Tumor-infiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinoma

Cancer

Volumn 91, Issue 12, 2001, Pages 2417-2422

  Smyrk, Thomas C ^a   Watson, Patrice ^b   Kaul, Karen ^c   Lynch, Henry T ^a  

^a EVANSTON HOSPITAL   (United States)

^b CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MAYO CLINIC   (United States)

Author keywords

Colorectal carcinoma; Hereditary nonpolyposis colorectal carcinoma (HNPCC); Microsatellite instability; Pathology; Tumor infiltrating lymphocytes (TILs)

Indexed keywords

ARTICLE; CLINICAL FEATURE; COLORECTAL CARCINOMA; HUMAN; HUMAN TISSUE; LYMPHOCYTE COUNT; LYMPHOCYTIC INFILTRATION; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; MICROSCOPY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

COLORECTAL NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; HUMANS; LYMPHOCYTES, TUMOR-INFILTRATING; MICROSATELLITE REPEATS; SENSITIVITY AND SPECIFICITY;

EID: 0035875903     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0142(20010615)91:12<2417::AID-CNCR1276>3.0.CO;2-U     Document Type: Article

References (23)

1. Prolonged survival as a component of hereditary breast and nonpolyposis colon cancer
2. Natural history of hereditary cancer of the breast and colon
3. Better survival rates in patients with MLH1-associated hereditary colorectal cancer
4. Colorectal carcinoma survival among hereditary nonpolyposis colorectal cancer family members
5. Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
6. Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer
7. Prognostic significance of extensive micro-satellite instability in sporadic clinicopathological stage C colorectal cancer
8. Microsatellite instability is not an independent prognostic factor
9. Microsatellite instability in sporadic colorectal carcinoma is not an indicator of prognosis
10. The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells
11. Mismatch repair proficiency and in vitro response to 5-fluorouracil
12. Morphology of sporadic colorectal cancer with DNA replication errors
13. Histopathologic features associated with microsatellite instability in colorectal carcinomas
14. A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
15. Diagnostic microsatellite instability: Definition and correlation with mismatch repair protein expression
16. Population-based molecular detection of hereditary nonpolyposis colorectal cancer
17. Immunohistochemistry for hMLH1 and hMSH2: A practical test for DNA mismatch repair-deficient tumors
18. High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability
19. Cytotoxic phenotype of tumor infiltrating lymphocytes in medullary carcinoma of the breast
20. TIA-1 positive tumor-infiltrating lymphocytes in nevi and melanomas
21. Fas ligand expression in primary colon adenocarcinomas: Evidence that the Fas counterattack is a prevalent mechanism of immune evasion in human colon cancer
22. FasL is more frequently expressed in liver metastases of colorectal cancer than in matched primary carcinomas