메뉴 건너뛰기




Volumn 125, Issue 2, 1999, Pages 217-222

CpG islands in chromatin organization and gene expression

Author keywords

Chromatin remodeling; DNA methylation; Histone acetylation and deacetylation; Spermiogenesis; Transition proteins

Indexed keywords

DNA; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE;

EID: 0032991791     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022276     Document Type: Review
Times cited : (77)

References (61)
  • 1
    • 0022540321 scopus 로고
    • CpG rich islands and the function of DNA methylation
    • Bird, A.P. (1986) CpG rich islands and the function of DNA methylation. Nature 321, 209-213
    • (1986) Nature , vol.321 , pp. 209-213
    • Bird, A.P.1
  • 2
    • 0023216891 scopus 로고
    • CpG islands in vertebrate genome
    • Gardiner-Garden, M. and Frommer, M. (1987) CpG islands in vertebrate genome. J. Mol. Biol. 196, 261-282
    • (1987) J. Mol. Biol. , vol.196 , pp. 261-282
    • Gardiner-Garden, M.1    Frommer, M.2
  • 3
    • 0029587471 scopus 로고
    • The human genome: Organization and evolutionary history
    • Bernardi, G. (1995) The human genome: organization and evolutionary history. Annu. Rev. Genet. 29, 445-476
    • (1995) Annu. Rev. Genet. , vol.29 , pp. 445-476
    • Bernardi, G.1
  • 4
    • 0026001046 scopus 로고
    • CpG islands: Features and distribution in the genomes of vertebrates
    • Aissani, B. and Bernardi, G. (1991) CpG islands: Features and distribution in the genomes of vertebrates. Gene 106, 173-183
    • (1991) Gene , vol.106 , pp. 173-183
    • Aissani, B.1    Bernardi, G.2
  • 5
    • 0025944851 scopus 로고
    • CpG islands, genes and isochores in the genomes of vertebrates
    • Aissani, B. and Bernardi, G. (1991) CpG islands, genes and isochores in the genomes of vertebrates. Gene 106, 185-195
    • (1991) Gene , vol.106 , pp. 185-195
    • Aissani, B.1    Bernardi, G.2
  • 6
    • 0027141519 scopus 로고
    • Number of CpG islands and genes in human and mouse
    • Antequera, F. and Bird, A. (1993) Number of CpG islands and genes in human and mouse. Proc. Natl. Acad. Sci. USA 90, 11995-11999
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11995-11999
    • Antequera, F.1    Bird, A.2
  • 7
    • 0023472826 scopus 로고
    • CpG islands as gene markers in the vertebrate nucleus
    • Bird, A. (1987) CpG islands as gene markers in the vertebrate nucleus. Trends Genet. 3, 342-347
    • (1987) Trends Genet. , vol.3 , pp. 342-347
    • Bird, A.1
  • 11
    • 0027317479 scopus 로고
    • Demethylation of somatic and testis specific histone H2A and H2B genes in F9 embryonic carcinoma cells
    • Choi, Y.-C. and Chae, C.-B. (1993) Demethylation of somatic and testis specific histone H2A and H2B genes in F9 embryonic carcinoma cells. Mol. Cell. Biol. 13, 5538-5548
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5538-5548
    • Choi, Y.-C.1    Chae, C.-B.2
  • 12
    • 0027960055 scopus 로고
    • Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of CpG island
    • Macleod, D., Charlton, J., Mullins, J., and Bird, A.P. (1994) Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of CpG island. Genes Dev. 8, 2282-2292
    • (1994) Genes Dev. , vol.8 , pp. 2282-2292
    • Macleod, D.1    Charlton, J.2    Mullins, J.3    Bird, A.P.4
  • 13
    • 0028301317 scopus 로고
    • The distribution of CpG islands in mammalian chromosomes
    • Craig, J.M. and Bickmore, W.A. (1994) The distribution of CpG islands in mammalian chromosomes. Nat. Genet. 1, 376-382
    • (1994) Nat. Genet. , vol.1 , pp. 376-382
    • Craig, J.M.1    Bickmore, W.A.2
  • 15
    • 0031569366 scopus 로고    scopus 로고
    • The chromosomal distribution of CpG islands in the mouse: Evidence for scrambling in the rodent
    • Cross, S.H., Lee, H., Clark, V.H., Craig, J.M., Bird, A.P., and Bickmore, W.A. (1997) The chromosomal distribution of CpG islands in the mouse: evidence for scrambling in the rodent. Genomics 40, 454-461
    • (1997) Genomics , vol.40 , pp. 454-461
    • Cross, S.H.1    Lee, H.2    Clark, V.H.3    Craig, J.M.4    Bird, A.P.5    Bickmore, W.A.6
  • 16
    • 0031469678 scopus 로고    scopus 로고
    • Genomic imprinting: A chromatin connection
    • Feil, R. and Kelsey, G. (1997) Genomic imprinting: a chromatin connection. Am. J. Hum. Genet. 61, 1213-1219
    • (1997) Am. J. Hum. Genet. , vol.61 , pp. 1213-1219
    • Feil, R.1    Kelsey, G.2
  • 17
    • 0030743612 scopus 로고    scopus 로고
    • DNA methylation and imprinting: Why bother?
