SPD-3 is required for spindle alignment in Caenorhabditis elegans embryos and localizes to mitochondria

Genetics

Volumn 177, Issue 3, 2007, Pages 1609-1620

  Dinkelmann, Maria V ^a   Zhang, Haining ^a   Skop, Ahna R ^a   White, John G ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Laboratory of Molecular Biology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; GREEN FLUORESCENT PROTEIN; PROTEIN DERIVATIVE; SPD 3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAENORHABDITIS ELEGANS; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; FEMALE; GENETIC ANALYSIS; MALE; MITOCHONDRION; MITOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SPINDLE CELL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CLONING, MOLECULAR; DNA PRIMERS; DNA, HELMINTH; DYNEIN ATPASE; FEMALE; GENES, HELMINTH; GREEN FLUORESCENT PROTEINS; MALE; MEIOSIS; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOTIC SPINDLE APPARATUS; PHENOTYPE; RECOMBINANT PROTEINS; RNA INTERFERENCE;

CAENORHABDITIS ELEGANS;

EID: 37248999775     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.107.078386     Document Type: Article

References (58)

1. ABRAHAM, R. T., 2004 The ATM-related kinase, hSMG-1, bridges genome and RNA surveillance pathways. DNA Repair 3: 919-925.
2. ARMSTRONG, L. C., A. J. SAENZ and P. BORNSTEIN, 1999 Metaxin 1 interacts with metaxin 2, a novel related protein associated with the mammalian mitochondrial outer membrane. J. Cell Biochem. 74: 11-22.
3. BADRINATH, A. S., and J. G. WHITE, 2003 Contrasting patterns of mitochondrial redistribution in the early lineages of Caenorhabditis elegans and Acrobeloides sp. PS1146. Dev. Biol. 258: 70-75.
4. BLUMENTHAL, T., and K. S. GLEASON, 2003 Caenorhabditis elegans operons: form and function. Nat. Rev. Genet. 4: 112-120.
5. BRAECKMAN, B. P., K. HOUTHOOFD, A. DE VREESE and J. R. VANFLETEREN, 1999 Apparent uncoupling of energy production and consumption in long-lived Clk mutants of Caenorhabditis elegans. Curr. Biol. 9: 493-496.
6. BRENNER, S., 1974 The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
7. BRUMBAUGH, K. M., D. M. OTTERNESS, C. GEISEN, V. OLIVEIRA, J. BROGNARD et al., 2004 The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells. Mol. Cell 14: 585-598.
8. BURKHARDT, J. K., C. J. ECHEVERRI, T. NILSSON and R. B. VALLEE, 1997 Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J. Cell Biol. 139: 469-484.
9. CARMINATI, J. L., and T. STEARNS, 1997 Microtubules orient the mitotic spindle in yeast through dynein-dependent interactions with the cell cortex. J. Cell Biol. 138: 629-641.
10. CHEN, F., B. M. HERSH, B. CONRADT, Z. ZHOU, D. RIEMER et al., 2000 Translocation of C. elegans CED-4 to nuclear membranes during cell death. Science 287: 1485-1489.
11. COWAN, C. R., and A. A. HYMAN, 2004 Asymmetric cell division in C. elegans: cortical polarity and spindle positioning. Annu. Rev. Cell. Dev. Biol. 20: 427-453.
12. DILLIN, A., A. L. HSU, N. ARANTES- OLIVEIRA, J. LEHRER-GRAIWER, H. HSIN et al., 2002 Rates of behavior and aging specified by mitochondrial function during development. Science 298: 2398-2401.
13. DILLMAN, 3RD, J. F., and K. K. PFISTER, 1994 Differential phosphorylation in vivo of cytoplasmic dynein associated with anterogradely moving organelles. J. Cell Biol. 127: 1671-1681.
14. FENG, J., F. BUSSIERE and S. HEKIMI, 2001 Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans. Dev. Cell 1: 633-644.
15. FIRE, A., S. XU, M. K. MONTGOMERY, S. A. KOSTAS, S. E. DRIVER et al., 1998 Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811.
16. GOLDEN, A., 2000 Cytoplasmic flow and the establishment of polarity in C. elegans 1-cell embryos. Curr. Opin. Genet. Dev. 10: 414-420.
