메뉴 건너뛰기




Volumn 23, Issue 25, 2003, Pages 8682-8691

Enhanced oligodendrocyte survival after spinal cord injury in bax-deficient mice and mice with delayed Wallerian degeneration

Author keywords

Apoptosis; Bax deficiency; Bax ; Immunohistochemistry; Oligodendrocyte death; Spinal cord hemisection; Wallerian degeneration; Wlds mutation

Indexed keywords

APC PROTEIN; CASPASE 3; CYCLOSPORIN A; KAINIC ACID; PROTEIN BAX; STAUROSPORINE;

EID: 0141758289     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-25-08682.2003     Document Type: Article
Times cited : (104)

References (59)
  • 1
    • 0032720031 scopus 로고    scopus 로고
    • Apoptotic cells associated with Wallerian degeneration after experimental spinal cord injury: A possible mechanism of oligodendroglial death
    • Abe Y, Yamamoto T, Sugiyama Y, Watanabe T, Saito N, Kayama H, Kumagai T (1999) Apoptotic cells associated with Wallerian degeneration after experimental spinal cord injury: a possible mechanism of oligodendroglial death. J Neurotrauma 16:945-952.
    • (1999) J Neurotrauma , vol.16 , pp. 945-952
    • Abe, Y.1    Yamamoto, T.2    Sugiyama, Y.3    Watanabe, T.4    Saito, N.5    Kayama, H.6    Kumagai, T.7
  • 3
    • 0033104429 scopus 로고    scopus 로고
    • Motor neuron degeneration is attenuated in Bax-deficient neurons in vitro
    • Bar-Peled O, Knudson M, Korsmeyer SJ, Rothstein JD (1999) Motor neuron degeneration is attenuated in Bax-deficient neurons in vitro. J Neurosci Res 55:542-556.
    • (1999) J Neurosci Res , vol.55 , pp. 542-556
    • Bar-Peled, O.1    Knudson, M.2    Korsmeyer, S.J.3    Rothstein, J.D.4
  • 5
    • 0027299467 scopus 로고
    • Multiple extracellular signals are required for long-term oligodendrocyte survival
    • Barres BA, Schmid R, Sendnter M, Raff MC (1993) Multiple extracellular signals are required for long-term oligodendrocyte survival. Dev 118:283-295.
    • (1993) Dev , vol.118 , pp. 283-295
    • Barres, B.A.1    Schmid, R.2    Sendnter, M.3    Raff, M.C.4
  • 6
    • 0033793564 scopus 로고    scopus 로고
    • Review of current evidence for apoptosis after spinal cord injury
    • Beattie MS, Farooqui AA, Bresnahan JC (2000) Review of current evidence for apoptosis after spinal cord injury. J Neurotrauma 17:915-925.
    • (2000) J Neurotrauma , vol.17 , pp. 915-925
    • Beattie, M.S.1    Farooqui, A.A.2    Bresnahan, J.C.3
  • 8
    • 0025142474 scopus 로고
    • Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells
    • Bogler O, Wren D, Barnett SC, Land H, Noble M (1990) Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells. Proc Natl Acad Sci USA 87:6368-6372.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6368-6372
    • Bogler, O.1    Wren, D.2    Barnett, S.C.3    Land, H.4    Noble, M.5
  • 10
    • 0025764472 scopus 로고
    • Delayed response to denervation in muscles of C57BL/Ola mice
    • Brown MC, Booth CM, Lunn ER, Perry VH (1991) Delayed response to denervation in muscles of C57BL/Ola mice. Neuroscience 43:279-283.
    • (1991) Neuroscience , vol.43 , pp. 279-283
    • Brown, M.C.1    Booth, C.M.2    Lunn, E.R.3    Perry, V.H.4
  • 11
    • 0026683408 scopus 로고
    • Consequences of slow Wallerian degeneration for regenerating motor and sensory axons
    • Brown MC, Lunn ER, Perry VH (1992) Consequences of slow Wallerian degeneration for regenerating motor and sensory axons. J Neurobiol 23:521-536.
