-
1
-
-
12944271053
-
Cancer statistics 2005
-
A. Jemal, T. Murray, E. Ward, A. Samuels, R.C. Tiwari, A. Ghafoor, E.J. Feuer and M.J. Thun, Cancer statistics, 2005, CA Cancer J Clin 55 (2005), 10-30.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 10-30
-
-
Jemal, A.1
Murray, T.2
Ward, E.3
Samuels, A.4
Tiwari, R.C.5
Ghafoor, A.6
Feuer, E.J.7
Thun, M.J.8
-
2
-
-
6944230093
-
Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging
-
J.B. O'Connell, M.A. Maggard and C.Y. Ko, Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging, J Natl Cancer Inst 96 (2004), 1420-1425.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1420-1425
-
-
O'Connell, J.B.1
Maggard, M.A.2
Ko, C.Y.3
-
3
-
-
0034642605
-
Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
-
R. Gryfe, H. Kim, E.T. Hsieh, M.D. Aronson, E.J. Holowaty, S.B. Bull, M. Redston and S. Gallinger, Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer, N Engl J Med 342 (2000), 69-77.
-
(2000)
N Engl J Med
, vol.342
, pp. 69-77
-
-
Gryfe, R.1
Kim, H.2
Hsieh, E.T.3
Aronson, M.D.4
Holowaty, E.J.5
Bull, S.B.6
Redston, M.7
Gallinger, S.8
-
4
-
-
14544300998
-
Systematic review of microsatellite instability and colorectal cancer prognosis
-
S. Popat, R. Hubner and R.S. Houlston, Systematic review of microsatellite instability and colorectal cancer prognosis, J Clin Oncol 23 (2005), 609-618.
-
(2005)
J Clin Oncol
, vol.23
, pp. 609-618
-
-
Popat, S.1
Hubner, R.2
Houlston, R.S.3
-
5
-
-
10744228074
-
Use of 5-fluorouracil and survival in patients with microsatellite- unstable colorectal cancer
-
J.M. Carethers, E.J. Smith, C.A. Behling, L. Nguyen, A. Tajima, R.T. Doctolero, B.L. Cabrera, A. Goel, C.A. Arnold, K. Miyai ANC C.R. Boland, Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer, Gastroenterology 126 (2004), 394-401.
-
(2004)
Gastroenterology
, vol.126
, pp. 394-401
-
-
Carethers, J.M.1
Smith, E.J.2
Behling, C.A.3
Nguyen, L.4
Tajima, A.5
Doctolero, R.T.6
Cabrera, B.L.7
Goel, A.8
Arnold, C.A.9
Miyai, K.10
Boland, A.N.C.C.R.11
-
6
-
-
0038002279
-
Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer
-
C.M. Ribic, D.J. Sargent, M.J. Moore, S.N. Thibodeau, A.J. French, R.M. Goldberg, S.R. Hamilton, P. Laurent-Puig, R. Gryfe, L.E. Shepherd, D. Tu, M. Redston and S. Gallinger, Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer, N Engl J Med 349 (2003), 247-257.
-
(2003)
N Engl J Med
, vol.349
, pp. 247-257
-
-
Ribic, C.M.1
Sargent, D.J.2
Moore, M.J.3
Thibodeau, S.N.4
French, A.J.5
Goldberg, R.M.6
Hamilton, S.R.7
Laurent-Puig, P.8
Gryfe, R.9
Shepherd, L.E.10
Tu, D.11
Redston, M.12
Gallinger, S.13
-
7
-
-
33646798052
-
Mismatch repair status in the prediction of benefit from adjuvant fluorouracil chemotherapy in colorectal cancer
-
in press
-
R. Jover, P. Zapater, A. Castells, X. Llor, M. Andreu, J. Cubiella, V. Pinol, R. Xicola, L. Bujanda, J.M. Rene, J. Clofent, X. Bessa, J.D. Morillas, D. Nicolas-Perez, A. Paya and C. Alenda, Mismatch repair status in the prediction of benefit from adjuvant fluorouracil chemotherapy in colorectal cancer, Gut (2006), (in press).
-
(2006)
Gut
-
-
Jover, R.1
Zapater, P.2
Castells, A.3
Llor, X.4
Andreu, M.5
Cubiella, J.6
Pinol, V.7
Xicola, R.8
Bujanda, L.9
Rene, J.M.10
Clofent, J.11
Bessa, X.12
Morillas, J.D.13
Nicolas-Perez, D.14
Paya, A.15
Alenda, C.16
-
8
-
-
0006262428
-
Diagnosis and management of primary and metastatic colorectal cancer
-
C.R. Boland, Diagnosis and management of primary and metastatic colorectal cancer, Seminars in Gastrointestinal Disease 3 (1992), 33-45.
-
(1992)
Seminars in Gastrointestinal Disease
, vol.3
, pp. 33-45
-
-
Boland, C.R.1
-
9
-
-
0033968125
-
Colorectal cancer prevention and treatment
-
C.R. Boland, F.A. Sinicrope, D.E. Brenner and J.M. Carethers, Colorectal cancer prevention and treatment, Gastroenterology 118 (2000), S115-S128.
-
(2000)
Gastroenterology
, vol.118
-
-
Boland, C.R.1
Sinicrope, F.A.2
Brenner, D.E.3
Carethers, J.M.4
-
10
-
-
0024397951
-
Surgical adjuvant therapy of large-bowel carcinoma: An evaluation of levamisole and the combination of levamisole and fluorouracil. The North Central Cancer Treatment Group and the Mayo Clinic
-
J.A. Laurie, C.G. Moertel, T.R. Fleming, H.S. Wieand, J.E. Leigh, J. Rubin, G.W. McCormack, J.B. Gerstner, J.E. Krook, J. Malliard et al., Surgical adjuvant therapy of large-bowel carcinoma: an evaluation of levamisole and the combination of levamisole and fluorouracil. The North Central Cancer Treatment Group and the Mayo Clinic, J Clin Oncol 7 (1989), 1447-1456.
-
(1989)
J Clin Oncol
, vol.7
, pp. 1447-1456
-
-
Laurie, J.A.1
Moertel, C.G.2
Fleming, T.R.3
Wieand, H.S.4
Leigh, J.E.5
Rubin, J.6
McCormack, G.W.7
Gerstner, J.B.8
Krook, J.E.9
Malliard, J.10
-
11
-
-
0025060806
-
Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma
-
C.G. Moertel, T.R. Fleming, J.S. Macdonald, D.G. Haller, J.A. Laurie, P.J. Goodman, J.S. Ungerleider, W.A. Emerson, D.C. Tormey, J.H. Glick et al., Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma, N Engl J Med 322 (1990), 352-358.