17. GOLDSTEIN, B., and S. N. HIRD, 1996 Specification of the anteroposterior axis in Caenorhabditis elegans. Development 122: 1467-1474.
18. GONCZY, P., S. PICHLER, M. KIRKHAM and A. A. HYMAN, 1999 Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo. J. Cell Biol. 147: 135-150.
19. GRIMSON, A., S. O'CONNOR, C. L. NEWMAN and P. ANDERSON, 2004 SMG-1 is a phosphatidylinositol kinase-related protein kinase required for nonsense-mediated mRNA decay in Caenorhabditis elegans. Mol. Cell. Biol. 24: 7483-7490.
20. HELFAND, B. T., A. MIKAMI, R. B. VALLEE and R. D. GOLDMAN, 2002 A requirement for cytoplasmic dynein and dynactin in intermediate filament network assembly and organization. J. Cell Biol. 157: 795-806.
21. HIRD, S. N., and J. G. WHITE, 1993 Cortical and cytoplasmic flow polarity in early embryonic cells of Caenorhabditis elegans. J. Cell Biol. 121: 1343-1355.
22. HODGKIN, J., A. PAPP, R. PULAK, V. AMBROS and P. ANDERSON, 1989 A new kind of informational suppression in the nematode Caenorhabditis elegans. Genetics 123: 301-313.
23. HYMAN, A. A., and J. G. WHITE, 1987 Determination of cell division axes in the early embryogenesis of Caenorhabditis elegans. J. Cell Biol. 105: 2123-2135.
24. JAKUBOWSKI, J., and K. KORNFELD, 1999 A local, high-density, single-nucleotide polymorphism map used to clone Caenorhabditis elegans cdf-1. Genetics 153: 743-752.
25. JONASSEN, T., M. PROFT, F. RANDEZ-GIL, J. R. SCHULTZ, B. N. MARBOIS et al., 1998 Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis. J. Biol. Chem. 273: 3351-3357.
26. KAMATH, R. S., A. G. FRASER, Y. DONG, G. POULIN, R. DURBIN et al., 2003 Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-237.
27. KENYON, C., J. CHANG, E. GENSCH, A. RUDNER and R. TABTIANG, 1993 A C. elegans mutant that lives twice as long as wild type. Nature 366: 461-464.
28. KIDD, T., R. ABU-SHUMAYS, A. KATZEN, J. C. SISSON, G. JIMENEZ et al., 2005 The epsilon-subunit of mitochondrial ATP synthase is required for normal spindle orientation during the Drosophila embryonic divisions. Genetics 170: 697-708.
29. KIMURA, K. D., H. A. TISSENBAUM, Y. LIU and G. RUVKUN, 1997 daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277: 942-946.
30. LAKOWSKI, B., and S. HEKIMI, 1996 Determination of life-span in Caenorhabditis elegans by four clock genes. Science 272: 1010-1013.
31. LIN, S. X., K. L. FERRO and C. A. COLLINS, 1994 Cytoplasmic dynein undergoes intracellular redistribution concomitant with phosphorylation of the heavy chain in response to serum starvation and okadaic acid. J. Cell Biol. 127: 1009-1019.
32. MANGO, S. E., 2001 Stop making nonSense: the C. elegans smg genes. Trends Genet. 17: 646-653.
33. MATTHEWS, L. R., P. CARTER, D. THIERRY- MIEG and K. KEMPHUES, 1998 ZYG-9, a Caenorhabditis elegans protein required for microtubule organization and function, is a component of meiotic and mitotic spindle poles. J. Cell Biol. 141: 1159-1168.
34. MCGRAIL, M., and T. S. HAYS, 1997 The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila. Development 124: 2409-2419.
35. MITROVICH, Q. M., and P. ANDERSON, 2005 mRNA surveillance of expressed pseudogenes in C. elegans. Curr. Biol. 15: 963-967.
36. MUNRO, E., J. NANCE and J. R. PRIESS, 2004 Cortical flows powered by asymmetrical contraction transport PAR proteins to establish and maintain anterior-posterior polarity in the early C. elegans embryo. Dev. Cell 7: 413-424.
37. O'CONNELL, C. B., and Y. L. WANG, 2000 Mammalian spindle orientation and position respond to changes in cell shape in a dynein-dependent fashion. Mol. Biol. Cell 11: 1765-1774.
38. O'CONNELL, K. F., C. M. LEYS and J. G. WHITE, 1998 A genetic screen for temperature-sensitive cell-division mutants of Caenorhabditis elegans. Genetics 149: 1303-1321.
