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Volumn 26, Issue 9, 2007, Pages 683-694

N-methyl-N′-nitro-N-nitrosoguanidine activates multiple cell death mechanisms in human fibroblasts

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CASPASE 3; LIPOCORTIN 5; METHYLNITRONITROSOGUANIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; CASPASE; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; ENZYME INHIBITOR; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN;

EID: 35448943937     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.2007.0594     Document Type: Article
Times cited : (10)

References (65)
  • 1
    • 14844331767 scopus 로고    scopus 로고
    • Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2
    • Adamson, A.W., Beardsley, D.I., Kim, W.J., Gao, Y., Baskaran, R., and Brown, K.D. (2005). Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2. Mol Biol Cell 16, 1513-1526.
    • (2005) Mol Biol Cell , vol.16 , pp. 1513-1526
    • Adamson, A.W.1    Beardsley, D.I.2    Kim, W.J.3    Gao, Y.4    Baskaran, R.5    Brown, K.D.6
  • 2
    • 0037064053 scopus 로고    scopus 로고
    • ATM is activated in response to N-methyl-N′-nitro-N- nitrosoguanidine-induced DNA alkylation
    • Adamson, A.W., Kim, W.J., Shangary, S., Baskaran, R., and Brown, K.D. (2002). ATM is activated in response to N-methyl-N′-nitro-N- nitrosoguanidine-induced DNA alkylation. J Biol Chem 277, 38222-38229.
    • (2002) J Biol Chem , vol.277 , pp. 38222-38229
    • Adamson, A.W.1    Kim, W.J.2    Shangary, S.3    Baskaran, R.4    Brown, K.D.5
  • 4
    • 0030667522 scopus 로고    scopus 로고
    • Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways
    • Barlow, C., Brown, K.D., Deng, C.-X., Tagle, D.A., and Wynshaw-Boris, A. (1997). Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways. Nat Genet 17, 453-456.
    • (1997) Nat Genet , vol.17 , pp. 453-456
    • Barlow, C.1    Brown, K.D.2    Deng, C.-X.3    Tagle, D.A.4    Wynshaw-Boris, A.5
  • 8
    • 25144465117 scopus 로고    scopus 로고
    • N-methyl-N′- nitro-N-nitrosoguanidine activates cell-cycle arrest through distinct mechanisms activated in a dose-dependent manner
    • Beardsley, D.I., Kim, W.J., and Brown, K.D. (2005). N-methyl-N′- nitro-N-nitrosoguanidine activates cell-cycle arrest through distinct mechanisms activated in a dose-dependent manner. Mol Pharmacol 68, 1049-1060.
    • (2005) Mol Pharmacol , vol.68 , pp. 1049-1060
    • Beardsley, D.I.1    Kim, W.J.2    Brown, K.D.3
  • 9
    • 0033364285 scopus 로고    scopus 로고
    • A multiple ATM-dependent pathways: An explanation for pleiotropy
    • Brown, K.D., Barlow, C., and Wynshaw-Boris, A. (1999). A multiple ATM-dependent pathways: an explanation for pleiotropy. Am J Hum Genet 64, 46-50.
    • (1999) Am J Hum Genet , vol.64 , pp. 46-50
    • Brown, K.D.1    Barlow, C.2    Wynshaw-Boris, A.3
  • 10
    • 12244268624 scopus 로고    scopus 로고
    • Apoptosis-inducing factor (AIF): Key to the conserved caspase-independent pathways of cell death?
    • Cande, C., Cecconi, F., Dessen, P., and Kroemer, G. (2002). Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death? J Cell Sci 115, 4727-4734.
    • (2002) J Cell Sci , vol.115 , pp. 4727-4734
    • Cande, C.1    Cecconi, F.2    Dessen, P.3    Kroemer, G.4
  • 12
    • 0038666505 scopus 로고    scopus 로고
    • One-step cellular caspase-3/7 assay
    • Carrasco, R.A., Stamm, N.B., and Patel, B.K. (2003). One-step cellular caspase-3/7 assay. Biotechniques 34, 1064-1067.
    • (2003) Biotechniques , vol.34 , pp. 1064-1067
    • Carrasco, R.A.1    Stamm, N.B.2    Patel, B.K.3
  • 13
    • 0022492499 scopus 로고
    • DNA strand breaks, NAD metabolism, and programmed cell death
    • Carson, D.A., Seto, S., Wasson, D.B., and Carrera, C.J. (1986). DNA strand breaks, NAD metabolism, and programmed cell death. Exp Cell Res 164, 273-281.
