-
1
-
-
0031133179
-
Antisense down-regulation of metallothionein induces growth arrest and apoptosis in human breast carcinoma cells
-
Abdel-Mageed A, Agrawal KC. (1997). Antisense down-regulation of metallothionein induces growth arrest and apoptosis in human breast carcinoma cells. Cancer Gene Ther 4: 199-207.
-
(1997)
Cancer Gene Ther
, vol.4
, pp. 199-207
-
-
Abdel-Mageed, A.1
Agrawal, K.C.2
-
2
-
-
31944444234
-
Cancer-specific mutations in PIK3CA are oncogenic in vivo
-
Bader AG, Kang S, Vogt PK. (2006). Cancer-specific mutations in PIK3CA are oncogenic in vivo. Proc Natl Acad Sci USA 103: 1475-1479.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1475-1479
-
-
Bader, A.G.1
Kang, S.2
Vogt, P.K.3
-
3
-
-
0037421204
-
Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma
-
Brock C, Schaefer M, Reusch HP, Czupalla C, Michalke M, Spicher K et al. (2003). Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma. J Cell Biol 160: 89-99.
-
(2003)
J Cell Biol
, vol.160
, pp. 89-99
-
-
Brock, C.1
Schaefer, M.2
Reusch, H.P.3
Czupalla, C.4
Michalke, M.5
Spicher, K.6
-
4
-
-
15444349266
-
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer
-
Cairns P, Okami K, Halachmi S, Halachmi N, Esteller M, Herman JG et al. (1997). Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. Cancer Res 57: 4997-5000.
-
(1997)
Cancer Res
, vol.57
, pp. 4997-5000
-
-
Cairns, P.1
Okami, K.2
Halachmi, S.3
Halachmi, N.4
Esteller, M.5
Herman, J.G.6
-
5
-
-
7444250290
-
Mutation of the PIK3CA gene in ovarian and breast cancer
-
Campbell IG, Russell SE, Choong DY, Montgomery KG, Ciavarella ML, Hooi CS et al. (2004). Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res 64: 7678-7681.
-
(2004)
Cancer Res
, vol.64
, pp. 7678-7681
-
-
Campbell, I.G.1
Russell, S.E.2
Choong, D.Y.3
Montgomery, K.G.4
Ciavarella, M.L.5
Hooi, C.S.6
-
6
-
-
0036172306
-
Chemokine signalling: Pivoting around multiple phosphoinositide 3-kinases
-
Curnock AP, Logan MK, Ward SG. (2002). Chemokine signalling: pivoting around multiple phosphoinositide 3-kinases. Immunology 105: 125-136.
-
(2002)
Immunology
, vol.105
, pp. 125-136
-
-
Curnock, A.P.1
Logan, M.K.2
Ward, S.G.3
-
7
-
-
0037020224
-
Direct effects of caffeine and theophylline on p110 delta and other phosphoinositide 3-kinases
-
Foukas LC, Daniele N, Ktori C, Anderson KE, Jensen J, Shepherd PR. (2002). Direct effects of caffeine and theophylline on p110 delta and other phosphoinositide 3-kinases. J Biol Chem 277: 37124-37130.
-
(2002)
J Biol Chem
, vol.277
, pp. 37124-37130
-
-
Foukas, L.C.1
Daniele, N.2
Ktori, C.3
Anderson, K.E.4
Jensen, J.5
Shepherd, P.R.6
-
8
-
-
0037111475
-
Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors
-
Freeburn RW, Wright KL, Burgess SJ, Astoul E, Cantrell DA, Ward SG. (2002). Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors. J Immunol 169: 5441-5450.
-
(2002)
J Immunol
, vol.169
, pp. 5441-5450
-
-
Freeburn, R.W.1
Wright, K.L.2
Burgess, S.J.3
Astoul, E.4
Cantrell, D.A.5
Ward, S.G.6
-
9
-
-
2342504508
-
Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers
-
Goel A, Arnold CN, Niedzwiecki D, Carethers JM, Dowell JM, Wasserman L et al. (2004). Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers. Cancer Res 64: 3014-3021.
-
(2004)
Cancer Res
, vol.64
, pp. 3014-3021
-
-
Goel, A.1
Arnold, C.N.2
Niedzwiecki, D.3
Carethers, J.M.4
Dowell, J.M.5
Wasserman, L.6
-
11
-
-
32044466838
-
Exploiting the PI3K/AKT pathway for cancer drug discovery
-
Hennessy BT, Smith DL, Ram PT, Lu Y, Mills GB. (2005). Exploiting the PI3K/AKT pathway for cancer drug discovery. Nat Rev Drug Discov 4: 988-1004.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 988-1004
-
-
Hennessy, B.T.1
Smith, D.L.2
Ram, P.T.3
Lu, Y.4
Mills, G.B.5
-
12
-
-
33646370512
-
BCR-ABL regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation and is required for proliferation and drug resistance
-
Hickey FB, Cotter TG. (2006). BCR-ABL regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation and is required for proliferation and drug resistance. J Biol Chem 281: 2441-2450.
