메뉴 건너뛰기




Volumn 48, Issue 10, 2005, Pages 2097-2107

Inhibition of adipose tissue lipolysis increases intramuscular lipid use in type 2 diabetic patients

Author keywords

Acipimox; IMCL; IMTG; Insulin sensitivity; Skeletal muscle

Indexed keywords

ACIPIMOX; CARBOHYDRATE; CARBON 13; FATTY ACID; GLUCOSE; GLYCOGEN; LIPID; TRIACYLGLYCEROL; URANIUM;

EID: 26244464870     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-005-1889-x     Document Type: Article
Times cited : (41)

References (51)
  • 1
    • 0030689043 scopus 로고    scopus 로고
    • Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding
    • Oakes ND, Cooney GJ, Camilleri S, Chisholm DJ, Kraegen EW (1997) Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding. Diabetes 46:1768-1774
    • (1997) Diabetes , vol.46 , pp. 1768-1774
    • Oakes, N.D.1    Cooney, G.J.2    Camilleri, S.3    Chisholm, D.J.4    Kraegen, E.W.5
  • 2
    • 0030784947 scopus 로고    scopus 로고
    • Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: Parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA
    • Oakes ND, Bell KS, Furler SM et al (1997) Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA. Diabetes 46:2022-2028
    • (1997) Diabetes , vol.46 , pp. 2022-2028
    • Oakes, N.D.1    Bell, K.S.2    Furler, S.M.3
  • 3
    • 0026087478 scopus 로고
    • Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid
    • Storlien LH, Jenkins AB, Chisholm DJ, Pascoe WS, Khouri S, Kraegen EW (1991) Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid. Diabetes 40:280-289
    • (1991) Diabetes , vol.40 , pp. 280-289
    • Storlien, L.H.1    Jenkins, A.B.2    Chisholm, D.J.3    Pascoe, W.S.4    Khouri, S.5    Kraegen, E.W.6
  • 4
    • 0030969532 scopus 로고    scopus 로고
    • Skeletal muscle triglyceride levels are inversely related to insulin action
    • Pan DA, Lillioja S, Kriketos AD et al (1997) Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes 46:983-988
    • (1997) Diabetes , vol.46 , pp. 983-988
    • Pan, D.A.1    Lillioja, S.2    Kriketos, A.D.3
  • 5
    • 0032764784 scopus 로고    scopus 로고
    • 13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents
    • 13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes 48:1600-1606
    • (1999) Diabetes , vol.48 , pp. 1600-1606
    • Perseghin, G.1    Scifo, P.2    De Cobelli, F.3
  • 6
    • 0032960890 scopus 로고    scopus 로고
    • Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects
    • Jacob S, Machann J, Rett K et al (1999) Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects. Diabetes 48:1113-1119
    • (1999) Diabetes , vol.48 , pp. 1113-1119
    • Jacob, S.1    Machann, J.2    Rett, K.3
  • 7
    • 0033536157 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance in humans
    • Shulman GI (1999) Cellular mechanisms of insulin resistance in humans. Am J Cardiol 84:3J-10J
    • (1999) Am J Cardiol , vol.84
    • Shulman, G.I.1
  • 8
    • 50549202600 scopus 로고
    • The glucose-fatty acid cycle: Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle PJ, Garland PB, Hales CN, Newsholme EA (1963) The glucose-fatty acid cycle: its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1:785-789
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 9
    • 0037184925 scopus 로고    scopus 로고
    • Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
    • Yu C, Chen Y, Cline GW et al (2002) Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem 277:50230-50236
    • (2002) J Biol Chem , vol.277 , pp. 50230-50236
    • Yu, C.1    Chen, Y.2    Cline, G.W.3
  • 10
    • 0029948212 scopus 로고    scopus 로고
    • Mechanism of free fatty acid-induced insulin resistance in humans
    • Roden M, Price TB, Perseghin G et al (1996) Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest 97:2859-2865
    • (1996) J Clin Invest , vol.97 , pp. 2859-2865
    • Roden, M.1    Price, T.B.2    Perseghin, G.3
  • 11