    • (1992) J Neurobiol , vol.23 , pp. 521-536
    • Brown, M.C.1    Lunn, E.R.2    Perry, V.H.3
  • 12
    • 0035961212 scopus 로고    scopus 로고
    • Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in rats
    • Casha S, Yu WR, Fehlings MG (2001) Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in rats. Neuroscience 103:203-218.
    • (2001) Neuroscience , vol.103 , pp. 203-218
    • Casha, S.1    Yu, W.R.2    Fehlings, M.G.3
  • 13
    • 0001343810 scopus 로고    scopus 로고
    • Bcl-2 promotes regeneration of severed axons in mammalian CNS
    • Chen DF, Schneider GE, Martinou J-C, Tonegawa S (1997) Bcl-2 promotes regeneration of severed axons in mammalian CNS. Nature 385:434-439.
    • (1997) Nature , vol.385 , pp. 434-439
    • Chen, D.F.1    Schneider, G.E.2    Martinou, J.-C.3    Tonegawa, S.4
  • 15
    • 0031015075 scopus 로고    scopus 로고
    • Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys
    • Crowe MJ, Bresnahan JC, Shuman SL, Masters JN, Beattie MS (1997) Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nat Med 3:73-76.
    • (1997) Nat Med , vol.3 , pp. 73-76
    • Crowe, M.J.1    Bresnahan, J.C.2    Shuman, S.L.3    Masters, J.N.4    Beattie, M.S.5
  • 16
    • 0028239631 scopus 로고
    • Amphoterin (P30, HMG-1) and RIP are early markers of oligodendrocytes in the developing rat spinal cord
    • Daston MM, Ratner N (1994) Amphoterin (P30, HMG-1) and RIP are early markers of oligodendrocytes in the developing rat spinal cord. J Neurocytology 23:323-332.
    • (1994) J Neurocytology , vol.23 , pp. 323-332
    • Daston, M.M.1    Ratner, N.2
  • 19
    • 0024310302 scopus 로고
    • In situ demonstration of mature oligodendrocytes and their processes: An immunocytochemical study with a new monoclonal antibody, rip
    • Friedman B, Hockfield S, Black JA, Woodruff KA, Waxman SG (1989) In situ demonstration of mature oligodendrocytes and their processes: an immunocytochemical study with a new monoclonal antibody, rip. Glia 2:380-390.
    • (1989) Glia , vol.2 , pp. 380-390
    • Friedman, B.1    Hockfield, S.2    Black, J.A.3    Woodruff, K.A.4    Waxman, S.G.5
  • 20
    • 0029001403 scopus 로고
    • Up-regulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain
    • Gillardon F, Wickert H, Zimmermann M (1995) Up-regulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain. Neurosci Lett 192:85-88.
    • (1995) Neurosci Lett , vol.192 , pp. 85-88
    • Gillardon, F.1    Wickert, H.2    Zimmermann, M.3
  • 22
    • 0343580512 scopus 로고    scopus 로고
    • "Semifree-floating" treatment: A simple and fast method to process consecutive sections for immunohistochemistry and neuronal tracing
    • Herzog A, Brosamle C (1997) "Semifree-floating" treatment: a simple and fast method to process consecutive sections for immunohistochemistry and neuronal tracing. J Neurosci Methods 72:57-63.
    • (1997) J Neurosci Methods , vol.72 , pp. 57-63
    • Herzog, A.1    Brosamle, C.2
  • 23
    • 0029768094 scopus 로고    scopus 로고
    • Structural recovery in lesioned adult mammalian spinal cord by x-irradiation of the lesion site
    • Kalderon N, Fuks Z (1996) Structural recovery in lesioned adult mammalian spinal cord by x-irradiation of the lesion site. Proc Natl Acad Sci USA 93:11179-11184.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11179-11184
    • Kalderon, N.1    Fuks, Z.2
  • 25
    • 0028956550 scopus 로고
    • Regulators of cell death
    • Korsmeyer SJ (1995) Regulators of cell death. Trends Genet 11:101-105.
    • (1995) Trends Genet , vol.11 , pp. 101-105
    • Korsmeyer, S.J.1
  • 26
    • 0033119372 scopus 로고    scopus 로고
    • Bcl-2 gene family and the regulation of programmed cell death
    • Korsmeyer SJ (1999) Bcl-2 gene family and the regulation of programmed cell death. Cancer Res 59:1693-1700.
