu H, Jove R. The STATs of cancer-new molecular target come of age. Nat Rev Cancer 2004;4:97-105.
    • (2004) Nat Rev Cancer , vol.4 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 12
    • 0036251154 scopus 로고    scopus 로고
    • Stat proteins and oncogenesis
    • Bromberg J. Stat proteins and oncogenesis. J Clin Invest 2002;109:1139-42.
    • (2002) J Clin Invest , vol.109 , pp. 1139-1142
    • Bromberg, J.1
  • 13
    • 0036731485 scopus 로고    scopus 로고
    • Stats: Transcriptional control and biological impact
    • Levy DE, Darnell JE. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002;3:651-62.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell, J.E.2
  • 14
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
    • O'Shea JJ, Gadina M, Schreiber RD. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 2002;109:8121-31.
    • (2002) Cell , vol.109 , pp. 8121-8131
    • O'Shea, J.J.1    Gadina, M.2    Schreiber, R.D.3
  • 15
    • 0035313701 scopus 로고    scopus 로고
    • The Stat family in cytokine signaling
    • Ihle JN. The Stat family in cytokine signaling. Curr Opin Cell Biol 2001;13:211-7.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 211-217
    • Ihle, J.N.1
  • 16
    • 18544372618 scopus 로고    scopus 로고
    • Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells
    • Sonoyama J, Matsumura I, Ezoe S, et al. Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells. J Biol Chem 2002;277:8076-82.
    • (2002) J Biol Chem , vol.277 , pp. 8076-8082
    • Sonoyama, J.1    Matsumura, I.2    Ezoe, S.3
  • 17
    • 0031806306 scopus 로고    scopus 로고
    • Involvement of prolonged Ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line
    • Matsumura I, Nakajima K, Wakao H, et al. Involvement of prolonged Ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line. Mol Cell Biol 1998;18:4282-90.
    • (1998) Mol Cell Biol , vol.18 , pp. 4282-4290
    • Matsumura, I.1    Nakajima, K.2    Wakao, H.3
  • 18
    • 0141567775 scopus 로고    scopus 로고
    • Growth hormone insensitivity associated with a STAT5b mutation
    • Kofoed EM, Hwa V, Little B, et al. Growth hormone insensitivity associated with a STAT5b mutation. N Engl J Med 2003;349:1139-47.
    • (2003) N Engl J Med , vol.349 , pp. 1139-1147
    • Kofoed, E.M.1    Hwa, V.2    Little, B.3
  • 19
    • 9244243110 scopus 로고    scopus 로고
    • STATs as critical mediators of signal transduction and transcription: Lessons learned from STAT5
    • Paukku K, Silvennoinen O. STATs as critical mediators of signal transduction and transcription: lessons learned from STAT5. Cytokine Growth Factor Rev 2004;15:435-55.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 435-455
    • Paukku, K.1    Silvennoinen, O.2
  • 20
    • 0032831735 scopus 로고    scopus 로고
    • Stat5a and Stat5b: Fraternal twins of signal transduction and transcriptional activation
    • Grimley PM, Dong F, Rui H. Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation. Cytokine Growth Factor Rev 1999;10:131-57.
    • (1999) Cytokine Growth Factor Rev , vol.10 , pp. 131-157
    • Grimley, P.M.1    Dong, F.2    Rui, H.3
  • 21
  • 22
    • 0033529715 scopus 로고    scopus 로고
    • Differential effects of prolactin and src/abl kinases on the nuclear translocation of STAT5B and STAT5A
    • Kazansky AV, Kabotyanski EB, Wyszomierski SL, Mancini MA, Rosen JM. Differential effects of prolactin and src/abl kinases on the nuclear translocation of STAT5B and STAT5A. J Biol Chem 1999;274:22484-92.
    • (1999) J Biol Chem , vol.274 , pp. 22484-22492
    • Kazansky, A.V.1    Kabotyanski, E.B.2    Wyszomierski, S.L.3    Mancini, M.A.4    Rosen, J.M.5
  • 23
    • 0035141924 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription 5B potentiates v-Src-mediated transformation of NIH-3T3 cells
    • Kazansky AV, Rosen JM. Signal transducers and activators of transcription 5B potentiates v-Src-mediated transformation of NIH-3T3 cells. Cell Growth Differ 2001;12:1-7.