    • 0345086474 scopus 로고    scopus 로고
    • Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade
    • Griffin ME, Marcucci MJ, Cline GW et al (1999) Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. Diabetes 48:1270-1274
    • (1999) Diabetes , vol.48 , pp. 1270-1274
    • Griffin, M.E.1    Marcucci, M.J.2    Cline, G.W.3
  • 12
    • 0035405847 scopus 로고    scopus 로고
    • Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects
    • Boden G, Lebed B, Schatz M, Homko C, Lemieux S (2001) Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects. Diabetes 50:1612-1617
    • (2001) Diabetes , vol.50 , pp. 1612-1617
    • Boden, G.1    Lebed, B.2    Schatz, M.3    Homko, C.4    Lemieux, S.5
  • 13
    • 0033927667 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance
    • Shulman GI (2000) Cellular mechanisms of insulin resistance. J Clin Invest 106:171-176
    • (2000) J Clin Invest , vol.106 , pp. 171-176
    • Shulman, G.I.1
  • 14
    • 0346729968 scopus 로고    scopus 로고
    • Ceramide content is increased in skeletal muscle from obese insulin-resistant humans
    • Adams JM, Pratipanawatr T, Berria R et al (2004) Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. Diabetes 53:25-31
    • (2004) Diabetes , vol.53 , pp. 25-31
    • Adams, J.M.1    Pratipanawatr, T.2    Berria, R.3
  • 15
    • 0033834079 scopus 로고    scopus 로고
    • Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle
    • Ellis BA, Poynten A, Lowy AJ et al (2000) Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle. Am J Physiol 279:E554-E560
    • (2000) Am J Physiol , vol.279
    • Ellis, B.A.1    Poynten, A.2    Lowy, A.J.3
  • 16
    • 0036300538 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκB-α
    • Itani SI, Ruderman NB, Schmieder F, Boden G (2002) Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκB-α. Diabetes 51:2005-2011
    • (2002) Diabetes , vol.51 , pp. 2005-2011
    • Itani, S.I.1    Ruderman, N.B.2    Schmieder, F.3    Boden, G.4
  • 17
    • 0142070953 scopus 로고    scopus 로고
    • Lipid peroxidation in skeletal muscle of obese as compared to endurance-trained humans: A case of good vs. bad lipids?
    • Russell AP, Gastaldi G, Bobbioni-Harsch E et al (2003) Lipid peroxidation in skeletal muscle of obese as compared to endurance-trained humans: a case of good vs. bad lipids? FEBS Lett 551:104-106
    • (2003) FEBS Lett , vol.551 , pp. 104-106
    • Russell, A.P.1    Gastaldi, G.2    Bobbioni-Harsch, E.3
  • 18
    • 0036896836 scopus 로고    scopus 로고
    • Malonyl coenzyme a and the regulation of functional carnitine palmitoyl-transferase-1 activity and fat oxidation in human skeletal muscle
    • Rasmussen BB, Holmbäck UC, Volpi E, Morio-Liondore B, Paddon-Jones D, Wolfe RR (2002) Malonyl coenzyme A and the regulation of functional carnitine palmitoyl-transferase-1 activity and fat oxidation in human skeletal muscle. J Clin Invest 110:1687-1693
    • (2002) J Clin Invest , vol.110 , pp. 1687-1693
    • Rasmussen, B.B.1    Holmbäck, U.C.2    Volpi, E.3    Morio-Liondore, B.4    Paddon-Jones, D.5    Wolfe, R.R.6
  • 19
    • 0036895727 scopus 로고    scopus 로고
    • Fatty acid oxidation in human skeletal muscle
    • Jensen MD (2002) Fatty acid oxidation in human skeletal muscle. J Clin Invest 110:1607-1609
    • (2002) J Clin Invest , vol.110 , pp. 1607-1609
    • Jensen, M.D.1
  • 20
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • Kelley DE, He J, Menshikova EV, Ritov VB (2002) Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51:2944-2950
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 21
    • 0033054725 scopus 로고    scopus 로고
    • Effects of weight loss on regional fat distribution and insulin sensitivity in obesity
    • Goodpaster B, Kelley D, Wing R, Meier A, Thaete F (1999) Effects of weight loss on regional fat distribution and insulin sensitivity in obesity. Diabetes 48:839-847
    • (1999) Diabetes , vol.48 , pp. 839-847