-
(1990)
N Engl J Med
, vol.322
, pp. 352-358
-
-
Moertel, C.G.1
Fleming, T.R.2
MacDonald, J.S.3
Haller, D.G.4
Laurie, J.A.5
Goodman, P.J.6
Ungerleider, J.S.7
Emerson, W.A.8
Tormey, D.C.9
Glick, J.H.10
-
12
-
-
0028956045
-
Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: A final report
-
C.G. Moertel, T.R. Fleming, J.S. Macdonald, D.G. Haller, J.A. Laurie, C.M. Tangen, J.S. Ungerleider, W.A. Emerson, D.C. Tormey, J.H. Glick, M.H. Veeder and J.A. Mailliard, Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report, Ann Intern Med 122 (1995), 321-326.
-
(1995)
Ann Intern Med
, vol.122
, pp. 321-326
-
-
Moertel, C.G.1
Fleming, T.R.2
MacDonald, J.S.3
Haller, D.G.4
Laurie, J.A.5
Tangen, C.M.6
Ungerleider, J.S.7
Emerson, W.A.8
Tormey, D.C.9
Glick, J.H.10
Veeder, M.H.11
Mailliard, J.A.12
-
13
-
-
21344457969
-
A phase I/II and pharmacokinetic study of irinotecan in combination with capecitabine as first-line therapy for advanced colorectal cancer
-
D.W. Rea, J.W. Nortier, W.W. Ten Bokkel Huinink, S. Falk, D.J. Richel, T. Maughan, G. Groenewegen, J.M. Smit, N. Steven, J.M. Bakker, D. Semiond, D.J. Kerr and C.J. Punt, A phase I/II and pharmacokinetic study of irinotecan in combination with capecitabine as first-line therapy for advanced colorectal cancer, Ann Oncol 16 (2005), 1123-1132.
-
(2005)
Ann Oncol
, vol.16
, pp. 1123-1132
-
-
Rea, D.W.1
Nortier, J.W.2
Ten Bokkel Huinink, W.W.3
Falk, S.4
Richel, D.J.5
Maughan, T.6
Groenewegen, G.7
Smit, J.M.8
Steven, N.9
Bakker, J.M.10
Semiond, D.11
Kerr, D.J.12
Punt, C.J.13
-
14
-
-
0344109583
-
Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advance colorectal cancer
-
Meta-analysis Group in Cancer
-
Meta-analysis Group in Cancer, Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advance colorectal cancer, J Clin Oncology 16 (1998), 301-308.
-
(1998)
J Clin Oncology
, vol.16
, pp. 301-308
-
-
-
15
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
J.G. Herman, A. Umar, K. Polyak, J.R. Graff, N. Ahuja, J.P. Issa, S. Markowitz, J.K. Willson, S.R. Hamilton, K.W. Kinzler, M.F. Kane, R.D. Kolodner, B. Vogelstein, T.A. Kunkel and S.B. Baylin, Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma, Proc Natl Acad Sci USA 95 (1998), 6870-6875.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
Graff, J.R.4
Ahuja, N.5
Issa, J.P.6
Markowitz, S.7
Willson, J.K.8
Hamilton, S.R.9
Kinzler, K.W.10
Kane, M.F.11
Kolodner, R.D.12
Vogelstein, B.13
Kunkel, T.A.14
Baylin, S.B.15
-
16
-
-
13144307115
-
Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
-
M.L. Veigl, L. Kasturi, J. Olechnowicz, A.H. Ma, J.D. Lutterbaugh, S. Periyasamy, G.M. Li, J. Drummond, P.L. Modrich, W.D. Sedwick and S.D. Markowitz, Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers, Proc Natl Acad Sci USA 95 (1998), 8698-8702.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8698-8702
-
-
Veigl, M.L.1
Kasturi, L.2
Olechnowicz, J.3
Ma, A.H.4
Lutterbaugh, J.D.5
Periyasamy, S.6
Li, G.M.7
Drummond, J.8
Modrich, P.L.9
Sedwick, W.D.10
Markowitz, S.D.11
-
17
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
E.R. Fearon and B. Vogelstein, A genetic model for colorectal tumorigenesis, Cell 61 (1990), 759.
-
(1990)
Cell
, vol.61
, pp. 759
-
-
Fearon, E.R.1
Vogelstein, B.2
-
18
-
-
0037379737
-
Characterization of sporadic colon cancer by patterns of genomic instability
-
A. Goel, C.N. Arnold, D. Niedzwiecki, D.K. Chang, L. Ricciardiello, J.M. Carethers, J.M. Dowell, L.Wasserman C. Compton, R.J. Mayer, M.M. Bertagnolli and C.R. Boland, Characterization of sporadic colon cancer by patterns of genomic instability, Cancer Res 63 (2003), 1608-1614.
-
(2003)
Cancer Res
, vol.63
, pp. 1608-1614
-
-
Goel, A.1
Arnold, C.N.2
Niedzwiecki, D.3
Chang, D.K.4
Ricciardiello, L.5
Carethers, J.M.6
Dowell, J.M.7
Wasserman, L.8
Compton, C.9
Mayer, R.J.10
Bertagnolli, M.M.11
Boland, C.R.12
-
19
-
-
0032534069
-
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
-
C.R. Boland, S.N. Thibodeau, S.R. Hamilton, D. Sidransky, J.R. Eshleman, R.W. Burt, S.J. Meltzer, M.A. Rodriguez-Bigas, R. Fodde, G.N. Ranzani and S. Srivastava, A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer, Cancer Res 58 (1998), 5248-5257.
-
(1998)
Cancer Res
, vol.58
, pp. 5248-5257
-
-
Boland, C.R.1
Thibodeau, S.N.2
Hamilton, S.R.3
Sidransky, D.4
Eshleman, J.R.5
Burt, R.W.6
Meltzer, S.J.7
Rodriguez-Bigas, M.A.8
Fodde, R.9
Ranzani, G.N.10
Srivastava, S.11
-
20
-
-
0012258405
-
One role for DNA methylation in vertebrate cells is strand discrimination in mismatch repair
-
J.T. Hare and J.H. Taylor, One role for DNA methylation in vertebrate cells is strand discrimination in mismatch repair, Proc Natl Acad Sci USA 82 (1985), 7350-7354.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 7350-7354
-
-
Hare, J.T.1
Taylor, J.H.2
-
21
-
-
0025777777
-
Heteroduplex repair in extracts of human HeLa cells
-
D.C. Thomas, J.D. Roberts and T.A. Kunkel, Heteroduplex repair in extracts of human HeLa cells, J Biol Chem 266 (1990), 3744-3751.
