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Volumn 5, Issue 12, 2007, Pages 1319-1330

Phosphorylation of Sp1 in response to DNA damage by ataxia telangiectasia-mutated kinase

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ATM PROTEIN; DOUBLE STRANDED DNA; HISTONE H2AX; HYDROGEN PEROXIDE; SERINE; TRANSCRIPTION FACTOR SP1;

EID: 37849024621     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-07-0374     Document Type: Article
Times cited : (78)

References (76)
  • 1
    • 0021058853 scopus 로고
    • The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter
    • Dynan WS, Tjian R. The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter. Cell 1983;35:79-87.
    • (1983) Cell , vol.35 , pp. 79-87
    • Dynan, W.S.1    Tjian, R.2
  • 2
    • 0022343345 scopus 로고
    • Sp1 binds to promoter sequences and activates herpes simplex virus 'immediate-early' gene transcription in vitro
    • Jones KA, Tjian R. Sp1 binds to promoter sequences and activates herpes simplex virus 'immediate-early' gene transcription in vitro. Nature 1985;317:179-82.
    • (1985) Nature , vol.317 , pp. 179-182
    • Jones, K.A.1    Tjian, R.2
  • 3
    • 0023663884 scopus 로고
    • Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain
    • Kadonaga JT, Carner KR, Masiarz FR, Tjian R. Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell 1987;51:1079-90.
    • (1987) Cell , vol.51 , pp. 1079-1090
    • Kadonaga, J.T.1    Carner, K.R.2    Masiarz, F.R.3    Tjian, R.4
  • 4
    • 0030853287 scopus 로고    scopus 로고
    • Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation
    • Marin M, Karis A, Visser P, Grosveld F, Philipsen S. Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation. Cell 1997;89:619-28.
    • (1997) Cell , vol.89 , pp. 619-628
    • Marin, M.1    Karis, A.2    Visser, P.3    Grosveld, F.4    Philipsen, S.5
  • 6
    • 0021687959 scopus 로고
    • Multiple specific contacts between a mammalian transcription factor and its cognate promoters
    • Gidoni D, Dynan WS, Tjian R. Multiple specific contacts between a mammalian transcription factor and its cognate promoters. Nature 1984;312:409-13.
    • (1984) Nature , vol.312 , pp. 409-413
    • Gidoni, D.1    Dynan, W.S.2    Tjian, R.3
  • 8
    • 0027406964 scopus 로고
    • Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators
    • Hoey T, Weinzierl RO, Gill G, Chen JL, Dynlacht BD, Tjian R. Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators. Cell 1993;72:247-60.
    • (1993) Cell , vol.72 , pp. 247-260
    • Hoey, T.1    Weinzierl, R.O.2    Gill, G.3    Chen, J.L.4    Dynlacht, B.D.5    Tjian, R.6
  • 9
    • 0030447651 scopus 로고    scopus 로고
    • Molecular cloning and analysis of two subunits of the human TFIIDcomp lex: HTAFII130 and hTAFII100
    • Tanese N, Saluja D, Vassallo MF, Chen JL, Admon A. Molecular cloning and analysis of two subunits of the human TFIIDcomp lex: hTAFII130 and hTAFII100. Proc Natl Acad Sci U S A 1996;93:13611-6.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 13611-13616
    • Tanese, N.1    Saluja, D.2    Vassallo, M.F.3    Chen, J.L.4    Admon, A.5
  • 10
    • 33846214719 scopus 로고    scopus 로고
    • Prevalence of the initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATA-less core promoters
    • Yang C, Bolotin E, Jiang T, Sladek FM, Martinez E. Prevalence of the initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATA-less core promoters. Gene 2007;389:52-65.
    • (2007) Gene , vol.389 , pp. 52-65
    • Yang, C.1    Bolotin, E.2    Jiang, T.3    Sladek, F.M.4    Martinez, E.5
  • 11
    • 0025037502 scopus 로고
    • GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase
    • Jackson SP, MacDonald JJ, Lees-Miller S, Tjian R. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase. Cell 1990;63:155-65.
