Deorphanisation of G protein-coupled receptors: A tool to provide new insights in nervous system pathophysiology and new targets for psycho-active drugs

Neurochemistry International

Volumn 52, Issue 3, 2008, Pages 339-351

  Lecca, Davide ^a   Abbracchio, Maria P ^a  

^a Faculty of Pharmacy   (Italy)

Author keywords

Central nervous system; Deorphanisation; GPCRs; Psycho active drugs

Indexed keywords

2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE; ANTISENSE OLIGODEOXYNUCLEOTIDE; CANGRELOR; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 17; G PROTEIN COUPLED RECEPTOR 37; G PROTEIN COUPLED RECEPTOR 50; MONTELUKAST; NEUROMEDIN S; NEUROPEPTIDE; PRANLUKAST; PURINERGIC P2Y RECEPTOR; PURINERGIC P2Y RECEPTOR 14; UNCLASSIFIED DRUG;

ANXIETY; BRAIN DAMAGE; BRAIN ISCHEMIA; CIRCADIAN RHYTHM; DEGENERATIVE DISEASE; DEPRESSION; DRUG MECHANISM; DRUG TARGETING; GENE LOCATION; GENE MAPPING; GENE MUTATION; HUMAN; INFECTION; INFLAMMATION; MENTAL DISEASE; MOLECULAR CLONING; NEUROPROTECTION; NONHUMAN; PAIN; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PSYCHOSIS; REGULATOR GENE; REVIEW; SCHIZOPHRENIA; SHY DRAGER SYNDROME; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; BRAIN CHEMISTRY; CENTRAL NERVOUS SYSTEM; DRUG DESIGN; HUMANS; LIGANDS; NERVOUS SYSTEM DISEASES; NEUROPEPTIDES; PSYCHOTROPIC DRUGS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 38049014833     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2007.08.002     Document Type: Review

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