    • (1999) Cancer Res , vol.59 , pp. 1693-1700
    • Korsmeyer, S.J.1
  • 28
    • 0032828302 scopus 로고    scopus 로고
    • Apoptosis of oligodendrocytes occurs for long distances away from the primary injury after compression trauma to rat spinal cord
    • Li GL, Farooque M, Holtz A (1999) Apoptosis of oligodendrocytes occurs for long distances away from the primary injury after compression trauma to rat spinal cord. Acta Neuropathol 98:473-480.
    • (1999) Acta Neuropathol , vol.98 , pp. 473-480
    • Li, G.L.1    Farooque, M.2    Holtz, A.3
  • 30
    • 0032033423 scopus 로고    scopus 로고
    • In vivo Bcl-2 oncogene neuronal expression in the rat spinal cord
    • Lou J, Lenke LG, Xu F, O'Brien M (1998) In vivo Bcl-2 oncogene neuronal expression in the rat spinal cord. Spine 23:517-523.
    • (1998) Spine , vol.23 , pp. 517-523
    • Lou, J.1    Lenke, L.G.2    Xu, F.3    O'Brien, M.4
  • 31
    • 0030773792 scopus 로고    scopus 로고
    • The pathobiology of the oligodendrocyte
    • Ludwin SK (1997) The pathobiology of the oligodendrocyte. J Neuropathol Exp Neurol 56:111-124.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 111-124
    • Ludwin, S.K.1
  • 32
    • 0026748618 scopus 로고
    • Delayed Wallerian degeneration in the central nervous system of Ola mice: An ultrastructural study
    • Ludwin SK, Bisby MA (1992) Delayed Wallerian degeneration in the central nervous system of Ola mice: an ultrastructural study. J Neurol Sci 109:140-147.
    • (1992) J Neurol Sci , vol.109 , pp. 140-147
    • Ludwin, S.K.1    Bisby, M.A.2
  • 33
    • 0037083204 scopus 로고    scopus 로고
    • Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent
    • Martin LJ, Liu Z (2002) Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent. J Neurobiol 50:181-197.
    • (2002) J Neurobiol , vol.50 , pp. 181-197
    • Martin, L.J.1    Liu, Z.2
  • 34
    • 0037006387 scopus 로고    scopus 로고
    • Spinal cord injury: Doable therapeutics
    • McDonald JW, Sadowsky C (2002) Spinal cord injury: doable therapeutics. Lancet 359:417-425.
    • (2002) Lancet , vol.359 , pp. 417-425
    • McDonald, J.W.1    Sadowsky, C.2
  • 35
    • 0029804767 scopus 로고    scopus 로고
    • Cyclosporine induces neuronal apoptosis and selective oligodendrocyte death in cortical cultures
    • McDonald JW, Goldberg MP, Gwag BJ, Chi S-I, Choi DW (1996) Cyclosporine induces neuronal apoptosis and selective oligodendrocyte death in cortical cultures. Ann Neurol 40:750-758.
    • (1996) Ann Neurol , vol.40 , pp. 750-758
    • McDonald, J.W.1    Goldberg, M.P.2    Gwag, B.J.3    Chi, S.-I.4    Choi, D.W.5
  • 36
    • 0031952612 scopus 로고    scopus 로고
    • Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity
    • McDonald JW, Althomsons SP, Hyrc KL, Choi DW, Goldberg MP (1998) Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity. Nat Med 4:291-297.
    • (1998) Nat Med , vol.4 , pp. 291-297
    • McDonald, J.W.1    Althomsons, S.P.2    Hyrc, K.L.3    Choi, D.W.4    Goldberg, M.P.5
  • 37
    • 0032759046 scopus 로고    scopus 로고
    • Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord
    • McDonald JW, Liu X-Z, Qu Y, Liu S, Mickey SK, Turetsky D, Gottlieb DI, Choi DW (1999) Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. Nat Med 5:1410-1412.
    • (1999) Nat Med , vol.5 , pp. 1410-1412
    • McDonald, J.W.1    Liu, X.-Z.2    Qu, Y.3    Liu, S.4    Mickey, S.K.5    Turetsky, D.6    Gottlieb, D.I.7    Choi, D.W.8
  • 38
    • 0025200507 scopus 로고
    • FGF modulates the PDGF-driven pathway of oligodendrocyte development
    • McKinnon RD, Matsui T, Dubois-Dalcq M, Aaronson SA (1990) FGF modulates the PDGF-driven pathway of oligodendrocyte development. Neuron 5:603-614.
