Site-specific insertion of 3-aminotyrosine into subunit α2 of E. coli ribonucleotide reductase: Direct evidence for involvement of Y730 and Y731 in radical propagation

Journal of the American Chemical Society

Volumn 129, Issue 48, 2007, Pages 15060-15071

  Seyedsayamdost, Mohammad R ^a   Xie, Jianming ^b   Chan, Clement T Y ^a   Schultz, Peter G ^b   Stubbe, Joanne ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3-AMINOTYROSINE; DEOXYNUCLEOTIDES; HYDROGEN ATOM TRANSFER MECHANISM;

BINDING SITES; ENZYME ACTIVITY; NUCLEOTIDES; PARAMAGNETIC RESONANCE; REDUCTION; SUBSTRATES; ULTRAVIOLET VISIBLE SPECTROSCOPY;

AMINO ACIDS;

3 AMINOTYROSINE; ADENOSINE TRIPHOSPHATE; AMINO ACID TRANSFER RNA LIGASE; RADICAL; RIBONUCLEOTIDE REDUCTASE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME ASSAY; ENZYME SUBUNIT; ESCHERICHIA COLI; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; RADICAL REACTION;

AMINATION; ELECTRONS; ESCHERICHIA COLI; FREE RADICALS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PROTEIN SUBUNITS; RIBONUCLEOTIDE REDUCTASES; TYROSINE;

EID: 36849004028     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja076043y     Document Type: Article

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