Identification of small molecules that sensitize resistant tumor cells to tumor necrosis factor-family death receptors

Cancer Research

Volumn 66, Issue 4, 2006, Pages 2367-2375

  Schimmer, Aaron D ^a,b,c   Thomas, Michael P ^a   Hurren, Rose ^b   Gronda, Marcela ^b   Pellecchia, Maurizio ^a   Pond, Gregory R ^b   Konopleva, Marina ^d   Gurfinkel, Debbie ^b   Mawji, Imtiaz A ^b   Brown, Ewan ^b   Reed, John C ^a  

^a BURNHAM INSTITUTE   (United States)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c McLaughlin Centre for Molecular Medicine   (Canada)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [(4 CHLOROPHENYL)ACETYL] 4 (3 PHENYLPROP 2 ENYL)PIPERAZINE; 4 (CHLORO 2 METHYLPHENOXY) N HYDROXYBUTANAMIDE; CASPASE; CASPASE PROTEASE ACTIVATOR; DEATH RECEPTOR; ENZYME ACTIVATOR; ETOPOSIDE; FAS ANTIBODY; FAS ANTIGEN; FLICE INHIBITORY PROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CH11; N [4 CHLORO 3 (TRIFLUOROMETHYL)PHENYL] 3 OXOBUTANAMIDE; PROTEINASE; STAUROSPORINE; TISSUE FACTOR PATHWAY INHIBITOR; TUMOR NECROSIS FACTOR FAMILY DEATH RECEPTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL STRAIN PPC 1; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG POTENTIATION; ENZYME ACTIVATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMMUNITY; MITOCHONDRION; PHARMACOPHORE; PRIORITY JOURNAL; PROSTATE CANCER; SENSITIZATION; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE; TUMOR RESISTANCE;

ANTIBODIES; ANTIGENS, CD95; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASES; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; ETOPOSIDE; HUMANS; LIGANDS; MALE; MEMBRANE GLYCOPROTEINS; PROSTATIC NEOPLASMS; RECEPTORS, TUMOR NECROSIS FACTOR; STAUROSPORINE; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33644539489     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-1061     Document Type: Article

References (20)

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