ZYG-9, a Caenorhabditis elegans protein required for microtubule organization and function, is a component of meiotic and mitotic spindle poles

Journal of Cell Biology

Volumn 141, Issue 5, 1998, Pages 1159-1168

  Matthews, Lisa R ^a   Carter, Philip ^a   Thierry Mieg, Danielle ^b   Kemphues, Ken ^a  

^a Department of Population Medicine and Diagnostic Sciences   (United States)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MICROTUBULE ASSOCIATED PROTEIN; MUTANT PROTEIN; NOCODAZOLE;

ARTICLE; CAENORHABDITIS ELEGANS; CENTROMERE; CENTROSOME; CONTROLLED STUDY; GENE MUTATION; MEIOSIS; MICROTUBULE ASSEMBLY; MITOSIS SPINDLE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CLONING, MOLECULAR; HELMINTH PROTEINS; HUMANS; MEIOSIS; MICROTUBULES; MITOSIS; MITOTIC SPINDLE APPARATUS; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE HOMOLOGY, AMINO ACID;

CAENORHABDITIS ELEGANS; INVERTEBRATA;

EID: 0032101370     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.141.5.1159     Document Type: Article

References (46)

1. Albertson, D. 1984. Formation of the first cleavage spindle in nematode embryos. Dev. Biol. 101:61-72.
2. Altschul, S.F., W. Gish, W. Miller, E.W. Myers, and D.J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403-410.
3. Andersen, S.S.L., and E. Karsenti. 1997. XMAP310: A Xenopus rescue-promoting factor localized to the mitotic spindle. J. Cell Biol. 139:975-983.
4. Andersen, S.S., B, Buendia, J.E. Dominguez, A. Sawyer, and E. Karsenti. 1994. Effect on microtubule dynamics of XMAP230, a microtubule-associated protein present in Xenopus laevis eggs and dividing cells. J. Cell Biol. 127: 1289-1299.
5. Ausubel, F.M., R. Brent, R.E. Kingston, J.G. Seidman, J.A. Smith, and K. Struhl. 1995. Current Protocols in Molecular Biology. V.B. Chanda, editor. John Wiley & Sons, Inc, New York.
6. Charrasse, S., M. Mazel, S. Taviaux, P. Berta, T. Chow, and C. Larroque. 1995. Characterization of the cDNA and pattern of expression of a new gene over-expressed in human hepatomas and colonic tumors. Eur. J. Biochem. 234: 406-413.
7. Charrasse, S., M. Schroeder, C. Gauthier-Rouviere, F. Ango, L. Cassimeris, D.L. Gard, and C. Larroque. 1998. The TOGp protein is a new human microtubule associated protein homologous to the Xenopus XMAP215. J. Cell Sci. 111:1371-1383.
8. Clark-Maguire, S., and P.E. Mains. 1994a. mei-1, a gene required for meiotic spindle formation in Caenorhabditis elegans, is a member of a family of ATP-ases. Genetics. 136:533-546.
9. Clark-Maguire, S., and P.E. Mains. 1994b. Localization of the mei-1 gene product of Caenorhabditis elegans, a meiotic-specific spindle component. J. Cell Biol. 126:199-209.
10. Collins, J., E. Forbes, and P. Anderson. 1989. The Tc3 family of transposable genetic elements in Caenorhabditis elegans. Genetics. 121:47-55.
11. Doxsey, S.J., P. Stein, L. Evans, P.D. Calarco, and M. Kirschner. 1994. Pericentrin, a highly conserved centrosome protein involved in microtubule organization. Cell. 76:639-650.
12. Draper, B.W., C.C. Mello, B. Bowerman, J. Hardin, and J.R. Priess. 1996. MEX-3 is a KH domain protein that regulates blastomere identity in early C. elegans embryos. Cell. 87:205-216.
13. Durbin, R.M., and J.T. Thierry-Mieg. 1991. A C. elegans database (ACeDB). FTP://ncbi.nlm.nih.gov/repository/ACeDB.
14. Gard, D.L., and M.W. Kirschner. 1987. A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end. J. Cell Biol. 105:2203-2215.
15. Gard, D.L., B.J. Cha, and M.M. Schroeder. 1995. Confocal immunofluorescence microscopy of microtubules, microtubule-associated proteins, and microtubule-organizing centers during amphibian oogenesis and early development. Curr. Top. Dev. Biol. 31:383-431.
16. Guo, S., and K.J. Kemphues. 1995. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell. 8145:611-620.
17. Harlow, E., and D.P. Lane. 1988. Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. 726 pp.
18. Hunter, C.P., and C. Kenyon. 1996. Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos. Cell. 87:217-226.
19. Hyman, A.A., and E. Karsenti. 1996. Morphogenetic properties of microtubules and mitotic spindle assembly. Cell. 84:401-410.
20. Kemphues, K.J., N. Wolf, W.B. Wood, and D. Hirsh. 1986. Two loci required for cytoplasmic organization in early embryos of Caenorhabditis elegans. Dev. Biol. 113:449-460.