-
(2006)
J Biol Chem
, vol.281
, pp. 2441-2450
-
-
Hickey, F.B.1
Cotter, T.G.2
-
13
-
-
0034635452
-
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation
-
Hirsch E, Katanaev VL, Garlanda C, Azzolino O, Pirola L, Silengo L et al. (2000). Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science 287: 1049-1053.
-
(2000)
Science
, vol.287
, pp. 1049-1053
-
-
Hirsch, E.1
Katanaev, V.L.2
Garlanda, C.3
Azzolino, O.4
Pirola, L.5
Silengo, L.6
-
14
-
-
0032472913
-
Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase
-
Jimenez C, Jones DR, Rodriguez-Viciana P, Gonzalez-Garcia A, Leonardo E, Wennstrom S et al. (1998). Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase. EMBO J 17: 743-753.
-
(1998)
EMBO J
, vol.17
, pp. 743-753
-
-
Jimenez, C.1
Jones, D.R.2
Rodriguez-Viciana, P.3
Gonzalez-Garcia, A.4
Leonardo, E.5
Wennstrom, S.6
-
15
-
-
10644295480
-
Substitution of feline leukemia virus long terminal repeat sequences into murine leukemia virus alters the pattern of insertional activation and identifies new common insertion sites
-
Johnson C, Lobelle-Rich PA, Puetter A, Levy LS. (2005). Substitution of feline leukemia virus long terminal repeat sequences into murine leukemia virus alters the pattern of insertional activation and identifies new common insertion sites. J Virol 79: 57-66.
-
(2005)
J Virol
, vol.79
, pp. 57-66
-
-
Johnson, C.1
Lobelle-Rich, P.A.2
Puetter, A.3
Levy, L.S.4
-
16
-
-
0036111802
-
Expression of a mutated form of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase in a Hodgkin's lymphoma-derived cell line (CO)
-
Jucker M, Sudel K, Horn S, Sickel M, Wegner W, Fiedler W et al. (2002). Expression of a mutated form of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase in a Hodgkin's lymphoma-derived cell line (CO). Leukemia 16: 894-901.
-
(2002)
Leukemia
, vol.16
, pp. 894-901
-
-
Jucker, M.1
Sudel, K.2
Horn, S.3
Sickel, M.4
Wegner, W.5
Fiedler, W.6
-
17
-
-
25444482837
-
Mutated PI 3-kinases: Cancer targets on a silver platter
-
Kang S, Bader AG, Zhao L, Vogt PK. (2005). Mutated PI 3-kinases: cancer targets on a silver platter. Cell Cycle 4: 578-581.
-
(2005)
Cell Cycle
, vol.4
, pp. 578-581
-
-
Kang, S.1
Bader, A.G.2
Zhao, L.3
Vogt, P.K.4
-
18
-
-
31944448780
-
Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase
-
Kang S, Denley A, Vanhaesebroeck B, Vogt PK. (2006). Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase. Proc Natl Acad Sci USA 103: 1289-1294.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1289-1294
-
-
Kang, S.1
Denley, A.2
Vanhaesebroeck, B.3
Vogt, P.K.4
-
19
-
-
6344246440
-
PTEN promoter is methylated in a proportion of invasive breast cancers
-
Khan S, Kumagai T, Vora J, Bose N, Sehgal I, Koeffler PH et al. (2004). PTEN promoter is methylated in a proportion of invasive breast cancers. Int J Cancer 112: 407-410.
-
(2004)
Int J Cancer
, vol.112
, pp. 407-410
-
-
Khan, S.1
Kumagai, T.2
Vora, J.3
Bose, N.4
Sehgal, I.5
Koeffler, P.H.6
-
20
-
-
0038549067
-
PI3K in lymphocyte development, differentiation and activation
-
Okkenhaug K, Vanhaesebroeck B. (2003). PI3K in lymphocyte development, differentiation and activation. Nat Rev Immunol 3: 317-330.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 317-330
-
-
Okkenhaug, K.1
Vanhaesebroeck, B.2
-
21
-
-
13944284494
-
Oncogenic mutations of PIK3CA in human cancers
-
Samuels Y, Velculescu VE. (2004). Oncogenic mutations of PIK3CA in human cancers. Cell Cycle 3: 1221-1224.