    • Goodpaster, B.1    Kelley, D.2    Wing, R.3    Meier, A.4    Thaete, F.5
  • 22
    • 0038697895 scopus 로고    scopus 로고
    • Intramyocellular lipids: Anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity
    • Thamer C, Machann J, Bachmann O et al (2003) Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity. J Clin Endocrinol Metab 88:1785-1791
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1785-1791
    • Thamer, C.1    Machann, J.2    Bachmann, O.3
  • 23
    • 4143060180 scopus 로고    scopus 로고
    • Intramyocellular lipid content in type 2 diabetes patients compared to overweight sedentary men and highly trained endurance athletes
    • van Loon LJC, Koopman R, Manders R, van der Weegen W, van Kranenburg GP, Keizer HA (2004) Intramyocellular lipid content in type 2 diabetes patients compared to overweight sedentary men and highly trained endurance athletes. Am J Physiol 287:E558-E565
    • (2004) Am J Physiol , vol.287
    • Van Loon, L.J.C.1    Koopman, R.2    Manders, R.3    Van Der Weegen, W.4    Van Kranenburg, G.P.5    Keizer, H.A.6
  • 24
    • 4644347353 scopus 로고    scopus 로고
    • Use of intramuscular triacylglycerol as a substrate source during exercise in humans
    • van Loon LJC (2004) Use of intramuscular triacylglycerol as a substrate source during exercise in humans. J Appl Physiol 97:1170-1187
    • (2004) J Appl Physiol , vol.97 , pp. 1170-1187
    • Van Loon, L.J.C.1
  • 25
    • 0348133545 scopus 로고    scopus 로고
    • Intramyocellular lipids form an important substrate source during moderate intensity exercise in endurance-trained males in a fasted state
    • van Loon LJC, Koopman R, Stegen JH, Wagenmakers AJ, Keizer HA, Saris WH (2003) Intramyocellular lipids form an important substrate source during moderate intensity exercise in endurance-trained males in a fasted state. J Physiol 553:611-625
    • (2003) J Physiol , vol.553 , pp. 611-625
    • Van Loon, L.J.C.1    Koopman, R.2    Stegen, J.H.3    Wagenmakers, A.J.4    Keizer, H.A.5    Saris, W.H.6
  • 26
    • 0037096150 scopus 로고    scopus 로고
    • Intramuscular triacylglycerol, glycogen and acetyl group metabolism during 4 h of moderate exercise in man
    • Watt MJ, Heigenhauser GJ, Dyck DJ, Spriet LL (2002) Intramuscular triacylglycerol, glycogen and acetyl group metabolism during 4 h of moderate exercise in man. J Physiol 541:969-978
    • (2002) J Physiol , vol.541 , pp. 969-978
    • Watt, M.J.1    Heigenhauser, G.J.2    Dyck, D.J.3    Spriet, L.L.4
  • 27
    • 0027378025 scopus 로고
    • Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration
    • Romijn JA, Coyle EF, Sidossis LS et al (1993) Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration. Am J Physiol 265:E380-E391
    • (1993) Am J Physiol , vol.265
    • Romijn, J.A.1    Coyle, E.F.2    Sidossis, L.S.3
  • 28
    • 0029620412 scopus 로고
    • Relationship between fatty acid delivery and fatty acid oxidation during strenuous exercise
    • Romijn JA, Coyle EF, Sidossis LS, Zhang XJ, Wolfe RR (1995) Relationship between fatty acid delivery and fatty acid oxidation during strenuous exercise. J Appl Physiol 79:1939-1945
    • (1995) J Appl Physiol , vol.79 , pp. 1939-1945
    • Romijn, J.A.1    Coyle, E.F.2    Sidossis, L.S.3    Zhang, X.J.4    Wolfe, R.R.5
  • 29
    • 0024244339 scopus 로고
    • Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM
    • Reaven GM, Hollenbeck C, Jeng CY, Wu MS, Chen YD (1988) Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM. Diabetes 37:1020-1024
    • (1988) Diabetes , vol.37 , pp. 1020-1024
    • Reaven, G.M.1    Hollenbeck, C.2    Jeng, C.Y.3    Wu, M.S.4    Chen, Y.D.5
  • 30
    • 23944465387 scopus 로고    scopus 로고
    • Inhibition of lipolysis increases intramuscular lipid and glycogen use in vivo in humans
    • DOI 10.1152/ajpendo.00092.2005