21. Kemphues, K.J., M. Kusch, and N. Wolf. 1988. Maternal-effect lethal mutations on linkage group II of Caenorhabditis elegans. Genetics. 120:977-986.
22. Li, Q., and H.C. Joshi. 1995. Gamma-tubulin is a minus end-specific microtubule-binding protein. J. Cell Biol. 131:207-214.
23. Lin, R., S. Thompson, and J.R. Priess. 1995. pop-1 encodes an HMG box protein required for the specification of a mesoderm precursor in early C. elegans embryos. Cell. 83:599-609.
24. Mains, P.E., I. Sulston, and W.B. Wood. 1990a. Dominant maternal-effect mutations causing embryonic lethality in Caenorhabditis elegans. Genetics. 125: 351-369.
25. Mains, P.E., K.J. Kemphues, S.A. Sprunger, I.A. Sulston, and W.B. Wood. 1990b. Mutations affecting the meiotic and mitotic divisions of the early Caenorhabditis elegans embryo. Genetics. 126:593-605.
26. McNall, F.J., and R.D. Vale. 1993. Identification of katanin, an ATPase that severs and disassembles stable microtubules. Cell. 75:419-429.
27. McNally, F.J., K. Okawa, A. Iwamatsu, and R.D. Vale. 1996. Katanin, the microtubule-severing ATPase, is concentrated at centrosomes. J. Cell Sci. 109: 561-567.
28. Mello, C.C., J.M. Kramer, D. Stinchcomb, and V. Ambros. 1991. Efficient gene transfer in C. elegans: Extrachromosomal maintenance and integration of transforming sequences. EMBO (Eur. Mol. Biol. Organ.) J. 10:3959-3970.
29. Mello, C.C., C. Schubert, B. Draper, W. Zhang, R. Lobel, and J.R. Priess. 1996. The PIE-1 protein and germline specification in C. elegans embryos. Nature. 382:710-712.
30. Dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites. Genes Dev. 9:1572-1585.
31. Dis1: regions implicated in regulated localization and microtubule interaction. Genes Cells. 1:633-644.
32. Ohkura, H., Y. Adachi, N. Kinoshita, O. Niwa, T. Toda, and M. Yanagida. 1988. Cold-sensitive and caffeine-supersensitive mutants of the Schizosaccharomyces pombe dis genes implicated in sister chromatid separation during mitosis. EMBO (Eur. Mol. Biol. Organ.) J. 7:1465-1473.
33. Okkema, P.G., and A. Fire. 1994. The Caenorhabditis elegans NK-2 class homeoprotein CEH-22 is involved in combinatorial activation of gene expression in pharyngeal muscle. Development (Camb.). 120:2175-2186.
34. Rocheleau, C.E., W.D. Downs, R. Lin, C. Wittmann, Y. Bei, Y.H. Cha, M. Ali, J.R. Priess, and C.C. Mello. 1997. Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos. Cell. 90:707-716.
35. Sanger, F., S. Nicklen, and A.R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA. 74:5463-5467.
36. Saunders, W., D. Hornack, V. Lengyel, and C. Deng. 1997. The Saccharomyces cerevisiae kinesin-related motor Kar3p acts at preanaphase spindle poles to limit the number and length of cytoplasmic microtubules. J. Cell Biol. 137: 417-431.
37. Stearns, T., L. Evans, and M. Kirschner. 1991. Gamma-tubulin is a highly conserved component of the centrosome. Cell. 65:825-836.
38. Stewart-Savage, J., and R.D. Grey. 1982. The temporal and spatial relationships between cortical contraction, sperm trail formation, and pronuclear migration in fertilized eggs of Xenopus laevis. Wilhelm Roux's Arch. Dev. Biol. 191:241-245.
39. Vale, R.D. 1991. Severing of stable microtubules by a mitotically activated protein in Xenopus egg extracts. Cell. 64:827-839.
40. Vasquez, R.J., D.L. Gard, and L. Cassimeris. 1994. XMAP from Xenopus eggs promotes rapid plus end assembly of microtubules and rapid microtubule polymer turnover. J. Cell Biol. 127:985-993.
41. Verde, F., M. Dogterom, E. Stelzer, E. Karsenti, and S. Leibler. 1992. Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts. J. Cell Biol. 118:1097-1108.
42. Wang, P.J., and T.C. Huffaker. 1997. Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body. J. Cell Biol. 139: 1271-1280.
43. Waterston, R., and J. Sulston. 1995. The genome of Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA. 92:10836-10840.
44. Williams, B.D., B. Schrank, C. Huynh, R. Shownkeen, and R.H. Waterston. 1992. A genetic mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites. Genetics. 131:609-624.
45. Wood, W.B., R. Hecht, S. Carr, R. Vanderslice, N. Wolf, and D. Hirsh. 1980. Parental effects and phenotypic characterization of mutations that affect early development in Caenorhabditis elegans. Dev Biol. 74:446-469.
46. Zheng, Y., M.L. Wong, B. Alberts, and T. Mitchison. 1995. Nucleation of microtubule assembly by a gamma-tubulin-containing ring complex. Nature. 378:578-583.