    • Jaenisch, R. (1997) DNA methylation and imprinting: Why bother? Trends Genet. 13, 323-329
    • (1997) Trends Genet. , vol.13 , pp. 323-329
    • Jaenisch, R.1
  • 18
    • 0344353077 scopus 로고
    • Maternal specific methylation of the imprinted Igf2r locus identifies the expressed locus as carrying the imprinted signal
    • Stoger, R., Kubicka, P., Liu, C.G., Kafri, T., Razin, A., Cedar, H., and Barlow, D.P. (1993) Maternal specific methylation of the imprinted Igf2r locus identifies the expressed locus as carrying the imprinted signal. Nat. Genet. 9, 407-413
    • (1993) Nat. Genet. , vol.9 , pp. 407-413
    • Stoger, R.1    Kubicka, P.2    Liu, C.G.3    Kafri, T.4    Razin, A.5    Cedar, H.6    Barlow, D.P.7
  • 24
    • 0028097981 scopus 로고
    • High resolution methylation analysis of the human hypoxanthine phosphoribosyl transferase gene 5′-region on the active and inactive X-chromosome: Correlation with binding sites for transcription factors
    • Hornstra, K. and Yang, T.P. (1994) High resolution methylation analysis of the human hypoxanthine phosphoribosyl transferase gene 5′-region on the active and inactive X-chromosome: correlation with binding sites for transcription factors. Mol. Cell. Biol. 14, 1419-1430
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1419-1430
    • Hornstra, K.1    Yang, T.P.2
  • 25
    • 0027251502 scopus 로고
    • Proposed role for DNA methylation in Alu transcriptional repression and mutational inactivation
    • Liu, W.M. and Schmid, C.W. (1993) Proposed role for DNA methylation in Alu transcriptional repression and mutational inactivation. Nucleic Acids Res. 21, 1351-1359
    • (1993) Nucleic Acids Res. , vol.21 , pp. 1351-1359
    • Liu, W.M.1    Schmid, C.W.2
  • 26
    • 0024365892 scopus 로고
    • Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
    • Greger, V., Passarge, E., Hopping, W., Messmer, E., and Horsthemk, B. (1989) Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum. Genet. 83, 155-158
    • (1989) Hum. Genet. , vol.83 , pp. 155-158
    • Greger, V.1    Passarge, E.2    Hopping, W.3    Messmer, E.4    Horsthemk, B.5
  • 30
    • 0027936406 scopus 로고
    • Progressive increases in the methylation status and heterochromatinization of the MyoD CpG island during oncogenic transformation
    • Rideout III, W.M., Eversole-cire, P., Spruck III, C.H., Hustad, C.M., Coetze, G.A., Gonzales, F.A., and Jones, P.A. (1994) Progressive increases in the methylation status and heterochromatinization of the MyoD CpG island during oncogenic transformation. Mol. Cell. Biol. 14, 6143-6161
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6143-6161
    • Rideout W.M. III1    Eversole-Cire, P.2    Spruck C.H. III3    Hustad, C.M.4    Coetze, G.A.5    Gonzales, F.A.6    Jones, P.A.7
  • 31
    • 0031104930 scopus 로고    scopus 로고
    • DNA methylation directs a time dependent repression of transcription
    • Kass, S.U., Landsberger, N., and Wolffe, A.P. (1997) DNA methylation directs a time dependent repression of transcription. Curr. Biol. 7, 157-165
    • (1997) Curr. Biol. , vol.7 , pp. 157-165
    • Kass, S.U.1    Landsberger, N.2    Wolffe, A.P.3
  • 32
    • 0025816339 scopus 로고
    • Analysis of CpG methylation and genomic footprinting at the tyrosine aminotransferase gene: DNA methylation alone is not sufficient to prevent protein binding in vivo
    • Weih, F., Nitsch, D., Reik, A., Schutz, G., and Becker, P.B. (1991) Analysis of CpG methylation and genomic footprinting at the tyrosine aminotransferase gene: DNA methylation alone is not sufficient to prevent protein binding in vivo. EMBO J. 10, 2559-2567