    • (1990) Cell , vol.63 , pp. 155-165
    • Jackson, S.P.1    MacDonald, J.J.2    Lees-Miller, S.3    Tjian, R.4
  • 12
    • 0024280897 scopus 로고
    • O-glycosylation of eukaryotic transcription factors: Implications for mechanisms of transcriptional regulation
    • Jackson SP, Tjian R. O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation. Cell 1988;55:125-33.
    • (1988) Cell , vol.55 , pp. 125-133
    • Jackson, S.P.1    Tjian, R.2
  • 13
    • 33646838989 scopus 로고    scopus 로고
    • Sumoylation inhibits cleavage of Sp1 N-terminal negative regulatory domain and inhibits Sp1-dependent transcription
    • Spengler ML, Brattain MG. Sumoylation inhibits cleavage of Sp1 N-terminal negative regulatory domain and inhibits Sp1-dependent transcription. J Biol Chem 2006;281:5567-74.
    • (2006) J Biol Chem , vol.281 , pp. 5567-5574
    • Spengler, M.L.1    Brattain, M.G.2
  • 14
    • 0030973394 scopus 로고    scopus 로고
    • Casein kinase IImediated phosphorylation of the C terminus of Sp1 decreases its DNA binding activity
    • Armstrong SA, Barry DA, Leggett RW, Mueller CR. Casein kinase IImediated phosphorylation of the C terminus of Sp1 decreases its DNA binding activity. J Biol Chem 1997;272:13489-95.
    • (1997) J Biol Chem , vol.272 , pp. 13489-13495
    • Armstrong, S.A.1    Barry, D.A.2    Leggett, R.W.3    Mueller, C.R.4
  • 15
    • 0035887030 scopus 로고    scopus 로고
    • Fojas de Borja P, Collins NK, Du P, Azizkhan-Clifford J, Mudryj M. Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription. EMBO J 2001;20:5737-47.
    • Fojas de Borja P, Collins NK, Du P, Azizkhan-Clifford J, Mudryj M. Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription. EMBO J 2001;20:5737-47.
  • 16
    • 0037868957 scopus 로고    scopus 로고
    • Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons
    • Ryu H, Lee J, Zaman K, et al. Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons. J Neurosci 2003;23:3597-606.
    • (2003) J Neurosci , vol.23 , pp. 3597-3606
    • Ryu, H.1    Lee, J.2    Zaman, K.3
  • 17
    • 0034929708 scopus 로고    scopus 로고
    • Sp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancer
    • Black AR, Black JD, Azizkhan-Clifford J. Sp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancer. J Cell Physiol 2001;188:143-60.
    • (2001) J Cell Physiol , vol.188 , pp. 143-160
    • Black, A.R.1    Black, J.D.2    Azizkhan-Clifford, J.3
  • 19
    • 0033555521 scopus 로고    scopus 로고
    • Growth/cell cycle regulation of Sp1 phosphorylation
    • Black AR, Jensen D, Lin SY, Azizkhan JC. Growth/cell cycle regulation of Sp1 phosphorylation. J Biol Chem 1999;274:1207-15.
    • (1999) J Biol Chem , vol.274 , pp. 1207-1215
    • Black, A.R.1    Jensen, D.2    Lin, S.Y.3    Azizkhan, J.C.4
  • 20
    • 0036278167 scopus 로고    scopus 로고
    • Phosphorylation of transcription factor Sp1 during herpes simplex virus type 1 infection
    • Kim DB, DeLuca NA. Phosphorylation of transcription factor Sp1 during herpes simplex virus type 1 infection. J Virol 2002;76:6473-9.
    • (2002) J Virol , vol.76 , pp. 6473-6479
    • Kim, D.B.1    DeLuca, N.A.2
  • 21
    • 0032876617 scopus 로고    scopus 로고
    • Ionizing radiation stimulates octamer factor DNA binding activity in human carcinoma cells
    • Meighan-Mantha RL, Riegel AT, Suy S, et al. Ionizing radiation stimulates octamer factor DNA binding activity in human carcinoma cells. Mol Cell Biochem 1999;199:209-15.