    • van Loon LJC, Thomason-Hughes M, Constantin-Teodosiu D et al (2005) Inhibition of lipolysis increases intramuscular lipid and glycogen use in vivo in humans. Am J Physiol Endocrinol Metab DOI 10.1152/ajpendo.00092.2005
    • (2005) Am J Physiol Endocrinol Metab
    • Van Loon, L.J.C.1    Thomason-Hughes, M.2    Constantin-Teodosiu, D.3
  • 31
    • 3042786319 scopus 로고    scopus 로고
    • Reduced plasma FFA availability increases net triacylglycerol degradation, but not GPAT or HSL activity, in human skeletal muscle
    • Watt MJ, Holmes AG, Steinberg GR, Mesa JL, Kemp BE, Febbraio MA (2004) Reduced plasma FFA availability increases net triacylglycerol degradation, but not GPAT or HSL activity, in human skeletal muscle. Am J Physiol 287:E120-E127
    • (2004) Am J Physiol , vol.287
    • Watt, M.J.1    Holmes, A.G.2    Steinberg, G.R.3    Mesa, J.L.4    Kemp, B.E.5    Febbraio, M.A.6
  • 32
    • 0014314267 scopus 로고
    • Intramuscular energy sources in exercising normal and pancreatectomized dogs
    • Issekutz B Jr, Paul P (1968) Intramuscular energy sources in exercising normal and pancreatectomized dogs. Am J Physiol 215:197-204
    • (1968) Am J Physiol , vol.215 , pp. 197-204
    • Issekutz Jr., B.1    Paul, P.2
  • 33
    • 0017080160 scopus 로고
    • Glucagon and plasma catecholamines during beta-receptor blockade in exercising man
    • Galbo H, Holst JJ, Christensen NJ, Hilsted J (1976) Glucagon and plasma catecholamines during beta-receptor blockade in exercising man. J Appl Physiol 40:855-863
    • (1976) J Appl Physiol , vol.40 , pp. 855-863
    • Galbo, H.1    Holst, J.J.2    Christensen, N.J.3    Hilsted, J.4
  • 34
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
    • Alberti KG, Zimmet PZ (1998) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15:539-553
    • (1998) Diabet Med , vol.15 , pp. 539-553
    • Alberti, K.G.1    Zimmet, P.Z.2
  • 35
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 36
    • 77049310862 scopus 로고
    • The gross composition of the body
    • Siri WE (1956) The gross composition of the body. Adv Biol Med Physiol 4:238-280
    • (1956) Adv Biol Med Physiol , vol.4 , pp. 238-280
    • Siri, W.E.1
  • 38
    • 0026128307 scopus 로고
    • Table of nonprotein respiratory quotient: An update
    • Peronnet F, Massicotte D (1991) Table of nonprotein respiratory quotient: an update. Can J Sport Sci 16:23-29
    • (1991) Can J Sport Sci , vol.16 , pp. 23-29
    • Peronnet, F.1    Massicotte, D.2
  • 39
    • 0025194501 scopus 로고
    • 2 during the infusion of C-1- Vs C-2-labeled acetate: Implications for tracer studies of substrate oxidation
    • 2 during the infusion of C-1- vs C-2-labeled acetate: implications for tracer studies of substrate oxidation. Am J Clin Nutr 51:248-252
    • (1990) Am J Clin Nutr , vol.51 , pp. 248-252
    • Wolfe, R.R.1    Jahoor, F.2
  • 40
    • 0033104611 scopus 로고    scopus 로고
    • Glucose kinetics during prolonged exercise in highly trained human subjects: Effect of glucose ingestion
    • Jeukendrup AE, Raben A, Gijsen A et al (1999) Glucose kinetics during prolonged exercise in highly trained human subjects: effect of glucose ingestion. J Physiol 515:579-589
    • (1999) J Physiol , vol.515 , pp. 579-589
    • Jeukendrup, A.E.1    Raben, A.2    Gijsen, A.3
  • 41
    • 26244454644 scopus 로고    scopus 로고
    • Influence of prolonged endurance cycling and recovery diet on intramuscular triglyceride content in humans
    • van Loon LJC, Schrauwen-Hinderling VB, Koopman R et al (2003) Influence of prolonged endurance cycling and recovery diet on intramuscular triglyceride content in humans. Am J Physiol 553:611-625
    • (2003) Am J Physiol , vol.553 , pp. 611-625
    • Van Loon, L.J.C.1    Schrauwen-Hinderling, V.B.2    Koopman, R.3
  • 43
    • 0036785028 scopus 로고    scopus 로고
    • Intramuscular triacylglycerol utilization in human skeletal muscle during exercise: Is there a controversy?