    • (1986) Exp Cell Res , vol.164 , pp. 273-281
    • Carson, D.A.1    Seto, S.2    Wasson, D.B.3    Carrera, C.J.4
  • 14
    • 0029970505 scopus 로고    scopus 로고
    • Ionizing radiation-induced phosphorylation of RPA p34 is deficient in ataxia telangiectasia and reduced in aged normal fibroblasts
    • Cheng, X., Cheong, N., Wang, Y., and Iliakis, G. (1996). Ionizing radiation-induced phosphorylation of RPA p34 is deficient in ataxia telangiectasia and reduced in aged normal fibroblasts. Radiother Oncol 39, 43-52.
    • (1996) Radiother Oncol , vol.39 , pp. 43-52
    • Cheng, X.1    Cheong, N.2    Wang, Y.3    Iliakis, G.4
  • 16
    • 20444454999 scopus 로고    scopus 로고
    • Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction
    • Cipriani, G., Rapizzi, E., Vannacci, A., Rizzuto, R., Moroni, F., and Chiarugi, A. (2005). Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction. J Biol Chem 280, 17227-17234.
    • (2005) J Biol Chem , vol.280 , pp. 17227-17234
    • Cipriani, G.1    Rapizzi, E.2    Vannacci, A.3    Rizzuto, R.4    Moroni, F.5    Chiarugi, A.6
  • 17
    • 0028801762 scopus 로고
    • Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents - a case of imbalanced DNA repair
    • Coquerelle, T., Dosch, J., and Kaina, B. (1995). Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents - a case of imbalanced DNA repair. Mutat Res 336, 9-17.
    • (1995) Mutat Res , vol.336 , pp. 9-17
    • Coquerelle, T.1    Dosch, J.2    Kaina, B.3
  • 18
    • 0033527717 scopus 로고    scopus 로고
    • Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
    • Cortez, D., Wang, Y., Qin, J., and Elledge, S.J. (1999). Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science 286, 1162-1166.
    • (1999) Science , vol.286 , pp. 1162-1166
    • Cortez, D.1    Wang, Y.2    Qin, J.3    Elledge, S.J.4
  • 19
    • 2442621492 scopus 로고    scopus 로고
    • Role of AIF in caspase-dependent and caspase-independent cell death
    • Cregan, S.P., Dawson, V.L., and Slack, R.S. (2004). Role of AIF in caspase-dependent and caspase-independent cell death. Oncogene 23, 2785-2796.
    • (2004) Oncogene , vol.23 , pp. 2785-2796
    • Cregan, S.P.1    Dawson, V.L.2    Slack, R.S.3
  • 20
    • 0344699398 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase activity is not affected in ataxia telangiectasia cells and knockout mice
    • Dantzer, F., Menissier-de Murcia, J., Barlow, C., Wynshaw-Boris, A., and de Murcia, G. (1999). Poly(ADP-ribose) polymerase activity is not affected in ataxia telangiectasia cells and knockout mice. Carcinogenesis 20, 177-180.
    • (1999) Carcinogenesis , vol.20 , pp. 177-180
    • Dantzer, F.1    Menissier-de Murcia, J.2    Barlow, C.3    Wynshaw-Boris, A.4    de Murcia, G.5
  • 21
    • 1542358851 scopus 로고    scopus 로고
    • Loss of ATM sensitizes against O6-methylguanine triggered apoptosis, SCEs and chromosomal aberrations
    • Debiak, M., Nikolova, T., and Kaina, B. (2004). Loss of ATM sensitizes against O6-methylguanine triggered apoptosis, SCEs and chromosomal aberrations. DNA Repair (Amst) 3, 359-368.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 359-368
    • Debiak, M.1    Nikolova, T.2    Kaina, B.3
  • 22
    • 0347601880 scopus 로고    scopus 로고
    • A decade of caspases
    • Degterev, A., Boyce, M., and Yuan, J. (2003). A decade of caspases. Oncogene 22, 8543-8567.
    • (2003) Oncogene , vol.22 , pp. 8543-8567
    • Degterev, A.1    Boyce, M.2    Yuan, J.3
  • 23
    • 0026323008 scopus 로고
    • Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: Definition of a family of DNA repair enzymes
    • Demple, B., Herman, T., and Chen, D.S. (1991). Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes. Proc Natl Acad Sci USA 88, 11450-11454.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 11450-11454
    • Demple, B.1    Herman, T.2    Chen, D.S.3
  • 24
    • 0344823710 scopus 로고    scopus 로고
    • Apoptosis induced by MNNG in human TK6 lymphoblastoid cells is p53 and Fas/CD95/Apo-1 related
    • Dunkern, T., Roos, W., and Kaina, B. (2003). Apoptosis induced by MNNG in human TK6 lymphoblastoid cells is p53 and Fas/CD95/Apo-1 related. Mutat Res 544, 167-172.
