Flow cytometry in the diagnosis of mediastinal tumors with emphasis on differentiating thymocytes from precursor T-lymphoblastic lymphoma/leukemia

Leukemia and Lymphoma

Volumn 45, Issue 3, 2004, Pages 529-538

  Gorczyca, Wojciech ^a   Tugulea, Sorina ^a   Liu, Zach ^a   Li, Xiaoyu ^a   Wong, John Y L ^a   Weisberger, James ^a  

^a IMPATH Inc   (United States)

Author keywords

Flow cytometry; Immunophenotyping; Mediastinum; T lymphoblastic lymphoma; Thymocytes; Thymoma

Indexed keywords

CD3 ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; B CELL LYMPHOMA; CELL MATURATION; CELL SUSPENSION; CELL VIABILITY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FLOW CYTOMETRY; HEMATOPOIETIC SYSTEM TUMOR; HISTOPATHOLOGY; HODGKIN DISEASE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LYMPHATIC LEUKEMIA; LYMPHOBLASTOMA; MAJOR CLINICAL STUDY; MEDIASTINUM TUMOR; MEDICAL ASSESSMENT; METHODOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROLYMPHOCYTE; SENSITIVITY ANALYSIS; SUPERIOR CAVA VEIN SYNDROME; T CELL LYMPHOMA; T LYMPHOCYTE; THYMOCYTE; THYMOMA; THYMUS HYPERPLASIA; TIME; TUMOR LOCALIZATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CELL DIFFERENTIATION; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOPHENOTYPING; LEUKEMIA, LYMPHOCYTIC; LEUKEMIA, T-CELL, ACUTE; LYMPH NODES; MALE; MEDIASTINAL NEOPLASMS; MIDDLE AGED; MOLECULAR DIAGNOSTIC TECHNIQUES; THYMUS GLAND;

EID: 1042280343     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.1080/10428190310001598008     Document Type: Article

References (27)

