High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias

Journal of Lipid Research

Volumn 49, Issue 1, 2008, Pages 230-244

  Li, Hong ^a   Black, Paul N ^a   Chokshi, Aalap ^a   Sandoval Alvarez, Angel ^a   Vatsyayan, Ravi ^a   Sealls, Whitney ^a   DiRusso, Concetta C ^a  

^a ORDWAY RESEARCH INSTITUTE   (United States)

Author keywords

4,4 difluoro 5 methyl 4 bora 3a,4a diaza s indacene 3 dodecanoic acid; Caco 2; Fatty acid transport protein; Yeast

Indexed keywords

4,4 DIFLUORO 5 METHYL 4 BORA 3A,4A DIAZA S INDACENE 3 DODECANOIC ACID; FATTY ACID DERIVATIVE; FATTY ACID TRANSPORTER; FATTY ACID TRANSPORTER 2; NEUROLEPTIC AGENT; PHENOTHIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DYSLIPIDEMIA; FATTY ACID SYNTHESIS; FATTY ACID TRANSPORT; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HYPERTRIGLYCERIDEMIA; MENTAL DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHIZOPHRENIA; YEAST;

ANTIPSYCHOTIC AGENTS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; DRUG EVALUATION, PRECLINICAL; DYSLIPIDEMIAS; FATTY ACID TRANSPORT PROTEINS; FATTY ACIDS; FRUCTOSE; HUMANS; SACCHAROMYCES CEREVISIAE; SMALL MOLECULE LIBRARIES;

EID: 38049141096     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.D700015-JLR200     Document Type: Article

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