-
(1990)
J Biol Chem
, vol.266
, pp. 3744-3751
-
-
Thomas, D.C.1
Roberts, J.D.2
Kunkel, T.A.3
-
22
-
-
0030465237
-
HMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
-
S. Acharya, T. Wilson, S. Gradia, M.F. Kane, S. Guerrette, G.T. Marsischky, R. Kolodner and R. Fishel, hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6, Proc Natl Acad Sci USA 93 (1996), 13629-13634.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13629-13634
-
-
Acharya, S.1
Wilson, T.2
Gradia, S.3
Kane, M.F.4
Guerrette, S.5
Marsischky, G.T.6
Kolodner, R.7
Fishel, R.8
-
23
-
-
0032584384
-
Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha
-
J. Genschel, S.J. Littman, J.T. Drummond and P. Modrich, Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha, J Biol Chem 273 (1998), 19895-19901.
-
(1998)
J Biol Chem
, vol.273
, pp. 19895-19901
-
-
Genschel, J.1
Littman, S.J.2
Drummond, J.T.3
Modrich, P.4
-
24
-
-
0027145633
-
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
-
F.S. Leach, N.C. Nicolaides, N. Papadopoulos, B. Liu, J. Jen, R. Parsons, P. Peltomaki, P. Sistonen, L.A. Aaltonen, M. Nystrom-Lahti, X.-Y. Guan, J. Zhang, P.S. Meltzer, J.-W. Yu, F.-T. Kao, D.J. Chen, K.M. Cerosaletti, R.E.K. Fournier, S. Todd, T. Lewis, R.J. Leach, S.L. Naylor, J. Weissenbach, J.-P. Mecklin, H. Jarvinen, G.M. Petersen, S.R. Hamilton, J. Green, J. Jass, P. Watson, H.T. Lynch, J.M. Trent, A. de la Chapelle, K.W. Kinzler and B.Volgelstein, Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer, Cell 75 (1993), 1215-1225.
-
(1993)
Cell
, vol.75
, pp. 1215-1225
-
-
Leach, F.S.1
Nicolaides, N.C.2
Papadopoulos, N.3
Liu, B.4
Jen, J.5
Parsons, R.6
Peltomaki, P.7
Sistonen, P.8
Aaltonen, L.A.9
Nystrom-Lahti, M.10
Guan, X.-Y.11
Zhang, J.12
Meltzer, P.S.13
Yu, J.-W.14
Kao, F.-T.15
Chen, D.J.16
Cerosaletti, K.M.17
Fournier, R.E.K.18
Todd, S.19
Lewis, T.20
Leach, R.J.21
Naylor, S.L.22
Weissenbach, J.23
Mecklin, J.-P.24
Jarvinen, H.25
Petersen, G.M.26
Hamilton, S.R.27
Green, J.28
Jass, J.29
Watson, P.30
Lynch, H.T.31
Trent, J.M.32
De La Chapelle, A.33
Kinzler, K.W.34
Volgelstein, B.35
more..
-
25
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
R. Fishel, M.K. Lescoe, M.R.S. Rao, N.G. Copeland, N.A. Jenkins, J. Garber and M.R. Kane, The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer, Cell 75 (1993), 1027-1038.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.S.3
Copeland, N.G.4
Jenkins, N.A.5
Garber, J.6
Kane, M.R.7
-
26
-
-
0028350601
-
Mutation of a mutL homolog in hereditary colon cancer
-
N. Papadopoulos, N.C. Nicolaides, Y.-F. Wei, S.M. Ruben, K.C. Carter, C.A. Rosen, W.A. Haseltine, R.D. Fleischmann, C.M. Fraser, M.D. Adams, J.C. Venter, S.R. Hamilton, G.M. Petersen, P. Watson, H.T. Lynch, P. Peltomaki, J.-P. Mecklin, A. de la Chapelle, K.W. Kinzler and B. Volgelstein, Mutation of a mutL homolog in hereditary colon cancer, Science 263 (1994), 1625-1629.
-
(1994)
Science
, vol.263
, pp. 1625-1629
-
-
Papadopoulos, N.1
Nicolaides, N.C.2
Wei, Y.-F.3
Ruben, S.M.4
Carter, K.C.5
Rosen, C.A.6
Haseltine, W.A.7
Fleischmann, R.D.8
Fraser, C.M.9
Adams, M.D.10
Venter, J.C.11
Hamilton, S.R.12
Petersen, G.M.13
Watson, P.14
Lynch, H.T.15
Peltomaki, P.16
Mecklin, J.-P.17
De La Chapelle, A.18
Kinzler, K.W.19
Volgelstein, B.20
more..
-
27
-
-
0028221943
-
Mutation in the DNA mismatch repair homologue hMLH1 is associated with hereditary non-polyposis colon cancer
-
C.E. Bronner, S.M. Baker, P.T. Morrison, G. Warren, L.G. Smith, M.K. Lescoe, M. Kane, C. Earabino, J. Lipford, A. Lindblom, P. Tannergard, R.J. Bollag, A.R. Godwin, D.Ward, M. Nordenskjold, R. Fishel, R. Kolodner and R.M. Liskay, Mutation in the DNA mismatch repair homologue hMLH1 is associated with hereditary non-polyposis colon cancer, Nature 368 (1994), 258-261.
-
(1994)
Nature
, vol.368
, pp. 258-261
-
-
Bronner, C.E.1
Baker, S.M.2
Morrison, P.T.3
Warren, G.4
Smith, L.G.5
Lescoe, M.K.6
Kane, M.7
Earabino, C.8
Lipford, J.9
Lindblom, A.10
Tannergard, P.11
Bollag, R.J.12
Godwin, A.R.13
Ward, D.14
Nordenskjold, M.15
Fishel, R.16
Kolodner, R.17
Liskay, R.M.18
-
28
-
-
0030870631
-
Germ-line mutation of the hMSH6/GTBP gene in an atypical HNPCC kindred
-
Y. Akiyama, H. Sato andT.Yamada, Germ-line mutation of the hMSH6/GTBP gene in an atypical HNPCC kindred, Cancer Res 57 (1997), 3920-3923.
-
(1997)
Cancer Res
, vol.57
, pp. 3920-3923
-
-
Akiyama, Y.1
Sato, H.2
Yamada, T.3
-
29
-
-
0001628596
-
Familial endometrial cancer in female carriers of MSH6 germline mutations
-
J. Wijnen, W. de Leeuw, H. Vasen, H. van der Klift, P. Moller, A. Stormorken, H. Meijers-Heijboer, D. Lindhout, F. Menko, S. Vossen, G. Moslein, C. Tops, A. Brocker-Vriends, Y.Wu, R. Hofstra, R. Sijmons, C. Cornelisse, H. Morreau and R. Fodde, Familial endometrial cancer in female carriers of MSH6 germline mutations, Nature Genet 23 (1999), 142-144.
