Molecular mechanism of the sea anemone toxin ShK recognizing the Kv1.3 channel explored by docking and molecular dynamic simulations

Journal of Chemical Information and Modeling

Volumn 47, Issue 5, 2007, Pages 1967-1972

  Ling, Jin ^a   Yingliang, Wu ^b  

^a WUHAN UNIVERSITY OF TECHNOLOGY   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CLUSTERING ALGORITHMS; COMPUTER SIMULATION; DOCKING; MOLECULAR DYNAMICS; OPTIMIZATION; POTASSIUM;

POTASSIUM CHANNELS; PROTEIN DATA BANKS; TRADITIONAL MODELS;

TOXIC MATERIALS;

ALANINE; COELENTERATE VENOM; IMMUNOSUPPRESSIVE AGENT; POTASSIUM CHANNEL KV1.3; SHK NEUROTOXIN;

ALGORITHM; ANIMAL; ARTICLE; CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; DRUG EFFECT; FACTUAL DATABASE; HYDROGEN BOND; METABOLISM; MOUSE; PROTEIN BINDING; PROTEIN CONFORMATION; STEREOISOMERISM; STREPTOMYCES LIVIDANS; STRUCTURE ACTIVITY RELATION;

ALANINE; ALGORITHMS; ANIMALS; CNIDARIAN VENOMS; COMPUTER SIMULATION; DATABASES, FACTUAL; HYDROGEN BONDING; IMMUNOSUPPRESSIVE AGENTS; KV1.3 POTASSIUM CHANNEL; MICE; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; STEREOISOMERISM; STREPTOMYCES LIVIDANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 35248857005     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci700178w     Document Type: Article

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