A variable residue in the pore of Kv1 channels is critical for the high affinity of blockers from sea anemones and scorpions

Journal of Biological Chemistry

Volumn 280, Issue 29, 2005, Pages 27093-27102

  Gilquin, Bernard ^a   Braud, Sandrine ^a   Eriksson, Mats A L ^b   Roux, Benoît ^b   Bailey, Timothy D ^c   Priest, Birgit T ^c   Garcia, Maria L ^c   Ménez, André ^a   Gasparini, Sylvaine ^a  

^a CEA SACLAY   (France)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; ELECTROPHYSIOLOGY; FREE ENERGY; MOLECULAR DYNAMICS; TOXIC MATERIALS;

ANIMAL TOXINS; CHANNELS CONTROL; SEA ANEMONE TOXIN;

LIVING SYSTEMS STUDIES;

POTASSIUM CHANNEL; SHAKER POTASSIUM CHANNEL; TOXIN; TYROSINE; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHANNEL GATING; ELECTROPHYSIOLOGY; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; RESIDUE ANALYSIS; SCORPION; SEA ANEMONE; STRUCTURE ANALYSIS;

ACTINIARIA; ANIMALIA; SCORPIONES;

EID: 22844448219     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413626200     Document Type: Article

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