-
(1999)
Nature Genet
, vol.23
, pp. 142-144
-
-
Wijnen, J.1
De Leeuw, W.2
Vasen, H.3
Klift Der H.Van4
Moller, P.5
Stormorken, A.6
Meijers-Heijboer, H.7
Lindhout, D.8
Menko, F.9
Vossen, S.10
Moslein, G.11
Tops, C.12
Brocker-Vriends, A.13
Wu, Y.14
Hofstra, R.15
Sijmons, R.16
Cornelisse, C.17
Morreau, H.18
Fodde, R.19
-
30
-
-
0032749569
-
Germline msh6 mutations in colorectal cancer families
-
R.D. Kolodner, J.D. Tytell, J. Schmeits, M.F. Kane, R. Das Gupta, J. Weger, S. Wahlberg, E.Z. Fox, D. Peel, A. Ziogas, J.E. Garber, S. Syngal, H. Anton-Culver and F.P. Li, Germline msh6 mutations in colorectal cancer families, Cancer Res 59 (1999), 5068-5074.
-
(1999)
Cancer Res
, vol.59
, pp. 5068-5074
-
-
Kolodner, R.D.1
Tytell, J.D.2
Schmeits, J.3
Kane, M.F.4
Das Gupta, R.5
Weger, J.6
Wahlberg, S.7
Fox, E.Z.8
Peel, D.9
Ziogas, A.10
Garber, J.E.11
Syngal, S.12
Anton-Culver, H.13
Li, F.P.14
-
31
-
-
0029007870
-
DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines
-
P. Branch, R. Hampson and P. Karran, DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines, Cancer Res 55 (1995), 2304-2309.
-
(1995)
Cancer Res
, vol.55
, pp. 2304-2309
-
-
Branch, P.1
Hampson, R.2
Karran, P.3
-
32
-
-
0029943449
-
Mismatch repair in replication fidelity, genetic recombination, and cancer biology
-
P. Modrich and R. Lahue, Mismatch repair in replication fidelity, genetic recombination, and cancer biology, Ann Rev Biochem 65 (1996), 101-133.
-
(1996)
Ann Rev Biochem
, vol.65
, pp. 101-133
-
-
Modrich, P.1
Lahue, R.2
-
33
-
-
0029066689
-
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
-
S. Markowitz, J. Wang, L. Myeroff, R. Parsons, L. Sun, J. Lutterbaugh, R.S. Fan, E. Zborowska, K.W. Kinzler, B. Vogelstein, M. Brattain and J.K.V. Willson, Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability, Science 268 (1995), 1336-1338.
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
Wang, J.2
Myeroff, L.3
Parsons, R.4
Sun, L.5
Lutterbaugh, J.6
Fan, R.S.7
Zborowska, E.8
Kinzler, K.W.9
Vogelstein, B.10
Brattain, M.11
Willson, J.K.V.12
-
34
-
-
0029741089
-
Frameshift mutator mutations
-
S. Malkhosyan, N. Rampino, H. Yamamoto and M. Perucho, Frameshift mutator mutations, Nature 382 (1996), 499-500.
-
(1996)
Nature
, vol.382
, pp. 499-500
-
-
Malkhosyan, S.1
Rampino, N.2
Yamamoto, H.3
Perucho, M.4
-
35
-
-
0035881961
-
Instabilotyping: Comprehensive identification of frameshift mutations caused by coding region microsatellite instability
-
Y. Mori, J. Yin, A. Rashid, B.A. Leggett, J. Young, L. Simms, P.M. Kuehl, P. Langenberg, S.J. Meltzer and O.C. Stine, Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability, Cancer Res 61 (2001), 6046-6049.
-
(2001)
Cancer Res
, vol.61
, pp. 6046-6049
-
-
Mori, Y.1
Yin, J.2
Rashid, A.3
Leggett, B.A.4
Young, J.5
Simms, L.6
Kuehl, P.M.7
Langenberg, P.8
Meltzer, S.J.9
Stine, O.C.10
-
36
-
-
0031018674
-
Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
-
N. Rampino, H. Yamamoto, Y. Ionov, Y. Li, H. Sawai, J.C. Reed and M. Perucho, Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype, Science 75 (1997), 967-969.
-
(1997)
Science
, vol.75
, pp. 967-969
-
-
Rampino, N.1
Yamamoto, H.2
Ionov, Y.3
Li, Y.4
Sawai, H.5
Reed, J.C.6
Perucho, M.7
-
37
-
-
1542377485
-
Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers
-
B. Jung, R.T. Doctolero, A. Tajima, A.K. Nguyen, T. Keku, R.S. Sandler and J.M. Carethers, Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers, Gastroenterology 126 (2004), 654-659.
-
(2004)
Gastroenterology
, vol.126
, pp. 654-659
-
-
Jung, B.1
Doctolero, R.T.2
Tajima, A.3
Nguyen, A.K.4
Keku, T.5
Sandler, R.S.6
Carethers, J.M.7
-
38
-
-
0034108714
-
Mutations of transforming growth factor ?1 type II receptor, BAX, and insulin-like growth factor II receptor genes in microsatellite unstable cell lines
-
J.M. Carethers and T.-T.T. Pham, Mutations of transforming growth factor ?1 type II receptor, BAX, and insulin-like growth factor II receptor genes in microsatellite unstable cell lines, In Vivo 14 (2000), 13-20.
-
(2000)
Vivo
, vol.14
, pp. 13-20
-
-
Carethers, J.M.1
Pham, T.-T.T.2
-
39
-
-
0032527902
-
Mutation of the type II transforming growth factor-beta receptor is coincident with the transformation of human colon adenomas to malignant carcinomas
-
W.M. Grady, A. Rajput, L. Myeroff, D.F. Liu, K. Kwon, J. Willis, and S. Markowitz, Mutation of the type II transforming growth factor-beta receptor is coincident with the transformation of human colon adenomas to malignant carcinomas, Cancer Res 58 (1998), 3101-3104.