    • (1999) Mol Cell Biochem , vol.199 , pp. 209-215
    • Meighan-Mantha, R.L.1    Riegel, A.T.2    Suy, S.3
  • 22
    • 0033973875 scopus 로고    scopus 로고
    • Coordinate modulation of Sp1, NF-κB, and p53 in confluent human malignant melanoma cells after ionizing radiation
    • Yang CR, Wilson-Van Patten C, Planchon SM, et al. Coordinate modulation of Sp1, NF-κB, and p53 in confluent human malignant melanoma cells after ionizing radiation. FASEB J 2000;14:379-90.
    • (2000) FASEB J , vol.14 , pp. 379-390
    • Yang, C.R.1    Wilson-Van Patten, C.2    Planchon, S.M.3
  • 23
    • 0037386621 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway
    • Ryu H, Lee J, Olofsson BA, et al. Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway. Proc Natl Acad Sci U S A 2003;100:4281-6.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 4281-4286
    • Ryu, H.1    Lee, J.2    Olofsson, B.A.3
  • 24
    • 4444339833 scopus 로고    scopus 로고
    • Oxidative DNA damage and disease: Induction, repair and significance
    • Evans MD, Dizdaroglu M, Cooke MS. Oxidative DNA damage and disease: induction, repair and significance. Mutat Res 2004;567:1-61.
    • (2004) Mutat Res , vol.567 , pp. 1-61
    • Evans, M.D.1    Dizdaroglu, M.2    Cooke, M.S.3
  • 26
    • 33745823159 scopus 로고    scopus 로고
    • The ATM-mediated DNA-damage response: Taking shape
    • Shiloh Y. The ATM-mediated DNA-damage response: taking shape. Trends Biochem Sci 2006;31:402-10.
    • (2006) Trends Biochem Sci , vol.31 , pp. 402-410
    • Shiloh, Y.1
  • 27
    • 3242882820 scopus 로고    scopus 로고
    • PI3-kinase related kinases: 'big' players in stress-induced signaling pathways
    • Abraham RT. PI3-kinase related kinases: 'big' players in stress-induced signaling pathways. DNA Repair (Amst) 2004;3:883-7.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 883-887
    • Abraham, R.T.1
  • 28
    • 0034798285 scopus 로고    scopus 로고
    • ATM: Genome stability, neuronal development, and cancer cross paths
    • Shiloh Y, Kastan MB. ATM: genome stability, neuronal development, and cancer cross paths. Adv Cancer Res 2001;83:209-54.
    • (2001) Adv Cancer Res , vol.83 , pp. 209-254
    • Shiloh, Y.1    Kastan, M.B.2
  • 30
    • 0033527717 scopus 로고    scopus 로고
    • Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
    • Cortez D, Wang Y, Qin J, Elledge SJ. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science 1999;286:1162-6.
    • (1999) Science , vol.286 , pp. 1162-1166
    • Cortez, D.1    Wang, Y.2    Qin, J.3    Elledge, S.J.4
  • 33
    • 0035878122 scopus 로고    scopus 로고
    • Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation
    • Lin WC, Lin FT, Nevins JR. Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev 2001;15:1833-44.
    • (2001) Genes Dev , vol.15 , pp. 1833-1844
    • Lin, W.C.1    Lin, F.T.2    Nevins, J.R.3
  • 34
    • 33644538632 scopus 로고    scopus 로고
    • Molecular linkage between the kinase ATM and NF-κB signaling in response to genotoxic stimuli
    • Wu ZH, Shi Y, Tibbetts RS, Miyamoto S. Molecular linkage between the kinase ATM and NF-κB signaling in response to genotoxic stimuli. Science 2006;311:1141-6.
    • (2006) Science , vol.311 , pp. 1141-1146
    • Wu, Z.H.1    Shi, Y.2    Tibbetts, R.S.3    Miyamoto, S.4
  • 35
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 1999;146:905-16.
    • (1999) J Cell Biol , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 36
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998;273:5858-68.
    • (1998) J Biol Chem , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 37
    • 0043009733 scopus 로고    scopus 로고
    • ATM-dependent and -independent gene expression changes in response to oxidative stress, γ irradiation, and UV irradiation
    • Heinloth AN, Shackelford RE, Innes CL, et al. ATM-dependent and -independent gene expression changes in response to oxidative stress, γ irradiation, and UV irradiation. Radiat Res 2003;160:273-90.