    • (2001) Cell Growth Differ , vol.12 , pp. 1-7
    • Kazansky, A.V.1    Rosen, J.M.2
  • 24
    • 0035419348 scopus 로고    scopus 로고
    • Role of signal transducer and activator of transcription 5 in nucleophosmin/anaplastic lymphoma kinase-mediated malignant transformation of lymphoid cells
    • Nieborowska-Skorska M, Slupianek A, Xue L, et al. Role of signal transducer and activator of transcription 5 in nucleophosmin/anaplastic lymphoma kinase-mediated malignant transformation of lymphoid cells. Cancer Res 2001;61:6517-23.
    • (2001) Cancer Res , vol.61 , pp. 6517-6523
    • Nieborowska-Skorska, M.1    Slupianek, A.2    Xue, L.3
  • 25
    • 0142219889 scopus 로고    scopus 로고
    • Constitutive activation of Stat5b contributes to carcinogenesis in vivo
    • Xi S, Zhang Q, Gooding WE, Smithgall TE, Grandis JR. Constitutive activation of Stat5b contributes to carcinogenesis in vivo. Cancer Res 2003;63:6763-71.
    • (2003) Cancer Res , vol.63 , pp. 6763-6771
    • Xi, S.1    Zhang, Q.2    Gooding, W.E.3    Smithgall, T.E.4    Grandis, J.R.5
  • 26
    • 85047696110 scopus 로고    scopus 로고
    • Differential function of STAT5 isoforms in head and neck cancer growth control
    • Leong PL, Xi S, Drenning SD, et al. Differential function of STAT5 isoforms in head and neck cancer growth control. Oncogene 2002;21:2846-53.
    • (2002) Oncogene , vol.21 , pp. 2846-2853
    • Leong, P.L.1    Xi, S.2    Drenning, S.D.3
  • 27
    • 0033534384 scopus 로고    scopus 로고
    • STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation
    • Welte T, Leitenberg D, Dittel BN, et al. STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation. Science 1999;283:222-5.
    • (1999) Science , vol.283 , pp. 222-225
    • Welte, T.1    Leitenberg, D.2    Dittel, B.N.3
  • 28
    • 0029069540 scopus 로고
    • Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
    • Yu C-L, Meyer DJ, Campbell GS, et al. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 1995;269:81-3.
    • (1995) Science , vol.269 , pp. 81-83
    • Yu, C.-L.1    Meyer, D.J.2    Campbell, G.S.3
  • 29
    • 32144451145 scopus 로고    scopus 로고
    • Characterization of STAT5B phosphorylation correlating with expression of cytokine-inducible SH2-containing protein (CIS)
    • In press
    • Cooper JC, Boustead JN, Yu C-L. Characterization of STAT5B phosphorylation correlating with expression of cytokine-inducible SH2-containing protein (CIS). Cell Signal. In press 2006.
    • (2006) Cell Signal
    • Cooper, J.C.1    Boustead, J.N.2    Yu, C.-L.3
  • 30
    • 0034653478 scopus 로고    scopus 로고
    • Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells
    • Lacronique V, Boureux A, Monni R, et al. Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells. Blood 2000;95:2076-83.
    • (2000) Blood , vol.95 , pp. 2076-2083
    • Lacronique, V.1    Boureux, A.2    Monni, R.3
  • 31
    • 0033120870 scopus 로고    scopus 로고
    • Constitutive activation of the JAK2/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell lines
    • Liu RY, Fan C, Garcia R, Jove R, Zuckerman KS. Constitutive activation of the JAK2/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell lines. Blood 1999;93:2369-79.
    • (1999) Blood , vol.93 , pp. 2369-2379
    • Liu, R.Y.1    Fan, C.2    Garcia, R.3    Jove, R.4    Zuckerman, K.S.5
  • 32
    • 0035950439 scopus 로고    scopus 로고
    • Specific DNA binding and transactivation potential of recombinant, purified Stat5
    • Beisenherz-Huss C, Mundt M, Herrala A, et al. Specific DNA binding and transactivation potential of recombinant, purified Stat5. Mol Cell Endocrinol 2001;183:101-12.