-
(1998)
Cancer Res
, vol.58
, pp. 3101-3104
-
-
Grady, W.M.1
Rajput, A.2
Myeroff, L.3
Liu, D.F.4
Kwon, K.5
Willis, J.6
Markowitz, S.7
-
40
-
-
33646391241
-
Influence of target gene mutation on survival, stage, and histology in sporadic microsatellite unstable colon cancers
-
in press
-
B. Jung, E.J. Smith, R.T. Doctolero, P. Gervaz, J.C. Alonso, T. Keku, R.S. Sandler and J.M. Carethers, Influence of target gene mutation on survival, stage, and histology in sporadic microsatellite unstable colon cancers, International Journal of Cancer (2006), (in press).
-
(2006)
International Journal of Cancer
-
-
Jung, B.1
Smith, E.J.2
Doctolero, R.T.3
Gervaz, P.4
Alonso, J.C.5
Keku, T.6
Sandler, R.S.7
Carethers, J.M.8
-
41
-
-
0027285475
-
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
-
Y. Ionov, M.A. Peinado, S. Malkhosyan et al., Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis, Nature 363 (1993), 558-561.
-
(1993)
Nature
, vol.363
, pp. 558-561
-
-
Ionov, Y.1
Peinado, M.A.2
Malkhosyan, S.3
-
42
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
S.N. Thibodeau, G. Bren and D. Schaid, Microsatellite instability in cancer of the proximal colon, Science 260 (1993), 816-819.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
43
-
-
0027158031
-
Clues to the pathogenesis of familial colorectal cancer
-
L.A. Aaltonen, P. Peltomaki, F.S. Leach, P. Sistonen, L. Pylkkanen, J.P. Mecklin, H. Jarvinen, S.M. Powell, J. Jen, S.R. Hamilton, G.M. Petersen, K.W. Kinzler, B. Vogelstein and A. de la Chapelle, Clues to the pathogenesis of familial colorectal cancer, Science 260 (1993), 812-816.
-
(1993)
Science
, vol.260
, pp. 812-816
-
-
Aaltonen, L.A.1
Peltomaki, P.2
Leach, F.S.3
Sistonen, P.4
Pylkkanen, L.5
Mecklin, J.P.6
Jarvinen, H.7
Powell, S.M.8
Jen, J.9
Hamilton, S.R.10
Petersen, G.M.11
Kinzler, K.W.12
Vogelstein, B.13
De La Chapelle, A.14
-
44
-
-
0035875903
-
Tumorinfiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinoma
-
T.C. Smyrk, P. Watson, K. Kaul and H.T. Lynch, Tumorinfiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinoma, Cancer 91 (2001), 2417-2422.
-
(2001)
Cancer
, vol.91
, pp. 2417-2422
-
-
Smyrk, T.C.1
Watson, P.2
Kaul, K.3
Lynch, H.T.4
-
45
-
-
0033953590
-
Genetic reconstruction of individual colorectal tumor histories
-
J.L. Tsao,Y.Yatabe, R. Salovaara et al., Genetic reconstruction of individual colorectal tumor histories, Proc Natl Acad Sci USA 97 (2000), 1236-1241.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1236-1241
-
-
Tsao, J.L.1
Yatabe, Y.2
Salovaara, R.3
-
46
-
-
5544242524
-
Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis
-
M. Guidoboni, R. Gafa, A. Viel, C. Doglioni, A. Russo, A. Santini, L. Del Tin, E. Macri, G. Lanza, M. Boiocchi and R. Dolcetti, Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis, Am J Pathol 159 (2001), 297-304.
-
(2001)
Am J Pathol
, vol.159
, pp. 297-304
-
-
Guidoboni, M.1
Gafa, R.2
Viel, A.3
Doglioni, C.4
Russo, A.5
Santini, A.6
Del Tin, L.7
MacRi, E.8
Lanza, G.9
Boiocchi, M.10
Dolcetti, R.11
-
47
-
-
0034852772
-
Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level
-
W.S. Samowitz, K. Curtin, K.N. Ma, D. Schaffer, L.W. Coleman, M. Leppert and M.L. Slattery, Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level, Cancer Epidemiol Biomarkers Prev 10 (2001), 917-923.
-
(2001)
Cancer Epidemiol Biomarkers Prev
, vol.10
, pp. 917-923
-
-
Samowitz, W.S.1
Curtin, K.2
Ma, K.N.3
Schaffer, D.4
Coleman, L.W.5
Leppert, M.6
Slattery, M.L.7
-
48
-
-
0028276912
-
Genetic steps in colorectal cancer
-
W. Bodmer, T. Bishop and P. Karran, Genetic steps in colorectal cancer, Nat Genet 6 (1994), 217-219.
-
(1994)
Nat Genet
, vol.6
, pp. 217-219
-
-
Bodmer, W.1
Bishop, T.2
Karran, P.3
-
49
-
-
0022515473
-
Lymphocytic infiltration and survival in rectal cancer
-
J.R. Jass, Lymphocytic infiltration and survival in rectal cancer, J Clin Pathol 39 (1986), 585-589.
-
(1986)
J Clin Pathol
, vol.39
, pp. 585-589
-
-
Jass, J.R.1
-
50
-
-
14944344603
-
The relationship between tumour T-lymphocyte infiltration, the systemic inflammatory response and survival in patients undergoing curative resection for colorectal cancer
-
K. Canna, P.A. McArdle, D.C. McMillan, A.M. McNicol, G.W. Smith, R.F. McKee and C.S. McArdle, The relationship between tumour T-lymphocyte infiltration, the systemic inflammatory response and survival in patients undergoing curative resection for colorectal cancer, Br J Cancer 92 (2005), 651-654.
-
(2005)
Br J Cancer
, vol.92
, pp. 651-654
-
-
Canna, K.1
McArdle, P.A.2
McMillan, D.C.3
McNicol, A.M.4
Smith, G.W.5
McKee, R.F.6
McArdle, C.S.7
-
51
-
-
0028362325
-
Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation
-
D. Shibata, M.A. Peinado, Y. Ionov, S. Malkhosyan and M. Perucho, Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation, Nat Genet 6 (1994), 273-281.
-
(1994)
Nat Genet
, vol.6
, pp. 273-281
-
-
Shibata, D.1
Peinado, M.A.2
Ionov, Y.3
Malkhosyan, S.4
Perucho, M.5
-
52
-
-
0033778049
-
Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy
-
A. Hemminki, J.P. Mecklin, H. Jarvinen, L.A. Aaltonen and H. Joensuu, Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy, Gastroenterology 119 (2000), 921-928.
-
(2000)
Gastroenterology
, vol.119
, pp. 921-928
-
-
Hemminki, A.1
Mecklin, J.P.2
Jarvinen, H.3
Aaltonen, L.A.4
Joensuu, H.5
-
53
-
-
0031891134
-
Prognostic significance of DNA replication errors in young patients with colorectal cancer
-
J.R. Lukish, K. Muro, J. DeNobile, R. Katz, J. Williams, D.F. Cruess, W. Drucker, I. Kirsch and S.R. Hamilton, Prognostic significance of DNA replication errors in young patients with colorectal cancer, Ann Surg 227 (1998), 51-56.