    • (2003) Radiat Res , vol.160 , pp. 273-290
    • Heinloth, A.N.1    Shackelford, R.E.2    Innes, C.L.3
  • 38
    • 9444297972 scopus 로고    scopus 로고
    • Ataxia-telangiectasia mutated gene controls insulin-like growth factor I receptor gene expression in a deoxyribonucleic acid damage response pathway via mechanisms involving zinc-finger transcription factors Sp1 and WT1
    • Shahrabani-Gargir L, Pandita TK, Werner H. Ataxia-telangiectasia mutated gene controls insulin-like growth factor I receptor gene expression in a deoxyribonucleic acid damage response pathway via mechanisms involving zinc-finger transcription factors Sp1 and WT1. Endocrinology 2004;145:5679-87.
    • (2004) Endocrinology , vol.145 , pp. 5679-5687
    • Shahrabani-Gargir, L.1    Pandita, T.K.2    Werner, H.3
  • 39
    • 17844372453 scopus 로고    scopus 로고
    • SQ/TQ cluster domains: Concentrated ATM/ATR kinase phosphorylation site regions in DNA-damage-response proteins
    • Traven A, Heierhorst J. SQ/TQ cluster domains: concentrated ATM/ATR kinase phosphorylation site regions in DNA-damage-response proteins. Bioessays 2005;27:397-407.
    • (2005) Bioessays , vol.27 , pp. 397-407
    • Traven, A.1    Heierhorst, J.2
  • 40
    • 0033621392 scopus 로고    scopus 로고
    • Substrate specificities and identification of putative substrates of ATM kinase family members
    • Kim ST, Lim DS, Canman CE, Kastan MB. Substrate specificities and identification of putative substrates of ATM kinase family members. J Biol Chem 1999;274:37538-43.
    • (1999) J Biol Chem , vol.274 , pp. 37538-37543
    • Kim, S.T.1    Lim, D.S.2    Canman, C.E.3    Kastan, M.B.4
  • 41
    • 0034725592 scopus 로고    scopus 로고
    • Utilization of oriented peptide libraries to identify substrate motifs selected by ATM
    • O'Neill T, Dwyer AJ, Ziv Y, et al. Utilization of oriented peptide libraries to identify substrate motifs selected by ATM. J Biol Chem 2000;275:22719-27.
    • (2000) J Biol Chem , vol.275 , pp. 22719-22727
    • O'Neill, T.1    Dwyer, A.J.2    Ziv, Y.3
  • 42
    • 0024276524 scopus 로고
    • Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif
    • Courey AJ, Tjian R. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell 1988;55:887-98.
    • (1988) Cell , vol.55 , pp. 887-898
    • Courey, A.J.1    Tjian, R.2
  • 43
    • 0037884963 scopus 로고    scopus 로고
    • Evidence for a lack of DNA double-strand break repair in human cells exposed to very low X-ray doses
    • Rothkamm K, Lobrich M. Evidence for a lack of DNA double-strand break repair in human cells exposed to very low X-ray doses. Proc Natl Acad Sci U S A 2003;100:5057-62.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 5057-5062
    • Rothkamm, K.1    Lobrich, M.2
  • 44
    • 0036789173 scopus 로고    scopus 로고
    • Quantitative detection of (125)IdU-induced DNA double-strand breaks with γ-H2AX antibody
    • Sedelnikova OA, Rogakou EP, Panyutin IG, Bonner WM. Quantitative detection of (125)IdU-induced DNA double-strand breaks with γ-H2AX antibody. Radiat Res 2002;158:486-92.
    • (2002) Radiat Res , vol.158 , pp. 486-492
    • Sedelnikova, O.A.1    Rogakou, E.P.2    Panyutin, I.G.3    Bonner, W.M.4
  • 45
    • 0033555260 scopus 로고    scopus 로고
    • A role for ATR in the DNA damage-induced phosphorylation of p53
    • Tibbetts RS, Brumbaugh KM, Williams JM, et al. A role for ATR in the DNA damage-induced phosphorylation of p53. Genes Dev 1999;13:152-7.