    • (1991) EMBO J. , vol.10 , pp. 2559-2567
    • Weih, F.1    Nitsch, D.2    Reik, A.3    Schutz, G.4    Becker, P.B.5
  • 33
    • 0024673303 scopus 로고
    • CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGT-CA abolishes specific factor binding as well as transcriptional activation
    • Iguchi-Ariga, S.M.M. and Schaffner, W. (1989) CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGT-CA abolishes specific factor binding as well as transcriptional activation. Genes Dev. 3, 612-619
    • (1989) Genes Dev. , vol.3 , pp. 612-619
    • Iguchi-Ariga, S.M.M.1    Schaffner, W.2
  • 34
    • 0027535235 scopus 로고
    • Effect of DNA methylation on DNA binding proteins and gene expression
    • Tate, P.H. and Bird, A. (1993) Effect of DNA methylation on DNA binding proteins and gene expression. Curr. Opin. Genet. Dev. 3, 226-231
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 226-231
    • Tate, P.H.1    Bird, A.2
  • 35
    • 0026747761 scopus 로고
    • Purification, sequence and cellular localization of a novel protein that binds to methyl DNA
    • Lewis, J.D., Mechan, R.R., Henzel, W.J., Maurer-Fogy, P., Jeppensen, F., Klein, F., and Bird, A. (1992) Purification, sequence and cellular localization of a novel protein that binds to methyl DNA. Cell 69, 905-914
    • (1992) Cell , vol.69 , pp. 905-914
    • Lewis, J.D.1    Mechan, R.R.2    Henzel, W.J.3    Maurer-Fogy, P.4    Jeppensen, F.5    Klein, F.6    Bird, A.7
  • 36
    • 0030071685 scopus 로고    scopus 로고
    • The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse
    • Tate, P., Skarnes, W., and Bird, A. (1996) The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse. Nat. Genet. 12, 205-208
    • (1996) Nat. Genet. , vol.12 , pp. 205-208
    • Tate, P.1    Skarnes, W.2    Bird, A.3
  • 37
    • 0342437491 scopus 로고    scopus 로고
    • MeCP2 is a transcriptional repressor with abundant sites in genomic chromatin
    • Nan, X., Campoy, F.J., and Bird, A. (1997) MeCP2 is a transcriptional repressor with abundant sites in genomic chromatin. Cell 88, 471-481
    • (1997) Cell , vol.88 , pp. 471-481
    • Nan, X.1    Campoy, F.J.2    Bird, A.3
  • 38
    • 0030710153 scopus 로고    scopus 로고
    • How does DNA methylation repress transcription
    • Kass, S.U., Pruss, D., and Wolffe, A.P. (1997) How does DNA methylation repress transcription. Trends Genet. 13, 444-449
    • (1997) Trends Genet. , vol.13 , pp. 444-449
    • Kass, S.U.1    Pruss, D.2    Wolffe, A.P.3
  • 39
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-Cp9 binding protein MeCP2 involves a histone deacetylase complex
    • Nan, N., Ng, K.-N., Johnson, C.A., Laherty, C.D., Turner, E.M., Eisenman, C.N., Bird, A. (1998) Transcriptional repression by the methyl-Cp9 binding protein MeCP2 involves a histone deacetylase complex. Nature 393, 386-389
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, N.1    Ng, K.-N.2    Johnson, C.A.3    Laherty, C.D.4    Turner, E.M.5    Eisenman, C.N.6    Bird, A.7
  • 41
    • 0032574859 scopus 로고    scopus 로고
    • Methylation meets acetylation
    • Bestor, T.H. (1998) Methylation meets acetylation. Nature 393, 311-312
    • (1998) Nature , vol.393 , pp. 311-312
    • Bestor, T.H.1
  • 42
    • 0032030770 scopus 로고    scopus 로고
    • Histone acetylation and transcriptional regulatory mechanisms
    • Struhl, K. (1998) Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 12, 599-606
    • (1998) Genes Dev. , vol.12 , pp. 599-606
    • Struhl, K.1
  • 43
    • 0030916336 scopus 로고    scopus 로고
    • What's up and down with histone deacetylation and transcription?