-
(1998)
Ann Surg
, vol.227
, pp. 51-56
-
-
Lukish, J.R.1
Muro, K.2
Denobile, J.3
Katz, R.4
Williams, J.5
Cruess, D.F.6
Drucker, W.7
Kirsch, I.8
Hamilton, S.R.9
-
54
-
-
0033986545
-
P53 gene mutation, microsatellite instability and adjuvant chemotherapy: Impact on survival of 388 patients with Dukes' C colon carcinoma
-
H. Elsaleh, B. Powell, P. Soontrapornchai, D. Joseph, F. Goria, N. Spry and B. Iacopetta, p53 gene mutation, microsatellite instability and adjuvant chemotherapy: impact on survival of 388 patients with Dukes' C colon carcinoma, Oncology 58 (2000), 52-59.
-
(2000)
Oncology
, vol.58
, pp. 52-59
-
-
Elsaleh, H.1
Powell, B.2
Soontrapornchai, P.3
Joseph, D.4
Goria, F.5
Spry, N.6
Iacopetta, B.7
-
55
-
-
0034690610
-
Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer
-
H. Elsaleh, D. Joseph, F. Grieu, N. Zeps, N. Spry and B. Iacopetta, Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer, Lancet 355 (2000), 1745-1750.
-
(2000)
Lancet
, vol.355
, pp. 1745-1750
-
-
Elsaleh, H.1
Joseph, D.2
Grieu, F.3
Zeps, N.4
Spry, N.5
Iacopetta, B.6
-
56
-
-
10744230297
-
Survival after adjuvant 5-FU treatment for stage III coon cancer in hereditary nonpolyposis colorectal cancer
-
W.H. de Vos tot Nedervee Cappel, H.J. Neulenbeld, J.H. Keibeuker, F.M. Nagengast, F.H. Menko, G. Griffioen, A. Cats, H. Morreau, H. Gelderblom and H.F. Vasen, Survival after adjuvant 5-FU treatment for stage III coon cancer in hereditary nonpolyposis colorectal cancer, In J Cancer 109 (2004), 468-471.
-
(2004)
J Cancer
, vol.109
, pp. 468-471
-
-
De Cappel, W.H.V.N.1
Neulenbeld, H.J.2
Keibeuker, J.H.3
Nagengast, F.M.4
Menko, F.H.5
Griffioen, G.6
Cats, A.7
Morreau, H.8
Gelderblom, H.9
Vasen, H.F.10
-
57
-
-
0030015770
-
Competency in mismatch repair prohibits clonal expansion of cancer cells treated with Nmethyl-N'-nitro-N-nitrosoguanidine
-
J.M. Carethers, M.T. Hawn, D.P. Chauhan, M.C. Luce, G. Marra, M. Koi and C.R. Boland, Competency in mismatch repair prohibits clonal expansion of cancer cells treated with Nmethyl-N'-nitro-N-nitrosoguanidine, J Clin Invest 98 (1996), 199-206.
-
(1996)
J Clin Invest
, vol.98
, pp. 199-206
-
-
Carethers, J.M.1
Hawn, M.T.2
Chauhan, D.P.3
Luce, M.C.4
Marra, G.5
Koi, M.6
Boland, C.R.7
-
58
-
-
0029143992
-
Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint
-
M.T. Hawn, A. Umar, J.M. Carethers, G. Marra, T.A. Kunkel, C.R. Boland and M. Koi, Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint, Cancer Res 55 (1995), 3721-3725.
-
(1995)
Cancer Res
, vol.55
, pp. 3721-3725
-
-
Hawn, M.T.1
Umar, A.2
Carethers, J.M.3
Marra, G.4
Kunkel, T.A.5
Boland, C.R.6
Koi, M.7
-
59
-
-
8944230189
-
Loss of DNA mismatch repair in acquired resistance to cisplatin
-
S. Aebi, B. Kurdi-Haidar, R. Gordon, B. Cenni, H. Zheng, D. Fink, R.D. Christen, C.R. Boland, M. Koi, R. Fishel and S.B. Howell, Loss of DNA mismatch repair in acquired resistance to cisplatin, Cancer Res 56 (1996), 3087-3090.
-
(1996)
Cancer Res
, vol.56
, pp. 3087-3090
-
-
Aebi, S.1
Kurdi-Haidar, B.2
Gordon, R.3
Cenni, B.4
Zheng, H.5
Fink, D.6
Christen, R.D.7
Boland, C.R.8
Koi, M.9
Fishel, R.10
Howell, S.B.11
-
60
-
-
0029904811
-
The role of DNA mismatch repair in platinum drug resistance
-
D. Fink, S. Nebel, S. Aebi, H. Zheng, B. Cenni, A. Nehme, R.D. Christen and S.B. Howell, The role of DNA mismatch repair in platinum drug resistance, Cancer Res 56 (1996), 4881-4886.
-
(1996)
Cancer Res
, vol.56
, pp. 4881-4886
-
-
Fink, D.1
Nebel, S.2
Aebi, S.3
Zheng, H.4
Cenni, B.5
Nehme, A.6
Christen, R.D.7
Howell, S.B.8
-
61
-
-
2442706833
-
Dependence of the cytotoxicity of DNA-damaging agents on the mismatch repair status of human cells
-
E. Papouli, P. Cejka and J. Jiricny, Dependence of the cytotoxicity of DNA-damaging agents on the mismatch repair status of human cells, Cancer Res 64 (2004), 3391-3394.
-
(2004)
Cancer Res
, vol.64
, pp. 3391-3394
-
-
Papouli, E.1
Cejka, P.2
Jiricny, J.3
-
62
-
-
0345357346
-
DNA mismatch repair and cancer
-
G.M. Li, DNA mismatch repair and cancer, Front Biosci 8 (2003), 997-1017.
-
(2003)
Front Biosci
, vol.8
, pp. 997-1017
-
-
Li, G.M.1
-
63
-
-
0036722801
-
Cellular effects of CPT-11 on colon carcinoma cells: Dependence on p53 and hMLH1 status
-
R. Magrini, M.R. Bhonde, M.L. Hanski, M. Notter, H. Scherubl, C.R. Boland, M. Zeitz and C. Hanski, Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status, Int J Cancer 101 (2002), 23-31.
