PKCθ mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia

Oncogene

Volumn 24, Issue 6, 2005, Pages 992-1000

  Felli, Maria Pia ^a   Vacca, Alessandra ^a   Calce, Angelica ^a   Bellavia, Diana ^a   Campese, Antonio F ^a   Grillo, Rita ^a   Di Giovine, Monica ^b   Checquolo, Saula ^a   Talora, Claudio ^a   Palermo, Rocco ^b   Di Mario, Giuseppina ^a   Frati, Luigi ^a,c   Gulino, Alberto ^a,c   Screpanti, Isabella ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF L'AQUILA   (Italy)

^c IRCCS NEUROMED   (Italy)

Author keywords

Leukemia; NF B; Notch3; PKC ; T cells

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NOTCH3 RECEPTOR; PROTEIN KINASE C THETA; T LYMPHOCYTE RECEPTOR; CELL SURFACE RECEPTOR; ISOENZYME; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; NOTCH RECEPTOR; NOTCH3 PROTEIN, MOUSE; NOTCH4 PROTEIN, MOUSE; ONCOPROTEIN; PRE T CELL RECEPTOR ALPHA; PRE-T CELL RECEPTOR ALPHA; PRKCQ PROTEIN, HUMAN; PROTEIN KINASE C; ZINC FINGER PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER MODEL; CARCINOGENESIS; CONTROLLED STUDY; GENE DELETION; LYMPHOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T CELL LEUKEMIA; T CELL LYMPHOMA; T LYMPHOCYTE ACTIVATION; THYMOCYTE; TRANSGENIC MOUSE; ANIMAL; CELL MEMBRANE; CYTOLOGY; GENETICS; PATHOPHYSIOLOGY; THYMUS;

ANIMALS; CELL MEMBRANE; ISOENZYMES; LEUKEMIA, T-CELL; LYMPHOMA, T-CELL; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; NF-KAPPA B; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, CELL SURFACE; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; THYMUS GLAND; ZINC FINGERS;

EID: 13944266008     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208302     Document Type: Article

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