    • Pazin, M.J. and Kadonaga, J.T. (1997) What's up and down with histone deacetylation and transcription? Cell 89, 325-328
    • (1997) Cell , vol.89 , pp. 325-328
    • Pazin, M.J.1    Kadonaga, J.T.2
  • 44
    • 0032031606 scopus 로고    scopus 로고
    • Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complex, are also required for transcriptional function in vivo
    • Wang, L., Lin, L., and Berger, L. (1998) Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complex, are also required for transcriptional function in vivo. Genes Dev. 12, 640-653
    • (1998) Genes Dev. , vol.12 , pp. 640-653
    • Wang, L.1    Lin, L.2    Berger, L.3
  • 45
    • 0032030906 scopus 로고    scopus 로고
    • Histone acetyltransferase activity of yeast Gcn5 is required for the activation of target genes in vivo
    • Kuo, M.H., Zhou, J., Jambeck, P., Churchill, M.E.A., and Allis, C.D. (1998) Histone acetyltransferase activity of yeast Gcn5 is required for the activation of target genes in vivo. Genes Dev. 12, 627-639
    • (1998) Genes Dev. , vol.12 , pp. 627-639
    • Kuo, M.H.1    Zhou, J.2    Jambeck, P.3    Churchill, M.E.A.4    Allis, C.D.5
  • 47
    • 1842411320 scopus 로고    scopus 로고
    • Crystal structure of the nucleosome core particle at 2.8 Å resolution
    • Luger, K., Mader, A.W., Richmond, R.K., Sargent, D.F., and Richmond, T.J. (1997) Crystal structure of the nucleosome core particle at 2.8 Å resolution. Nature 389, 251-260
    • (1997) Nature , vol.389 , pp. 251-260
    • Luger, K.1    Mader, A.W.2    Richmond, R.K.3    Sargent, D.F.4    Richmond, T.J.5
  • 48
    • 0345215754 scopus 로고
    • Specific protection of methylated CpGs in mammalian nuclei
    • Antequera, F., Macleod, D., and Bird, A. (1989) Specific protection of methylated CpGs in mammalian nuclei. Cell 44, 535-543
    • (1989) Cell , vol.44 , pp. 535-543
    • Antequera, F.1    Macleod, D.2    Bird, A.3
  • 49
    • 0344784963 scopus 로고
    • DNA methylation affects the formation of active chromatin
    • Keshet, I., Lieman-Hurwitz, J., and Cedar, H. (1986) DNA methylation affects the formation of active chromatin. Cell 58, 509-517
    • (1986) Cell , vol.58 , pp. 509-517
    • Keshet, I.1    Lieman-Hurwitz, J.2    Cedar, H.3
  • 50
    • 0030885648 scopus 로고    scopus 로고
    • Histone under acetylation is an ancient component of mammalian X chromosome inactivation
    • Wakefield, M.J., Keohane, A.M., Turner, B.M., and Graves, J.A.M. (1997) Histone under acetylation is an ancient component of mammalian X chromosome inactivation. Proc. Natl. Acad. Sci. USA 94, 9665-9668
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9665-9668
    • Wakefield, M.J.1    Keohane, A.M.2    Turner, B.M.3    Graves, J.A.M.4
  • 51
    • 0025006860 scopus 로고
    • High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines
    • Antequera, F., Boyles, J., and Bird, A. (1990) High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell 62, 503-514
    • (1990) Cell , vol.62 , pp. 503-514
    • Antequera, F.1    Boyles, J.2    Bird, A.3
  • 53
    • 0345215750 scopus 로고    scopus 로고
    • Role of nucleosome remodeling and histone acetylation in transcriptional activation of chromatin. Mechanism of transcription
    • in press
    • Mizuguchi, G., Vassile, A., Tsukiyama, T., Nakatani, Y., and Wu, C. (1998) Role of nucleosome remodeling and histone acetylation in transcriptional activation of chromatin. Mechanism of transcription. Cold Spring Harbor Symp. Quant. Biol. (in press)
    • (1998) Cold Spring Harbor Symp. Quant. Biol.
