Cancer-specific mutations in PIK3CA are oncogenic in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 5, 2006, Pages 1475-1479

  Bader, Andreas G ^a   Kang, Sohye ^a   Vogt, Peter K ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Chorioallantoic membrane; Hemangiosarcoma; p110; Phosphatidylinositol 3 kinase

Indexed keywords

EVEROLIMUS; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P110; PROTEIN P110ALPHA; TARGET OF RAPAMYCIN KINASE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANGIOSARCOMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENICITY; CHICK EMBRYO; CHORIOALLANTOIS; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME SUBUNIT; FOWL; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; MUTANT; NONHUMAN; ONCOGENE; PIK3CA GENE; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL MEMBRANE; CELLS, CULTURED; CHICK EMBRYO; CHICKENS; CHORIOALLANTOIC MEMBRANE; DISEASE MODELS, ANIMAL; HEMANGIOSARCOMA; HUMANS; MICROGLIA; MUTATION; NEOPLASMS; PLACEBOS; SIGNAL TRANSDUCTION; SIROLIMUS; TIME FACTORS; TRANSFECTION;

ANIMALIA; AVES;

EID: 31944444234     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0510857103     Document Type: Article

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