    • (1990) Neuron , vol.5 , pp. 603-614
    • McKinnon, R.D.1    Matsui, T.2    Dubois-Dalcq, M.3    Aaronson, S.A.4
  • 39
    • 0025083378 scopus 로고
    • Effect of optic nerve transection upon myelin protein gene expression by oligodendrocytes: Evidence for axonal influences on gene expression
    • McPhilemy K, Mitchell LS, Griffiths IR, Morrison S, Deary AW, Sommer I, Kennedy PGE (1990) Effect of optic nerve transection upon myelin protein gene expression by oligodendrocytes: evidence for axonal influences on gene expression. J Neurocytol 19:494-503.
    • (1990) J Neurocytol , vol.19 , pp. 494-503
    • McPhilemy, K.1    Mitchell, L.S.2    Griffiths, I.R.3    Morrison, S.4    Deary, A.W.5    Sommer, I.6    Kennedy, P.G.E.7
  • 40
    • 0025775819 scopus 로고
    • Loss of axonal contact causes down-regulation of the PLP gene in oligodendrocytes: Evidence from partial lesions of the optic nerve
    • McPhilemy K, Griffiths IR, Mitchell LS, Kennedy PGE (1991) Loss of axonal contact causes down-regulation of the PLP gene in oligodendrocytes: evidence from partial lesions of the optic nerve. Neuropathol Appl Neurobiol 17:275-287.
    • (1991) Neuropathol Appl Neurobiol , vol.17 , pp. 275-287
    • McPhilemy, K.1    Griffiths, I.R.2    Mitchell, L.S.3    Kennedy, P.G.E.4
  • 41
    • 0031828871 scopus 로고    scopus 로고
    • Suppression of developmental retinal cell death but not of photoreceptor degeneration in Bax-deficient mice
    • Mosinger Ogilvie J, Deckwerth TL, Knudson CM, Korsmeyer SJ (1998) Suppression of developmental retinal cell death but not of photoreceptor degeneration in Bax-deficient mice. Invest Ophthalmol Vis Sci 39:1713-1720.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 1713-1720
    • Mosinger Ogilvie, J.1    Deckwerth, T.L.2    Knudson, C.M.3    Korsmeyer, S.J.4
  • 42
    • 0025316350 scopus 로고
    • Evidence that the rate of Wallerian degeneration is controlled by a single autosomal dominant gene
    • Perry VH, Lunn ER, Brown MC, Cahusac S, Gordon S (1989) Evidence that the rate of Wallerian degeneration is controlled by a single autosomal dominant gene. Eur J Neurosci 2:408-413.
    • (1989) Eur J Neurosci , vol.2 , pp. 408-413
    • Perry, V.H.1    Lunn, E.R.2    Brown, M.C.3    Cahusac, S.4    Gordon, S.5
  • 43
    • 0025110838 scopus 로고
    • Evidence that very slow Wallerian degeneration in C57BL/Ola mice is an intrinsic property of the peripheral nerve
    • Perry VH, Brown MC, Lunn ER, Tree P, Gordon S (1990) Evidence that very slow Wallerian degeneration in C57BL/Ola mice is an intrinsic property of the peripheral nerve. Eur J Neurosci 2:802-808.
    • (1990) Eur J Neurosci , vol.2 , pp. 802-808
    • Perry, V.H.1    Brown, M.C.2    Lunn, E.R.3    Tree, P.4    Gordon, S.5
  • 44
    • 0025974211 scopus 로고
    • Very slow retrograde and Wallerian degeneration in the CNS of C57BL/Ola mice
    • Perry VH, Brown MC, Lunn ER (1991) Very slow retrograde and Wallerian degeneration in the CNS of C57BL/Ola mice. Eur J Neurosci 3:102-105.
    • (1991) Eur J Neurosci , vol.3 , pp. 102-105
    • Perry, V.H.1    Brown, M.C.2    Lunn, E.R.3
  • 45
    • 0032838089 scopus 로고    scopus 로고
    • Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury
    • Popovich PG, Guan Z, Wei P, Huitinga I, van Rooijen N, Stokes BT (1999) Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. Exp Neurol 158:351-365.