1. Shimosato, Y. and Mukai, K. editors. (1997) "Tumors of the mediastinum", Atlas of Tumor Pathology. 3rd series. Washington: AFIP.
2. Tumors of Hematopoietic and Lymphoid Tissues. WHO classification of hematolymphoid neoplasms. (2001) Edited by E.S. Jaffe, N.L Harris, H. Stein and J.W. Vardiman. Lyon: IARC Press.
3. Cazals-Hatem, D., Lepage, E., Brice, P., Ferrant, A., d'Agay, M.F., Baumelou, E., et al. (1996) "Primary mediastinal B-cell lymphoma. A clinicopathologic study of 141 cases compared with 916 nonmediastinal large B-cell lymphomas, a GELA study", American Journal of Surgical Pathology, 20, 877-888.
4. Suster, S. (1999) "Primary large-cell lymphoma of the mediastinum", Seminars in Diagnostic Pathology, 16, 51-64.
5. Addis, B.J. and Isaacson, P.G. (1986) "Large cell lymphoma of the mediastinum a B-cell tumor of probable thymic origin", Histopathology, 10, 376-390.
6. Al-Sharabati, M., Chittal, S., Duga-Neulat, I., Laurent, G., Mazerolles, C., Al-Saati, T., et al. (1991) "Primary anterior mediastinal B-cell lymphoma. A clinicopathologic and immunohistochemical study of 16 cases", Cancer, 67, 2579-2587.
7. Suster, S. and Moran, C.A. (1996) "Pleomorphic large cell lymphomas of the mediastinum", American Journal of Pathology, 20, 224-232.
8. Maryniak, R.K. and Roszkowska-Purska, K. (2002) "Primary mediastinal large B-cell lymphoma is an important differential among mediastinal tumors", Polish Journal of Pathology, 53, 139-144.
9. Weidner, N. (1999) "Germ-cell tumors of the mediastinum", Seminars in Diagnostic Pathology, 16, 42-50.
10. de Level, L., Ferry, J.A., Falini, B., Shipp, M. and Harris, N.L. (2001) "Expression of bcl-6 and CD10 in primary mediastinal large B-cell lymphoma. Evidence for derivation from germinal center B cells"? American Journal of Surgery Pathology, 25, 1277-1282.
11. Scarpa, A., Moore, P.S., Rigaud, G. and Menestrina, F. (2001) "Genetic alterations in primary mediastinal B-cell lymphoma: An update", Leukemia and Lymphoma, 41, 47-53.
12. Parrens, M., Dubus, P., Danjoux, M., Jougon, J., Brousset, P., Velly, J. F., et al. (2002) "Mucosa-associated lymphoid tissue of the thymus. Hyperplasia versus lymphoma", American Journal of Clinical Pathology, 117, 51-56.
13. Inagaki, H., Chan, J.K.C., Ng, J.W.M., Okabe, M., Yoshino, T., Yokose, T., et al. (2002) "Primary thymic extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue type exhibits distinctive clinicopathological and molecular features", American Journal of Pathology, 160, 1435-1443.
14. Copie-Bergman, C., Plonquet, A., Alonso, M.A., Boulland, M.L., Marquet, J., Divine, M., et al. (2002) "MAL expression in lymphoid cells: further evidence for MAL as a distinct molecular marker of primary mediastinal large B-cell lymphomas", Modern Pathology, 15, 1172-1180.
15. Jennings, C.D. and Foon, K.A. (1997) "Recent advances in flow cytometry: application to the diagnosis of hematologic malignancy", Blood, 90, 2863-2892.
16. Davis, B.H., Foucar, K., Szczarkowski, W., Ball, E., Witzig, T., Foon, K.A., et al. (1997) "U.S.-Canadian consensus recommendations on the immunophenotypic analysis of hematologic neoplasia by flow cytometry", Cytometry, 30, 249-263.
17. Weisberger, J., Wu, C.D., Liu, Z., Wong, J.Y., Melamed, M.R., Darzynkiewiez, Z., et al. (2000) "Differential diagnosis of malignant lymphomas and related disorders by specific pattern of expression of immunophenotypic markers revealed by multiparameter flow cytometry (Review)", International Journal of Oncology, 17, 1165-1177.
18. Gorczyca, W., Weisberger, J., Liu, Z., Tsang, P., Hossein, M., Wu, C.D., et al. (2002) "An approach to diagnosis of T-cell lymphoproliferative disorders by flow cytometry", Cytometry (Clinical Cytometry), 50, 177-190.
19. Knowles, D.M. (2001) Immunophenotypic markers useful in the diagnosis and classification of hematopoietic neoplasms. In: Neoplastic Hematopathology. 2nd edition, edited by D.M. Knowles. Philadelphia: Lippincott Williams and Wilkins.
20. Morse, E.E., Yamase, H.T., Greenberg, B.R., Sporn, J., Harshaw, S.A., Kiraly, T.R., et al. (1994) "The role of flow cytometry in the diagnosis of lymphoma: a critical analysis", Annals of Clinical and Laboratory Science, 24, 6-11.
21. Dunphy, C.H. (2000) "Contribution of flow cytometric immunophenotyping to the evaluation of tissues with suspected lymphoma"? Cytometry, 42, 296-306.
22. Knowles, D.M. (2001) Lymphoblastic lymphoma. In: Neoplastic Hematopathology. 2nd edition, edited by D.M. Knowles. Philadelphia: Lippincott Williams and Wilkins.
23. Roper, M., Crist, W.M., Metzgar, R., Ragab, A.H., Smith, S., Starling, K., et al. (1983) "Monoclonal antibody characterization of surface antigens in childhood T-cell lymphoid malignancies", Blood, 61, 830-837.
24. Scheibani, K., Nathwani, B.N., Winberg, C.D., Burke, J.S., Swartz, W.G., Blayney, D., et al. (1987) "Antigenically defined subgroups of lymphoblastic lymphoma. Relationship to clinical presentation and biologic behavior", Cancer, 60, 183-190.
25. Mori, N., Oka, K., Yoda, Y., Abe, T. and Kojima, M. (1988) "Leu-4 (CD3) antigen expression in the neoplastic cells from T-ALL and T-lymphoblastic, lymphoma", American Journal of Clinical Pathology, 90, 244-249.
26. Fujii, Y., Okumura, M. and Yamamoto, S. (1999) "Flow cytometric study of lymphocytes associated with thymoma and other thymic tumors", Journal of Surgical Research, 82, 312-318.
27. Nakajima, J., Takamoto, S., Kohno, T., Ohtsuka, T. and Matsumoto, J. (1999) "Expression of CD10 on lymphoid cells associated with thymoma", Japanese Journal of Thoracic Cardiovascular Surgery, 47, 68-72.