Learning the drug target-likeness of a protein

Proteomics

Volumn 7, Issue 23, 2007, Pages 4255-4263

  Xu, Huan ^a   Xu, HangYang ^a   Lin, MingZhi ^a   Wang, Wei ^a   Li, ZiMu ^a   Huang, JiaJu ^a   Chen, YuZong ^b   Chen, Xin ^a,c  

^a ZHEJIANG UNIVERSITY   (China)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Drug target; Drug target likeness; Protein features; Statistical learning; Support vector machine

Indexed keywords

ABATACEPT; ACETYLSALICYLIC ACID; ADALIMUMAB; ALEFACEPT; BALICATIB; BELATACEPT; CATHEPSIN K; CHLORTALIDONE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; EPTIFIBATIDE; ETANERCEPT; FOMIVIRSEN; HISTONE DEACETYLASE; IMMEDIATE EARLY PROTEIN; INFLIXIMAB; INOSINATE DEHYDROGENASE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; POTASSIUM CHLORIDE; RESVERATROL; SILDENAFIL; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; TUMOR NECROSIS FACTOR RECEPTOR 2; VORINOSTAT;

AMINO ACID SEQUENCE; ARTICLE; DRUG INDUSTRY; DRUG TARGETING; LEARNING ALGORITHM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; SINGLE NUCLEOTIDE POLYMORPHISM; SUPPORT VECTOR MACHINE; TISSUE SPECIFICITY;

ALGORITHMS; AMINO ACID SEQUENCE; ARTIFICIAL INTELLIGENCE; COMPUTATIONAL BIOLOGY; DATABASES, PROTEIN; GENE EXPRESSION; HUMANS; MODELS, STATISTICAL; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; PROTEINS; REPRODUCIBILITY OF RESULTS; ROC CURVE; VARIATION (GENETICS);

EID: 37049006774     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200700062     Document Type: Article

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