    • (1999) Genes Dev , vol.13 , pp. 152-157
    • Tibbetts, R.S.1    Brumbaugh, K.M.2    Williams, J.M.3
  • 46
    • 9744271049 scopus 로고    scopus 로고
    • Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
    • Hickson I, Zhao Y, Richardson CJ, et al. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res 2004;64:9152-9.
    • (2004) Cancer Res , vol.64 , pp. 9152-9159
    • Hickson, I.1    Zhao, Y.2    Richardson, C.J.3
  • 47
    • 15744393419 scopus 로고    scopus 로고
    • Chu S, Ferro TJ. Sp1: Regulation of gene expression by phosphorylation. Gene 2005;348:1-11.
    • Chu S, Ferro TJ. Sp1: Regulation of gene expression by phosphorylation. Gene 2005;348:1-11.
  • 48
    • 0032991791 scopus 로고    scopus 로고
    • CpG islands in chromatin organization and gene expression
    • Kundu TK, Rao MR. CpG islands in chromatin organization and gene expression. J Biochem (Tokyo) 1999;125:217-22.
    • (1999) J Biochem (Tokyo) , vol.125 , pp. 217-222
    • Kundu, T.K.1    Rao, M.R.2
  • 50
    • 0033855389 scopus 로고    scopus 로고
    • Mechanisms of DNA double-strand break repair and their potential to induce chromosomal aberrations
    • Pfeiffer P, Goedecke W, Obe G. Mechanisms of DNA double-strand break repair and their potential to induce chromosomal aberrations. Mutagenesis 2000;15:289-302.
    • (2000) Mutagenesis , vol.15 , pp. 289-302
    • Pfeiffer, P.1    Goedecke, W.2    Obe, G.3
  • 52
    • 0037218919 scopus 로고    scopus 로고
    • Sp1- and Kruppel-like transcription factors
    • Kaczynski J, Cook T, Urrutia R. Sp1- and Kruppel-like transcription factors. Genome Biol 2003;4:206.
    • (2003) Genome Biol , vol.4 , pp. 206
    • Kaczynski, J.1    Cook, T.2    Urrutia, R.3
  • 54
    • 0032866999 scopus 로고    scopus 로고
    • The Sp-family of transcription factors
    • Suske G. The Sp-family of transcription factors. Gene 1999;238:291-300.
    • (1999) Gene , vol.238 , pp. 291-300
    • Suske, G.1
  • 55
    • 34247843008 scopus 로고    scopus 로고
    • DNA topoisomerase inhibitor, etoposide, enhances GC-box-dependent promoter activity via Sp1 phosphorylation
    • Niina I, Uchiumi T, Izumi H, et al. DNA topoisomerase inhibitor, etoposide, enhances GC-box-dependent promoter activity via Sp1 phosphorylation. Cancer Sci 2007;98:858-63.
    • (2007) Cancer Sci , vol.98 , pp. 858-863
    • Niina, I.1    Uchiumi, T.2    Izumi, H.3
  • 56
    • 34249947699 scopus 로고    scopus 로고
    • ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
    • Matsuoka S, Ballif BA, Smogorzewska A, et al. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 2007;316:1160-6.
    • (2007) Science , vol.316 , pp. 1160-1166
    • Matsuoka, S.1    Ballif, B.A.2    Smogorzewska, A.3
  • 57
    • 0033229933 scopus 로고    scopus 로고
    • ATM: A mediator of multiple responses to genotoxic stress
    • Rotman G, Shiloh Y. ATM: a mediator of multiple responses to genotoxic stress. Oncogene 1999;18:6135-44.
    • (1999) Oncogene , vol.18 , pp. 6135-6144
    • Rotman, G.1    Shiloh, Y.2
  • 58
    • 0016786321 scopus 로고
    • Ataxia telangiectasia: A human mutation with abnormal radiation sensitivity
    • Taylor AM, Harnden DG, Arlett CF, et al. Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity. Nature 1975;258:427-9.