    • Mizuguchi, G.1    Vassile, A.2    Tsukiyama, T.3    Nakatani, Y.4    Wu, C.5
  • 55
    • 0026455182 scopus 로고
    • Purification and characterization of the rat spermatid basic nuclear protein, TP4
    • Unni, E. and Meistrich, M.L. (1992) Purification and characterization of the rat spermatid basic nuclear protein, TP4. J. Biol. Chem. 267, 25359-25363
    • (1992) J. Biol. Chem. , vol.267 , pp. 25359-25363
    • Unni, E.1    Meistrich, M.L.2
  • 56
    • 0026084453 scopus 로고
    • Vertebrate protamine genes and the histone-protamine replacement reaction
    • Olivia, R. and Dixon, G.H. (1991) Vertebrate protamine genes and the histone-protamine replacement reaction. Prog. Nucleic Acid. Res. Mol. Biol. 40, 25-94
    • (1991) Prog. Nucleic Acid. Res. Mol. Biol. , vol.40 , pp. 25-94
    • Olivia, R.1    Dixon, G.H.2
  • 57
    • 0025941440 scopus 로고
    • Mammalian spermatid specific protein TP2 is a zinc metalloprotein with two finger motif
    • Baskaran, R. and Rao, M.R.S. (1991) Mammalian spermatid specific protein TP2 is a zinc metalloprotein with two finger motif. Biochem. Biophys. Res. Commun. 179, 1491-1499
    • (1991) Biochem. Biophys. Res. Commun. , vol.179 , pp. 1491-1499
    • Baskaran, R.1    Rao, M.R.S.2
  • 58
    • 0027939655 scopus 로고
    • Characterization of the zinc metalloprotein nature of rat spermatidal protein TP2
    • Kundu, T.K. and Rao, M.R.S. (1994) Characterization of the zinc metalloprotein nature of rat spermatidal protein TP2. FEBS Lett. 351, 6-10
    • (1994) FEBS Lett. , vol.351 , pp. 6-10
    • Kundu, T.K.1    Rao, M.R.S.2
  • 59
    • 0028930196 scopus 로고
    • DNA condensation by the rat spermatidal protein TP2 shows GC rich sequence preference and is zinc dependent
    • Kundu, T.K. and Rao, M.R.S. (1995) DNA condensation by the rat spermatidal protein TP2 shows GC rich sequence preference and is zinc dependent. Biochemistry 34, 5143-5150
    • (1995) Biochemistry , vol.34 , pp. 5143-5150
    • Kundu, T.K.1    Rao, M.R.S.2
  • 60
    • 0000592678 scopus 로고    scopus 로고
    • Zinc dependent recognition of a human CpG island sequence by the mammalian spermatidal protein TP2
    • Kundu, T.K. and Rao, M.R.S. (1996) Zinc dependent recognition of a human CpG island sequence by the mammalian spermatidal protein TP2. Biochemistry 35, 15626-15636
    • (1996) Biochemistry , vol.35 , pp. 15626-15636
    • Kundu, T.K.1    Rao, M.R.S.2
  • 61
    • 0031138480 scopus 로고    scopus 로고
    • Genomic analysis of the mouse protamine 1, protamine 2, and transition protein 2 gene cluster reveals hypermethylation in expressing cells
    • Choi, Y.C., Aizawa, A., and Hecht, N.B. (1997) Genomic analysis of the mouse protamine 1, protamine 2, and transition protein 2 gene cluster reveals hypermethylation in expressing cells. Mamm. Genome 8, 317-323
    • (1997) Mamm. Genome , vol.8 , pp. 317-323
    • Choi, Y.C.1    Aizawa, A.2    Hecht, N.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.