39. PANG, K. M., T. ISHIDATE, K. NAKAMURA, M. SHIRAYAMA, C. TRZEPACZ et al., 2004 The minibrain kinase homolog, mbk-2, is required for spindle positioning and asymmetric cell division in early C. elegans embryos. Dev. Biol. 265: 127-139.
40. PFISTER, K. K., M. W. SALATA, J. F. DILLMAN, 3RD, K. T. VAUGHAN, R. B. VALLEE et al., 1996 Differential expression and phosphorylation of the 74-kDa intermediate chains of cytoplasmic dynein in cultured neurons and glia. J. Biol. Chem. 271: 1687-1694.
41. PRAITIS, V., E. CASEY, D. COLLAR and J. AUSTIN, 2001 Creation of low-copy integrated transgenic lines in Caenorhabditis elegans. Genetics 157: 1217-1226.
42. RAPPAPORT, R., 1986 Establishment of the mechanism of cytokinesis in animal cells. Int. Rev. Cytol. 105: 245-281.
43. SCHETTER, A., P. ASKJAER, F. PIANO, I. MATTAJ and K. KEMPHUES, 2006 Nucleoporins NPP-1, NPP-3, NPP-4, NPP-11 and NPP-13 are required for proper spindle orientation in C. elegans. Dev. Biol. 289: 360-371.
44. SCHMIDT, A., J. KUNZ and M. N. HALL, 1996 TOR2 is required for organization of the actin cytoskeleton in yeast. Proc. Natl. Acad. Sci. USA 93: 13780-13785.
45. SCHMIDT, D. J., D. J. ROSE, W. M. SAXTON and S. STROME, 2005 Functional analysis of cytoplasmic dynein heavy chain in Caenorhabditis elegans with fast-acting temperature-sensitive mutations. Mol. Biol. Cell 16: 1200-1212.
46. SCOTT, B. A., M. S. AVIDAN and C. M. CROWDER, 2002 Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2. Science 296: 2388-2391.
47. SHIROGUCHI, K., and Y. Y. TOYOSHIMA, 2001 Regulation of monomeric dynein activity by ATP and ADP concentrations. Cell Motil. Cytoskeleton 49: 189-199.
48. SKOP, A. R., and J. G. WHITE, 1998 The dynactin complex is required for cleavage plane specification in early Caenorhabditis elegans embryos. Curr. Biol. 8: 1110-1116.
49. SKOP, A. R., D. BERGMANN, W. A. MOHLER and J. G. WHITE, 2001 Completion of cytokinesis in C. elegans requires a brefeldin A-sensitive membrane accumulation at the cleavage furrow apex. Curr. Biol. 11: 735-746.
50. SONNICHSEN, B., L. B. KOSKI, A. WALSH, P. MARSCHALL, B. NEUMANN et al., 2005 Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434: 462-469.
51. TIMMONS, L., and A. FIRE, 1998 Specific interference by ingested dsRNA. Nature 395: 854.
52. TSOU, M. F., A. HAYASHI, L. R. DEB ELLA, G. MCGRATH and L. S. ROSE, 2002 LET-99 determines spindle position and is asymmetrically enriched in response to PAR polarity cues in C. elegans embryos. Development 129: 4469-4481.
53. VARADI, A., L. I. JOHNSON-CADWELL, V. CIRULLI, Y. YOON, V. J. ALLAN et al., 2004 Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1. J. Cell Sci. 117: 4389-4400.
54. WHITE, J., and S. STROME, 1996 Cleavage plane specification in C. elegans: how to divide the spoils. Cell 84: 195-198.
55. WOKOSIN, D. L., J. M. SQUIRRELL, K. W. ELICEIRI and J. G. WHITE, 2003 An optical workstation with concurrent, independent multiphoton imaging and experimental laser microbeam capabilities. Rev. Sci. Instrum. 74: 193-201.
56. YAFFE, M. P., N. STUURMAN and R. D. VALE, 2003 Mitochondrial positioning in fission yeast is driven by association with dynamic microtubules and mitotic spindle poles. Proc. Natl. Acad. Sci. USA 100: 11424-11428.
57. YOCHEM, J., T. GU and M. HAN, 1998 A new marker for mosaic analysis in Caenorhabditis elegans indicates a fusion between hyp6 and hyp7, two major components of the hypodermis. Genetics 149: 1323-1334.
58. YODER, J. H., and M. HAN, 2001 Cytoplasmic dynein light intermediate chain is required for discrete aspects of mitosis in Caenorhabditis elegans. Mol. Biol. Cell 12: 2921-2933.