    • (2003) Mutat Res , vol.544 , pp. 167-172
    • Dunkern, T.1    Roos, W.2    Kaina, B.3
  • 25
    • 0032885388 scopus 로고    scopus 로고
    • Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
    • Earnshaw, W.C., Martins, L.M., and Kaufmann, S.H. (1999). Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem 68, 383-424.
    • (1999) Annu Rev Biochem , vol.68 , pp. 383-424
    • Earnshaw, W.C.1    Martins, L.M.2    Kaufmann, S.H.3
  • 26
    • 7744235672 scopus 로고    scopus 로고
    • Death by design: Apoptosis, necrosis, and autophagy
    • Edinger, A.L., and Thompson, C.B. (2004). Death by design: apoptosis, necrosis, and autophagy. Curr Opin Cell Biol 16, 663-669.
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 663-669
    • Edinger, A.L.1    Thompson, C.B.2
  • 28
    • 24744439538 scopus 로고    scopus 로고
    • Chromatin architecture and functions: The role(s) of poly(ADP-RIBOSE) polymerase and poly(ADPribosyl)ation of nuclear proteins
    • Faraone-Mennella, M.R. (2005). Chromatin architecture and functions: the role(s) of poly(ADP-RIBOSE) polymerase and poly(ADPribosyl)ation of nuclear proteins. Biochem Cell Biol 83, 396-404.
    • (2005) Biochem Cell Biol , vol.83 , pp. 396-404
    • Faraone-Mennella, M.R.1
  • 29
    • 0037734244 scopus 로고    scopus 로고
    • Variation in radiation-induced apoptosis in ataxia telangiectasia lymphoblastoid cell lines
    • Fernet, M., Angele, S., Dork, T., and Hall, J. (2003). Variation in radiation-induced apoptosis in ataxia telangiectasia lymphoblastoid cell lines. Int J Radiat Biol 79, 193-202.
    • (2003) Int J Radiat Biol , vol.79 , pp. 193-202
    • Fernet, M.1    Angele, S.2    Dork, T.3    Hall, J.4
  • 32
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross, A., McDonnell, J.M., and Korsmeyer, S.J. (1999). BCL-2 family members and the mitochondria in apoptosis. Genes Dev 13, 1899-1911.
    • (1999) Genes Dev , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 33
    • 0033598713 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
    • Ha, H.C., and Snyder, S.H. (1999). Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc Natl Acad Sci USA 96, 13978-13982.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13978-13982
    • Ha, H.C.1    Snyder, S.H.2
  • 35
    • 0032524070 scopus 로고    scopus 로고
    • Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system
    • Herzog, K.H., Chong, M.J., Kapsetaki, M., Morgan, J.I., and McKinnon, P.J. (1998). Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science 280, 1089-1091.
    • (1998) Science , vol.280 , pp. 1089-1091
    • Herzog, K.H.1    Chong, M.J.2    Kapsetaki, M.3    Morgan, J.I.4    McKinnon, P.J.5
  • 36
    • 0032851842 scopus 로고    scopus 로고
    • Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
    • Hickman, M.J., and Samson, L.D. (1999). Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents. Proc Natl Acad Sci USA 96, 10764-10769.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10764-10769
    • Hickman, M.J.1    Samson, L.D.2
  • 37
    • 0023821527 scopus 로고
    • O6-methylguanine-DNA methyltransferase-defective human cell mutant: O6-methylguanine, DNA strand breaks and cytotoxicity
    • Kalamegham, R., Warmels-Rodenhiser, S., MacDonald, H., and Ebisuzaki, K. (1988). O6-methylguanine-DNA methyltransferase-defective human cell mutant: O6-methylguanine, DNA strand breaks and cytotoxicity. Carcinogenesis 9, 1749-1753.