-
(2002)
Int J Cancer
, vol.101
, pp. 23-31
-
-
Magrini, R.1
Bhonde, M.R.2
Hanski, M.L.3
Notter, M.4
Scherubl, H.5
Boland, C.R.6
Zeitz, M.7
Hanski, C.8
-
64
-
-
0035882531
-
Resistance to topoisomerase poisons due to loss of DNA mismatch repair
-
A. Fedier, V.A. Schwarz, H.Walt, R.D. Carpini, U. Haller and D. Fink, Resistance to topoisomerase poisons due to loss of DNA mismatch repair, Int J Cancer 93 (2001), 571-576.
-
(2001)
Int J Cancer
, vol.93
, pp. 571-576
-
-
Fedier, A.1
Schwarz, V.A.2
Walt, H.3
Carpini, R.D.4
Haller, U.5
Fink, D.6
-
65
-
-
0141731323
-
Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer
-
D. Fallik, F. Borrini, V. Boige, J. Viguier, S. Jacob, C. Miquel, J.C. Sabourin, M. Ducreaax and F. Praz, Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer, Cancer Res 63 (2003), 5738-5744.
-
(2003)
Cancer Res
, vol.63
, pp. 5738-5744
-
-
Fallik, D.1
Borrini, F.2
Boige, V.3
Viguier, J.4
Jacob, S.5
Miquel, C.6
Sabourin, J.C.7
Ducreaax, M.8
Praz, F.9
-
66
-
-
0025611018
-
Metabolism and mechanism of action of 5-fluorouracil
-
W.B. Parker and Y.C. Cheng, Metabolism and mechanism of action of 5-fluorouracil, Pharmacol Ther 48 (1990), 381-395.
-
(1990)
Pharmacol Ther
, vol.48
, pp. 381-395
-
-
Parker, W.B.1
Cheng, Y.C.2
-
67
-
-
0019947028
-
5-Fluorouracil incorporation in DNA of human breast carcinoma cells
-
P.P. Major, E. Egan, D. Herrick and D.W. Kufe, 5-Fluorouracil incorporation in DNA of human breast carcinoma cells, Cancer Res 42 (1982), 3005-3009.
-
(1982)
Cancer Res
, vol.42
, pp. 3005-3009
-
-
Major, P.P.1
Egan, E.2
Herrick, D.3
Kufe, D.W.4
-
68
-
-
0032993145
-
Mismatch repair proficiency and in vitro response to 5-fluorouracil
-
J.M. Carethers, D.P. Chauhan, D. Fink, S. Nebel, R.S. Bresalier, S.B. Howell and C.R. Boland, Mismatch repair proficiency and in vitro response to 5-fluorouracil, Gastroenterology 117 (1999), 123-131.
-
(1999)
Gastroenterology
, vol.117
, pp. 123-131
-
-
Carethers, J.M.1
Chauhan, D.P.2
Fink, D.3
Nebel, S.4
Bresalier, R.S.5
Howell, S.B.6
Boland, C.R.7
-
69
-
-
0019139737
-
The role of deoxyuridine triphosphate nucleotidohydrolase, uracil-DNA glycosylase, and DNA polymerase alpha in the metabolism of FUdR in human tumor cells
-
S.J. Caradonna and Y.C. Cheng, The role of deoxyuridine triphosphate nucleotidohydrolase, uracil-DNA glycosylase, and DNA polymerase alpha in the metabolism of FUdR in human tumor cells, Molec Pharmac 18 (1980), 513-520.
-
(1980)
Molec Pharmac
, vol.18
, pp. 513-520
-
-
Caradonna, S.J.1
Cheng, Y.C.2
-
70
-
-
0018875866
-
Mechanism for exclusion of 5-fluorouracil from DNA
-
H.A. Ingraham, B.Y. Tseng and M. Goulian, Mechanism for exclusion of 5-fluorouracil from DNA, Cancer Res 40 (1980), 998-1001.
-
(1980)
Cancer Res
, vol.40
, pp. 998-1001
-
-
Ingraham, H.A.1
Tseng, B.Y.2
Goulian, M.3
-
71
-
-
0022453878
-
DNA lesions in human neoplastic cells and cytotoxicity of 5-fluoropyrimidines
-
U. Lonn and S. Lonn, DNA lesions in human neoplastic cells and cytotoxicity of 5-fluoropyrimidines, Cancer Res 46 (1986), 3866-3870.
-
(1986)
Cancer Res
, vol.46
, pp. 3866-3870
-
-
Lonn, U.1
Lonn, S.2
-
72
-
-
0023154369
-
Dissociation of 5-fluorouracil-induced DNA fragmentation from either its incorporation into DNA or its cytotoxicity in murine T-lymphoma (S-49) cells
-
W.B. Parker, K.A. Kennedy and P. Klubes, Dissociation of 5-fluorouracil-induced DNA fragmentation from either its incorporation into DNA or its cytotoxicity in murine T-lymphoma (S-49) cells, Cancer Res 47 (1987), 979-982.
-
(1987)
Cancer Res
, vol.47
, pp. 979-982
-
-
Parker, W.B.1
Kennedy, K.A.2
Klubes, P.3
-
73
-
-
0019383730
-
Fluorinated pyrimidines as tight-binding inhibitors of thymidylate synthetase
-
P.V. Danenberg and A. Lockshin, Fluorinated pyrimidines as tight-binding inhibitors of thymidylate synthetase, Pharmac Ther 13 (1981), 69-90.
-
(1981)
Pharmac Ther
, vol.13
, pp. 69-90
-
-
Danenberg, P.V.1
Lockshin, A.2
-
74
-
-
0037869289
-
Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines
-
C.N. Arnold, A. Goel and C.R. Boland, Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines, Int J Cancer 106 (2003), 66-73.
-
(2003)
Int J Cancer
, vol.106
, pp. 66-73
-
-
Arnold, C.N.1
Goel, A.2
Boland, C.R.3
-
75
-
-
9644270289
-
The mismatch repair complex hMutS alpha recognizes 5-fluorouracil- modified DNA: Implications for chemosensitivity and resistance
-
A. Tajima, M.T. Hess, B.L. Cabrera, R.D. Kolodner and J.M. Carethers, The mismatch repair complex hMutS alpha recognizes 5-fluorouracil-modified DNA: implications for chemosensitivity and resistance, Gastroenterology 127 (2004), 1678-1684.
-
(2004)
Gastroenterology
, vol.127
, pp. 1678-1684
-
-
Tajima, A.1
Hess, M.T.2
Cabrera, B.L.3
Kolodner, R.D.4
Carethers, J.M.5
-
76
-
-
14044264185
-
DNA mismatch repair-dependent response to fluoropyrimidine-generated damage
-
M. Meyers, M.W. Wagner, A. Mazurek, C. Schmutte, R. Fishel and D.A. Boothman, DNA mismatch repair-dependent response to fluoropyrimidine-generated damage, J Biol Chem 280 (2005), 5516-5526.