    • (1975) Nature , vol.258 , pp. 427-429
    • Taylor, A.M.1    Harnden, D.G.2    Arlett, C.F.3
  • 59
    • 0038011619 scopus 로고    scopus 로고
    • Loss of ATM sensitises p53-deficient cells to topoisomerase poisons and antimetabolites
    • Fedier A, Schlamminger M, Schwarz VA, Haller U, Howell SB, Fink D. Loss of ATM sensitises p53-deficient cells to topoisomerase poisons and antimetabolites. Ann Oncol 2003;14:938-45.
    • (2003) Ann Oncol , vol.14 , pp. 938-945
    • Fedier, A.1    Schlamminger, M.2    Schwarz, V.A.3    Haller, U.4    Howell, S.B.5    Fink, D.6
  • 60
    • 0043130465 scopus 로고    scopus 로고
    • The effect of loss of Brca1 on the sensitivity to anticancer agents in p53-deficient cells
    • Fedier A, Steiner RA, Schwarz VA, Lenherr L, Haller U, Fink D. The effect of loss of Brca1 on the sensitivity to anticancer agents in p53-deficient cells. Int J Oncol 2003;22:1169-73.
    • (2003) Int J Oncol , vol.22 , pp. 1169-1173
    • Fedier, A.1    Steiner, R.A.2    Schwarz, V.A.3    Lenherr, L.4    Haller, U.5    Fink, D.6
  • 61
    • 4344627438 scopus 로고    scopus 로고
    • Basal, oxidative and alkylative DNA damage, DNA repair efficacy and mutagen sensitivity in breast cancer
    • Blasiak J, Arabski M, Krupa R, et al. Basal, oxidative and alkylative DNA damage, DNA repair efficacy and mutagen sensitivity in breast cancer. Mutat Res 2004;554:139-48.
    • (2004) Mutat Res , vol.554 , pp. 139-148
    • Blasiak, J.1    Arabski, M.2    Krupa, R.3
  • 62
    • 0037086702 scopus 로고    scopus 로고
    • Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair
    • Kang J, Bronson RT, Xu Y. Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair. EMBO J 2002;21:1447-55.
    • (2002) EMBO J , vol.21 , pp. 1447-1455
    • Kang, J.1    Bronson, R.T.2    Xu, Y.3
  • 63
    • 0141954010 scopus 로고    scopus 로고
    • BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis
    • Quinn JE, Kennedy RD, Mullan PB, et al. BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis. Cancer Res 2003;63:6221-8.
    • (2003) Cancer Res , vol.63 , pp. 6221-6228
    • Quinn, J.E.1    Kennedy, R.D.2    Mullan, P.B.3
  • 64
    • 14644435658 scopus 로고    scopus 로고
    • Brca1-deficient murine mammary epithelial cells have increased sensitivity to CDDP and MMS
    • Sgagias MK, Wagner KU, Hamik B, et al. Brca1-deficient murine mammary epithelial cells have increased sensitivity to CDDP and MMS. Cell Cycle 2004;3:1451-6.
    • (2004) Cell Cycle , vol.3 , pp. 1451-1456
    • Sgagias, M.K.1    Wagner, K.U.2    Hamik, B.3
  • 65
    • 0031466618 scopus 로고    scopus 로고
    • Ataxia-telangiectasia and the Nijmegen breakage syndrome: Related disorders but genes apart
    • Shiloh Y. Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart. Annu Rev Genet 1997;31:635-62.
    • (1997) Annu Rev Genet , vol.31 , pp. 635-662
    • Shiloh, Y.1
  • 66
    • 0033485758 scopus 로고    scopus 로고
    • Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells
    • Yamaguchi-Iwai Y, Sonoda E, Sasaki MS, et al. Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells. EMBO J 1999;18:6619-29.
    • (1999) EMBO J , vol.18 , pp. 6619-6629
    • Yamaguchi-Iwai, Y.1    Sonoda, E.2    Sasaki, M.S.3
  • 67
    • 23944482310 scopus 로고    scopus 로고
    • Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis
    • Elkon R, Rashi-Elkeles S, Lerenthal Y, et al. Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis. Genome Biol 2005;6:R43.