    • (1988) Carcinogenesis , vol.9 , pp. 1749-1753
    • Kalamegham, R.1    Warmels-Rodenhiser, S.2    MacDonald, H.3    Ebisuzaki, K.4
  • 38
    • 0034576494 scopus 로고    scopus 로고
    • The many substrates and functions of ATM
    • Kastan, M.B., and Lim, D.S. (2000). The many substrates and functions of ATM. Nat Rev Mol Cell Biol 1, 179-186.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 179-186
    • Kastan, M.B.1    Lim, D.S.2
  • 39
    • 10044282525 scopus 로고    scopus 로고
    • The monofunctional alkylating agent N-methyl-N′-nitro-N-nitrosoguanidine triggers apoptosis through p53-dependent and -independent pathways
    • Kim, W.J., Beardsley, D.I., Adamson, A.W., and Brown, K.D. (2005). The monofunctional alkylating agent N-methyl-N′-nitro-N-nitrosoguanidine triggers apoptosis through p53-dependent and -independent pathways. Toxicol Appl Pharmacol 202, 84-98.
    • (2005) Toxicol Appl Pharmacol , vol.202 , pp. 84-98
    • Kim, W.J.1    Beardsley, D.I.2    Adamson, A.W.3    Brown, K.D.4
  • 40
    • 0034699378 scopus 로고    scopus 로고
    • Detection of dead cells and measurement of cell killing by flow cytometry
    • King, M.A. (2000). Detection of dead cells and measurement of cell killing by flow cytometry. J Immunol Methods 243, 155-166.
    • (2000) J Immunol Methods , vol.243 , pp. 155-166
    • King, M.A.1
  • 43
    • 28444433678 scopus 로고    scopus 로고
    • The two edges of the ATM sword: Co-operation between repair and checkpoint functions
    • Lobrich, M., and Jeggo, P.A. (2005). The two edges of the ATM sword: co-operation between repair and checkpoint functions. Radiother Oncol 76, 112-118.
    • (2005) Radiother Oncol , vol.76 , pp. 112-118
    • Lobrich, M.1    Jeggo, P.A.2
  • 44
    • 0023015325 scopus 로고
    • Mutagenesis by apurinic/ apyrimidinic sites
    • Loeb, L.A., and Preston, B.D. (1986). Mutagenesis by apurinic/ apyrimidinic sites. Annu Rev Genet 20, 201-230.
    • (1986) Annu Rev Genet , vol.20 , pp. 201-230
    • Loeb, L.A.1    Preston, B.D.2
  • 47
    • 0035131124 scopus 로고    scopus 로고
    • Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development
    • Menisser-de Murcia, J., Mark, M., Wendling, O., Wynshaw-Boris, A., and de Murcia, G. (2001). Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development. Mol Cell Biol 21, 1828-1832.
    • (2001) Mol Cell Biol , vol.21 , pp. 1828-1832
    • Menisser-de Murcia, J.1    Mark, M.2    Wendling, O.3    Wynshaw-Boris, A.4    de Murcia, G.5
  • 49
    • 0034731455 scopus 로고    scopus 로고
    • Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins
    • Pleschke, J.M., Kleczkowska, H.E., Strohm, M., and Althaus, F.R. (2000). Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins. J Biol Chem 275, 40974-40980.
    • (2000) J Biol Chem , vol.275 , pp. 40974-40980
    • Pleschke, J.M.1    Kleczkowska, H.E.2    Strohm, M.3    Althaus, F.R.4
  • 50
    • 14844328621 scopus 로고    scopus 로고
    • Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria
    • Polster, B.M., Basanez, G., Etxebarria, A., Hardwick, J.M., and Nicholls, D.G. (2005). Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. J Biol Chem 280, 6447-6454.
    • (2005) J Biol Chem , vol.280 , pp. 6447-6454
    • Polster, B.M.1    Basanez, G.2    Etxebarria, A.3    Hardwick, J.M.4    Nicholls, D.G.5
  • 51
    • 0031663617 scopus 로고    scopus 로고
    • ATM: From gene to function
    • Rotman, G., and Shiloh, Y. (1998). ATM: from gene to function. Hum Mol Genet 7, 1555-1563.
    • (1998) Hum Mol Genet , vol.7 , pp. 1555-1563
    • Rotman, G.1    Shiloh, Y.2
  • 53
    • 0019802321 scopus 로고
    • Kinetics of O6-methylguanine repair in human normal and ataxia telangiectasia cell lines and correlation of repair capacity with cellular sensitivity to methylating agents
    • Shiloh, Y., and Becker, Y. (1981). Kinetics of O6-methylguanine repair in human normal and ataxia telangiectasia cell lines and correlation of repair capacity with cellular sensitivity to methylating agents. Cancer Res 41, 5114-5120.