-
(2004)
Cell Cycle
, vol.3
, pp. 1221-1224
-
-
Samuels, Y.1
Velculescu, V.E.2
-
22
-
-
0034635264
-
Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration
-
Sasaki T, Irie-Sasaki J, Jones RG, Oliveira-dos-Santos AJ, Stanford WL, Bolon B et al. (2000). Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration. Science 287: 1040-1046.
-
(2000)
Science
, vol.287
, pp. 1040-1046
-
-
Sasaki, T.1
Irie-Sasaki, J.2
Jones, R.G.3
Oliveira-dos-Santos, A.J.4
Stanford, W.L.5
Bolon, B.6
-
23
-
-
0032590011
-
PIK3CA is implicated as an oncogene in ovarian cancer
-
Shayesteh L, Lu Y, Kuo WL, Baldocchi R, Godfrey T, Collins C et al. (1999). PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet 21: 99-102.
-
(1999)
Nat Genet
, vol.21
, pp. 99-102
-
-
Shayesteh, L.1
Lu, Y.2
Kuo, W.L.3
Baldocchi, R.4
Godfrey, T.5
Collins, C.6
-
24
-
-
0028334738
-
A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits
-
Stephens L, Smrcka A, Cooke FT, Jackson TR, Sternweis PC, Hawkins PT. (1994). A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits. Cell 77: 83-93.
-
(1994)
Cell
, vol.77
, pp. 83-93
-
-
Stephens, L.1
Smrcka, A.2
Cooke, F.T.3
Jackson, T.R.4
Sternweis, P.C.5
Hawkins, P.T.6
-
25
-
-
0030887632
-
The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101
-
Stephens LR, Eguinoa A, Erdjument-Bromage H, Lui M, Cooke F, Coadwell J et al. (1997). The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101. Cell 89: 105-114.
-
(1997)
Cell
, vol.89
, pp. 105-114
-
-
Stephens, L.R.1
Eguinoa, A.2
Erdjument-Bromage, H.3
Lui, M.4
Cooke, F.5
Coadwell, J.6
-
26
-
-
15744363780
-
p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma
-
Suire S, Coadwell J, Ferguson GJ, Davidson K, Hawkins P, Stephens L. (2005). p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma. Curr Biol 15: 566-570.
-
(2005)
Curr Biol
, vol.15
, pp. 566-570
-
-
Suire, S.1
Coadwell, J.2
Ferguson, G.J.3
Davidson, K.4
Hawkins, P.5
Stephens, L.6
-
27
-
-
0034653608
-
The PI3K-PDK1 connection: More than just a road to PKB
-
Vanhaesebroeck B, Alessi DR. (2000). The PI3K-PDK1 connection: more than just a road to PKB. Biochem J 346: 561-576.
-
(2000)
Biochem J
, vol.346
, pp. 561-576
-
-
Vanhaesebroeck, B.1
Alessi, D.R.2
-
28
-
-
0030611198
-
P110delta, a novel phosphoinositide 3-kinase in leukocytes
-
Vanhaesebroeck B, Welham MJ, Kotani K, Stein R, Warne PH, Zvelebil MJ et al. (1997). P110delta, a novel phosphoinositide 3-kinase in leukocytes. Proc Natl Acad Sci USA 94: 4330-4335.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4330-4335
-
-
Vanhaesebroeck, B.1
Welham, M.J.2
Kotani, K.3
Stein, R.4
Warne, P.H.5
Zvelebil, M.J.6
-
29
-
-
14244266719
-
Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma
-
Voigt P, Brock C, Nurnberg B, Schaefer M. (2005). Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma. J Biol Chem 280: 5121-5127.
-
(2005)
J Biol Chem
, vol.280
, pp. 5121-5127
-
-
Voigt, P.1
Brock, C.2
Nurnberg, B.3
Schaefer, M.4
-
30
-
-
33744518663
-
Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B
-
Voigt P, Dorner MB, Schaefer M. (2006). Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B. J Biol Chem 281: 9977-9986.
-
(2006)
J Biol Chem
, vol.281
, pp. 9977-9986
-
-
Voigt, P.1
Dorner, M.B.2
Schaefer, M.3
-
31
-
-
0036841057
-
Genomic gain of PIK3CA and increased expression of p110alpha are associated with progression of dysplasia into invasive squamous cell carcinoma
-
Woenckhaus J, Steger K, Werner E, Fenic I, Gamerdinger U, Dreyer T et al. (2002). Genomic gain of PIK3CA and increased expression of p110alpha are associated with progression of dysplasia into invasive squamous cell carcinoma. J Pathol 198: 335-342.
-
(2002)
J Pathol
, vol.198
, pp. 335-342
-
-
Woenckhaus, J.1
Steger, K.2
Werner, E.3
Fenic, I.4
Gamerdinger, U.5
Dreyer, T.6
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