-
(2005)
J Biol Chem
, vol.280
, pp. 5516-5526
-
-
Meyers, M.1
Wagner, M.W.2
Mazurek, A.3
Schmutte, C.4
Fishel, R.5
Boothman, D.A.6
-
77
-
-
2442670292
-
Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase
-
L. Stojic, N. Mojas, P. Cejka, M. Di Pietro, S. Ferrari, G. Marra and J. Jiricny, Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase, Genes Dev 18 (2004), 1331-1344.
-
(2004)
Genes Dev
, vol.18
, pp. 1331-1344
-
-
Stojic, L.1
Mojas, N.2
Cejka, P.3
Di Pietro, M.4
Ferrari, S.5
Marra, G.6
Jiricny, J.7
-
78
-
-
0033555260
-
A role for ATR in the DNA damage-induced phosphorylation of p53
-
R.S. Tibbetts, K.M. Brumbaugh, J.M.Williams, J.N. Sarkaria, W.A. Cliby, S.Y. Shieh, Y. Taya, C. Prives and R.T. Abraham, A role for ATR in the DNA damage-induced phosphorylation of p53, Genes Dev 13 (1999), 152-157.
-
(1999)
Genes Dev
, vol.13
, pp. 152-157
-
-
Tibbetts, R.S.1
Brumbaugh, K.M.2
Williams, J.M.3
Sarkaria, J.N.4
Cliby, W.A.5
Shieh, S.Y.6
Taya, Y.7
Prives, C.8
Abraham, R.T.9
-
79
-
-
0033607055
-
HMutSalpha-and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage
-
D.R. Duckett, S.M. Bronstein, Y. Taya and P. Modrich, hMutSalpha-and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage, Proc Natl Acad Sci USA 96 (1999), 12384-12388.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12384-12388
-
-
Duckett, D.R.1
Bronstein, S.M.2
Taya, Y.3
Modrich, P.4
-
80
-
-
1842715589
-
Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine
-
M.J. Hickman and L.D. Samson, Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine, Mol Cell 14 (2004), 105-116.
-
(2004)
Mol Cell
, vol.14
, pp. 105-116
-
-
Hickman, M.J.1
Samson, L.D.2
-
81
-
-
0030877559
-
Differential induction of c-Jun NH2-terminal kinase and c-Abl kinase in DNA mismatch repair-proficient and-deficient cells exposed to cisplatin
-
A. Nehme, R. Baskaran, S. Aebi, D. Fink, S. Nebel, B. Cenni, J.Y. Wang, S.B. Howell and R.D. Christen, Differential induction of c-Jun NH2-terminal kinase and c-Abl kinase in DNA mismatch repair-proficient and-deficient cells exposed to cisplatin, Cancer Res 57 (1997), 3253-3257.
-
(1997)
Cancer Res
, vol.57
, pp. 3253-3257
-
-
Nehme, A.1
Baskaran, R.2
Aebi, S.3
Fink, D.4
Nebel, S.5
Cenni, B.6
Wang, J.Y.7
Howell, S.B.8
Christen, R.D.9
-
82
-
-
0033600234
-
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
-
J.G. Gong, A. Costanzo, H.Q. Yang, G. Melino, W.G. Kaelin Jr., M. Levrero and J.Y. Wang, The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage, Nature 399 (1999), 806-809.
-
(1999)
Nature
, vol.399
, pp. 806-809
-
-
Gong, J.G.1
Costanzo, A.2
Yang, H.Q.3
Melino, G.4
Kaelin Jr., W.G.5
Levrero, M.6
Wang, J.Y.7
-
83
-
-
0035392965
-
Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine- mediated cell death and cell cycle responses
-
M. Meyers, M.W. Wagner, H.S. Hwang, T.J. Kinsella and D.A. Boothman, Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses, Cancer Res 61 (2001), 5193-5201.
-
(2001)
Cancer Res
, vol.61
, pp. 5193-5201
-
-
Meyers, M.1
Wagner, M.W.2
Hwang, H.S.3
Kinsella, T.J.4
Boothman, D.A.5
-
84
-
-
0027936057
-
Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation
-
M. Koi, A. Umar, D.P. Chauhan, S.P. Cherian, J.M. Carethers, T.A. Kunkel and C.R. Boland, Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation, Cancer Res 54 (1994), 4308-4312.
-
(1994)
Cancer Res
, vol.54
, pp. 4308-4312
-
-
Koi, M.1
Umar, A.2
Chauhan, D.P.3
Cherian, S.P.4
Carethers, J.M.5
Kunkel, T.A.6
Boland, C.R.7
-
85
-
-
3142658762
-
Hypersensitivity of tumor cell lines with microsatellite instability to DNA double strand break producing chemotherapeutic agent bleomycin
-
H.R. Li, E.I. Shagisultanova, K. Yamashita, Z. Piao, M. Perucho and S.R. Malkhosyan, Hypersensitivity of tumor cell lines with microsatellite instability to DNA double strand break producing chemotherapeutic agent bleomycin, Cancer Res 64 (2004), 4760-4767.
-
(2004)
Cancer Res
, vol.64
, pp. 4760-4767
-
-
Li, H.R.1
Shagisultanova, E.I.2
Yamashita, K.3
Piao, Z.4
Perucho, M.5
Malkhosyan, S.R.6
-
86
-
-
1542269016
-
Killing and mutagenic actions of dacarbazine, a chemotherapeutic alkylating agent, on human and mouse cells: Effects of Mgmt and Mlh1 mutations
-
M. Sanada, Y. Takagi, R. Ito and M. Sekiguchi, Killing and mutagenic actions of dacarbazine, a chemotherapeutic alkylating agent, on human and mouse cells: effects of Mgmt and Mlh1 mutations, DNA Repair 3 (2004), 413-420.
-
(2004)
DNA Repair
, vol.3
, pp. 413-420
-
-
Sanada, M.1
Takagi, Y.2
Ito, R.3
Sekiguchi, M.4
-
87
-
-
27844605955
-
DNA mismatch repair deficiency, resistance to cancer chemotherapy and the development of hypersensitive agents
-
K. Pors and L.H. Patterson, DNA mismatch repair deficiency, resistance to cancer chemotherapy and the development of hypersensitive agents, Curr Top Med Chem 5 (2005), 1133-1149.
-
(2005)
Curr Top Med Chem
, vol.5
, pp. 1133-1149
-
-
Pors, K.1
Patterson, L.H.2
|