    • (1981) Cancer Res , vol.41 , pp. 5114-5120
    • Shiloh, Y.1    Becker, Y.2
  • 54
    • 0032516831 scopus 로고    scopus 로고
    • Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps
    • Srivastava, D.K., Berg, B.J., Prasad, R., Molina, J.T., Beard, W.A., Tomkinson, A.E., and Wilson, S.H. (1998). Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps. J Biol Chem 273, 21203-21209.
    • (1998) J Biol Chem , vol.273 , pp. 21203-21209
    • Srivastava, D.K.1    Berg, B.J.2    Prasad, R.3    Molina, J.T.4    Beard, W.A.5    Tomkinson, A.E.6    Wilson, S.H.7
  • 55
    • 23944504804 scopus 로고    scopus 로고
    • High doses of S(N)1 type methylating agents activate DNA damage signaling cascades that are largely independent of mismatch repair
    • Stojic, L., Cejka, P., and Jiricny, J. (2005). High doses of S(N)1 type methylating agents activate DNA damage signaling cascades that are largely independent of mismatch repair. Cell Cycle 4, 473-477.
    • (2005) Cell Cycle , vol.4 , pp. 473-477
    • Stojic, L.1    Cejka, P.2    Jiricny, J.3
  • 57
    • 0037472087 scopus 로고    scopus 로고
    • Escherichia coli uracil- and ethenocytosine-initiated base excision DNA repair: Rate-limiting step and patch size distribution
    • Sung, J.S., and Mosbaugh, D.W. (2003). Escherichia coli uracil- and ethenocytosine-initiated base excision DNA repair: rate-limiting step and patch size distribution. Biochemistry 42, 4613-4625.
    • (2003) Biochemistry , vol.42 , pp. 4613-4625
    • Sung, J.S.1    Mosbaugh, D.W.2
  • 59
    • 24644479304 scopus 로고    scopus 로고
    • Apaf-1 deficient mouse fibroblasts are resistant to MNNG and MMS-induced apoptotic death without attenuation of Bcl-2 decline
    • Tomicic, M.T., Christmann, M., Fabian, K., and Kaina, B. (2005). Apaf-1 deficient mouse fibroblasts are resistant to MNNG and MMS-induced apoptotic death without attenuation of Bcl-2 decline. Toxicol Appl Pharmacol 207, 117-122.
    • (2005) Toxicol Appl Pharmacol , vol.207 , pp. 117-122
    • Tomicic, M.T.1    Christmann, M.2    Fabian, K.3    Kaina, B.4
  • 60
    • 0036733355 scopus 로고    scopus 로고
    • The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
    • Virag, L., and Szabo, C. (2002). The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 54, 375-429.
    • (2002) Pharmacol Rev , vol.54 , pp. 375-429
    • Virag, L.1    Szabo, C.2
  • 61
    • 14644404266 scopus 로고    scopus 로고
    • Mechanism of early biphasic activation of poly(ADP-ribose) polymerase-1 in response to ultraviolet B radiation
    • Vodenicharov, M.D., Ghodgaonkar, M.M., Halappanavar, S.S., Shah, R.G., and Shah, G.M. (2005). Mechanism of early biphasic activation of poly(ADP-ribose) polymerase-1 in response to ultraviolet B radiation. J Cell Sci 118, 589-599.
    • (2005) J Cell Sci , vol.118 , pp. 589-599
    • Vodenicharov, M.D.1    Ghodgaonkar, M.M.2    Halappanavar, S.S.3    Shah, R.G.4    Shah, G.M.5
  • 62
    • 0033180391 scopus 로고    scopus 로고
    • 3-methyladenine DNA glycosylases: Structure, function, and biological importance
    • Wyatt, M.D., Allan, J.M., Lau, A.Y., Ellenberger, T.E., and Samson, L.D. (1999). 3-methyladenine DNA glycosylases: structure, function, and biological importance. Bioessays 21, 668-676.
    • (1999) Bioessays , vol.21 , pp. 668-676
    • Wyatt, M.D.1    Allan, J.M.2    Lau, A.Y.3    Ellenberger, T.E.4    Samson, L.D.5
  • 65
    • 2642536197 scopus 로고    scopus 로고
    • Alkylating DNA damage stimulates a regulated form of necrotic cell death
    • Zong, W.X., Ditsworth, D., Bauer, D.E., Wang, Z.Q., and Thompson, C.B. (2004). Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 18, 1272-1282.
    • (2004) Genes Dev , vol.18 , pp. 1272-1282
    • Zong, W.X.1    Ditsworth, D.2    Bauer, D.E.3    Wang, Z.Q.4    Thompson, C.B.5


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