    • Watt MJ, Heigenhauser GJ, Spriet LL (2002) Intramuscular triacylglycerol utilization in human skeletal muscle during exercise: is there a controversy? J Appl Physiol 93:1185-1195
    • (2002) J Appl Physiol , vol.93 , pp. 1185-1195
    • Watt, M.J.1    Heigenhauser, G.J.2    Spriet, L.L.3
  • 44
    • 8844255630 scopus 로고    scopus 로고
    • Free fatty acids in obesity and type 2 diabetes: Defining their role in the development of insulin resistance and beta-cell dysfunction
    • Boden G, Shulman GI (2002) Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction. Eur J Clin Invest 32(S3):14-23
    • (2002) Eur J Clin Invest , vol.32 , Issue.S3 , pp. 14-23
    • Boden, G.1    Shulman, G.I.2
  • 45
    • 0032954778 scopus 로고    scopus 로고
    • Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
    • Dresner A, Laurent D, Marcucci M et al (1999) Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J Clin Invest 103:253-259
    • (1999) J Clin Invest , vol.103 , pp. 253-259
    • Dresner, A.1    Laurent, D.2    Marcucci, M.3
  • 46
    • 0030811602 scopus 로고    scopus 로고
    • The insulin sensitizer, BRL 49653, reduces systemic fatty acid supply and utilization and tissue lipid availability in the rat
    • Oakes ND, Camilleri S, Furler SM, Chisholm DJ, Kraegen EW (1997) The insulin sensitizer, BRL 49653, reduces systemic fatty acid supply and utilization and tissue lipid availability in the rat. Metabolism 46:935-942
    • (1997) Metabolism , vol.46 , pp. 935-942
    • Oakes, N.D.1    Camilleri, S.2    Furler, S.M.3    Chisholm, D.J.4    Kraegen, E.W.5
  • 47
    • 0037352280 scopus 로고    scopus 로고
    • PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect
    • Tunaru S, Kero J, Schaub A et al (2003) PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect. Nat Med 9:352-355
    • (2003) Nat Med , vol.9 , pp. 352-355
    • Tunaru, S.1    Kero, J.2    Schaub, A.3
  • 49
    • 0029849462 scopus 로고    scopus 로고
    • Increased glucose transport, phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects
    • Perseghin G, Price TB, Petersen KF et al (1996) Increased glucose transport, phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects. N Engl J Med 335:1357-1362
    • (1996) N Engl J Med , vol.335 , pp. 1357-1362
    • Perseghin, G.1    Price, T.B.2    Petersen, K.F.3
  • 50
    • 0030718605 scopus 로고    scopus 로고
    • Insulin signaling in human skeletal muscle: Time course and effect of exercise
    • Wojtaszewski JF, Hansen BF, Kiens B, Richter EA (1997) Insulin signaling in human skeletal muscle: time course and effect of exercise. Diabetes 46:1775-1781
    • (1997) Diabetes , vol.46 , pp. 1775-1781
    • Wojtaszewski, J.F.1    Hansen, B.F.2    Kiens, B.3    Richter, E.A.4
  • 51
    • 0034006412 scopus 로고    scopus 로고
    • Insulin signaling and insulin sensitivity after exercise in human skeletal muscle
    • Wojtaszewski JF, Hansen BF, Gade et al (2000) Insulin signaling and insulin sensitivity after exercise in human skeletal muscle. Diabetes 49:325-331
    • (2000) Diabetes , vol.49 , pp. 325-331
    • Wojtaszewski, J.F.1    Hansen, B.F.2    Gade3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.