    • (1999) Exp Neurol , vol.158 , pp. 351-365
    • Popovich, P.G.1    Guan, Z.2    Wei, P.3    Huitinga, I.4    Van Rooijen, N.5    Stokes, B.T.6
  • 47
    • 0034589391 scopus 로고    scopus 로고
    • In vivo neuroprotection of injured CNS neurons by a single injection of a DNA plasmid encoding the Bcl-2 gene
    • Saavedra RA, Murray M, de Lacalle S, Tessler A (2000) In vivo neuroprotection of injured CNS neurons by a single injection of a DNA plasmid encoding the Bcl-2 gene. Prog Brain Res 128:365-372.
    • (2000) Prog Brain Res , vol.128 , pp. 365-372
    • Saavedra, R.A.1    Murray, M.2    De Lacalle, S.3    Tessler, A.4
  • 49
    • 0029900303 scopus 로고    scopus 로고
    • Degeneration and regeneration of axons in the lesion spinal cord
    • Schwab ME, Bartholdi D (1997) Degeneration and regeneration of axons in the lesion spinal cord. Physiol Rev 76:319-370.
    • (1997) Physiol Rev , vol.76 , pp. 319-370
    • Schwab, M.E.1    Bartholdi, D.2
  • 50
    • 0030695396 scopus 로고    scopus 로고
    • Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats
    • Shuman SL, Bresnahan JC, Beattie MS (1997) Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats. J Neurosci Res 50:798-808.
    • (1997) J Neurosci Res , vol.50 , pp. 798-808
    • Shuman, S.L.1    Bresnahan, J.C.2    Beattie, M.S.3
  • 51
    • 0032790541 scopus 로고    scopus 로고
    • Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury
    • Springer JE, Azbill RD, Knapp PE (1999) Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury. Nat Med 5:943-946.
    • (1999) Nat Med , vol.5 , pp. 943-946
    • Springer, J.E.1    Azbill, R.D.2    Knapp, P.E.3
  • 52
    • 0033380656 scopus 로고    scopus 로고
    • Apoptosis and necrosis in cerebrovascular disease
    • Snider BJ, Gottron FJ, Choi DW (1999) Apoptosis and necrosis in cerebrovascular disease. Ann NY Acad Sci 893:243-253.
    • (1999) Ann NY Acad Sci , vol.893 , pp. 243-253
    • Snider, B.J.1    Gottron, F.J.2    Choi, D.W.3
  • 53
    • 0033535123 scopus 로고    scopus 로고
    • DNA plasmid that codes for human Bcl-2 gene preserves axotomized Clarke's nucleus neurons and reduces atrophy after spinal cord hemisection in adult rats
    • Takahashi K, Schwarz E, Ljubetic C, Murray M, Tessler A, Saavedra RA (1999) DNA plasmid that codes for human Bcl-2 gene preserves axotomized Clarke's nucleus neurons and reduces atrophy after spinal cord hemisection in adult rats. J Comp Neurol 404:159-171.
    • (1999) J Comp Neurol , vol.404 , pp. 159-171
    • Takahashi, K.1    Schwarz, E.2    Ljubetic, C.3    Murray, M.4    Tessler, A.5    Saavedra, R.A.6
  • 57
    • 0031239077 scopus 로고    scopus 로고
    • Experimental spinal cord injury: Wallerian degeneration in the dorsal column is followed by revascularization, glial proliferation, and nerve regeneration
    • Zhang Z, Guth L (1997) Experimental spinal cord injury: Wallerian degeneration in the dorsal column is followed by revascularization, glial proliferation, and nerve regeneration. Exp Neurol 147:159-171.
    • (1997) Exp Neurol , vol.147 , pp. 159-171
    • Zhang, Z.1    Guth, L.2
  • 59
    • 0031889122 scopus 로고    scopus 로고
    • s) that delays cellular responses to injury
    • s) that delays cellular responses to injury. Exp Neurol 149:221-229.
    • (1998) Exp Neurol , vol.149 , pp. 221-229
    • Zhang, Z.1    Guth, L.2    Steward, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.