    • (2001) Mol Cell Endocrinol , vol.183 , pp. 101-112
    • Beisenherz-Huss, C.1    Mundt, M.2    Herrala, A.3
  • 33
    • 0032704818 scopus 로고    scopus 로고
    • The Src-family kinase Lck can induce STAT3 phosphorylation and DNA binding activity
    • Lund TC, Coleman C, Horvath E, et al. The Src-family kinase Lck can induce STAT3 phosphorylation and DNA binding activity. Cell Signal 1999;11:789-96.
    • (1999) Cell Signal , vol.11 , pp. 789-796
    • Lund, T.C.1    Coleman, C.2    Horvath, E.3
  • 34
    • 0036560577 scopus 로고    scopus 로고
    • Oncogenic tyrosine kinases and the DNA-damage response
    • Skorski T. Oncogenic tyrosine kinases and the DNA-damage response. Nat Rev Cancer 2002;2:351-60.
    • (2002) Nat Rev Cancer , vol.2 , pp. 351-360
    • Skorski, T.1
  • 36
    • 0028625746 scopus 로고
    • A rapid and simple method for the isolation of apoptotic DNA fragments
    • Herrmann M, Lorenz HM, Voll R, et al. A rapid and simple method for the isolation of apoptotic DNA fragments. Nucleic Acids Res 1994;22:5506-7.
    • (1994) Nucleic Acids Res , vol.22 , pp. 5506-5507
    • Herrmann, M.1    Lorenz, H.M.2    Voll, R.3
  • 37
    • 0034650805 scopus 로고    scopus 로고
    • Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation
    • Kieslinger M, Woldman I, Moriggl R, et al. Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation. Genes Dev 2000;14:232-44.
    • (2000) Genes Dev , vol.14 , pp. 232-244
    • Kieslinger, M.1    Woldman, I.2    Moriggl, R.3
  • 38
    • 0034972913 scopus 로고    scopus 로고
    • Interleukin-2 inhibits glucocorticoid receptor transcriptional activity through a mechanism involving STAT5 (signal transducer and activator of transcription 5) but not AP-1
    • Biola A, Lefebvre P, Perrin-Wolff M, et al. Interleukin-2 inhibits glucocorticoid receptor transcriptional activity through a mechanism involving STAT5 (signal transducer and activator of transcription 5) but not AP-1. Mol Endocrinol 2001;15:1062-76.
    • (2001) Mol Endocrinol , vol.15 , pp. 1062-1076
    • Biola, A.1    Lefebvre, P.2    Perrin-Wolff, M.3
  • 39
    • 0031306869 scopus 로고    scopus 로고
    • Constitutive activation of the Janus kinase-STAT pathway in T lymphoma overexpressing the Lck protein tyrosine kinase
    • Yu C-L, Jove R, Burakoff SJ. Constitutive activation of the Janus kinase-STAT pathway in T lymphoma overexpressing the Lck protein tyrosine kinase. J Immunol 1997;159:5206-10.
    • (1997) J Immunol , vol.159 , pp. 5206-5210
    • Yu, C.-L.1    Jove, R.2    Burakoff, S.J.3
  • 40
    • 7944237784 scopus 로고    scopus 로고
    • The interplay between Src family kinases and receptor tyrosine kinases
    • Bromann PA, Korkaya H, Courtneidge SA. The interplay between Src family kinases and receptor tyrosine kinases. Oncogene 2004;23:7957-68.
    • (2004) Oncogene , vol.23 , pp. 7957-7968
    • Bromann, P.A.1    Korkaya, H.2    Courtneidge, S.A.3
  • 41
    • 0034614626 scopus 로고    scopus 로고
    • Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation
    • Yu C-L, Jin YJ, Burakoff SJ. Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation. J Biol Chem 2000;275:599-604.
    • (2000) J Biol Chem , vol.275 , pp. 599-604
    • Yu, C.-L.1    Jin, Y.J.2    Burakoff, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.