    • (2005) Genome Biol , vol.6
    • Elkon, R.1    Rashi-Elkeles, S.2    Lerenthal, Y.3
  • 68
    • 33644843626 scopus 로고    scopus 로고
    • Parallel induction of ATM-dependent pro- and antiapoptotic signals in response to ionizing radiation in murine lymphoid tissue
    • Rashi-Elkeles S, Elkon R, Weizman N, et al. Parallel induction of ATM-dependent pro- and antiapoptotic signals in response to ionizing radiation in murine lymphoid tissue. Oncogene 2006;25:1584-92.
    • (2006) Oncogene , vol.25 , pp. 1584-1592
    • Rashi-Elkeles, S.1    Elkon, R.2    Weizman, N.3
  • 69
    • 9144247813 scopus 로고    scopus 로고
    • Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses
    • Stankovic T, Hubank M, Cronin D, et al. Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses. Blood 2004;103:291-300.
    • (2004) Blood , vol.103 , pp. 291-300
    • Stankovic, T.1    Hubank, M.2    Cronin, D.3
  • 70
    • 0035852706 scopus 로고    scopus 로고
    • ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response
    • Peretz S, Jensen R, Baserga R, Glazer PM. ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response. Proc Natl Acad Sci U S A 2001;98:1676-81.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 1676-1681
    • Peretz, S.1    Jensen, R.2    Baserga, R.3    Glazer, P.M.4
  • 71
    • 28844436714 scopus 로고    scopus 로고
    • Ataxia- telangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo
    • Shi Y, Dodson GE, Shaikh S, Rundell K, Tibbetts RS. Ataxia- telangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo. J Biol Chem 2005;280:40195-200.
    • (2005) J Biol Chem , vol.280 , pp. 40195-40200
    • Shi, Y.1    Dodson, G.E.2    Shaikh, S.3    Rundell, K.4    Tibbetts, R.S.5
  • 72
    • 24044489232 scopus 로고    scopus 로고
    • Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection
    • Shirata N, Kudoh A, Daikoku T, et al. Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection. J Biol Chem 2005;280:30336-41.
    • (2005) J Biol Chem , vol.280 , pp. 30336-30341
    • Shirata, N.1    Kudoh, A.2    Daikoku, T.3
  • 73
    • 35348925406 scopus 로고    scopus 로고
    • Enhanced phosphorylation of transcription factor Sp1 in response to herpes simplex virus type 1 infection is dependent on the ataxia telangiectasia-mutated protein
    • Iwahori S, Shirata N, Kawaguchi Y, et al. Enhanced phosphorylation of transcription factor Sp1 in response to herpes simplex virus type 1 infection is dependent on the ataxia telangiectasia-mutated protein. J Virol 2007;81:9653-64.
    • (2007) J Virol , vol.81 , pp. 9653-9664
    • Iwahori, S.1    Shirata, N.2    Kawaguchi, Y.3
  • 74
    • 0034749425 scopus 로고    scopus 로고
    • DNA damage-dependent nuclear dynamics of the Mre11 complex
    • Mirzoeva OK, Petrini JH. DNA damage-dependent nuclear dynamics of the Mre11 complex. Mol Cell Biol 2001;21:281-8.
    • (2001) Mol Cell Biol , vol.21 , pp. 281-288
    • Mirzoeva, O.K.1    Petrini, J.H.2
  • 75
    • 0029092910 scopus 로고
    • Determination of radiation-induced DNA strand breaks in individual cells by non-radioactive labelling of 3′ OH ends
    • Kodym R, Horth E. Determination of radiation-induced DNA strand breaks in individual cells by non-radioactive labelling of 3′ OH ends. Int J Radiat Biol 1995;68:133-9.
    • (1995) Int J Radiat Biol , vol.68 , pp. 133-139
    • Kodym, R.1    Horth, E.2
  • 76
    • 0025995937 scopus 로고
    • Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism
    • Pascal E, Tjian R. Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism. Genes Dev 1991;5:1646-56.
    • (1991) Genes Dev , vol.5 , pp. 1646-1656
    • Pascal, E.1    Tjian, R.2


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