Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities

Nucleic Acids Research

Volumn 35, Issue 18, 2007, Pages

  Ichihara, Masatoshi ^a,b   Murakumo, Yoshiki ^b   Masuda, Akio ^b   Matsuura, Toru ^b   Asai, Naoya ^b   Jijiwa, Mayumi ^b   Ishida, Maki ^b   Shinmi, Jun ^b   Yatsuya, Hiroshi ^c   Qiao, Shanlou ^a   Takahashi, Masahide ^b   Ohno, Kinji ^b  

^a CHUBU UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Nagoya University   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

SMALL INTERFERING RNA;

ACCURACY; ARTICLE; CELL STRAIN HEK293; COMPUTER MODEL; CONTROLLED STUDY; DATA ANALYSIS; GENE ACTIVITY; GENETIC ALGORITHM; HUMAN; HUMAN CELL; LINEAR REGRESSION ANALYSIS; NUCLEIC ACID ANALYSIS; PREDICTION; PRIORITY JOURNAL; RNA SEQUENCE; RNA STABILITY; SCORING SYSTEM; SEQUENCE ANALYSIS; THERMODYNAMICS; ALGORITHM; CELL LINE; CHEMISTRY; GENOME; RNA INTERFERENCE; STATISTICAL MODEL; VALIDATION STUDY;

ALGORITHMS; CELL LINE; GENOME, HUMAN; HUMANS; LINEAR MODELS; RNA INTERFERENCE; RNA STABILITY; RNA, SMALL INTERFERING; THERMODYNAMICS;

EID: 35548980865     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkm699     Document Type: Article

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